The long noncoding RNA Kcnq 1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing

Development

Volumn 136, Issue 4, 2009, Pages 525-530

  Redrup, Lisa ^a   Branco, Miguel R ^a   Perdeaux, Elizabeth R ^a   Krueger, Christel ^a   Lewis, Annabelle ^a,b   Santos, Fátima ^a   Nagano, Takashi ^a   Cobb, Bradley S ^c,d   Fraser, Peter ^a   Reik, Wolf ^a,e  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b CRUK London Research Institute   (United Kingdom)

^c ROYAL VETERINARY COLLEGE   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Epigenetic gene silencing; Imprinting; Kcnq1ot1; Long noncoding RNA; X inactivation

Indexed keywords

DICER; RNA; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; CELL LINE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EPIGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE SILENCING; GENETIC REGULATION; MOUSE; MUTANT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION; RNA ISOLATION; X CHROMOSOME;

ANIMALS; BASE SEQUENCE; CELL LINEAGE; CELL NUCLEUS; GENE SILENCING; GENOMIC IMPRINTING; MICE; MOLECULAR SEQUENCE DATA; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; RNA, UNTRANSLATED;

EUKARYOTA;

EID: 60149092541     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.031328     Document Type: Article

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