-
1
-
-
34248659399
-
Carbonic anhydrases as targets for medicinal chemistry
-
Supuran CT, Scozzafava A, (2007) Carbonic anhydrases as targets for medicinal chemistry. Bioorg Med Chem 15: 4336-4350.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 4336-4350
-
-
Supuran, C.T.1
Scozzafava, A.2
-
2
-
-
4344699403
-
Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion
-
Robertson N, Potter C, Harris AL, (2004) Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Res 64: 6160-6165.
-
(2004)
Cancer Res
, vol.64
, pp. 6160-6165
-
-
Robertson, N.1
Potter, C.2
Harris, A.L.3
-
3
-
-
5444223388
-
Expression of carbonic anhydrase IX in mouse tissues
-
Hilvo M, Rafajová M, Pastoreková S, Pastorek J, et al. (2004) Expression of carbonic anhydrase IX in mouse tissues. J Histochem Cytochem 52: 1313-1321.
-
(2004)
J Histochem Cytochem
, vol.52
, pp. 1313-1321
-
-
Hilvo, M.1
Rafajová, M.2
Pastoreková, S.3
Pastorek, J.4
-
4
-
-
44949190364
-
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs
-
Thiry A, Supuran CT, Masereel B, Dogné J-M, (2008) Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs. J Med Chem 51: 3051-3056.
-
(2008)
J Med Chem
, vol.51
, pp. 3051-3056
-
-
Thiry, A.1
Supuran, C.T.2
Masereel, B.3
Dogné, J.-M.4
-
5
-
-
77955296520
-
Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration
-
Chiche J, Ile K, Brahimi-Horn MC, Pouysségur J, (2010) Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration. Adv Enzyme Regul 50: 20-33.
-
(2010)
Adv Enzyme Regul
, vol.50
, pp. 20-33
-
-
Chiche, J.1
Ile, K.2
Brahimi-Horn, M.C.3
Pouysségur, J.4
-
6
-
-
70349490906
-
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
-
Alterio V, Hilvo M, Di Fiore A, Supuran CT, Pan P, et al. (2009) Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. Proc Natl Acad Sci USA 106: 16233-16238.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16233-16238
-
-
Alterio, V.1
Hilvo, M.2
Di Fiore, A.3
Supuran, C.T.4
Pan, P.5
-
7
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wyckoff CC, Beasley NJP, Watson PH, Turner KJ, Pastorek J, et al. (2000) Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 60: 7075-7078.
-
(2000)
Cancer Res
, vol.60
, pp. 7075-7078
-
-
Wyckoff, C.C.1
Beasley, N.J.P.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
-
8
-
-
62749124795
-
Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: a one transcription factor (HIF-1) show?
-
Kaluz S, Kaluzová M, Liao S-Y, Lerman M, et al. (2009) Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: a one transcription factor (HIF-1) show? Biochim Biophys Acta 1795: 162-172.
-
(2009)
Biochim Biophys Acta
, vol.1795
, pp. 162-172
-
-
Kaluz, S.1
Kaluzová, M.2
Liao, S.-Y.3
Lerman, M.4
-
9
-
-
33750050271
-
Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification
-
Hirao M, Tamai N, Tsumaki N, Yoshikawa H, Myoui A, (2006) Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification. J Biol Chem 281: 31079-31092.
-
(2006)
J Biol Chem
, vol.281
, pp. 31079-31092
-
-
Hirao, M.1
Tamai, N.2
Tsumaki, N.3
Yoshikawa, H.4
Myoui, A.5
-
10
-
-
0035499204
-
Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival
-
Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, et al. (2001) Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival. Gene Dev 15: 2865-2876.
-
(2001)
Gene Dev
, vol.15
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
-
11
-
-
24344480012
-
Hypoxia and HIF-1α in chondrogenesis
-
Schipani E, (2005) Hypoxia and HIF-1α in chondrogenesis. Semin Cell Dev Biol 16: 539-546.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 539-546
-
-
Schipani, E.1
-
12
-
-
36549088609
-
HIF1α regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeltogenesis
-
Amarilio R, Viukov SV, Sharir A, Eshkar-Oren I, Johnson RS, et al. (2007) HIF1α regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeltogenesis. Development 134: 3917-3928.
