-
1
-
-
36749086523
-
Review article: the evidence base for interventions used to maintain remission in Crohn's disease
-
Akobeng A.K. Review article: the evidence base for interventions used to maintain remission in Crohn's disease. Aliment Pharmacol Ther 27 (2008) 11-18
-
(2008)
Aliment Pharmacol Ther
, vol.27
, pp. 11-18
-
-
Akobeng, A.K.1
-
2
-
-
0028790186
-
A controlled double blind study of azathioprine in the management of Crohn's disease
-
Candy S., Wright J., Gerber M., Adams G., Gerig M., and Goodman R. A controlled double blind study of azathioprine in the management of Crohn's disease. Gut 37 (1995) 674-678
-
(1995)
Gut
, vol.37
, pp. 674-678
-
-
Candy, S.1
Wright, J.2
Gerber, M.3
Adams, G.4
Gerig, M.5
Goodman, R.6
-
3
-
-
0033770169
-
A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease
-
Markowitz J., Grancher K., Kohn N., Lesser M., and Daum F. A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease. Gastroenterology 119 (2000) 895-902
-
(2000)
Gastroenterology
, vol.119
, pp. 895-902
-
-
Markowitz, J.1
Grancher, K.2
Kohn, N.3
Lesser, M.4
Daum, F.5
-
5
-
-
39449085441
-
Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial
-
D'Haens G., Baert F., van Assche G., et al. Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 371 (2008) 660-667
-
(2008)
Lancet
, vol.371
, pp. 660-667
-
-
D'Haens, G.1
Baert, F.2
van Assche, G.3
-
6
-
-
33645958908
-
Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial
-
Lemann M., Mary J.Y., Duclos B., et al. Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial. Gastroenterology 130 (2006) 1054-1061
-
(2006)
Gastroenterology
, vol.130
, pp. 1054-1061
-
-
Lemann, M.1
Mary, J.Y.2
Duclos, B.3
-
7
-
-
29244457275
-
Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
-
Ardizzone S., Maconi G., Russo A., Imbesi V., Colombo E., and Bianchi Porro G. Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 55 (2006) 47-53
-
(2006)
Gut
, vol.55
, pp. 47-53
-
-
Ardizzone, S.1
Maconi, G.2
Russo, A.3
Imbesi, V.4
Colombo, E.5
Bianchi Porro, G.6
-
8
-
-
84968747329
-
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
-
Review
-
Timmer A., McDonald J.W., and Macdonald J.K. Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev 1 (2007 Jan 24) CD000478 Review
-
(2007)
Cochrane Database Syst Rev
, Issue.1
-
-
Timmer, A.1
McDonald, J.W.2
Macdonald, J.K.3
-
9
-
-
37549024231
-
Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer
-
Karran P., and Attard N. Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer. Nat Rev Cancer 8 (2008) 24-36
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 24-36
-
-
Karran, P.1
Attard, N.2
-
10
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 43 (1992) 329-339
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
11
-
-
0242464926
-
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
-
Tiede I., Fritz G., Strand S., et al. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest 111 (2003) 1133-1145
-
(2003)
J Clin Invest
, vol.111
, pp. 1133-1145
-
-
Tiede, I.1
Fritz, G.2
Strand, S.3
-
12
-
-
13244277605
-
Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines
-
Thomas C.W., Myhre G.M., Tschumper R., et al. Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines. J Pharmacol Exp Ther 312 (2005) 537-545
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 537-545
-
-
Thomas, C.W.1
Myhre, G.M.2
Tschumper, R.3
-
13
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky M.C., Yang H., Hassard P.V., et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 122 (2002) 904-915
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.2
Hassard, P.V.3
-
14
-
-
52149099443
-
Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease
-
Ansari A., Arenas M., Greenfield S.M., et al. Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease. Aliment Pharmacol Ther 28 (2008) 973-983
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 973-983
-
-
Ansari, A.1
