-
1
-
-
56349142989
-
Bone remodelling: its local regulation and the emergence of bone fragility.
-
Martin TJ, Seeman E. Bone remodelling: its local regulation and the emergence of bone fragility. Best Pract Res Clin Endocrinol Metab 2008, 22:701-722.
-
(2008)
Best Pract Res Clin Endocrinol Metab
, vol.22
, pp. 701-722
-
-
Martin, T.J.1
Seeman, E.2
-
2
-
-
84879192402
-
Purinergic signalling in osteoblasts
-
in press.
-
Gartland A, Orriss IR, Rumney RMH, Bond AP, Arnett T, Gallagher JA. Purinergic signalling in osteoblasts Frontiers Biosci 2011, in press.
-
(2011)
Frontiers Biosci
-
-
Gartland, A.1
Orriss, I.R.2
Rumney, R.M.H.3
Bond, A.P.4
Arnett, T.5
Gallagher, J.A.6
-
3
-
-
80053125171
-
P2 receptor expression, signaling and function in osteoclasts.
-
Reyes JP, Sims SM, Dixon SJ. P2 receptor expression, signaling and function in osteoclasts. Front Biosci (Schol Ed) 2011, 3:1101-1118.
-
(2011)
Front Biosci (Schol Ed)
, vol.3
, pp. 1101-1118
-
-
Reyes, J.P.1
Sims, S.M.2
Dixon, S.J.3
-
4
-
-
0036788971
-
Molecular physiology of P2X receptors.
-
North RA. Molecular physiology of P2X receptors. Physiol Rev 2002, 82:1013-1067.
-
(2002)
Physiol Rev
, vol.82
, pp. 1013-1067
-
-
North, R.A.1
-
6
-
-
0034744672
-
Expression of a P2X(7) receptor by a subpopulation of human osteoblasts.
-
Gartland A, Hipskind RA, Gallagher JA, Bowler WB. Expression of a P2X(7) receptor by a subpopulation of human osteoblasts. J Bone Mineral Res 2001, 16:846-856.
-
(2001)
J Bone Mineral Res
, vol.16
, pp. 846-856
-
-
Gartland, A.1
Hipskind, R.A.2
Gallagher, J.A.3
Bowler, W.B.4
-
7
-
-
0032532942
-
Blockade of human P2X7 receptor function with a monoclonal antibody.
-
Buell G, Chessell IP, Michel AD, Collo G, Salazzo M, Herren S, Gretener D, Grahames C, Kaur R, Kosco-Vilbois MH, et al. Blockade of human P2X7 receptor function with a monoclonal antibody. Blood 1998, 92:3521-3528.
-
(1998)
Blood
, vol.92
, pp. 3521-3528
-
-
Buell, G.1
Chessell, I.P.2
Michel, A.D.3
Collo, G.4
Salazzo, M.5
Herren, S.6
Gretener, D.7
Grahames, C.8
Kaur, R.9
Kosco-Vilbois, M.H.10
-
8
-
-
44649092795
-
P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis.
-
Panupinthu N, Rogers JT, Zhao L, Solano-Flores LP, Possmayer F, Sims SM, Dixon SJ. P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis. J Cell Biol 2008, 181:859-871.
-
(2008)
J Cell Biol
, vol.181
, pp. 859-871
-
-
Panupinthu, N.1
Rogers, J.T.2
Zhao, L.3
Solano-Flores, L.P.4
Possmayer, F.5
Sims, S.M.6
Dixon, S.J.7
-
9
-
-
67650651202
-
Atypical P2X receptor pharmacology in two human osteoblast-like cell lines.
-
Alqallaf SM, Evans BA, Kidd EJ. Atypical P2X receptor pharmacology in two human osteoblast-like cell lines. Br J Pharmacol 2009, 156:1124-1135.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 1124-1135
-
-
Alqallaf, S.M.1
Evans, B.A.2
Kidd, E.J.3
-
10
-
-
67349186489
-
Expression, signaling, and function of P2X7 receptors in bone.
