Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis

Nature Genetics

Volumn 45, Issue 3, 2013, Pages 308-313

  Twigg, Stephen R F ^a   Vorgia, Elena ^b,c   Mcgowan, Simon J ^a   Peraki, Ioanna ^b,c   Fenwick, Aimée L ^a   Sharma, Vikram P ^a,d   Allegra, Maryline ^b   Zaragkoulias, Andreas ^c   Akha, Elham Sadighi ^e   Knight, Samantha J L ^e   Lord, Helen ^d   Lester, Tracy ^d   Izatt, Louise ^f   Lampe, Anne K ^g   Mohammed, Shehla N ^f   Stewart, Fiona J ^h   Verloes, Alain ⁱ   Wilson, Louise C ^j   Healy, Chris ^k   Sharpe, Paul T ^k   Hammond, Peter ^l   Hughes, Jim ^a   Taylor, Stephen ^a   Johnson, David ^d   Wall, Steven A ^d   Mavrothalassitis, George ^b,c   Wilkie, Andrew O M ^a,d   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

^d OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^g NHS LOTHIAN   (United Kingdom)

^h BELFAST CITY HOSPITAL   (United Kingdom)

ⁱ ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^j GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^k KING'S COLLEGE LONDON   (United Kingdom)

^l UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARNOLD CHIARI MALFORMATION; ARTICLE; BONE DEVELOPMENT; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CRANIOFACIAL SYNOSTOSIS; ERF GENE; FEMALE; FIBROBLAST; GENE; GENE DOSAGE; HIGH THROUGHPUT SEQUENCING; HUMAN; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LANGUAGE DISABILITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CORE BINDING FACTOR ALPHA SUBUNITS; CRANIAL SUTURES; CRANIOSYNOSTOSES; EMBRYONIC DEVELOPMENT; FIBROBLASTS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OSTEOGENESIS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

MUS;

EID: 84874583377     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2539     Document Type: Article

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