Cyclic GMP-dependent protein kinase II plays a critical role in C-type natriuretic peptide-mediated endochondral ossification

Endocrinology

Volumn 143, Issue 9, 2002, Pages 3604-3610

  Miyazawa, Takashi ^a   Ogawa, Yoshihiro ^a   Chusho, Hideki ^a   Yasoda, Akihiro ^a   Tamura, Naohisa ^a   Komatsu, Yasato ^a   Pfeifer, Alexander ^b   Hofmann, Franz ^b   Nakao, Kazuwa ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ION CHANNEL; NATRIURETIC PEPTIDE TYPE C; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE MATRIX; CELL PROLIFERATION; DWARFISM; ENCHONDRAL OSSIFICATION; FETUS; GROWTH PLATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TIBIA;

ANIMALS; ANIMALS, NEWBORN; BONE AND BONES; BONE DEVELOPMENT; CELL DIVISION; CHONDROCYTES; COLLAGEN TYPE X; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DWARFISM; FEMALE; GROWTH PLATE; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NATRIURETIC PEPTIDE, C-TYPE; ORGAN CULTURE TECHNIQUES; OSTEOGENESIS; TIBIA;

EID: 0036720692     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220307     Document Type: Article

References (39)

1. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
2. Decreased bone mass and bone elasticity in mice lacking the transforming growth factor-β1 gene
3. Expression of a truncated, kinase-defective TGF-β type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis
4. Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice
5. Atrial natriuretic factor and related peptide hormones
6. Seminal plasma factors that cause large elevations in cellular cyclic GMP are C-type natriuretic peptides
7. Signal transduction by guanylyl cyclases
8. Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide
9. Differential expression of natriuretic peptide genes in cardiac and extracardiac tissues
10. Two cardiac natriuretic peptide genes (atrial natriuretic peptide and brain natriuretic peptide) are organized in tandem in the mouse and human genomes
11. Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP)
12. Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide
13. C-type natriuretic peptide (CNP) in rats and humans
14. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-β. Possible existence of "vascular natriuretic peptlde system"
15. Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs
16. Dwarfism and early death in mice lacking C-type natriuretic peptide
17. Structure and physiological role of cGMP-dependent protein kinase
18. Structure and function of cyclic nucleotide-dependent protein kinases
19. Intracellular cyclic GMP receptor proteins
20. Alteration of cGMP metabolism during chondrogenic differentiation of chondroprogenitor-like EC cells, ATDC5
21. Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II
22. Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
23. Immunohistochemistry of types I and II collagen in undecalcified skeletal tissues
24. Natriuretic peptide regulation of endochondral ossification. Evidence for possible roles of the C-type natriuretic peptide/guanylyl cyclase-B pathway
25. Regulation of fetal rat bone growth by C-type natriuretic peptide and cGMP
26. Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): Comparison with the human CNP gene (NPPC)
27. Expression of rat cGMP-binding cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development
28. Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene
29. The domain of hypertrophic chondrocytes in growth plates growing at different rates
30. Genetic models reveal that brain natriuretic peptide can signal through different tissue-specific receptor-mediated pathways
31. Defective smooth muscle regulation in cGMP kinase 1-deficient mice
32. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
33. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth
34. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
35. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
36. Collagen types IX and X in the developing chick tibiotarsus: Analyses of mRNAs and proteins
37. Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
38. Effects of cyclic adenosine 3′,5′-monophosphate on chondrocyte terminal differentiation and cartilage-matrix calcification