Arenas, M.2
Greenfield, S.M.3
-
15
-
-
24344480999
-
Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine
-
Sparrow M.P., Hande S.A., Friedman S., et al. Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. Aliment Pharmacol Ther 22 (2005) 441-446
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 441-446
-
-
Sparrow, M.P.1
Hande, S.A.2
Friedman, S.3
-
16
-
-
33846820178
-
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine
-
Sparrow M.P., Hande S.A., Friedman S., Cao D., and Hanauer S.B. Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine. Clin Gastroenterol Hepatol 5 (2007) 209-214
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 209-214
-
-
Sparrow, M.P.1
Hande, S.A.2
Friedman, S.3
Cao, D.4
Hanauer, S.B.5
-
17
-
-
42449087386
-
Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature
-
Witte T.N., and Ginsberg A.L. Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature. Can J Gastroenterol 22 (2008) 181-185
-
(2008)
Can J Gastroenterol
, vol.22
, pp. 181-185
-
-
Witte, T.N.1
Ginsberg, A.L.2
-
18
-
-
49849088177
-
Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease
-
Ansari A., Elliott T., Baburajan B., et al. Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease. Aliment Pharmacol Ther 28 (2008) 734-741
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 734-741
-
-
Ansari, A.1
Elliott, T.2
Baburajan, B.3
-
19
-
-
52149089035
-
Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease
-
Rahhal R.M., and Bishop W.P. Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease. Inflamm Bowel Dis 12 (2008) 1678-1682
-
(2008)
Inflamm Bowel Dis
, Issue.12
, pp. 1678-1682
-
-
Rahhal, R.M.1
Bishop, W.P.2
-
20
-
-
0041699969
-
Veno-occlusive disease (VOD) in Crohn's disease (CD) treated with azathioprine
-
Holtmann M., Schreiner O., Kohler H., et al. Veno-occlusive disease (VOD) in Crohn's disease (CD) treated with azathioprine. Dig Dis Sci 48 (2003) 1503-1505
-
(2003)
Dig Dis Sci
, vol.48
, pp. 1503-1505
-
-
Holtmann, M.1
Schreiner, O.2
Kohler, H.3
-
21
-
-
34948824782
-
Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine
-
Vernier-Massouille G., Cosnes J., Lemann M., et al. Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine. Gut 56 (2007) 1404-1409
-
(2007)
Gut
, vol.56
, pp. 1404-1409
-
-
Vernier-Massouille, G.1
Cosnes, J.2
Lemann, M.3
-
22
-
-
0026465403
-
High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample
-
Lennard L., and Singleton H.J. High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample. J Chromatogr 583 (1992) 83-90
-
(1992)
J Chromatogr
, vol.583
, pp. 83-90
-
-
Lennard, L.1
Singleton, H.J.2
-
23
-
-
0028073102
-
High-performance liquid chromatographic assay of human red blood cell thiopurine methyltransferase activity
-
Lennard L., and Singleton H.J. High-performance liquid chromatographic assay of human red blood cell thiopurine methyltransferase activity. J Chromatogr B Biomed Appl 661 (1994) 25-33
-
(1994)
J Chromatogr B Biomed Appl
, vol.661
, pp. 25-33
-
-
Lennard, L.1
Singleton, H.J.2
-
24
-
-
0019319257
-
A simple index of Crohn's-disease activity
-
Harvey R.F., and Bradshaw J.M. A simple index of Crohn's-disease activity. Lancet 1 (1980) 514
-
(1980)
Lancet
, vol.1
, pp. 514
-
-
Harvey, R.F.1
Bradshaw, J.M.2
-
25
-
-
0023521441
-
Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study
-
Schroeder K.W., Tremaine W.J., and Ilstrup D.M. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 317 (1987) 1625-1629
-
(1987)
N Engl J Med
, vol.317
, pp. 1625-1629
-
-
Schroeder, K.W.1
Tremaine, W.J.2
Ilstrup, D.M.3
-
26
-
-
0029794073
-
6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity
-
Cuffari C., Theoret Y., Latour S., and Seidman G. 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity. Gut 39 (1996) 401-406
-
(1996)
Gut
, vol.39
, pp. 401-406
-
-
Cuffari, C.1
Theoret, Y.2
Latour, S.3
Seidman, G.4
-
27
