Matrix metalloproteinase-28 deletion exacerbates cardiac dysfunction and rupture after myocardial infarction in mice by inhibiting M2 macrophage activation

Circulation Research

Volumn 112, Issue 4, 2013, Pages 675-688

  Ma, Yonggang ^a,b   Halade, Ganesh V ^a,b   Zhang, Jianhua ^a,b   Ramirez, Trevi A ^a,b   Levin, Daniel ^a,b   Voorhees, Andrew ^a,c   Jin, Yu Fang ^a,c   Han, Hai Chao ^a,c   Manicone, Anne M ^d   Lindsey, Merry L ^a,b  

^a San Antonio Cardiovascular Proteomics Center   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c The University of Texas at San Antonio   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

fibroblast; inflammation; macrophage phenotype; MMP 28; myocardial infarction

Indexed keywords

COLLAGEN; GELATINASE B; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 28; MESSENGER RNA; PROTEIN LYSINE 6 OXIDASE; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CROSS LINKING; ENZYME ACTIVATION; FEMALE; GENOTYPE; HEART DISEASE; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE CELL; HEART RUPTURE; LUNG EDEMA; MACROPHAGE; MALE; MORTALITY; MOUSE; MYOFIBROBLAST; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TENSILE STRENGTH;

ANIMALS; CELL ADHESION MOLECULES; CICATRIX; COLLAGEN; CYTOKINES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HEART RUPTURE; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES, SECRETED; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; MYOFIBROBLASTS; PROTEIN-LYSINE 6-OXIDASE; PULMONARY EDEMA; RECEPTORS, CYTOKINE; TRANSCRIPTION, GENETIC; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84874285627     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.300502     Document Type: Article

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