-
1
-
-
0033934903
-
Immunosuppression: Back to the future
-
Schwartz RS. Immunosuppression: back to the future. World J Surg. 2000;24(7):783-786.
-
(2000)
World J Surg
, vol.24
, Issue.7
, pp. 783-786
-
-
Schwartz, R.S.1
-
2
-
-
0037529212
-
Azathioprine: Current status and future considerations
-
El-Azhary RA. Azathioprine: current status and future considerations. Int J Dermatol. 2003;42(5):335-341.
-
(2003)
Int J Dermatol
, vol.42
, Issue.5
, pp. 335-341
-
-
El-Azhary, R.A.1
-
3
-
-
0000742451
-
Basic biochemical effects and mechanism of action of 6-thioguanine
-
Lepage GA. Basic biochemical effects and mechanism of action of 6-thioguanine. Cancer Res. 1963;23:1202-1206.
-
(1963)
Cancer Res
, vol.23
, pp. 1202-1206
-
-
Lepage, G.A.1
-
4
-
-
0027239758
-
The George Hitchings and Gertrude Elion lecture: The pharmacology of azathioprine
-
Elion GB. The George Hitchings and Gertrude Elion lecture: the pharmacology of azathioprine. Ann N Y Acad Sci. 1993;685:400-407.
-
(1993)
Ann N Y Acad Sci
, vol.685
, pp. 400-407
-
-
Elion, G.B.1
-
5
-
-
0038326642
-
Differential control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and pyrimidine nucleotides
-
Quéméneur L, Gerland LM, Flacher M, Ffrench M, Revillard JP, Genestier L. Differential control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and pyrimidine nucleotides. J Immunol. 2003;170(10):4986-4995. (Pubitemid 36554728)
-
(2003)
Journal of Immunology
, vol.170
, Issue.10
, pp. 4986-4995
-
-
Quemeneur, L.1
Gerland, L.-M.2
Flacher, M.3
Ffrench, M.4
Revillard, J.-P.5
Genestier, L.6
-
7
-
-
0020534019
-
Variable bioavailability of oral mercaptopurine: Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?
-
Zimm S, Collins JM, Riccardi R, et al. Variable bioavailability of oral mercaptopurine: is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered? N Engl J Med. 1983;308(17):1005-1009.
-
(1983)
N Engl J Med
, vol.308
, Issue.17
, pp. 1005-1009
-
-
Zimm, S.1
Collins, J.M.2
Riccardi, R.3
-
8
-
-
0029975534
-
Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration
-
Van Os EC, Zins BJ, Sandborn WJ, et al. Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration. Gut. 1996;39(1):63-68. (Pubitemid 26239107)
-
(1996)
Gut
, vol.39
, Issue.1
, pp. 63-68
-
-
Van Os, E.C.1
Zins, B.J.2
Sandborn, W.J.3
Mays, D.C.4
Tremaine, W.J.5
Mahoney, D.W.6
Zinsmeister, A.R.7
Lipsky, J.J.8
-
9
-
-
0028843101
-
The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients
-
Snow JL, Gibson LE. The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients. Arch Dermatol. 1995;131(2):193-197.
-
(1995)
Arch Dermatol
, vol.131
, Issue.2
, pp. 193-197
-
-
Snow, J.L.1
Gibson, L.E.2
-
10
-
-
0028891465
-
A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients
-
Snow JL, Gibson LE. A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients. J Am Acad Dermatol. 1995;32(1):114-116.
-
(1995)
J Am Acad Dermatol
, vol.32
, Issue.1
, pp. 114-116
-
-
Snow, J.L.1
Gibson, L.E.2
-
11
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet. 1980;32(5):651-662. (Pubitemid 10061685)
-
(1980)
American Journal of Human Genetics
, vol.32
, Issue.5
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
12
-
-
0032231751
-
Pharmacogenetics of cancer therapy: Getting personal
-
DOI 10.1086/301941
-
Krynetski EY, Evans WE. Pharmacogenetics of cancer therapy: getting personal. Am J Hum Genet. 1998;63(1):11-16. (Pubitemid 30428311)
-
(1998)
American Journal of Human Genetics
, vol.63
, Issue.1
, pp. 11-16
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
13
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
-
Relling MV, Hancock ML, Rivera GK, et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst. 1999;91(23):2001-2008.
