Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action

Diabetologia

Volumn 53, Issue 9, 2010, Pages 1998-2007

  Friedrichsen, M ^a,b   Poulsen, P ^a   Richter, E A ^b   Hansen, B F ^c   Birk, J B ^b   Ribel Madsen, R ^a   Stender Petersen, K ^a   Nilsson, E ^a   Beck Nielsen, H ^d   Vaag, A ^a,e   Wojtaszewski, J F P ^b  

^a STENO DIABETES CENTER   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NOVO NORDISK A S   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

^e LUND UNIVERSITY   (Sweden)

Author keywords

Assay methods; Hormone receptors; Human; Insulin action; Insulin resistance; Insulin sensitivity

Indexed keywords

INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN;

ADULT; AEROBIC CAPACITY; AGE DISTRIBUTION; ARTICLE; BIRTH WEIGHT; BODY COMPOSITION; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HERITABILITY; HUMAN; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; INHERITANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; OXYGEN CONSUMPTION; PRENATAL PERIOD; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TWINS; WESTERN BLOTTING; ZYGOSITY; AGE; CLINICAL TRIAL; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; AGE FACTORS; BIRTH WEIGHT; BLOTTING, WESTERN; FEMALE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; OBESITY; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SEX FACTORS; SIGNAL TRANSDUCTION; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77955552494     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1795-8     Document Type: Article

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