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Volumn 33, Issue 3, 2013, Pages 501-509

Pericytes from infantile hemangioma display proangiogenic properties and dysregulated angiopoietin-1

Author keywords

angiogenesis; angiopoietin 1; endothelial colony forming cells; infantile hemangioma; pericytes; VEGF A

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOPOIETIN 1; ANTIGEN; CALPONIN; DESMIN; F ACTIN; MYOSIN HEAVY CHAIN; NEURAL GLIAL ANTIGEN 2; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; THY 1 ANTIGEN; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 84874389760     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300929     Document Type: Article
Times cited : (42)

References (62)
  • 1
    • 79961230399 scopus 로고    scopus 로고
    • Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
    • Armulik A, Genové G, Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell. 2011;21:193-215.
    • (2011) Dev Cell , vol.21 , pp. 193-215
    • Armulik, A.1    Genové, G.2    Betsholtz, C.3
  • 2
    • 80052667572 scopus 로고    scopus 로고
    • Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression
    • Franco M, Roswall P, Cortez E, Hanahan D, Pietras K. Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood. 2011;118:2906-2917.
    • (2011) Blood , vol.118 , pp. 2906-2917
    • Franco, M.1    Roswall, P.2    Cortez, E.3    Hanahan, D.4    Pietras, K.5
  • 3
    • 73949086144 scopus 로고    scopus 로고
    • Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation
    • Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. 2009;114:5091-5101.
    • (2009) Blood , vol.114 , pp. 5091-5101
    • Stratman, A.N.1    Malotte, K.M.2    Mahan, R.D.3    Davis, M.J.4    Davis, G.E.5
  • 5
    • 34548319112 scopus 로고    scopus 로고
    • Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state
    • Kutcher ME, Kolyada AY, Surks HK, Herman IM. Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. Am J Pathol. 2007;171:693-701.
    • (2007) Am J Pathol , vol.171 , pp. 693-701
    • Kutcher, M.E.1    Kolyada, A.Y.2    Surks, H.K.3    Herman, I.M.4
  • 7
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • Lindahl P, Johansson BR, Levéen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997; 277:242-245.
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Levéen, P.3    Betsholtz, C.4
  • 8
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellström M, Kalén M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999;126:3047-3055.
    • (1999) Development , vol.126 , pp. 3047-3055
    • Hellström, M.1    Kalén, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 11
    • 0242456268 scopus 로고    scopus 로고
    • Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
    • Darland DC, Massingham LJ, Smith SR, Piek E, Saint-Geniez M, D'Amore PA. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol. 2003;264:275-288.
    • (2003) Dev Biol , vol.264 , pp. 275-288
    • Darland, D.C.1    Massingham, L.J.2    Smith, S.R.3    Piek, E.4    Saint-Geniez, M.5    D'Amore, P.A.6
  • 12
    • 0242405592 scopus 로고    scopus 로고
    • Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
    • Thurston G. Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis. Cell Tissue Res. 2003;314:61-68.
    • (2003) Cell Tissue Res , vol.314 , pp. 61-68
    • Thurston, G.1
  • 13
    • 0036223819 scopus 로고    scopus 로고
    • Stable expression of angiopoietin-1 and other markers by cultured pericytes: Phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo
    • Sundberg C, Kowanetz M, Brown LF, Detmar M, Dvorak HF. Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo. Lab Invest. 2002;82:387-401.
    • (2002) Lab Invest , vol.82 , pp. 387-401
    • Sundberg, C.1    Kowanetz, M.2    Brown, L.F.3    Detmar, M.4    Dvorak, H.F.5
  • 15
    • 0031845695 scopus 로고    scopus 로고
    • TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth
    • Patan S. TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth. Microvasc Res. 1998;56:1-21.
