A collagen α2(I) mutation impairs healing after experimental myocardial infarction

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 113-122

  Hofmann, Ulrich ^a   Bonz, Andreas ^a,b   Frantz, Stefan ^a   Hu, Kai ^a   Waller, Christiane ^c   Roemer, Katrin ^a   Wolf, Jrgen ^a   Gattenlöhner, Stefan ^d   Bauersachs, Johann ^e   Ertl, Georg ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b Center for Cardiology   (Germany)

^c UNIVERSITY HOSPITAL ULM   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN ALPHA2 CHAIN; COLLAGEN DERIVATIVE; COLLAGEN TYPE 1; GELATINASE B; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME INHIBITION; EXPERIMENTAL STUDY; GENOTYPE; HEART INFARCTION; HETEROZYGOSITY; HOMOZYGOSITY; LEUKOPENIA; MALE; MOUSE; NONHUMAN; OSTEOGENESIS IMPERFECTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; WOUND HEALING IMPAIRMENT;

ANIMALS; CICATRIX; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; GRANULOCYTES; MALE; MATRIX METALLOPROTEINASE 9; MICE; MUTATION; MYOCARDIAL INFARCTION; OSTEOGENESIS IMPERFECTA; RNA, MESSENGER; SURVIVAL RATE; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR SEPTAL RUPTURE; WOUND HEALING;

EID: 83455179716     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.09.033     Document Type: Article

References (45)

