Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Ruiz Alcaraz, Antonio J ^a   Lipina, Christopher ^b   Petrie, John R ^c   Murphy, Michael J ^b   Morris, Andrew D ^b   Sutherland, Calum ^b   Cuthbertson, Daniel J ^d,e  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; S6 KINASE; TRANSCRIPTION FACTOR FOXO;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FAT MASS; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; IMMUNOPRECIPITATION; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MOLECULAR DYNAMICS; MUSCLE BIOPSY; OBESITY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASTUS LATERALIS MUSCLE; WESTERN BLOTTING;

ADULT; BLOOD GLUCOSE; BODY COMPOSITION; ENZYME ACTIVATION; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SKELETAL; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84874546147     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056928     Document Type: Article

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