Diabetes causes bone marrow endothelial barrier dysfunction by activation of the RhoA-rho-associated kinase signaling pathway

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 3, 2013, Pages 555-564

  Mangialardi, Giuseppe ^a   Katare, Rajesh ^a   Oikawa, Atsuhiko ^a   Meloni, Marco ^a   Reni, Carlotta ^a   Emanueli, Costanza ^a   Madeddu, Paolo ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

bone marrow; diabetic microangiopathy; endothelial dysfunction; oxidative stress; RhoA

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BIOLOGICAL MARKER; MECA32 PROTEIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL DEATH; CELL FUNCTION; CELLS; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GLUCOSE INTAKE; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; INTRACELLULAR SIGNALING; MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, SURFACE; BONE MARROW CELLS; CADHERINS; CAPILLARY PERMEABILITY; CELL MOVEMENT; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC ANGIOPATHIES; DRUG IMPLANTS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS; TRANSFECTION;

EID: 84874367540     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300424     Document Type: Article

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