-
(2007)
Development
, vol.134
, pp. 3917-3928
-
-
Amarilio, R.1
Viukov, S.V.2
Sharir, A.3
Eshkar-Oren, I.4
Johnson, R.S.5
-
13
-
-
77955983359
-
Hypoxia, HIFs and bone development
-
Araldi E, Schipani E, (2010) Hypoxia, HIFs and bone development. Bone 47: 190-196.
-
(2010)
Bone
, vol.47
, pp. 190-196
-
-
Araldi, E.1
Schipani, E.2
-
14
-
-
77953208836
-
Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
-
Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, et al. (2010) Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development. Nat Med 16: 678-686.
-
(2010)
Nat Med
, vol.16
, pp. 678-686
-
-
Saito, T.1
Fukai, A.2
Mabuchi, A.3
Ikeda, T.4
Yano, F.5
-
15
-
-
77957748643
-
Carbonic anhydrase II regulates differentiation of ameloblasts via intracellular pH-dependent JNK signaling pathway
-
Wang X, Suzawa T, Ohtsuka H, Zhao B, Miyamoto Y, et al. (2010) Carbonic anhydrase II regulates differentiation of ameloblasts via intracellular pH-dependent JNK signaling pathway. J Cell Physiol 225: 709-719.
-
(2010)
J Cell Physiol
, vol.225
, pp. 709-719
-
-
Wang, X.1
Suzawa, T.2
Ohtsuka, H.3
Zhao, B.4
Miyamoto, Y.5
-
16
-
-
64249126758
-
Expression of transmembrane carbonic anhydrases, CAIX and CAXII, in human development
-
Liao S-Y, Lerman MI, Stanbridge EJ, (2009) Expression of transmembrane carbonic anhydrases, CAIX and CAXII, in human development. BMC Dev Biol 9: 22.
-
(2009)
BMC Dev Biol
, vol.9
, pp. 22
-
-
Liao, S.-Y.1
Lerman, M.I.2
Stanbridge, E.J.3
-
17
-
-
30344480826
-
Elevated expression of hypoxia inducible factor-2α in terminally differentiating growth plate chondrocytes
-
Stewart AJ, Houston B, Farquharson C, (2006) Elevated expression of hypoxia inducible factor-2α in terminally differentiating growth plate chondrocytes. J Cell Physiol 206: 435-440.
-
(2006)
J Cell Physiol
, vol.206
, pp. 435-440
-
-
Stewart, A.J.1
Houston, B.2
Farquharson, C.3
-
18
-
-
0036830491
-
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
-
Akiyama H, Chaboissier M-C, Martin JF, Schedl A, de Crombrugghe B, (2002) The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Gene Dev 16: 2813-2828.
-
(2002)
Gene Dev
, vol.16
, pp. 2813-2828
-
-
Akiyama, H.1
Chaboissier, M.-C.2
Martin, J.F.3
Schedl, A.4
de Crombrugghe, B.5
-
19
-
-
23844493183
-
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9
-
Robins JC, Akeno N, Mukherjee A, Dalal RR, Aronow BJ, et al. (2005) Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone 37: 313-322.
-
(2005)
Bone
, vol.37
, pp. 313-322
-
-
Robins, J.C.1
Akeno, N.2
Mukherjee, A.3
Dalal, R.R.4
Aronow, B.J.5
-
21
-
-
77950345356
-
SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification
-
Hattori T, Müller C, Gebhard S, Bauer E, Pausch F, et al. (2010) SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development 137: 901-911.
-
(2010)
Development
, vol.137
, pp. 901-911
-
-
Hattori, T.1
Müller, C.2
Gebhard, S.3
Bauer, E.4
Pausch, F.5
-
22
-
-
34247477207
-
Hypoxia inducible factor-2α in cancer
-
Löfstedt T, Fredlund E, Holmquist-Mengelbier L, Pietras A, Ovenberger M, et al. (2007) Hypoxia inducible factor-2α in cancer. Cell Cycle 6: 919-926.
