Vasculogenesis in infantile hemangioma

Angiogenesis

Volumn 12, Issue 2, 2009, Pages 197-207

  Boscolo, Elisa ^a   Bischoff, Joyce ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Angiogenesis; Endothelial cells; Endothelial progenitor cells; Hemangioma; Vasculogenesis; VEGF receptors

Indexed keywords

CORTICOSTEROID; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ARTICLE; BONE MARROW CELL; CELL ISOLATION; CELL MATURATION; CELL POPULATION; CONGENITAL BLOOD VESSEL MALFORMATION; ENDOTHELIUM CELL; EUROPE; EXPLANT; GENE EXPRESSION REGULATION; GENE MUTATION; HEMANGIOMA; HUMAN; IMMATURITY; INFANT; LEYDIG CELL; MAST CELL; MULTIPOTENT STEM CELL; NONHUMAN; PERICYTE; POSTNATAL GROWTH; PRIORITY JOURNAL; STEM CELL; TISSUE STRUCTURE; TUMOR CELL; TUMOR GROWTH; VASCULAR TISSUE;

BLOOD VESSELS; HEMANGIOMA; HUMANS; INFANT; MORPHOGENESIS; MULTIPOTENT STEM CELLS;

EID: 67650711112     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10456-009-9148-2     Document Type: Article

References (82)