1. I.M. Orioloi, E.E. Castilla, J.G. Barbosa-Neto The birth prevalance rates for the skeletal dysplasias J Med Genet 23 1986 328 332 (Pubitemid 16070733)
2. E. Martin, J.R. Shapiro Osteogenesis imperfecta: epidemiology and pathophysiology Curr Osteoporos Rep 5 2007 91 97 (Pubitemid 47571959)
3. S.J. McAllion, C.R. Paterson Causes of death in osteogenesis imperfecta J Clin Pathol 49 1996 627 630 (Pubitemid 26264386)
4. T.F. Robinson, L. Cohen-Gould, S.M. Factor Skeletal framework of mammalian heart muscle Arrangement of inter- and pericellular connective tissue structures Lab Invest 49 1983 482 498 (Pubitemid 13021742)
5. A. Lijoi, S. Cisico, E. Caputo, F. Scarano, E. Parodi, G.C. Passerone Left ventricular rupture after mitral valve replacement in a patient with osteogenesis imperfecta tarda Tex Heart Inst J 26 1999 295 297 (Pubitemid 30067019)
6. R.S. Wong, F.M. Follis, B.K. Shively, J.A. Wernly Osteogenesis imperfecta and cardiovascular diseases Ann Thorac Surg 60 1995 1439 1443
7. S.G. Reddy, W.C. Roberts Frequency of rupture of the left ventricular free wall or ventricular septum among necropsy cases of fatal acute myocardial infarction since introduction of coronary care units Am J Cardiol 63 1989 906 911 (Pubitemid 19105123)
8. M.H. McMullan, M.D. Maples, T.L. Kilgore Jr, S.H. Hindman Surgical experience with left ventricular free wall rupture Ann Thorac Surg 71 2001 1894 1898
9. A.C. Pouleur, E. Barkoudah, H. Uno, H. Skali, P.V. Finn, S.L. Zelenkofske, Y.N. Belenkov, V. Mareev, E.J. Velazquez, J.L. Rouleau, A.P. Maggioni, L. Køber, R.M. Califf, J.J. McMurray, M.A. Pfeffer, S.D. Solomon VALIANT Investigators Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both Circulation 122 2010 597 602
10. S. Frantz, J. Bauersachs, G. Ertl Post-infarct remodelling: contribution of wound healing and inflammation Cardiovasc Res 81 2009 474 481
11. W.M. Blankesteijn, E. Creemers, E. Lutgens, J.P. Cleutjens, M.J. Daemen, J.F. Smits Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice Acta Physiol Scand 173 2001 75 82 (Pubitemid 32948336)
12. S.C. Tyagi, S.E. Campbell, H.K. Reddy, E. Tjahja, D.J. Voelker Matrix metalloproteinase activity expression in infarcted, noninfarcted and dilated cardiomyopathic human hearts Mol Cell Biochem 155 1996 13 21 (Pubitemid 26038062)
13. D. Vanhoutte, M. Schellings, Y. Pinto, S. Heymans Relevance of matrix metalloproteinases and their inhibitors after myocardial infarction: a temporal and spatial window Cardiovasc Res 69 2006 604 613 (Pubitemid 43139724)
14. S. Heymans, A. Luttun, D. Nuyens, G. Theilmeier, E. Creemers, L. Moons, G.D. Dyspersin, J.P. Cleutjens, M. Shipley, A. Angellilo, M. Levi, O. Nbe, A. Baker, E. Keshet, F. Lupu, J.M. Herbert, J.F. Smits, S.D. Shapiro, M. Baes, M. Borgers, D. Collen, M.J. Daemen, P. Carmeliet Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Nat Med 5 1999 1135 1142 (Pubitemid 29474417)
15. A. Ducharme, S. Frantz, M. Aikawa, E. Rabkin, M. Lindsey, L.E. Rohde, F.J. Schoen, R.A. Kelly, Z. Werb, P. Libby, R.T. Lee Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction J Clin Invest 106 2000 55 62 (Pubitemid 30437240)
16. S. Hayashidani, H. Tsutsui, M. Ikeuchi, T. Shiomi, H. Matsusaka, T. Kubota, K. Imanaka-Yoshida, T. Itoh, A. Takeshita Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction Am J Physiol Heart Circ Physiol 285 2003 H1229 H1235
17. J.P. Cleutjens, J.C. Kandala, E. Guarda, R.V. Guntaka, K.T. Weber Regulation of collagen degradation in the rat myocardium after infarction J Mol Cell Cardiol 27 1995 1281 1292
18. S.D. Chipman, H.O. Sweet, J.R. McBride DJ, M.T. Davisson, J.R. Marks SC, A.R. Shuldiner, R.J. Wenstrup, D.W. Rowe, J.R. Shapiro Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta Proc Natl Acad Sci USA 90 1993 1701 1705 (Pubitemid 23069924)
19. G. Ertl, S. Frantz Wound model of myocardial infarction J Am Physiol Heart Circ Physiol 288 2005 H981 H983
20. G. Ertl, S. Frantz Healing after myocardial infarction Cardiovasc Res 66 2005 22 32 (Pubitemid 40360705)
21. J.R. McBride DJ, V. Choe, J.R. Shapiro, B. Brodsky Altered collagen structure in mouse tail tendon lacking the alpha 2(I) chain J Mol Biol 270 1997 275 284 (Pubitemid 27296687)
22. S.M. Weis, J.L. Emery, K.D. Becker, D.J. McBride Jr, J.H. Omens, A.D. McCulloch Myocardial mechanics and collagen structure in the osteogenesis imperfecta murine (oim) Circ Res 87 2000 663 669
23. J. Saban, D. King PCR genotyping of oim mutant mice Biotechniques 21 1996 190 192 (Pubitemid 26271668)
24. S. Frantz, K. Hu, J. Widder, B. Bayer, C.C. Witzel, I. Schmidt, P. Galuppo, J. Strotmann, G. Ertl, J. Bauersachs Peroxisome proliferator activated-receptor agonism and left ventricular remodeling in mice with chronic myocardial infarction Br J Pharmacol 141 2004 9 14 (Pubitemid 38241158)