    • (1998) Microvasc Res , vol.56 , pp. 1-21
    • Patan, S.1
  • 16
    • 0035318510 scopus 로고    scopus 로고
    • Tie receptors: New modulators of angiogenic and lymphangiogenic responses
    • Jones N, Iljin K, Dumont DJ, Alitalo K. Tie receptors: new modulators of angiogenic and lymphangiogenic responses. Nat Rev Mol Cell Biol. 2001;2:257-267.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 257-267
    • Jones, N.1    Iljin, K.2    Dumont, D.J.3    Alitalo, K.4
  • 18
    • 84871719489 scopus 로고    scopus 로고
    • Orchestral actions of angiopoietin-1 in vascular regeneration
    • Koh GY. Orchestral actions of angiopoietin-1 in vascular regeneration. Trends Mol Med. 2013;1:31-39.
    • (2013) Trends Mol Med , vol.1 , pp. 31-39
    • Koh, G.Y.1
  • 21
    • 0035074539 scopus 로고    scopus 로고
    • Glucose VEGF-A and diabetic complications
    • Benjamin LE. Glucose, VEGF-A, and diabetic complications. Am J Pathol. 2001;158:1181-1184.
    • (2001) Am J Pathol , vol.158 , pp. 1181-1184
    • Benjamin, L.E.1
  • 23
    • 20444450179 scopus 로고    scopus 로고
    • Pericytes and the pathogenesis of diabetic retinopathy
    • Hammes HP. Pericytes and the pathogenesis of diabetic retinopathy. Horm Metab Res. 2005;37:39-43.
    • (2005) Horm Metab Res , vol.37 , pp. 39-43
    • Hammes, H.P.1
  • 25
    • 0032952010 scopus 로고    scopus 로고
    • Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
    • Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest. 1999;103:159-165.
    • (1999) J Clin Invest , vol.103 , pp. 159-165
    • Benjamin, L.E.1    Golijanin, D.2    Itin, A.3    Pode, D.4    Keshet, E.5
  • 26
    • 0034161989 scopus 로고    scopus 로고
    • Heterogeneity of angiogenesis and blood vessel maturation in human tumors: Implications for antiangiogenic tumor therapies
    • Eberhard A, Kahlert S, Goede V, Hemmerlein B, Plate KH, Augustin HG. Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. Cancer Res. 2000;60:1388-1393.
    • (2000) Cancer Res , vol.60 , pp. 1388-1393
    • Eberhard, A.1    Kahlert, S.2    Goede, V.3    Hemmerlein, B.4    Plate, K.H.5    Augustin, H.G.6
  • 27
    • 0002764794 scopus 로고
    • Hemangiopericytoma: A vascular tumor featuring Zimmermann's pericytes
    • Stout AP, Murray MR. Hemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes. Ann Surg. 1942;116:26-33.
    • (1942) Ann Surg , vol.116 , pp. 26-33
    • Stout, A.P.1    Murray, M.R.2
  • 28
    • 0025325887 scopus 로고
    • Intermediate filament proteins and actin isoforms as markers for soft-tissue tumor differentiation and origin. III. Hemangiopericytomas and glomus tumors
    • Schürch W, Skalli O, Lagacé R, Seemayer TA, Gabbiani G. Intermediate filament proteins and actin isoforms as markers for soft-tissue tumor differentiation and origin. III. Hemangiopericytomas and glomus tumors. Am J Pathol. 1990;136:771-786.
    • (1990) Am J Pathol , vol.136 , pp. 771-786
    • Schürch, W.1    Skalli, O.2    Lagacé, R.3    Seemayer, T.A.4    Gabbiani, G.5
  • 29
    • 0027142450 scopus 로고
    • Cutaneous vascular anomalies
    • Mulliken JB. Cutaneous vascular anomalies. Semin Vasc Surg. 1993;6:204-218.
    • (1993) Semin Vasc Surg , vol.6 , pp. 204-218
    • Mulliken, J.B.1
  • 30
    • 67650711112 scopus 로고    scopus 로고
    • Vasculogenesis in infantile hemangioma
    • Boscolo E, Bischoff J. Vasculogenesis in infantile hemangioma. Angiogenesis. 2009;12:197-207.
    • (2009) Angiogenesis , vol.12 , pp. 197-207
    • Boscolo, E.1    Bischoff, J.2
  • 31
    • 0019988662 scopus 로고
    • Cellular haemangioma. Light and electron microscopic studies of two cases
    • Pasyk KA, Grabb WC, Cherry GW. Cellular haemangioma. Light and electron microscopic studies of two cases. Virchows Arch A Pathol Anat Histol. 1982;396:103-126.