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky M.C., Lamothe S., Yang H.Y., et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 118 (2000) 705-713
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
-
28
-
-
16444367834
-
6-tioguanine monitoring in steroid-dependent patients with inflammatory bowel diseases receiving azathioprine
-
Roblin X., Serre-Debeauvais F., Phelip J.M., et al. 6-tioguanine monitoring in steroid-dependent patients with inflammatory bowel diseases receiving azathioprine. Aliment Pharmacol Ther 21 (2005) 829-839
-
(2005)
Aliment Pharmacol Ther
, vol.21
, pp. 829-839
-
-
Roblin, X.1
Serre-Debeauvais, F.2
Phelip, J.M.3
-
29
-
-
33646011261
-
Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis
-
Osterman M.T., Kundu R., Lichtenstein G.R., and Lewis J.D. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 130 (2006) 1047-1053
-
(2006)
Gastroenterology
, vol.130
, pp. 1047-1053
-
-
Osterman, M.T.1
Kundu, R.2
Lichtenstein, G.R.3
Lewis, J.D.4
-
30
-
-
0021028642
-
Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol
-
Zimm S., Collins J.M., O'Neill D., Chabner B.A., and Poplack D.G. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol. Clin Pharmacol Ther 34 (1983) 810-817
-
(1983)
Clin Pharmacol Ther
, vol.34
, pp. 810-817
-
-
Zimm, S.1
Collins, J.M.2
O'Neill, D.3
Chabner, B.A.4
Poplack, D.G.5
-
31
-
-
0027161587
-
Low-dose allopurinol plus azathioprine/cyclosporin/prednisolone, a novel immunosuppressive regimen
-
Chocair P., Duley J., Simmonds H.A., et al. Low-dose allopurinol plus azathioprine/cyclosporin/prednisolone, a novel immunosuppressive regimen. Lancet 342 (1993) 83-84
-
(1993)
Lancet
, vol.342
, pp. 83-84
-
-
Chocair, P.1
Duley, J.2
Simmonds, H.A.3
-
32
-
-
36549053255
-
The role of xanthine oxidase in thiopurine metabolism: a case report
-
Wong D.R., Derijks L.J., den Dulk M.O., Gemmeke E.H., and Hooymans P.M. The role of xanthine oxidase in thiopurine metabolism: a case report. Ther Drug Monit 29 (2007) 845-848
-
(2007)
Ther Drug Monit
, vol.29
, pp. 845-848
-
-
Wong, D.R.1
Derijks, L.J.2
den Dulk, M.O.3
Gemmeke, E.H.4
Hooymans, P.M.5
-
33
-
-
49849105122
-
The influence of xanthine oxidase on thiopurine metabolism in Crohn's disease
-
Ansari A., Aslam Z., De Sica A., et al. The influence of xanthine oxidase on thiopurine metabolism in Crohn's disease. Aliment Pharmacol Ther 28 6 (2008) 749-757
-
(2008)
Aliment Pharmacol Ther
, vol.28
, Issue.6
, pp. 749-757
-
-
Ansari, A.1
Aslam, Z.2
De Sica, A.3
-
34
-
-
28844490574
-
Observations on the use of allopurinol in combination with azathioprine or mercaptopurine
-
Duley J.A., Chocair P.R., and Florin T.H. Observations on the use of allopurinol in combination with azathioprine or mercaptopurine. Aliment Pharmacol Ther 22 (2005) 1161-1162
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 1161-1162
-
-
Duley, J.A.1
Chocair, P.R.2
Florin, T.H.3
-
35
-
-
0026637822
-
Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: a new approach
-
Salim A.S. Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: a new approach. J Lab Clin Med 119 (1992) 710-717
-
(1992)
J Lab Clin Med
, vol.119
, pp. 710-717
-
-
Salim, A.S.1
-
36
-
-
0033806902
-
Allopurinol in addition to 5-aminosalicylic acid based drugs for the maintenance treatment of ulcerative colitis
-
Jarnerot G., Strom M., Danielsson A., et al. Allopurinol in addition to 5-aminosalicylic acid based drugs for the maintenance treatment of ulcerative colitis. Aliment Pharmacol Ther 14 (2000) 1159-1162
-
(2000)
Aliment Pharmacol Ther
, vol.14
, pp. 1159-1162
-
-
Jarnerot, G.1
Strom, M.2
Danielsson, A.3
-
37
-
-
17944361923
-
Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study
-
Joelsson M., Andersson M., Bark T., et al. Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study. Scand J Gastroenterol 36 (2001) 1179-1184
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 1179-1184
-
-
Joelsson, M.1
Andersson, M.2
Bark, T.3
|