-
1
-
-
73649170794
-
The treatment of chronic ulcerative colitis with 6-mercaptopurine
-
Bean RH. The treatment of chronic ulcerative colitis with 6-mercaptopurine. Med J Aust 1962; 49: 592-593.
-
(1962)
Med J Aust
, vol.49
, pp. 592-593
-
-
Bean, R.H.1
-
2
-
-
0014685582
-
Azathioprine for Crohn's disease
-
Brooke B. Azathioprine for Crohn's disease. Lancet 1969; 294: 612-614.
-
(1969)
Lancet
, vol.294
, pp. 612-614
-
-
Brooke, B.1
-
3
-
-
27744461917
-
Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
-
Gearry RB, Barclay ML. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. J Gastroenterol Hepatol 2005; 20: 1149-1157.
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 1149-1157
-
-
Gearry, R.B.1
Barclay, M.L.2
-
4
-
-
75149161836
-
The second European evidence-based consensus on the diagnosis and management of Crohn's disease: current management
-
Dignass A, Van Assche G, Lindsay JO, Lémann M, Söderholm J, Colombel JF et al. The second European evidence-based consensus on the diagnosis and management of Crohn's disease: current management. J Crohns Colitis 2010; 4: 28-62.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 28-62
-
-
Dignass, A.1
Van Assche, G.2
Lindsay, J.O.3
Lémann, M.4
Söderholm, J.5
Colombel, J.F.6
-
5
-
-
79953761841
-
Guidelines for the management of inflammatory bowel disease in adults
-
Mowat C, Cole A, Windsor A, Ahmad T, Arnott I, Driscoll R et al. Guidelines for the management of inflammatory bowel disease in adults. Gut 2011; 60: 571-607.
-
(2011)
Gut
, vol.60
, pp. 571-607
-
-
Mowat, C.1
Cole, A.2
Windsor, A.3
Ahmad, T.4
Arnott, I.5
Driscoll, R.6
-
6
-
-
38749095183
-
European evidence-based consensus on the management of ulcerative colitis: current management
-
Travis SPL, Stange EF, Lémann M, Oresland T, Bemelman WA, Chowers Y et al. European evidence-based consensus on the management of ulcerative colitis: current management. J Crohns Colitis 2008; 2: 24-62.
-
(2008)
J Crohns Colitis
, vol.2
, pp. 24-62
-
-
Travis, S.P.L.1
Stange, E.F.2
Lémann, M.3
Oresland, T.4
Bemelman, W.A.5
Chowers, Y.6
-
7
-
-
0029953165
-
Should 6-thioguanine nucleotides be monitored in heart transplant recipients given azathioprine?
-
Schütz E, Gummert J, Mohr FW, Armstrong VW, Oellerich M. Should 6-thioguanine nucleotides be monitored in heart transplant recipients given azathioprine? Ther Drug Monit 1996; 18: 228-233.
-
(1996)
Ther Drug Monit
, vol.18
, pp. 228-233
-
-
Schütz, E.1
Gummert, J.2
Mohr, F.W.3
Armstrong, V.W.4
Oellerich, M.5
-
8
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, Théorêt Y et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000; 118: 705-713.
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
Targan, S.R.4
Sinnett, D.5
Théorêt, Y.6
-
9
-
-
56749185267
-
Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides
-
Gardiner SJ, Gearry RB, Burt MJ, Ding SL, Barclay ML. Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides. Eur J Gastroenterol Hepatol 2008; 20: 1238-1242.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 1238-1242
-
-
Gardiner, S.J.1
Gearry, R.B.2
Burt, M.J.3
Ding, S.L.4
Barclay, M.L.5
-
10
-
-
3543150184
-
Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease
-
Achkar J-P, Stevens T, Easley K, Brzezinski A, Seidner D, Lashner B. Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease. Inflamm Bowel Dis 2004; 10: 339-345.