1. JB Mulliken SJ Fishman PE Burrows 2000 Vascular anomalies Curr Probl Surg 37 517 584
2. BA Drolet NB Esterly IJ Frieden 1999 Hemangiomas in children N Engl J Med 341 173 181 (Pubitemid 29325746)
3. AN Haggstrom BA Drolet E Baselga SL Chamlin MC Garzon KA Horii AW Lucky AJ Mancini DW Metry B Newell 2007 Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics J Pediatr 150 291 294 (Pubitemid 46328964)
4. Frieden IJ, Haggstrom AN, Drolet BA, Mancini AJ, Friedlander SF, Boon L, Chamlin SL, Baselga E, Garzon MC, Nopper AJ et al (2005) Infantile hemangiomas: current knowledge, future directions. In: Proceedings of a research workshop on infantile hemangiomas, April 7-9, 2005, Bethesda. Pediatr Dermatol 22:383-406
5. DW Metry AN Haggstrom BA Drolet E Baselga S Chamlin M Garzon K Horii A Lucky AJ Mancini B Newell 2006 A prospective study of PHACE syndrome in infantile hemangiomas: demographic features, clinical findings, and complications Am J Med Genet A 140 975 986
6. SA Huang HM Tu JW Harney M Venihaki AJ Butte HP Kozakewich SJ Fishman PR Larsen 2000 Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas N Engl J Med 343 185 189 (Pubitemid 30489216)
7. LM Boon DM [tmp] MacDonald JB Mulliken 1999 Complications of systemic corticosteroid therapy for problematic hemangioma Plast Reconstr Surg 104 1616 1623 (Pubitemid 29510480)
8. O Enjolras GM Breviere G Roger M Tovi B Pellegrino E Varotti V Soupre A Picard G Leverger 2004 Vincristine treatment for function- and life-threatening infantile hemangioma Arch Pediatr 11 99 107 (Pubitemid 38220704)
9. SL Fawcett I Grant PN Hall AW Kelsall JC Nicholson 2004 Vincristine as a treatment for a large haemangioma threatening vital functions Br J Plast Surg 57 168 171 (Pubitemid 38239893)
10. RA Ezekowitz JB Mulliken J Folkman 1992 Interferon alfa-2a therapy for life-threatening hemangiomas of infancy N Engl J Med 326 1456 1463
11. E Chang A Boyd CC Nelson D Crowley T Law KM Keough J Folkman RA Ezekowitz VP Castle 1997 Successful treatment of infantile hemangiomas with interferon-alpha-2b J Pediatr Hematol Oncol 19 237 244 (Pubitemid 27276291)
12. CF Barlow CJ Priebe JB Mulliken PD Barnes D Mac Donald J Folkman RA Ezekowitz 1998 Spastic diplegia as a complication of interferon Alfa-2a treatment of hemangiomas of infancy J Pediatr 132 527 530 (Pubitemid 28180264)
13. JH Greinwald Jr DK Burke DJ Bonthius NM Bauman RJ Smith 1999 An update on the treatment of hemangiomas in children with interferon alfa-2a Arch Otolaryngol Head Neck Surg 125 21 27 (Pubitemid 29074891)
14. C Leaute-Labreze E Dumas de la Roque T Hubiche F Boralevi JB Thambo A Taieb 2008 Propranolol for severe hemangiomas of infancy N Engl J Med 358 2649 2651 (Pubitemid 351831393)
15. LC Chang AN Haggstrom BA Drolet E Baselga SL Chamlin MC Garzon KA Horii AW Lucky AJ Mancini DW Metry 2008 Growth characteristics of infantile hemangiomas: implications for management Pediatrics 122 360 367
16. AJ Mancini BR Smoller 1996 Proliferation and apoptosis within juvenile capillary hemangiomas Am J Dermatopathol 18 505 514 (Pubitemid 26347271)
17. BR Smoller DB Apfelberg 1993 Infantile (juvenile) capillary hemangioma: a tumor of heterogeneous cellular elements J Cutan Pathol 20 330 336 (Pubitemid 23249612)
18. K Takahashi JB Mulliken HP Kozakewich RA Rogers J Folkman RA Ezekowitz 1994 Cellular markers that distinguish the phases of hemangioma during infancy and childhood J Clin Invest 93 2357 2364 (Pubitemid 24177146)
19. J Chang D Most S Bresnick B Mehrara DS Steinbrech J Reinisch MT Longaker AE Turk 1999 Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis Plast Reconstr Surg 103 1 9 (discussion 10)
20. A Picard E Boscolo ZA Khan TC Bartch JB Mulliken MP Vazquez J Bischoff 2008 IGF-2 and FLT-1/VEGF-R1 mRNA levels reveal distinctions and similarities between congenital and common infantile hemangioma Pediatr Res 63 263 267 (Pubitemid 351301454)