    • (1982) Virchows Arch A Pathol Anat Histol , vol.396 , pp. 103-126
    • Pasyk, K.A.1    Grabb, W.C.2    Cherry, G.W.3
  • 32
    • 0027165965 scopus 로고
    • Infantile (juvenile) capillary hemangioma: A tumor of heterogeneous cellular elements
    • Smoller BR, Apfelberg DB. Infantile (juvenile) capillary hemangioma: a tumor of heterogeneous cellular elements. J Cutan Pathol. 1993;20:330-336.
    • (1993) J Cutan Pathol , vol.20 , pp. 330-336
    • Smoller, B.R.1    Apfelberg, D.B.2
  • 33
    • 0141961138 scopus 로고    scopus 로고
    • Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin
    • Li Q, Yu Y, Bischoff J, Mulliken JB, Olsen BR. Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin. J Pathol. 2003;201:296-302.
    • (2003) J Pathol , vol.201 , pp. 296-302
    • Li, Q.1    Yu, Y.2    Bischoff, J.3    Mulliken, J.B.4    Olsen, B.R.5
  • 36
    • 80054969284 scopus 로고    scopus 로고
    • VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma
    • Boscolo E, Mulliken JB, Bischoff J. VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma. Am J Pathol. 2011;179:2266-2277.
    • (2011) Am J Pathol , vol.179 , pp. 2266-2277
    • Boscolo, E.1    Mulliken, J.B.2    Bischoff, J.3
  • 37
    • 52049085327 scopus 로고    scopus 로고
    • Pericyte isolation and use in endothelial/pericyte coculture models
    • Bryan BA, D'Amore PA. Pericyte isolation and use in endothelial/pericyte coculture models. Meth Enzymol. 2008;443:315-331.
    • (2008) Meth Enzymol , vol.443 , pp. 315-331
    • Bryan, B.A.1    D'Amore, P.A.2
  • 38
    • 23944518957 scopus 로고    scopus 로고
    • Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells
    • Ingram DA, Caplice NM, Yoder MC. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood. 2005;106:1525-1531.
    • (2005) Blood , vol.106 , pp. 1525-1531
    • Ingram, D.A.1    Caplice, N.M.2    Yoder, M.C.3
  • 39
    • 34249732615 scopus 로고    scopus 로고
    • In vivo vasculogenic potential of human blood-derived endothelial progenitor cells
    • Melero-Martin JM, Khan ZA, Picard A, Wu X, Paruchuri S, Bischoff J. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood. 2007;109:4761-4768.
    • (2007) Blood , vol.109 , pp. 4761-4768
    • Melero-Martin, J.M.1    Khan, Z.A.2    Picard, A.3    Wu, X.4    Paruchuri, S.5    Bischoff, J.6
  • 40
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005;307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 43
    • 77953802129 scopus 로고    scopus 로고
    • The absence of pericytes does not increase the sensitivity of tumor vasculature to vascular endothelial growth factor-A blockade
    • Nisancioglu MH, Betsholtz C, Genové G. The absence of pericytes does not increase the sensitivity of tumor vasculature to vascular endothelial growth factor-A blockade. Cancer Res. 2010;70:5109-5115.
    • (2010) Cancer Res , vol.70 , pp. 5109-5115
    • Nisancioglu, M.H.1    Betsholtz, C.2    Genové, G.3
  • 44
    • 34547637867 scopus 로고    scopus 로고
    • Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
    • Sennino B, Falcón BL, McCauley D, Le T, McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res. 2007;67:7358-7367.
    • (2007) Cancer Res , vol.67 , pp. 7358-7367
    • Sennino, B.1    Falcón, B.L.2    McCauley, D.3    Le McCauley T, T.4    Kurz, J.C.5    Haskell, A.6    Epstein, D.M.7    McDonald, D.M.8
  • 45
    • 0345798150 scopus 로고    scopus 로고
    • Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
    • Abramsson A, Lindblom P, Betsholtz C. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest. 2003;112:1142-1151.
