메뉴 건너뛰기




Volumn 3, Issue JUN, 2012, Pages

Structural, cellular and molecular aspects of immune privilege in the testis

Author keywords

Immune privilege; Sertoli cell; Testis

Indexed keywords


EID: 84874128482     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2012.00152     Document Type: Review
Times cited : (173)

References (131)
  • 1
    • 0032424386 scopus 로고    scopus 로고
    • Mast cell tryptase stimulates both human dermal fibroblast proliferation and type I collagen production
    • Abe, M., Kurosawa, M., Ishikawa, O. Miyachi, Y., and Kido, H. (1998). Mast cell tryptase stimulates both human dermal fibroblast proliferation and type I collagen production. Clin. Exp. Allergy 28,1509-1517.
    • (1998) Clin. Exp. Allergy , vol.28 , pp. 1509-1517
    • Abe, M.1    Kurosawa, M.2    Ishikawa, O.3    Miyachi, Y.4    Kido, H.5
  • 2
    • 0029003174 scopus 로고
    • Testicular serotonin is related to mast cells but not to Leydig cells in the rat
    • Aguilar, R., Anton, F., Bellido, C., Aguilar, E., and Gaytan, F. (1995). Testicular serotonin is related to mast cells but not to Leydig cells in the rat. J. Endocrinol. 146,15-21.
    • (1995) J. Endocrinol. , vol.146 , pp. 15-21
    • Aguilar, R.1    Anton, F.2    Bellido, C.3    Aguilar, E.4    Gaytan, F.5
  • 3
    • 0030972396 scopus 로고    scopus 로고
    • Transgenic expression of CD95 ligand on islet betacellsinducesagranulocyticinfiltration but does not confer immune privilege upon islet allografts
    • Allison,J.,Georgiou,H. M.,Strasser,A., and Vaux, D. L. (1997). Transgenic expression of CD95 ligand on islet betacellsinducesagranulocyticinfiltration but does not confer immune privilege upon islet allografts. Proc. Natl.Acad.Sci.U.S.A.94,3943-3947.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 3943-3947
    • Allison, J.1    Georgiou, H.M.2    Strasser, A.3    Vaux, D.L.4
  • 4
    • 65649133976 scopus 로고    scopus 로고
    • Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications
    • Andre, S., Tough, D. F., Lacroix-Desmazes,S.,Kaveri,S.V.,and Bayry, J. (2009). Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications. Am. J. Pathol. 174, 1575-1587.
    • (2009) Am. J. Pathol. , vol.174 , pp. 1575-1587
    • Andre, S.1    Tough, D.F.2    Lacroix-Desmazes, S.3    Kaveri, S.V.4    Bayry, J.5
  • 5
    • 0036334812 scopus 로고    scopus 로고
    • Mast cells and fibrosis on testicular biopsies in male infertility
    • Apa, D. D., Cayan, S., Polat, A., and Akbay, E. (2002). Mast cells and fibrosis on testicular biopsies in male infertility. Arch. Androl. 48, 337-344.
    • (2002) Arch. Androl. , vol.48 , pp. 337-344
    • Apa, D.D.1    Cayan, S.2    Polat, A.3    Akbay, E.4
  • 6
    • 0034522512 scopus 로고    scopus 로고
    • Expression and regulation of the CXC-chemokines GRO/KC and IP-10/mob-1 in rat seminiferous tubules
    • Aubry, F., Habasque, C., Satie, A. P., Jegou, B., and Samson, M. (2000). Expression and regulation of the CXC-chemokines, GRO/KC and IP-10/mob-1 in rat seminiferous tubules. Eur. Cytokine Netw. 11, 690-698.
    • (2000) Eur. Cytokine Netw. , vol.11 , pp. 690-698
    • Aubry, F.1    Habasque, C.2    Satie, A.P.3    Jegou, B.4    Samson, M.5
  • 7
    • 0028265488 scopus 로고
    • Expression and regulation of transforming growth factor-beta 1 messenger ribonucleic acid and protein inculturedporcineLeydigandSertoli cells
    • Avallet, O., Vigier, M., Leduque, P., Dubois,P. M.,and Saez,J. M. (1994). Expression and regulation of transforming growth factor-beta 1 mes-senger ribonucleic acid and protein inculturedporcineLeydigandSertoli cells. Endocrinology 134, 2079-2087.
    • (1994) Endocrinology , vol.134 , pp. 2079-2087
    • Avallet, O.1    Vigier, M.2    Leduque, P.3    Dubois, P.M.4    Saez, J.M.5
  • 8
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and Steinman, R. M. (1998). Dendritic cells and the control of immunity. Nature 392, 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 9
    • 0017734968 scopus 로고
    • Immunologically privileged sites
    • Barker, C. F., and Billingham, R. E. (1977). Immunologically privileged sites. Adv. Immunol. 25, 1-54.
    • (1977) Adv. Immunol. , vol.25 , pp. 1-54
    • Barker, C.F.1    Billingham, R.E.2
  • 11
    • 45949104384 scopus 로고    scopus 로고