25. S. Frantz, K. Hu, B. Bayer, S. Gerondakis, J. Strotmann, A. Adamek, G. Ertl, J. Bauersachs Absence of NF-kappaB subunit p50 improves heart failure after myocardial infarction FASEB J 20 2006 1918 1920
26. D. Fraccarollo, P. Galuppo, J. Bauersachs, G. Ertl Collagen accumulation after myocardial infarction: effects of ETA receptor blockade and implications for early remodeling Cardiovasc Res 2002 559 567 (Pubitemid 34595414)
27. J.M. Daley, A.A. Thomas, M.D. Connolly, J.S. Reichner, J.E. Albina Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice J Leukoc Biol 83 2008 64 70
28. A.K. Prall, G.M. Longo, W.G. Mayhan, E.A. Waltke, B. Fleckten, R.W. Thompson, B.T. Baxter Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice J Vasc Surg 35 2002 923 929
29. J. Cleutjens, E. Creemers Integration of concepts: cardiac extracellular matrix remodeling after myocardial infarction J Card Fail 8 6 Suppl 2002 S344 S348
30. X.M. Gao, R.J. Dilley, C.S. Samuel, E. Percy, M.J. Fullerton, A.M. Dart, X.J. Du Lower risk of postinfarct rupture in mouse heart overexpressing beta 2-adrenergic receptors: importance of collagen content J Cardiovasc Pharmacol 40 2002 632 640
31. X.M. Gao, Q. Xu, H. Kiriazis, A.M. Dart, X.J. Du Mouse model of post-infarct ventricular rupture: time course, strain- and gender-dependency, tensile strength, and histopathology Cardiovasc Res 65 2005 469 477 (Pubitemid 40082489)
32. P.B. Oliva, S.C. Hammill, W.D. Edwards Cardiac rupture, a clinically predictable complication of acute myocardial infarction: report of 70 cases with clinicopathologic correlations J Am Coll Cardiol 22 1993 720 726 (Pubitemid 23256931)
33. E.V. Lautsch, K.W. Lanks Pathogenesis of cardiac rupture Arch Pathol 84 1967 264 271
34. P. Krishnamurthy, J.T. Peterson, V. Subramanian, M. Singh, K. Singh Inhibition of matrix metalloproteinases improves left ventricular function in mice lacking osteopontin after myocardial infarction Mol Cell Biochem 322 2009 53 62
35. S. Matsumura, S. Iwanaga, S. Mochizuki, H. Okamoto, S. Ogawa, Y. Okada Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice J Clin Invest 115 2005 599 609 (Pubitemid 40322234)
36. M. Sun, F. Dawood, W.H. Wen, M. Chen, I. Dixon, L.A. Kirshenbaum, P.P. Liu Excessive tumor necrosis factor activation after infarction contributes to susceptibility of myocardial rupture and left ventricular dysfunction Circulation 110 2004 3221 3228 (Pubitemid 39525069)
37. K. Tsujita, K. Kaikita, T. Hayasaki, T. Honda, H. Kobayashi, N. Sakashita, H. Suzuki, T. Kodama, H. Ogawa, M. Takeya Targeted deletion of class A macrophage scavenger receptor increases the risk of cardiac rupture after experimental myocardial infarction Circulation 115 2007 1904 1911 (Pubitemid 46598904)
38. N.A. Trueblood, Z. Xie, C. Communal, F. Sam, S. Ngoy, L. Liaw, A.W. Jenkins, J. Wang, D.B. Sawyer, O.H. Bing, C.S. Apstein, W.S. Colucci, K. Singh Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin Circ Res 88 2001 1080 1087 (Pubitemid 34137122)
39. H. Matsusaka, T. Ide, S. Matsushima, M. Ikeuchi, T. Kubota, K. Sunagawa, S. Kinugawa, H. Tsutsui Targeted deletion of p53 prevents cardiac rupture after myocardial infarction in mice Cardiovasc Res 70 2006 457 465
40. F.W. Sutherland, F.J. Guell, V.L. Pathi, S.K. Naik Postinfarction ventricular free wall rupture: strategies for diagnosis and treatment Ann Thorac Surg 61 1996 1281 1285 (Pubitemid 126336094)
41. J.B. Atkinson, M. Robinowitz, H.A. McAllister, R. Virmani Association of eosinophils with cardiac rupture Hum Pathol 16 1985 562 568 (Pubitemid 15049630)
42. F.J. Villarreal, M. Griffin, J. Omens, W. Dillmann, J. Nguyen, J. Covell Early Short-Term Treatment With Doxycylin Modulates Postinfarction Left Ventricular Remodeling Circulation 108 2003 1487 1492 (Pubitemid 37176456)
43. M.L. Lindsey, J. Yoshioka, C. MacGillivray, S. Muangman, J. Gannon, A. Verghese, M. Aikawa, P. Libby, S.M. Krane, R.T. Lee Effect of a cleavage-resistant collagen mutation on left ventricular remodeling [Erratum appeared in Circ Res 2004, 95: e34] Circ Res 93 2003 238 245 (Pubitemid 36993235)
44. J.P. Cleutjens, M.J. Verluyten, J.F. Smiths, M.J. Daemen Collagen remodeling after myocardial infarction in the rat heart Am J Pathol 147 1995 325 338
45. S. Migliaccio, G. Barbaro, R. Fornari, G. Di Lorenzo, M. Celli, C. Lubrano, S. Falcone, E. Fabbrini, E. Greco, A. Zambrano, M. Brama, G. Prossomariti, S. Marzano, M. Marini, F. Conti, P. D'Eufemia, G. Spera Impairment of diastolic function in adult patients affected by osteogenesis imperfecta clinically asymptomatic for cardiac disease: casuality or causality? Int J Cardiol 131 2009 200 203