-
Grol MW, Panupinthu N, Korcok J, Sims SM, Dixon SJ. Expression, signaling, and function of P2X7 receptors in bone. Purinerg Signal 2009, 5:205-221.
-
(2009)
Purinerg Signal
, vol.5
, pp. 205-221
-
-
Grol, M.W.1
Panupinthu, N.2
Korcok, J.3
Sims, S.M.4
Dixon, S.J.5
-
11
-
-
0035914306
-
Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts.
-
Naemsch LN, Dixon SJ, Sims SM. Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts. J Biol Chem 2001, 276:39107-39114.
-
(2001)
J Biol Chem
, vol.276
, pp. 39107-39114
-
-
Naemsch, L.N.1
Dixon, S.J.2
Sims, S.M.3
-
12
-
-
0033805063
-
Expression of P2 receptors in bone and cultured bone cells.
-
Hoebertz A, Townsend-Nicholson A, Glass R, Burnstock G, Arnett TR. Expression of P2 receptors in bone and cultured bone cells. Bone 2000, 27:503-510.
-
(2000)
Bone
, vol.27
, pp. 503-510
-
-
Hoebertz, A.1
Townsend-Nicholson, A.2
Glass, R.3
Burnstock, G.4
Arnett, T.R.5
-
13
-
-
0036510537
-
Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors.
-
Jorgensen NR, Henriksen Z, Sorensen OH, Eriksen EF, Civitelli R, Steinberg TH. Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J Biol Chem 2002, 277:7574-7580.
-
(2002)
J Biol Chem
, vol.277
, pp. 7574-7580
-
-
Jorgensen, N.R.1
Henriksen, Z.2
Sorensen, O.H.3
Eriksen, E.F.4
Civitelli, R.5
Steinberg, T.H.6
-
14
-
-
0032711038
-
ATP receptors and giant cell formation.
-
Di Virgilio F, Falzoni S, Chiozzi P, Sanz JM, Ferrari D, Buell GN. ATP receptors and giant cell formation. J Leukoc Biol 1999, 66:723-726.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 723-726
-
-
Di Virgilio, F.1
Falzoni, S.2
Chiozzi, P.3
Sanz, J.M.4
Ferrari, D.5
Buell, G.N.6
-
15
-
-
0042047374
-
Blockade of the pore-forming P2X(7) receptor inhibits formation of multinucleated human osteoclasts in vitro.
-
Gartland A, Buckley KA, Bowler WB, Gallagher JA. Blockade of the pore-forming P2X(7) receptor inhibits formation of multinucleated human osteoclasts in vitro. Calcif Tissue Int 2003, 73:361-369.
-
(2003)
Calcif Tissue Int
, vol.73
, pp. 361-369
-
-
Gartland, A.1
Buckley, K.A.2
Bowler, W.B.3
Gallagher, J.A.4
-
16
-
-
25744479571
-
P2X(7) receptor-deficient mice maintain the ability to form multinucleated) osteoclasts in vivo and in vitro.
-
Gartland A, Buckley KA, Hipskind RA, Perry MJ, Tobias JH, Buell G, Chessel I, Bowler WB, Gallagher JA. P2X(7) receptor-deficient mice maintain the ability to form multinucleated) osteoclasts in vivo and in vitro. J Bone Mineral Res 2002, 17:P35.
-
(2002)
J Bone Mineral Res
, vol.17
-
-
Gartland, A.1
Buckley, K.A.2
Hipskind, R.A.3
Perry, M.J.4
Tobias, J.H.5
Buell, G.6
Chessel, I.7
Bowler, W.B.8
Gallagher, J.A.9
-
17
-
-
0037634326
-
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption.
