Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins

Journal of Experimental Medicine

Volumn 210, Issue 2, 2013, Pages 225-232

  Dev, Arvind ^a   Byrne, Susan M ^b   Verma, Rakesh ^a   Ashton Rickardt, Philip G ^b   Wojchowski, D M ^a  

^a Maine Medical Center Research Institute   (Canada)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; HEMOGLOBIN; REACTIVE OXYGEN METABOLITE; SERINE PROTEINASE INHIBITOR; SERPINA3G; UNCLASSIFIED DRUG;

ALLELE; ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BASOPHIL; CELL PROTECTION; CONFOCAL MICROSCOPY; EOSINOPHIL; ERYTHROBLAST; ERYTHROCYTE; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; FLOW CYTOMETRY; GENOTYPE; KNOCKOUT MOUSE; LEUKOCYTE; LYMPHOCYTE; LYSOSOME; MONOCYTE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SECRETION; THROMBOCYTE;

ANEMIA; ANIMALS; CATHEPSIN B; CATHEPSIN L; CATHEPSINS; ERYTHROBLASTS; ERYTHROPOIESIS; ERYTHROPOIETIN; LYSOSOMES; MICE; MICE, KNOCKOUT; RECEPTORS, ERYTHROPOIETIN; SERPINS; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84874557275     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121762     Document Type: Article

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