-
(2004)
Inflamm Bowel Dis
, vol.10
, pp. 339-345
-
-
Achkar, J.-P.1
Stevens, T.2
Easley, K.3
Brzezinski, A.4
Seidner, D.5
Lashner, B.6
-
11
-
-
4544294487
-
The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease
-
Goldenberg BA, Rawsthorne P, Bernstein CN. The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease. Am J Gastroenterol 2004; 99: 1744-1748.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1744-1748
-
-
Goldenberg, B.A.1
Rawsthorne, P.2
Bernstein, C.N.3
-
12
-
-
8844267645
-
Monitoring of long-term thiopurine therapy among adults with inflammatory bowel disease
-
Hindorf U, Lyrenäs E, Nilsson A, Schmiegelow K. Monitoring of long-term thiopurine therapy among adults with inflammatory bowel disease. Scand J Gastroenterol 2004; 39: 1105-1112.
-
(2004)
Scand J Gastroenterol
, vol.39
, pp. 1105-1112
-
-
Hindorf, U.1
Lyrenäs, E.2
Nilsson, A.3
Schmiegelow, K.4
-
13
-
-
0035134907
-
Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease
-
Belaiche J, Desager JP, Horsmans Y, Louis E. Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease. Scand J Gastroenterol 2001; 36: 71-76.
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 71-76
-
-
Belaiche, J.1
Desager, J.P.2
Horsmans, Y.3
Louis, E.4
-
14
-
-
3242732900
-
Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease
-
Wright S, Sanders DS, Lobo AJ, Lennard L. Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease. Gut 2004; 53: 1123-1128.
-
(2004)
Gut
, vol.53
, pp. 1123-1128
-
-
Wright, S.1
Sanders, D.S.2
Lobo, A.J.3
Lennard, L.4
-
15
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, Abreu MT et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002; 122: 904-915.
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.2
Hassard, P.V.3
Seidman, E.G.4
Kam, L.Y.5
Abreu, M.T.6
-
16
-
-
0034771188
-
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
-
Lowry PW, Franklin CL, Weaver AL, Pike MG, Mays DC, Tremaine WJ et al. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 2001; 49: 665-670.
-
(2001)
Gut
, vol.49
, pp. 665-670
-
-
Lowry, P.W.1
Franklin, C.L.2
Weaver, A.L.3
Pike, M.G.4
Mays, D.C.5
Tremaine, W.J.6
-
17
-
-
33646011261
-
Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis
-
Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 2006; 130: 1047-1053.
-
(2006)
Gastroenterology
, vol.130
, pp. 1047-1053
-
-
Osterman, M.T.1
Kundu, R.2
Lichtenstein, G.R.3
Lewis, J.D.4
-
18
-
-
77958151454
-
Usefulness of the measurement of azathioprine metabolites in the assessment of non-adherence
-
Stocco G, Londero M, Campanozzi A, Martelossi S, Marino S, Malusa N et al. Usefulness of the measurement of azathioprine metabolites in the assessment of non-adherence. J Crohns Colitis 2010; 4: 599-602.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 599-602
-
-
Stocco, G.1
Londero, M.2
Campanozzi, A.3
Martelossi, S.4
Marino, S.5
Malusa, N.6
-
19
-
-
24344480999
-
Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine
-
Sparrow MP, Hande SA, Friedman S, Lim WC, Reddy SI, Cao D et al. Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. Aliment Pharmacol Ther 2005; 22: 441-446.
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 441-446
-
-
Sparrow, M.P.1
Hande, S.A.2
Friedman, S.3
Lim, W.C.4
Reddy, S.I.5
Cao, D.6
-
20
-
-
78649710356
-
Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio
-
Gardiner SJ, Gearry RB, Burt MJ, Chalmers-Watson T, Chapman BA, Ross AG et al. Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio. J Gastroenterol Hepatol 2011; 26: 49-54.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 49-54
-
-
Gardiner, S.J.1
Gearry, R.B.2
Burt, M.J.3
Chalmers-Watson, T.4
Chapman, B.A.5
Ross, A.G.6
-
21
-
-
77955462122
-
IBD: switching metabolism - can two drugs be better than one?
-
Sparrow MP. IBD: switching metabolism - can two drugs be better than one? Nat Rev Gastroenterol Hepatol 2010; 7: 420-422.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 420-422
-
-
Sparrow, M.P.1
-
22
-
-
54449088799
-
Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol
-
Leong RW, Gearry RB, Sparrow MP. Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol. Expert Opin Drug Saf 2008; 7: 607-616.