-
Ke HZ, Qi H, Weidema AF, Zhang Q, Panupinthu N, Crawford DT, Grasser WA, Paralkar VM, Li M, Audoly LP, et al. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol 2003, 17:1356-1367.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1356-1367
-
-
Ke, H.Z.1
Qi, H.2
Weidema, A.F.3
Zhang, Q.4
Panupinthu, N.5
Crawford, D.T.6
Grasser, W.A.7
Paralkar, V.M.8
Li, M.9
Audoly, L.P.10
-
18
-
-
79954583662
-
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration.
-
Pellegatti P, Falzoni S, Donvito G, Lemaire I, Di Virgilio F. P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration. FASEB J 2011, 25:1264-1274.
-
(2011)
FASEB J
, vol.25
, pp. 1264-1274
-
-
Pellegatti, P.1
Falzoni, S.2
Donvito, G.3
Lemaire, I.4
Di Virgilio, F.5
-
19
-
-
77957303845
-
The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro.
-
Agrawal A, Buckley KA, Bowers K, Furber M, Gallagher JA, Gartland A. The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro. Purinerg Signal 6:307-315.
-
Purinerg Signal
, vol.6
, pp. 307-315
-
-
Agrawal, A.1
Buckley, K.A.2
Bowers, K.3
Furber, M.4
Gallagher, J.A.5
Gartland, A.6
-
20
-
-
50249159536
-
P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis.
-
Sharp AJ, Polak PE, Simonini V, Lin SX, Richardson JC, Bongarzone ER, Feinstein DL. P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis. J Neuroinf 2008, 5:33.
-
(2008)
J Neuroinf
, vol.5
, pp. 33
-
-
Sharp, A.J.1
Polak, P.E.2
Simonini, V.3
Lin, S.X.4
Richardson, J.C.5
Bongarzone, E.R.6
Feinstein, D.L.7
-
21
-
-
0037108511
-
Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.
-
Adriouch S, Dox C, Welge V, Seman M, Koch-Nolte F, Haag F. Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor. J Immunol 2002, 169:4108-4112.
-
(2002)
J Immunol
, vol.169
, pp. 4108-4112
-
-
Adriouch, S.1
Dox, C.2
Welge, V.3
Seman, M.4
Koch-Nolte, F.5
Haag, F.6
-
22
-
-
70350012258
-
A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice.
-
Nicke A, Kuan YH, Masin M, Rettinger J, Marquez-Klaka B, Bender O, Gorecki DC, Murrell-Lagnado RD, Soto F. A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice. J Biol Chem 2009, 284:25813-25822.
-
(2009)
J Biol Chem
, vol.284
, pp. 25813-25822
-
-
Nicke, A.1
Kuan, Y.H.2
Masin, M.3
Rettinger, J.4
Marquez-Klaka, B.5
Bender, O.6
Gorecki, D.C.7
Murrell-Lagnado, R.D.8
Soto, F.9
-
23
-
-
21244497838
-
Characterization of a functional P2X(7)-like receptor in cerebellar granule neurons from P2X(7) knockout mice.
-
Sanchez-Nogueiro J, Marin-Garcia P, Miras-Portugal MT. Characterization of a functional P2X(7)-like receptor in cerebellar granule neurons from P2X(7) knockout mice. FEBS Lett 2005, 579:3783-3788.
-
(2005)
FEBS Lett
, vol.579
, pp. 3783-3788
-
-
Sanchez-Nogueiro, J.1
Marin-Garcia, P.2
Miras-Portugal, M.T.3
-
24
-
-
84879192688
-
Bone status of P2X7 knockout mice in two different strains.
-
Syberg S, Schwarz P, Petersen S, Jensen JEB, Steinberg TH, Gartland A, Chessell I, Jorgensen NR. Bone status of P2X7 knockout mice in two different strains. Purinerg Signal 2010, 6:158.
-
(2010)
Purinerg Signal
, vol.6
, pp. 158
-
-
Syberg, S.1
Schwarz, P.2
Petersen, S.3
Jensen, J.E.B.4
Steinberg, T.H.5
Gartland, A.6
Chessell, I.7
Jorgensen, N.R.8
-
25
-
-
30044443068
-
The P2X7 nucleotide receptor mediates skeletal mechanotransduction.