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.23
, pp. 2001-2008
-
-
Relling, M.V.1
Hancock, M.L.2
Rivera, G.K.3
-
14
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology. 2000;118(4):705-713. (Pubitemid 30171620)
-
(2000)
Gastroenterology
, vol.118
, Issue.4
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
Targan, S.R.4
Sinnett, D.5
Theoret, Y.6
Seidman, E.G.7
-
15
-
-
0035811191
-
Improved methods for determining the concentration of 6-thioguanine nucleotides and 6-methylmercaptopurine nucleotides in blood
-
DOI 10.1016/S0378-4347(00)00513-2, PII S0378434700005132
-
Pike MG, Franklin CL, Mays DC, Lipsky JJ, Lowry PW, Sandborn WJ. Improved methods for determining the concentration of 6-thioguanine nucleotides and 6-methylmercaptopurine nucleotides in blood. J Chromatogr B Biomed Sci Appl. 2001;757(1):1-9. (Pubitemid 32424452)
-
(2001)
Journal of Chromatography B: Biomedical Sciences and Applications
, vol.757
, Issue.1
, pp. 1-9
-
-
Pike, M.G.1
Franklin, C.L.2
Mays, D.C.3
Lipsky, J.J.4
Lowry, P.W.5
Sandborn, W.J.6
-
16
-
-
0032529469
-
Monitored high-dose azathioprine treatment reduces acute rejection episodes after renal transplantation
-
Bergan S, Rugstad HE, Bentdal O, et al. Monitored high-dose azathioprine treatment reduces acute rejection episodes after renal transplantation. Transplantation. 1998;66(3):334-339. (Pubitemid 28390215)
-
(1998)
Transplantation
, vol.66
, Issue.3
, pp. 334-339
-
-
Bergan, S.1
Rugstad, H.E.2
Bentdal, O.3
Sodal, G.4
Hartmann, A.5
Leivestad, T.6
Stokke, O.7
-
17
-
-
0030699368
-
Optimisation of azathioprine immunosuppression after organ transplantation by pharmacological measurements
-
Bergan S. Optimisation of azathioprine immunosuppression after organ transplantation by pharmacological measurements. BioDrugs. 1997;8(6):446-456. (Pubitemid 27517611)
-
(1997)
BioDrugs
, vol.8
, Issue.6
, pp. 446-456
-
-
Bergan, S.1
-
18
-
-
67449160247
-
Determination of thiopurine methyltransferase activity in red blood cells (RBC) by tandem mass spectrometry
-
abstract MP 222
-
Turgeon CT, Lacey JM, Magera MJ, et al. Determination of thiopurine methyltransferase activity in red blood cells (RBC) by tandem mass spectrometry [abstract MP 222]. J Am Soc Mass Spectrom. 2007;18(5):34S.
-
(2007)
J Am Soc Mass Spectrom
, vol.18
, Issue.5
-
-
Turgeon, C.T.1
Lacey, J.M.2
Magera, M.J.3
-
19
-
-
0031889642
-
Simultaneous determination of 6-thioguanine and methyl 6-mercaptopurine nucleotides of azathioprine in red blood cells by HPLC
-
Dervieux T, Boulieu R. Simultaneous determination of 6-thioguanine and methyl 6-mercaptopurine nucleotides of azathioprine in red blood cells by HPLC. Clin Chem. 1998;44(3):551-555. (Pubitemid 28141350)
-
(1998)
Clinical Chemistry
, vol.44
, Issue.3
, pp. 551-555
-
-
Dervieux, T.1
Boulieu, R.2
-
20
-
-
2542639314
-
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: Implications for therapy
-
DOI 10.1097/00007691-200406000-00016
-
Derijks LJ, Gilissen LP, Engels LG, et al. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Ther Drug Monit. 2004;26(3):311-318. (Pubitemid 38703020)
-
(2004)
Therapeutic Drug Monitoring
, vol.26
, Issue.3
, pp. 311-318
-
-
Derijks, L.J.J.1
Gilissen, L.P.L.2
Engels, L.G.J.B.3
Bos, L.P.4
Bus, P.J.5
Lohman, J.J.H.M.6
Curvers, W.L.7
Van Deventer, S.J.H.8
Hommes, D.W.9
Hooymans, P.M.10
-
21
-
-
0037237923
-
Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD
-
Seidman EG. Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD. Rev Gastroenterol Disord. 2003; 3(suppl 1):S30-S38. (Pubitemid 36395165)
-
(2003)
Reviews in Gastroenterological Disorders
, vol.3
, Issue.SUPPL. 1
-
-
Seidman, E.G.1
-
22
-
-
0022643339
-
Azathioprine and severe bone marrow depression
-
Maddocks JL, Lennard L, Amess J, Amos R, Thomas RM. Azathioprine and severe bone marrow depression. Lancet. 1986;1(8473):156.