21. Y Yu J Varughese LF Brown JB Mulliken J Bischoff 2001 Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells Am J Pathol 159 2271 2280 (Pubitemid 33104280)
22. Y Yu AF Flint JB Mulliken JK Wu J Bischoff 2004 Endothelial progenitor cells in infantile hemangioma Blood 103 1373 1375 (Pubitemid 38168651)
23. PE North M Waner A Mizeracki RE Mrak R Nicholas J Kincannon JY Suen MC Mihm Jr 2001 A unique microvascular phenotype shared by juvenile hemangiomas and human placenta Arch Dermatol 137 559 570 (Pubitemid 32458438)
24. CM Barnes S Huang A Kaipainen D Sanoudou EJ Chen GS Eichler Y Guo Y Yu DE Ingber JB Mulliken 2005 Evidence by molecular profiling for a placental origin of infantile hemangioma Proc Natl Acad Sci USA 102 19097 19102 (Pubitemid 43049572)
25. CM Barnes EA Christison-Lagay J Folkman 2007 The placenta theory and the origin of infantile hemangioma Lymphat Res Biol 5 245 255
26. EI Chang EI Chang H Thangarajah C Hamou GC Gurtner 2007 Hypoxia, hormones, and endothelial progenitor cells in hemangioma Lymphat Res Biol 5 237 243
27. KM Pittman HW Losken ME Kleinman JR Marcus F Blei GC Gurtner DA Marchuk 2006 No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation J Invest Dermatol 126 2533 2538 (Pubitemid 44582274)
28. S Regnier N Dupin C Le Danff M Wassef O Enjolras S Aractingi 2007 Endothelial cells in infantile haemangiomas originate from the child and not from the mother (a fluorescence in situ hybridization-based study) Br J Dermatol 157 158 160 (Pubitemid 46934250)
29. CG Bauland MA van Steensel PM Steijlen PN Rieu PH Spauwen 2006 The pathogenesis of hemangiomas: a review Plast Reconstr Surg 117 29e 35e (Pubitemid 44400616)
30. GT Pack TR Miller 1950 Hemangiomas; classification, diagnosis and treatment Angiology 1 405 426
31. Virchow R (1863) Die Krankhaften Geschwulste. August Hirschwald, Berlin
32. G Pack 1950 Hemangiomas, classification, diagnosis, and treatment Angiology 1 40
33. Malan E (1974) Vascular Malformations (Angiodysplasias). Carlo Erba Foundation, Milan, p 4
34. JB Mulliken BR Zetter J Folkman 1982 In vitro characteristics of endothelium from hemangiomas and vascular malformations Surgery 92 348 353
35. A Dosanjh J Chang S Bresnick L Zhou J Reinisch M Longaker M Karasek 2000 In vitro characteristics of neonatal hemangioma endothelial cells: similarities and differences between normal neonatal and fetal endothelial cells J Cutan Pathol 27 441 450 (Pubitemid 30703217)
36. E Boye Y Yu G Paranya JB Mulliken BR Olsen J Bischoff 2001 Clonality and altered behavior of endothelial cells from hemangiomas J Clin Invest 107 745 752 (Pubitemid 32225360)
37. SS Dadras PE North J Bertoncini MC Mihm M Detmar 2004 Infantile hemangiomas are arrested in an early developmental vascular differentiation state Mod Pathol 17 1068 1079 (Pubitemid 39128233)
38. JW Walter PE North M Waner A Mizeracki F Blei JW Walker JF Reinisch DA Marchuk 2002 Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma Genes Chromosomes Cancer 33 295 303 (Pubitemid 34130936)
39. ZA Khan JM Melero-Martin X Wu S Paruchuri E Boscolo JB Mulliken J Bischoff 2006 Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin Blood 108 915 921 (Pubitemid 44154625)
40. MS O'Reilly T Boehm Y Shing N Fukai G Vasios WS Lane E Flynn JR Birkhead BR Olsen J Folkman 1997 Endostatin: an endogenous inhibitor of angiogenesis and tumor growth Cell 88 277 285 (Pubitemid 28015876)
41. ME Kleinman OM Tepper JM Capla KA Bhatt DJ Ceradini RD Galiano F Blei JP Levine GC Gurtner 2003 Increased circulating AC133+ CD34+ endothelial progenitor cells in children with hemangioma Lymphat Res Biol 1 301 307
