In silico multi-scale model of transport and dynamic seeding in a bone tissue engineering perfusion bioreactor

Biotechnology and Bioengineering

Volumn 110, Issue 4, 2013, Pages 1221-1230

  Spencer, T J ^a   Hidalgo Bastida, L A ^b   Cartmell, S H ^b   Halliday, I ^a   Care, C M ^a  

^a SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Bone tissue engineering; Lattice Boltzmann; Mathematical model; Perfusion bioreactor; Wall shear stress

Indexed keywords

BIOREACTOR DESIGN; BONE TISSUE; BONE TISSUE ENGINEERING; CELLULAR DISTRIBUTIONS; COMPLEX SCAFFOLDS; COUPLED MODELS; DYNAMIC SEEDING; FLOW PROPERTIES; FUTURE DESIGNS; IN-SILICO; LATTICE BOLTZMANN; MICROCOMPUTED TOMOGRAPHY; MODERN HIGH PERFORMANCE; MULTISCALE MODELS; PERFUSION BIOREACTOR; POLY-L-LACTIDE; PORE SCALE; POROUS FLOW; POROUS SCAFFOLD; SEEDING METHOD; TIME-SCALES; VESSEL DESIGN; WALL SHEAR STRESS;

BIOCONVERSION; BIOREACTORS; BONE; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; DESIGN; MATHEMATICAL MODELS; TISSUE;

SCAFFOLDS (BIOLOGY);

ADHESION; ARTICLE; BIOREACTOR; BIOREACTOR DESIGN; BONE TISSUE; CELL ADHESION; CELL SEPARATION; CELLULAR DISTRIBUTION; COMPUTER MODEL; COMPUTER SIMULATION; DIFFUSION COEFFICIENT; FLOW RATE; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; OXYGEN DIFFUSION; SHEAR STRESS; THERMODYNAMICS; TISSUE ENGINEERING;

BIOREACTORS; BONE AND BONES; COMPUTER SIMULATION; TISSUE ENGINEERING;

EID: 84874221067     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24777     Document Type: Article

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