-
(1986)
Lancet
, vol.1
, Issue.8473
, pp. 156
-
-
Maddocks, J.L.1
Lennard, L.2
Amess, J.3
Amos, R.4
Thomas, R.M.5
-
23
-
-
4544294487
-
The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease
-
DOI 10.1111/j.1572-0241.2004.30415.x
-
Goldenberg BA, Rawsthorne P, Bernstein CN. The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease. Am J Gastroenterol. 2004;99(9):1744-1748. (Pubitemid 39237503)
-
(2004)
American Journal of Gastroenterology
, vol.99
, Issue.9
, pp. 1744-1748
-
-
Goldenberg, B.A.1
Rawsthorne, P.2
Bernstein, C.N.3
-
24
-
-
33646011261
-
Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: A meta-analysis
-
Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology. 2006;130(4):1047-1053.
-
(2006)
Gastroenterology
, vol.130
, Issue.4
, pp. 1047-1053
-
-
Osterman, M.T.1
Kundu, R.2
Lichtenstein, G.R.3
Lewis, J.D.4
-
25
-
-
33745608050
-
Impact of thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations in patients with chronic inflammatory diseases
-
DOI 10.1196/annals.1351.048
-
Schedel J, Godde A, Schutz E, et al. Impact of thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations in patients with chronic inflammatory diseases. Ann N Y Acad Sci. 2006;1069:477-491. (Pubitemid 43989892)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1069
, pp. 477-491
-
-
Schedel, J.1
Godde, A.2
Schutz, E.3
Bongartz, T.A.4
Lang, B.5
Scholmerich, J.6
Muller-Ladner, U.7
-
26
-
-
10744223009
-
Pharmacological monitoring of azathioprine therapy
-
DOI 10.1080/00365520310005082
-
Reuther LO, Sonne J, Larsen NE, et al. Pharmacological monitoring of azathioprine therapy. Scand J Gastroenterol. 2003;38(9):972-977. (Pubitemid 37153627)
-
(2003)
Scandinavian Journal of Gastroenterology
, vol.38
, Issue.9
, pp. 972-977
-
-
Reuther, L.O.1
Sonne, J.2
Larsen, N.E.3
Larsen, B.4
Christensen, S.5
Rasmussen, S.N.6
Tofteng, F.7
Haaber, A.8
Johansen, N.9
Kjeldsen, J.10
Schmiegelow, K.11
-
27
-
-
0032801395
-
Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine
-
Dervieux T, Medard Y, Baudouin V, et al. Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine. Br J Clin Pharmacol. 1999;48(6):793-800.