42. U Ozerdem KA Grako K Dahlin-Huppe E Monosov WB Stallcup 2001 NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis Dev Dyn 222 218 227 (Pubitemid 32937594)
43. U Tigges EG Hyer J Scharf WB Stallcup 2008 FGF2-dependent neovascularization of subcutaneous Matrigel plugs is initiated by bone marrow-derived pericytes and macrophages Development 135 523 532
44. Q Li Y Yu J Bischoff JB Mulliken BR Olsen 2003 Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin J Pathol 201 296 302 (Pubitemid 37258941)
45. M Crisan S Yap L Casteilla CW Chen M Corselli TS Park G Andriolo B Sun B Zheng L Zhang 2008 A perivascular origin for mesenchymal stem cells in multiple human organs Cell Stem Cell 3 301 313
46. W Tang D Zeve JM Suh D Bosnakovski M Kyba RE Hammer MD Tallquist JM Graff 2008 White fat progenitor cells reside in the adipose vasculature Science 322 583 586
47. ZA Khan E Boscolo A Picard S Psutka JM Melero-Martin TC Bartch JB Mulliken J Bischoff 2008 Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice J Clin Invest 118 2592 2599 (Pubitemid 351949786)
48. MR Ritter MI Dorrell J Edmonds SF Friedlander M Friedlander 2002 Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis Proc Natl Acad Sci USA 99 7455 7460 (Pubitemid 34568712)
49. PE North M Waner A Mizeracki MC Mihm Jr 2000 GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas Hum Pathol 31 11 22 (Pubitemid 30054381)
50. JM Melero-Martin ME De Obaldia SY Kang ZA Khan L Yuan P Oettgen J Bischoff 2008 Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells Circ Res 103 194 202
51. F Loffredo RT Lee 2008 Therapeutic vasculogenesis: it takes two Circ Res 103 128 130
52. P Au J Tam D Fukumura RK Jain 2008 Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature Blood 111 4551 4558
53. ST Tan RA Wallis Y He PF Davis 2004 Mast cells and hemangioma Plast Reconstr Surg 113 999 1011 (Pubitemid 39195768)
54. KA Pasyk GW Cherry WC Grabb GH Sasaki 1984 Quantitative evaluation of mast cells in cellularly dynamic and adynamic vascular malformations Plast Reconstr Surg 73 69 77 (Pubitemid 14223361)
55. MR Ritter J Reinisch SF Friedlander M Friedlander 2006 Myeloid cells in infantile hemangioma Am J Pathol 168 621 628 (Pubitemid 43271159)
56. VA Nguyen C Furhapter N Romani F Weber N Sepp 2004 Infantile hemangioma is a proliferation of beta 4-negative endothelial cells adjacent to HLA-DR-positive cells with dendritic cell morphology Hum Pathol 35 739 744 (Pubitemid 38881085)
57. YC Jang FF Isik NS Gibran 2000 Nerve distribution in hemangiomas depends on the proliferative state of the microvasculature J Surg Res 93 144 148 (Pubitemid 30677332)
58. M Berard S Sordello N Ortega JL Carrier N Peyri M Wassef N Bertrand O Enjolras L Drouet J Plouet 1997 Vascular endothelial growth factor confers a growth advantage in vitro and in vivo to stromal cells cultured from neonatal hemangiomas Am J Pathol 150 1315 1326 (Pubitemid 27152650)
59. M Jinnin D Medici L Park N Limaye Y Liu E Boscolo J Bischoff M Vikkula E Boye BR Olsen 2008 Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma Nat Med 14 1236 1246
60. L Zhang X Lin W Wang X Zhuang J Dong Z Qi Q Hu 2005 Circulating level of vascular endothelial growth factor in differentiating hemangioma from vascular malformation patients Plast Reconstr Surg 116 200 204 (Pubitemid 40944039)
61. GH Fong J Rossant M Gertsenstein ML Breitman 1995 Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Nature 376 66 70
62. F Blei J Walter SJ Orlow DA Marchuk 1998 Familial segregation of hemangiomas and vascular malformations as an autosomal dominant trait Arch Dermatol 134 718 722 (Pubitemid 28283724)
63. JW Walter F Blei JL Anderson SJ Orlow MC Speer DA Marchuk 1999 Genetic mapping of a novel familial form of infantile hemangioma Am J Med Genet 82 77 83 (Pubitemid 29022304)