-
(2007)
Cell Cycle
, vol.6
, pp. 919-926
-
-
Löfstedt, T.1
Fredlund, E.2
Holmquist-Mengelbier, L.3
Pietras, A.4
Ovenberger, M.5
-
23
-
-
0036720692
-
Cyclic GMP-dependent protein kinase II plays a critical role in C-type natriuretic peptide-mediated endochondral ossification
-
Miyazawa T, Ogawa Y, Chusho H, Yasoda A, Tamura N, et al. (2002) Cyclic GMP-dependent protein kinase II plays a critical role in C-type natriuretic peptide-mediated endochondral ossification. Endocrinology 143: 3604-3610.
-
(2002)
Endocrinology
, vol.143
, pp. 3604-3610
-
-
Miyazawa, T.1
Ogawa, Y.2
Chusho, H.3
Yasoda, A.4
Tamura, N.5
-
24
-
-
4644287296
-
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes
-
Chikuda H, Kugimiya F, Hoshi K, Ikeda T, Ogasawara T, et al. (2004) Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Gene Dev 18: 2418-2429.
-
(2004)
Gene Dev
, vol.18
, pp. 2418-2429
-
-
Chikuda, H.1
Kugimiya, F.2
Hoshi, K.3
Ikeda, T.4
Ogasawara, T.5
-
25
-
-
46749134835
-
Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes
-
Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, et al. (2008) Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes. J Clin Invest 118: 2506-2515.
-
(2008)
J Clin Invest
, vol.118
, pp. 2506-2515
-
-
Kawasaki, Y.1
Kugimiya, F.2
Chikuda, H.3
Kamekura, S.4
Ikeda, T.5
-
26
-
-
0032849244
-
Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells
-
Tintut Y, Parhami F, Le V, Karsenty G, Demer LL, (1999) Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. J Biol Chem 274: 28875-28879.
-
(1999)
J Biol Chem
, vol.274
, pp. 28875-28879
-
-
Tintut, Y.1
Parhami, F.2
Le, V.3
Karsenty, G.4
Demer, L.L.5
-
27
-
-
0034067651
-
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer
-
Huang W, Zhou X, Lefebvre V, de Crombrugghe B, (2000) Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol 20: 4149-4158.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4149-4158
-
-
Huang, W.1
Zhou, X.2
Lefebvre, V.3
de Crombrugghe, B.4
-
28
-
-
0033813919
-
Transcriptional mechanisms of chondrocyte differentiation
-
de Crombrugghe B, Lefebvre V, Behringer RR, Bi W, Murakami S, et al. (2000) Transcriptional mechanisms of chondrocyte differentiation. Matrix Biol 19: 389-394.
-
(2000)
Matrix Biol
, vol.19
, pp. 389-394
-
-
de Crombrugghe, B.1
Lefebvre, V.2
Behringer, R.R.3
Bi, W.4
Murakami, S.5
-
29
-
-
1642545091
-
Essential role of hypertrophic chondrocytes in endochondral bone formation
-
Chung U-I, (2004) Essential role of hypertrophic chondrocytes in endochondral bone formation. Endocrine J 51: 19-24.
-
(2004)
Endocrine J
, vol.51
, pp. 19-24
-
-
Chung, U.-I.1
-
30
-
-
0034024783
-
Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion
-
Závada J, Závadová Z, Pastorek J, Biesová Z, Ježek J, et al. (2000) Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion. Br J Cancer 82: 1808-1813.
-
(2000)
Br J Cancer
, vol.82
, pp. 1808-1813
-
-
Závada, J.1
Závadová, Z.2
Pastorek, J.3
Biesová, Z.4
Ježek, J.5
-
31
-
-
0142121458
-
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin
-
Švastová E, Žilka N, Zat'ovičová M, Gibadulinová A, Čiampor F, et al. (2003) Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin. Exp Cell Res 290: 332-345.
