Characterization of a functional P2X7-like receptor in cerebellar granule neurons from P2X7 knockout mice

FEBS Letters

Volumn 579, Issue 17, 2005, Pages 3783-3788

  Sánchez Nogueiro, Jesús ^a   Marín García, Patricia ^a   Miras Portugal, M Teresa ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

2 3 O (4 Benzoylbenzoyl) adenosine 5 triphosphate; Adenosine 5 triphosphate; Calcium imaging; Central nervous system; Knockout mice; P2X7 receptor

Indexed keywords

CALCIUM ION; EPITOPE; MESSENGER RNA; PURINE P2X7 LIKE RECEPTOR; PURINE P2X7 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MALE; MOUSE; NERVE CELL; NERVE CELL CULTURE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; CEREBELLUM; MICE; MICE, KNOCKOUT; NEURONS; RECEPTORS, PURINERGIC P2; RNA, MESSENGER;

ANIMALIA; EPICOCCUM;

EID: 21244497838     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.05.073     Document Type: Article

References (26)

1. R.A. North Molecular physiology of P2X receptors Physiol. Rev. 82 2002 1013 1067
2. P. Illes, and J.A. Ribeiro Molecular physiology of P2 receptors in the central nervous system Eur. J. Pharmacol. 483 2004 5 17
3. B.S. Khakh, G. Burnstock, C. Kennedy, B.F. King, R.A. North, P. Seguela, M. Voigt, and P.P. Humphrey International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits Pharmacol. Rev. 53 2001 107 118
4. R.A. North, and A. Surprenant Pharmacology of cloned P2X receptors Ann. Rev. Pharmacol. Toxicol. 40 2000 563 580
5. G.E. Torres, T.M. Egan, and M.M. Voigt Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners J. Biol. Chem. 274 1999 6653 6659
6. 7 receptors J. Biol. Chem. 276 2001 125 132
7. 7 receptor J. Biol. Chem. 278 2003 17108 17113
8. 7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems J. Neurosci. 21 2001 7143 7152
9. 7 receptors in rat brain: presence in synaptic terminals and granule cells Neurochem. Res. 28 2003 1597 1605
10. 7 receptor immunoreactivity in distinct subsets of synaptic terminals in the ventral horn of rat lumbar spinal cord Brain Res. 1020 2004 53 61
11. C. Hervás, R. Pérez-Sen, and M.T. Miras-Portugal Coexpression of functional P2X and P2Y nucleotide receptors in single cerebellar granule cells J. Neurosci. Res. 73 2003 384 399
12. 7 receptor agonist 2′-3′-O-(4-benzoylbenzoyl)-ATP J. Neurosci. 24 2004 7128 7139
13. - mice Neuroreport 15 2004 2387 2391
14. 7 receptor expression in rodent brain J. Neurosci. 24 2004 6307 6314
15. P.R. Dunkley, P.E. Jarvie, J.W. Heath, G.J. Kidd, and J.A. Rostas A rapid method for isolation of synaptosomes on Percoll gradients Brain Res. 372 1986 115 129
16. V. Gallo, A. Kingsbury, R. Balazs, and O.S. Jorgensen The role of depolarization in the survival and differentiation of cerebellar granule cells in culture J. Neurosci. 7 1987 2203 2213
17. J.R. Luque-Ortega, S. Martínez, J.M. Saugar, L.R. Izquierdo, T. Abad, G.J. Luis, J. Piñero, B. Valladares, and L. Rivas Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria of Leishmania donovani promastigotes Antimicrob. Agents Chemother. 48 2004 1534 1540
18. 3 subunits Neurosci. Lett. 301 2001 159 162
19. 2+ indicators with greatly improved fluorescence properties J. Biol. Chem. 260 1985 3440 3450
20. M. Díaz-Hernández, J. Pintor, E. Castro, and M.T. Miras-Portugal Independent receptors for diadenosine pentaphosphate and ATP in rat midbrain single synaptic terminals Eur. J. Neurosci. 14 2001 918 926
21. 7 receptor Neuropharmacology 36 1997 1285 1294
22. 7 receptor alters leukocyte function and attenuates an inflammatory response J. Immunol. 168 2002 6436 6445
23. 7 nucleotide receptor reveals its regulatory roles in bone formation and resorption Mol. Endocrinol. 17 2003 1356 1367
24. 7 receptors in submandibular ductal cells Cell. Signal. 15 2003 927 935
25. 7. XXVII Congreso de la SEBBM.
26. Hervás, C., Pérez-Sen, R., Miras-Portugal, M.T., (2005). Presence of diverse functional P2X receptors in rat cerebellar synaptic terminals. Biochem. Pharmacol., in press.