64. K Pramanik CZ Chun MK Garnaas GV Samant K Li MA Horswill PE North R Ramchandran 2009 Dusp-5 and Snrk-1 coordinately function during vascular development and disease Blood 113 1184 1191
65. F Qian F Zhen C Ong SW Jin H Meng Soo DY Stainier S Lin J Peng Z Wen 2005 Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes Dev Dyn 233 1163 1172 (Pubitemid 40853497)
66. S Sumanas T Jorniak S Lin 2005 Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants Blood 106 534 541 (Pubitemid 40981248)
67. B St Croix C Rago V Velculescu G Traverso KE Romans E Montgomery A Lal GJ Riggins C Lengauer B Vogelstein 2000 Genes expressed in human tumor endothelium Science 289 1197 1202 (Pubitemid 30650733)
68. JL Arbiser SW Weiss ZK Arbiser F Bravo B Govindajaran H Caceres-Rios G Cotsonis S Recavarren RA Swerlick C Cohen 2001 Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy J Am Acad Dermatol 44 193 197 (Pubitemid 32172179)
69. C Suri PF Jones S Patan S Bartunkova PC Maisonpierre S Davis TN Sato GD Yancopoulos 1996 Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis Cell 87 1171 1180 (Pubitemid 27010101)
70. PC Maisonpierre C Suri PF Jones S Bartunkova SJ Wiegand C Radziejewski D Compton J [tmp] McClain TH Aldrich N Papadopoulos 1997 Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis Science 277 55 60 (Pubitemid 27450643)
71. T Hawighorst M Skobe M Streit YK Hong P Velasco LF Brown L Riccardi B Lange-Asschenfeldt M Detmar 2002 Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth Am J Pathol 160 1381 1392 (Pubitemid 34411642)
72. O Stoeltzing SA Ahmad W Liu MF [tmp] McCarty AA Parikh F Fan N Reinmuth CD Bucana LM Ellis 2002 Angiopoietin-1 inhibits tumour growth and ascites formation in a murine model of peritoneal carcinomatosis Br J Cancer 87 1182 1187 (Pubitemid 35422722)
73. Y Feng F vom Hagen F Pfister S Djokic S Hoffmann W Back P Wagner J Lin U Deutsch HP Hammes 2007 Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression Thromb Haemost 97 99 108 (Pubitemid 46242391)
74. BN Perry B Govindarajan SS Bhandarkar UG Knaus M Valo C Sturk CO Carrillo A Sohn F Cerimele D Dumont 2006 Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice J Invest Dermatol 126 2316 2322 (Pubitemid 44413180)
75. JF Sun T Phung I Shiojima T Felske JN Upalakalin D Feng T Kornaga T Dor AM Dvorak K Walsh 2005 Microvascular patterning is controlled by fine-tuning the Akt signal Proc Natl Acad Sci USA 102 128 133 (Pubitemid 40094440)
76. TL Phung K Ziv D Dabydeen G Eyiah-Mensah M Riveros C Perruzzi J Sun RA Monahan-Earley I Shiojima JA Nagy 2006 Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Cancer Cell 10 159 170 (Pubitemid 44175906)
77. ME Kleinman MR Greives SS Churgin KM Blechman EI Chang DJ Ceradini OM Tepper GC Gurtner 2007 Hypoxia-induced mediators of stem/progenitor cell trafficking are increased in children with hemangioma Arterioscler Thromb Vasc Biol 27 2664 2670 (Pubitemid 350158920)
78. FF Isik RP Rand JS Gruss D Benjamin CE Alpers 1996 Monocyte chemoattractant protein-1 mRNA expression in hemangiomas and vascular malformations J Surg Res 61 71 76 (Pubitemid 26066031)
79. BM Kraling MJ Razon LM Boon D Zurakowski C Seachord RP Darveau JB Mulliken CL Corless J Bischoff 1996 E-selectin is present in proliferating endothelial cells in human hemangiomas Am J Pathol 148 1181 1191 (Pubitemid 26108255)
80. IY Oh CH Yoon J Hur JH Kim TY Kim CS Lee KW Park IH Chae BH Oh YB Park 2007 Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle Blood 110 3891 3899 (Pubitemid 350248444)
81. ME Gainers L Descheny SR Barthel L Liu MA Wurbel CJ Dimitroff 2007 Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis J Immunol 179 8509 8518
82. A Hidalgo LA Weiss PS Frenette 2002 Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally J Clin Invest 110 559 569 (Pubitemid 34919710)