-
(2003)
Exp Cell Res
, vol.290
, pp. 332-345
-
-
Švastová, E.1
Žilka, N.2
Zat'ovičová, M.3
Gibadulinová, A.4
Čiampor, F.5
-
32
-
-
46649107327
-
Inhibition of β-catenin signaling causes defects in postnatal cartilage development
-
Chen M, Zhu M, Awad H Li-F, Sheu T-J, Boyce BF, et al. (2008) Inhibition of β-catenin signaling causes defects in postnatal cartilage development. J Cell Sci 121: 1455-1465.
-
(2008)
J Cell Sci
, vol.121
, pp. 1455-1465
-
-
Chen, M.1
Zhu, M.2
Awad, H.L.-F.3
Sheu, T.-J.4
Boyce, B.F.5
-
33
-
-
57749096407
-
Carbonic anhydrase IX has chaperone-like functions and is an immunoadjuvant
-
Wang Y, Wang X-Y, Subjeck JR, Kim HL, (2008) Carbonic anhydrase IX has chaperone-like functions and is an immunoadjuvant. Mol Cancer Ther 7: 3867-3877.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3867-3877
-
-
Wang, Y.1
Wang, X.-Y.2
Subjeck, J.R.3
Kim, H.L.4
-
35
-
-
24644447079
-
The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin
-
Lilien J, Balsamo J, (2005) The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin. Curr Opin Cell Biol 17: 459-465.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 459-465
-
-
Lilien, J.1
Balsamo, J.2
-
36
-
-
0036006806
-
Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway
-
Sato M, Tanaka T, Maeno T, Sando Y, Suga T, et al. (2002) Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway. Am J Respir Cell Mol Biol 26: 127-134.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 127-134
-
-
Sato, M.1
Tanaka, T.2
Maeno, T.3
Sando, Y.4
Suga, T.5
-
37
-
-
0033584965
-
EPAS1 trans-activation during hypoxia requires p42/p44 MAPK
-
Conrad PW, Freeman TL, Beitner-Johnson D, Millhorn DE, (1999) EPAS1 trans-activation during hypoxia requires p42/p44 MAPK. J Biol Chem 274: 33709-33713.
-
(1999)
J Biol Chem
, vol.274
, pp. 33709-33713
-
-
Conrad, P.W.1
Freeman, T.L.2
Beitner-Johnson, D.3
Millhorn, D.E.4
-
38
-
-
79955399954
-
Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1β via late phase activation of nuclear factor κB and expression of phagocyte-type NADPH oxidase
-
Yoshimura K, Miyamoto Y, Yasuhara R, Maruyama T, Akiyama T, et al. (2011) Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1β via late phase activation of nuclear factor κB and expression of phagocyte-type NADPH oxidase. J Biol Chem 286: 14744-14752.
-
(2011)
J Biol Chem
, vol.286
, pp. 14744-14752
-
-
Yoshimura, K.1
Miyamoto, Y.2
Yasuhara, R.3
Maruyama, T.4
Akiyama, T.5
-
39
-
-
64149097786
-
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
-
Bustin SA, Benes V, Garson JA, Hellemans J, et al. (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.
-
(2009)
Clin Chem
, vol.55
, pp. 611-622
-
-
Bustin, S.A.1
Benes, V.2
Garson, J.A.3
Hellemans, J.4
-
40
-
-
84874132516
-
-
MEPHAS. Available, Accessed 2013 Jan 23
-
MEPHAS. Available: http://www.gen-info.osaka-u.ac.jp/testdocs/tomocom/use-s-d-e.html. Accessed 2013 Jan 23.
-
-
-
-
41
-
-
84907095419
-
R: A language and environment for statistical computing
-
R Core Team, Vienna, Austria,
-
R Core Team (2012) R: A language and environment for statistical computing. R Foundation for Statistical Computing,Vienna, Austria. ISBN 3-900051-07-0, Available: http://www.R-project.org/. Accessed 2013 Jan 23.
-
(2012)
R Foundation for Statistical Computing
-
-
|