-
(1999)
Br J Clin Pharmacol
, vol.48
, Issue.6
, pp. 793-800
-
-
Dervieux, T.1
Medard, Y.2
Baudouin, V.3
-
28
-
-
0035344456
-
High 6-thioguanine nucleotide levels and low thiopurine methyltransferase activity in patients with lupus erythematosus treated with azathioprine
-
Decaux G, Horsmans Y, Houssiau F, Desager JP. High 6-thioguanine nucleotide levels and low thiopurine methyltransferase activity in patients with lupus erythematosus treated with azathioprine. Am J Ther. 2001;8(3):147-150. (Pubitemid 33753110)
-
(2001)
American Journal of Therapeutics
, vol.8
, Issue.3
, pp. 147-150
-
-
Decaux, G.1
-
29
-
-
0034771188
-
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
-
DOI 10.1136/gut.49.5.665
-
Lowry PW, Franklin CL, Weaver AL, et al. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut. 2001;49(5):665-670. (Pubitemid 32989203)
-
(2001)
Gut
, vol.49
, Issue.5
, pp. 665-670
-
-
Lowry, P.W.1
Franklin, C.L.2
Weaver, A.L.3
Gennett Pike, M.4
Mays, D.C.5
Tremaine, W.J.6
Lipsky, J.J.7
Sandborn, W.J.8
-
30
-
-
0035134907
-
Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease
-
Belaiche J, Desager JP, Horsmans Y, Louis E. Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease. Scand J Gastroenterol. 2001;36(1):71-76. (Pubitemid 32147184)
-
(2001)
Scandinavian Journal of Gastroenterology
, vol.36
, Issue.1
, pp. 71-76
-
-
Belaiche, J.1
Desager, J.P.2
Horsmans, Y.3
Louis, E.4
-
31
-
-
27644565720
-
Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: Early experience of use in clinical practice
-
DOI 10.1111/j.1445-5994.2005.00904.x
-
Gearry RB, Barclay ML, Roberts RL, et al. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice. Intern Med J. 2005;35(10):580-585. (Pubitemid 41564403)
-
(2005)
Internal Medicine Journal
, vol.35
, Issue.10
, pp. 580-585
-
-
Gearry, R.B.1
Barclay, M.L.2
Roberts, R.L.3
Harraway, J.4
Zhang, M.5
Pike, L.S.6
George, P.M.7
Florkowski, C.M.8
-
32
-
-
0034510578
-
Genetic polymorphism and outcomes with azathioprine and 6-mercaptopurine
-
Gardiner SJ, Begg EJ, Barclay ML, Kirkpatrick CM. Genetic polymorphism and outcomes with azathioprine and 6-mercaptopurine. Adverse Drug React Toxicol Rev. 2000;19(4):293-312. (Pubitemid 32117719)
-
(2000)
Adverse Drug Reactions and Toxicological Reviews
, vol.19
, Issue.4
, pp. 293-312
-
-
Gardiner, S.J.1
Begg, E.J.2
Barclay, M.L.3
Kirkpatrick, C.M.J.4
-
33
-
-
33748542279
-
Next steps on the thiopurine methyltransferase 6-thioguanine nucleotide pathway
-
DOI 10.1097/01.mpg.0000237940.50791.70, PII 0000517620060900000003
-
Colletti RB. Next steps on the thiopurine methyltransferase 6-thioguanine nucleotide pathway. J Pediatr Gastroenterol Nutr. 2006;43(3):282-283. (Pubitemid 44368180)
-
(2006)
Journal of Pediatric Gastroenterology and Nutrition
, vol.43
, Issue.3
, pp. 282-283
-
-
Colletti, R.B.1
-
34
-
-
0035037706
-
Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
-
DOI 10.1136/gut.48.5.642
-
Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimize azathioprine therapy in patients with inflammatory bowel disease. Gut. 2001;48(5):642-646. (Pubitemid 32378583)
-
(2001)
Gut
, vol.48
, Issue.5
, pp. 642-646
-
-
Cuffari, C.1
Hunt, S.2
Bayless, T.3
-
35
-
-
33748555869
-
Evolution of thiopurine use in pediatric inflammatory bowel disease in an academic center
-
DOI 10.1097/01.mpg.0000228135.31793.9f, PII 0000517620060900000010
-
Banerjee S, Bishop WP. Evolution of thiopurine use in pediatric inflammatory bowel disease in an academic center. J Pediatr Gastroenterol Nutr. 2006;43(3):324-330. (Pubitemid 44368187)
-
(2006)
Journal of Pediatric Gastroenterology and Nutrition
, vol.43
, Issue.3
, pp. 324-330
-
-
Banerjee, S.1
Bishop, W.P.2
|