-
(2008)
Expert Opin Drug Saf
, vol.7
, pp. 607-616
-
-
Leong, R.W.1
Gearry, R.B.2
Sparrow, M.P.3
-
23
-
-
76449085161
-
Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease
-
Ansari A, Patel N, Sanderson J, O'Donohue J, Duley JA, Florin THJ. Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2010; 31: 640-647.
-
(2010)
Aliment Pharmacol Ther
, vol.31
, pp. 640-647
-
-
Ansari, A.1
Patel, N.2
Sanderson, J.3
O'Donohue, J.4
Duley, J.A.5
Florin, T.H.J.6
-
24
-
-
49849088177
-
Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease
-
Ansari A, Elliott T, Baburajan B, Mayhead P, O'Donohue J, Chocair P et al. Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease. Aliment Pharmacol Ther 2008; 28: 734-741.
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 734-741
-
-
Ansari, A.1
Elliott, T.2
Baburajan, B.3
Mayhead, P.4
O'Donohue, J.5
Chocair, P.6
-
25
-
-
42449087386
-
Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature
-
Witte TN, Ginsberg AL. Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature. Can J Gastroenterol 2008; 22: 181-185.
-
(2008)
Can J Gastroenterol
, vol.22
, pp. 181-185
-
-
Witte, T.N.1
Ginsberg, A.L.2
-
26
-
-
77958152828
-
A prospective evaluation of the impact of allopurinol in pediatric and adult IBD patients with preferential metabolism of 6-mercaptopurine to 6-methylmercaptopurine
-
Gerich ME, Quiros JA, Marcin JP, Tennyson L, Henthorn M, Prindiville TP. A prospective evaluation of the impact of allopurinol in pediatric and adult IBD patients with preferential metabolism of 6-mercaptopurine to 6-methylmercaptopurine. J Crohns Colitis 2010; 4: 546-552.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 546-552
-
-
Gerich, M.E.1
Quiros, J.A.2
Marcin, J.P.3
Tennyson, L.4
Henthorn, M.5
Prindiville, T.P.6
-
27
-
-
67651083623
-
Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease
-
Leung Y, Sparrow MP, Schwartz M, Hanauer SB. Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease. J Crohns Colitis 2009; 3: 162-167.
-
(2009)
J Crohns Colitis
, vol.3
, pp. 162-167
-
-
Leung, Y.1
Sparrow, M.P.2
Schwartz, M.3
Hanauer, S.B.4
-
28
-
-
52149089035
-
Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease
-
Rahhal RM, Bishop WP. Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease. Inflamm Bowel Dis 2008; 14: 1678-1682.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1678-1682
-
-
Rahhal, R.M.1
Bishop, W.P.2
-
29
-
-
27644565720
-
Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice
-
Gearry RB, Barclay ML, Roberts RL, Harraway J, Zhang M, Pike LS et al. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice. Intern Med J 2005; 35: 580-585.
-
(2005)
Intern Med J
, vol.35
, pp. 580-585
-
-
Gearry, R.B.1
Barclay, M.L.2
Roberts, R.L.3
Harraway, J.4
Zhang, M.5
Pike, L.S.6
-
30
-
-
79955828365
-
Clinical usefulness of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease
-
Haines ML, Ajlouni Y, Irving PM, Sparrow MP, Rose R, Gearry RB et al. Clinical usefulness of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease. Inflamm Bowel Dis 2011; 17: 1301-1307.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1301-1307
-
-
Haines, M.L.1
Ajlouni, Y.2
Irving, P.M.3
Sparrow, M.P.4
Rose, R.5
Gearry, R.B.6
-
31
-
-
80052902189
-
Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: a worldwide survey of experts
-
Roblin X, Oussalah A, Chevaux J-B, Sparrow M, Peyrin-Biroulet L. Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: a worldwide survey of experts. Inflamm Bowel Dis 2011; 17: 2480-2487.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 2480-2487
-
-
Roblin, X.1
Oussalah, A.2
Chevaux, J.-B.3
Sparrow, M.4
Peyrin-Biroulet, L.5
-
32
-
-
84863320682
-
Azathioprine, 6-mercaptopurine and thiopurine s-methyltransferase levels in inflammatory bowel disease: what is current clinical practice?