-
Li J, Liu D, Ke HZ, Duncan RL, Turner CH. The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem 2005, 280:42952-42959.
-
(2005)
J Biol Chem
, vol.280
, pp. 42952-42959
-
-
Li, J.1
Liu, D.2
Ke, H.Z.3
Duncan, R.L.4
Turner, C.H.5
-
26
-
-
84879192122
-
The purinergic P2X(7) receptor is responsible for ovariectomy-induced bone loss in mice.
-
Petersen S, Syberg S, Henriksen Z, Schwarz P, Jensen JB, Sorensen OH, Jorgensen NR. The purinergic P2X(7) receptor is responsible for ovariectomy-induced bone loss in mice. J Bone Mineral Res 2007, 22:S108.
-
(2007)
J Bone Mineral Res
, vol.22
-
-
Petersen, S.1
Syberg, S.2
Henriksen, Z.3
Schwarz, P.4
Jensen, J.B.5
Sorensen, O.H.6
Jorgensen, N.R.7
-
27
-
-
84879194504
-
P2X(7) agonist reduce ovariectomy-induced bone loss in a murine model.
-
Syberg S, Petersen S, Teilmann J, Jensen JB, Schwarz P, Jorgensen NR. P2X(7) agonist reduce ovariectomy-induced bone loss in a murine model. J Bone Mineral Res 2007, 22:S448.
-
(2007)
J Bone Mineral Res
, vol.22
-
-
Syberg, S.1
Petersen, S.2
Teilmann, J.3
Jensen, J.B.4
Schwarz, P.5
Jorgensen, N.R.6
-
28
-
-
34250210564
-
Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment.
-
Ohlendorff SD, Tofteng CL, Jensen JE, Petersen S, Civitelli R, Fenger M, Abrahamsen B, Hermann AP, Eiken P, Jorgensen NR. Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment. Pharmacogenet Genom 2007, 17:555-567.
-
(2007)
Pharmacogenet Genom
, vol.17
, pp. 555-567
-
-
Ohlendorff, S.D.1
Tofteng, C.L.2
Jensen, J.E.3
Petersen, S.4
Civitelli, R.5
Fenger, M.6
Abrahamsen, B.7
Hermann, A.P.8
Eiken, P.9
Jorgensen, N.R.10
-
29
-
-
79952775453
-
Loss of function polymorphisms in the P2X(7) receptor gene are associated with accelerated lumbar spine bone loss in postmenopausal women.
-
Gartland A, Skarratt KK, Hocking LJ, Stokes L, Clifton-Bligh R, Parsons C, Fraser WD, Reid DM, Wiley JS, Gallagher JA. Loss of function polymorphisms in the P2X(7) receptor gene are associated with accelerated lumbar spine bone loss in postmenopausal women. J Bone Mineral Res 2008, 23:S296.
-
(2008)
J Bone Mineral Res
, vol.23
-
-
Gartland, A.1
Skarratt, K.K.2
Hocking, L.J.3
Stokes, L.4
Clifton-Bligh, R.5
Parsons, C.6
Fraser, W.D.7
Reid, D.M.8
Wiley, J.S.9
Gallagher, J.A.10
-
30
-
-
74449083980
-
Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty: a preliminary study.
-
Mrazek F, Gallo J, Stahelova A, Petrek M. Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty: a preliminary study. Hum Immunol 2010, 71:201-205.
-
(2010)
Hum Immunol
, vol.71
, pp. 201-205
-
-
Mrazek, F.1
Gallo, J.2
Stahelova, A.3
Petrek, M.4
-
31
-
-
0033491119
-
P2X(4) purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts.
-
Naemsch LN, Weidema AF, Sims SM, Underhill TM, Dixon SJ. P2X(4) purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts. J Cell Sci 1999, 112((Pt 23)):4425-4435.