    • (2003) J Clin Invest , vol.112 , pp. 1142-1151
    • Abramsson, A.1    Lindblom, P.2    Betsholtz, C.3
  • 47
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 1998;125:1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 48
    • 28744431719 scopus 로고    scopus 로고
    • Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity
    • Hoffmann J, Feng Y, vom Hagen F, et al. Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity. FASEB J. 2005;19:2035-2036.
    • (2005) FASEB J , vol.19 , pp. 2035-2036
    • Hoffmann, J.1    Feng, Y.2    Vom Hagen, F.3
  • 49
    • 0040143484 scopus 로고    scopus 로고
    • Angiogenesis in the bovine corpus luteum: An immunocytochemical and ultrastructural study
    • Amselgruber WM, Schäfer M, Sinowatz F. Angiogenesis in the bovine corpus luteum: an immunocytochemical and ultrastructural study. Anat Histol Embryol. 1999;28:157-166.
    • (1999) Anat Histol Embryol , vol.28 , pp. 157-166
    • Amselgruber, W.M.1    Schäfer, M.2    Sinowatz, F.3
  • 50
    • 77949645298 scopus 로고    scopus 로고
    • Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells
    • Greenberger S, Boscolo E, Adini I, Mulliken JB, Bischoff J. Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med. 2010;362:1005-1013.
    • (2010) N Engl J Med , vol.362 , pp. 1005-1013
    • Greenberger, S.1    Boscolo, E.2    Adini, I.3    Mulliken, J.B.4    Bischoff, J.5
  • 54
    • 0038745370 scopus 로고    scopus 로고
    • Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
    • Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O'Brien-Jenkins A, Randall TC, Rubin SC, Coukos G. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res. 2003;63:3403-3412.
    • (2003) Cancer Res , vol.63 , pp. 3403-3412
    • Zhang, L.1    Yang, N.2    Park, J.W.3    Katsaros, D.4    Fracchioli, S.5    Cao, G.6    O'Brien-Jenkins, A.7    Randall, T.C.8    Rubin, S.C.9    Coukos, G.10
  • 55
    • 7944220649 scopus 로고    scopus 로고
    • Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2
    • Oliner J, Min H, Leal J, et al. Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. Cancer Cell. 2004;6:507-516.
    • (2004) Cancer Cell , vol.6 , pp. 507-516
    • Oliner, J.1    Min, H.2    Leal, J.3
  • 58
    • 0035180453 scopus 로고    scopus 로고
    • Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells
    • Yu Y, Varughese J, Brown LF, Mulliken JB, Bischoff J. Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells. Am J Pathol. 2001;159:2271-2280.
    • (2001) Am J Pathol , vol.159 , pp. 2271-2280
    • Yu, Y.1    Varughese, J.2    Brown, L.F.3    Mulliken, J.B.4    Bischoff, J.5
  • 59
    • 65649147941 scopus 로고    scopus 로고
    • Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling
    • Calicchio ML, Collins T, Kozakewich HP. Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling. Am J Pathol. 2009;174:1638-1649.
    • (2009) Am J Pathol , vol.174 , pp. 1638-1649
    • Calicchio, M.L.1    Collins, T.2    Kozakewich, H.P.3
  • 60
    • 60749096085 scopus 로고    scopus 로고
    • Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
    • Augustin HG, Koh GY, Thurston G, Alitalo K. Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol. 2009;10:165-177.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 165-177
    • Augustin, H.G.1    Koh, G.Y.2    Thurston, G.3    Alitalo, K.4
  • 62
    • 84865682077 scopus 로고    scopus 로고
    • Infantile Hemangioma-Mechanism(s) of Drug Action on a Vascular Tumor
    • Greenberger S, Bischoff J. Infantile Hemangioma-Mechanism(s) of Drug Action on a Vascular Tumor. Cold Spring Harb Perspect Med. 2011;1:a006460.
    • (2011) Cold Spring Harb Perspect Med , vol.1
    • Greenberger, S.1    Bischoff, J.2


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