-
Siriwardana A, Koo J, Ng W, Connor S. Azathioprine, 6-mercaptopurine and thiopurine s-methyltransferase levels in inflammatory bowel disease: what is current clinical practice? J Gastroenterol Hepatol 2009; 24(s2): A311-312.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, Issue.S2
-
-
Siriwardana, A.1
Koo, J.2
Ng, W.3
Connor, S.4
-
33
-
-
79961209172
-
Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients
-
González-Lama Y, Bermejo F, López-Sanromán A, García-Sánchez V, Esteve M, Cabriada JL et al. Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients. Aliment Pharmacol Ther 2011; 34: 544-554.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 544-554
-
-
González-Lama, Y.1
Bermejo, F.2
López-Sanromán, A.3
García-Sánchez, V.4
Esteve, M.5
Cabriada, J.L.6
-
34
-
-
77950172740
-
Azathioprine and allopurinol: a two-edged interaction
-
Gearry RB, Day AS, Barclay ML, Leong RWL, Sparrow MP. Azathioprine and allopurinol: a two-edged interaction. J Gastroenterol Hepatol 2010; 25: 653-655.
-
(2010)
J Gastroenterol Hepatol
, vol.25
, pp. 653-655
-
-
Gearry, R.B.1
Day, A.S.2
Barclay, M.L.3
Leong, R.W.L.4
Sparrow, M.P.5
-
35
-
-
79955568740
-
T1192 a randomized trial of metabolite-adjusted versus weight-based dosing of azathioprine (AZA) in Crohn's disease (CD)
-
clinicaltrials.Gov identifier Nct00113503
-
Dassopoulos T, Martin CF, Galanko J, Wolf DC, Dubinsky M, Sandler RS et al. T1192 a randomized trial of metabolite-adjusted versus weight-based dosing of azathioprine (AZA) in Crohn's disease (CD). [clinicaltrials.Gov identifier Nct00113503]. Gastroenterology 2009; 136: A-519.
-
(2009)
Gastroenterology
, vol.136
-
-
Dassopoulos, T.1
Martin, C.F.2
Galanko, J.3
Wolf, D.C.4
Dubinsky, M.5
Sandler, R.S.6
-
36
-
-
71149092879
-
Characterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitis
-
Hindorf U, Jahed K, Bergquist A, Verbaan H, Prytz H, Wallerstedt S et al. Characterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitis. J Hepatol 2010; 52: 106-111.
-
(2010)
J Hepatol
, vol.52
, pp. 106-111
-
-
Hindorf, U.1
Jahed, K.2
Bergquist, A.3
Verbaan, H.4
Prytz, H.5
Wallerstedt, S.6
-
37
-
-
11144239008
-
Non-adherence to medications following pediatric liver transplantation
-
Shemesh E. Non-adherence to medications following pediatric liver transplantation. Pediatr Transplant 2004; 8: 600-605.
-
(2004)
Pediatr Transplant
, vol.8
, pp. 600-605
-
-
Shemesh, E.1
-
38
-
-
67449138845
-
Thioguanine nucleotides and thiopurine methyltransferase in immunobullous diseases: optimal levels as adjunctive tools for azathioprine monitoring
-
El-Azhary RA, Farmer SA, Drage LA, Rogers RS, McEvoy MT, Davis MDP et al. Thioguanine nucleotides and thiopurine methyltransferase in immunobullous diseases: optimal levels as adjunctive tools for azathioprine monitoring. Arch Dermatol 2009; 145: 644-652.
-
(2009)
Arch Dermatol
, vol.145
, pp. 644-652
-
-
El-Azhary, R.A.1
Farmer, S.A.2
Drage, L.A.3
Rogers, R.S.4
McEvoy, M.T.5
Davis, M.D.P.6
-
39
-
-
58149517583
-
Use of pharmacogenetics, enzymatic phenotyping, and metabolite monitoring to guide treatment with azathioprine in patients with systemic lupus erythematosus
-
Askanase AD, Wallace DJ, Weisman MH, Tseng C-E, Bernstein L, Belmont HM et al. Use of pharmacogenetics, enzymatic phenotyping, and metabolite monitoring to guide treatment with azathioprine in patients with systemic lupus erythematosus. J Rheumatol 2009; 36: 89-95.
-
(2009)
J Rheumatol
, vol.36
, pp. 89-95
-
-
Askanase, A.D.1
Wallace, D.J.2
Weisman, M.H.3
Tseng, C.-E.4
Bernstein, L.5
Belmont, H.M.6
|