-
(1999)
J Cell Sci
, vol.112
, Issue.PART 23
, pp. 4425-4435
-
-
Naemsch, L.N.1
Weidema, A.F.2
Sims, S.M.3
Underhill, T.M.4
Dixon, S.J.5
-
32
-
-
0034979213
-
Activation of P2Y but not P2X(4) nucleotide receptors causes elevation of [Ca2+]i in mammalian osteoclasts.
-
Weidema AF, Dixon SJ, Sims SM. Activation of P2Y but not P2X(4) nucleotide receptors causes elevation of [Ca2+]i in mammalian osteoclasts. Am J Physiol Cell Physiol 2001, 280:C1531-C1539.
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Weidema, A.F.1
Dixon, S.J.2
Sims, S.M.3
-
33
-
-
0033851335
-
ATP activates DNA synthesis by acting on P2X receptors in human osteoblast-like MG-63 cells.
-
Nakamura E, Uezono Y, Narusawa K, Shibuya I, Oishi Y, Tanaka M, Yanagihara N, Nakamura T, Izumi F. ATP activates DNA synthesis by acting on P2X receptors in human osteoblast-like MG-63 cells. Am J Physiol Cell Physiol 2000, 279:C510-C519.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Nakamura, E.1
Uezono, Y.2
Narusawa, K.3
Shibuya, I.4
Oishi, Y.5
Tanaka, M.6
Yanagihara, N.7
Nakamura, T.8
Izumi, F.9
-
34
-
-
33744908812
-
Osteoblast responses to nucleotides increase during differentiation.
-
Orriss IR, Knight GE, Ranasinghe S, Burnstock G, Arnett TR. Osteoblast responses to nucleotides increase during differentiation. Bone 2006, 39:300-309.
-
(2006)
Bone
, vol.39
, pp. 300-309
-
-
Orriss, I.R.1
Knight, G.E.2
Ranasinghe, S.3
Burnstock, G.4
Arnett, T.R.5
-
35
-
-
0036212603
-
A rat model of bone cancer pain.
-
Medhurst SJ, Walker K, Bowes M, Kidd BL, Glatt M, Muller M, Hattenberger M, Vaxelaire J, O'Reilly T, Wotherspoon G, et al. A rat model of bone cancer pain. Pain 2002, 96:129-140.
-
(2002)
Pain
, vol.96
, pp. 129-140
-
-
Medhurst, S.J.1
Walker, K.2
Bowes, M.3
Kidd, B.L.4
Glatt, M.5
Muller, M.6
Hattenberger, M.7
Vaxelaire, J.8
O'Reilly, T.9
Wotherspoon, G.10
-
36
-
-
47549090957
-
Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X(2/3) receptor function and exerts an analgesic effect in pain models.
-
Kakimoto S, Nagakura Y, Tamura S, Watabiki T, Shibasaki K, Tanaka S, Mori M, Sasamata M, Okada M. Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X(2/3) receptor function and exerts an analgesic effect in pain models. Eur J Pharmacol 2008, 589:98-101.
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 98-101
-
-
Kakimoto, S.1
Nagakura, Y.2
Tamura, S.3
Watabiki, T.4
Shibasaki, K.5
Tanaka, S.6
Mori, M.7
Sasamata, M.8
Okada, M.9
-
37
-
-
84879191588
-
-
Further reading has been suggested throughout the text; for readers wanting an overview of bone physiology, current discoveries and developments in the area of bone are encouraged to visit the website of the international and national bone research societies: American Society for Bone and Mineral research (); International Bone and Mineral Society () and the European Calcified Tissue Society ().
-
Further reading has been suggested throughout the text; for readers wanting an overview of bone physiology, current discoveries and developments in the area of bone are encouraged to visit the website of the international and national bone research societies: American Society for Bone and Mineral research (http://www.asbmr.org); International Bone and Mineral Society (http://www.ibmsonline.org/) and the European Calcified Tissue Society (http://www.ectsoc.org/).
-
-
-
|