Polypeptide cationic micelles mediated co-delivery of docetaxel and siRNA for synergistic tumor therapy

Biomaterials

Volumn 34, Issue 13, 2013, Pages 3431-3438

  Zheng, Cuifang ^a   Zheng, Mingbin ^a   Gong, Ping ^a   Deng, Jizhe ^a   Yi, Huqiang ^a   Zhang, Pengfei ^a   Zhang, Yijuan ^a   Liu, Peng ^a   Ma, Yifan ^a   Cai, Lintao ^a  

^a SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

Author keywords

Co delivery; DTX; Polypeptide micelle; SiRNA; Synergistic tumor therapy

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTICANCER DRUG; BCL-2 GENE; BCL-2MRNA; CANCER THERAPY; CATIONIC MICELLES; CHEMOTHERAPEUTIC DRUGS; CO DELIVERIES; DIFFERENT MECHANISMS; DOCETAXEL; DOWN-REGULATION; DTX; L-LEUCINE; L-LYSINE; MURINE MODEL; NANOPARTICLE (NPS); NEGATIVELY CHARGED; SINGLE NANOPARTICLE; SIRNA; SMALL INTERFERING RNA (SIRNA); SYNERGISTIC EFFECT; THERAPEUTIC STRATEGY; TUMOR GROWTH; TUMOR THERAPY;

AMINO ACIDS; BLOCK COPOLYMERS; DRUG PRODUCTS; MICELLES; ONCOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RNA; TUMORS;

GENE THERAPY;

BIOMATERIAL; DOCETAXEL; LEUCINE; MACROGOL; NANOPARTICLE; POLYLYSINE; PROTEIN BCL 2; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENTIATION; FEMALE; GENE SILENCING; GENE VECTOR; HUMAN; HUMAN CELL; HYDROPHOBICITY; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; STATIC ELECTRICITY; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CATIONS; CELL PROLIFERATION; COLLOIDS; DRUG DELIVERY SYSTEMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICELLES; NANOPARTICLES; NEOPLASMS; PEPTIDES; POLYMERS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; RNA, SMALL INTERFERING; TAXOIDS; TISSUE DISTRIBUTION; TRANSFECTION;

MURINAE;

EID: 84874243933     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.053     Document Type: Article

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