Synthesis and biological evaluation of novel benzothiazole clubbed fluoroquinolone derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 1, 2013, Pages 1-10

  Sharma, Prabodh Chander ^a   Kumar, Ravinder ^a   Chaudhary, Monika ^a   Sharma, Archana ^a   Rajak, Harish ^b  

^a KURUKSHETRA UNIVERSITY   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Analgesic; Anthelmintic; Anti bacterial; Benzothiazoles; Fluoroquinolones

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 7 [[4 [N (6 NITRO-1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [[4 [N(4,7 DICHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [[4 [N(6 CHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHY]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACIDL; 1 CYCLOPROPYL 6 FLUORO 7 [[4 [N(6 FLUORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 7 [[4 [N(6 METHYL 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 [[3 METHYL 4 [N (4,7 DICHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 [[3 METHYL 4 [N (6 CHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 [[3 METHYL 4 [N (6 FLUORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 [[3 METHYL 4 [N (6 METHYL 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 [[3 METHYL 4 [N (6 NITRO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [[4 [N (6 CHLORO 1,3 BENZOTHIAZOL 2YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [[4 [N (6 FLUORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHY]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [[4 [N(4,7 DICHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL)PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [[4 [N(6 METHYL 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 7 [[4 [N(6 NITRO 1,3 BENZOTHIAZOL 2 YL)AMINO] 2 OXOETHYL]PIPERAZIN 1 YL] 1,4 DIHYDRO 4 OXO QUINOLINE 3 CARBOXYLIC ACID; BENZOTHIAZOLE DERIVATIVE; CIPROFLOXACIN; GATIFLOXACIN; NORFLOXACIN; PIPERAZINE CITRATE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTHELMINTIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; DRUG SYNTHESIS; HUMIDITY; HYDROPHOBICITY; IN VITRO STUDY; LIPID BILAYER; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; NOCICEPTION; NONHUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL; WRITHING TEST;

ANALGESICS; ANIMALS; ANTHELMINTICS; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BENZOTHIAZOLES; CHEMISTRY TECHNIQUES, SYNTHETIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; FEMALE; FLUOROQUINOLONES; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICROBIAL SENSITIVITY TESTS; OLIGOCHAETA; PIPERAZINES; PSEUDOMONAS AERUGINOSA; SPECTROPHOTOMETRY, INFRARED; STAPHYLOCOCCUS AUREUS;

EID: 84874132676     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2011.611943     Document Type: Article

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