    • Uropathogenic Escherichia coli block MyD88-dependent and activate MyD88-independent signaling pathways in rat testicular cells
    • Bhushan, S., Tchatalbachev, S., Klug, J., Fijak, M., Pineau, C., Chakraborty, T., and Meinhardt, A. (2008). Uropathogenic Escherichia coli block MyD88-dependent and activate MyD88-independent signaling pathways in rat testicular cells. J. Immunol. 180,5537-5547.
    • (2008) J. Immunol. , vol.180 , pp. 5537-5547
    • Bhushan, S.1    Tchatalbachev, S.2    Klug, J.3    Fijak, M.4    Pineau, C.5    Chakraborty, T.6    Meinhardt, A.7
  • 12
    • 0030601988 scopus 로고    scopus 로고
    • Localization of heat shock proteins in mouse male germ cells:animmunoelectronmicroscopical study
    • Biggiogera, M., Tanguay, R. M., Marin, R., Wu, Y., Martin, T. E., and Fakan,S. (1996). Localization of heat shock proteins in mouse male germ cells:animmunoelectronmicroscopical study. Exp. Cell Res. 229,77-85.
    • (1996) Exp. Cell Res. , vol.229 , pp. 77-85
    • Biggiogera, M.1    Tanguay, R.M.2    Marin, R.3    Wu, Y.4    Martin, T.E.5    Fakan, S.6
  • 13
    • 0018085404 scopus 로고
    • Macrophages, a normal component in seasonally involuting testes of the swan Cygnus olor
    • Breucker, H. (1978). Macrophages, a normal component in seasonally involuting testes of the swan, Cygnus olor. Cell Tissue Res. 193,463-471.
    • (1978) Cell Tissue Res , vol.193 , pp. 463-471
    • Breucker, H.1
  • 14
    • 0037150714 scopus 로고    scopus 로고
    • Germline stem cell transplantation and transgenesis
    • Brinster, R. L. (2002). Germline stem cell transplantation and transgenesis. Science 296,2174-2176.
    • (2002) Science , vol.296 , pp. 2174-2176
    • Brinster, R.L.1
  • 15
    • 71049179042 scopus 로고    scopus 로고
    • FunctionsofTAMRTKsin regulating spermatogenesis and male fertility in mice
    • Chen, Y., Wang, H., Qi, N., Wu, H., Xiong, W., Ma, J., Lu, Q., and Han, D.(2009).FunctionsofTAMRTKsin regulating spermatogenesis and male fertility in mice. Reproduction 138, 655-666.
    • (2009) Reproduction , vol.138 , pp. 655-666
    • Chen, Y.1    Wang, H.2    Qi, N.3    Wu, H.4    Xiong, W.5    Ma, J.6    Lu, Q.7    Han, D.8
  • 16
    • 67649592395 scopus 로고
    • male infertility. Interaction of programmed death-1 and programmed death-1 ligand-1 contributes to testicular immune privilege
    • Cheng, X., Dai, H., Wan, N., Moore, Y., Vankayalapati,R.,and Dai,Z. (2009). male infertility. Interaction of programmed death 1 and programmed death-1 ligand 1 contributes to testicular immune privilege. Transplantation 87, 1778-1786.
    • (1786) Transplantation , vol.87 , pp. 1778-2009
    • Cheng, X.1    Dai, H.2    Wan, N.3    Moore, Y.4    Vankayalapati, R.5    Dai, Z.6
  • 17
    • 0032713707 scopus 로고    scopus 로고
    • Macrophages: important accessory cells for reproductive function
    • Cohen,P.E.,Nishimura,K.,Zhu,L.,and Pollard, J. W. (1999). Macrophages: important accessory cells for reproductive function. J. Leukoc. Biol. 66, 765-772.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 765-772
    • Cohen, P.E.1    Nishimura, K.2    Zhu, L.3    Pollard, J.W.4
  • 19
    • 75649146304 scopus 로고    scopus 로고
    • Androgens in rheumatoid arthritis: when are they effectors?
    • Cutolo, M. (2009). Androgens in rheumatoid arthritis: when are they effectors? Arthritis Res. Ther. 11,126.
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 126
    • Cutolo, M.1
  • 20
    • 4644327279 scopus 로고    scopus 로고
    • Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity
    • Cutolo, M., Sulli, A., Capellino, S., Villaggio, B., Montagna, P., Seri-olo, B., and Straub, R. H. (2004). Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity. Lupus 13, 635-638.
    • (2004) Lupus , vol.13 , pp. 635-638
    • Cutolo, M.1    Sulli, A.2    Capellino, S.3    Villaggio, B.4    Montagna, P.5    Seri-olo, B.6    Straub, R.H.7
  • 23
    • 0027326125 scopus 로고
    • Expression of tumor necrosis factor-alpha in mouse sper-matogenic cells
    • De, S. K., Chen, H. L., Pace, J. L., Hunt, J. S., Terranova, P. F., and Enders, G. C. (1993). Expression of tumor necrosis factor-alpha in mouse sper-matogenic cells. Endocrinology 133, 389-396.
    • (1993) Endocrinology , vol.133 , pp. 389-396
    • De, S.K.1    Chen, H.L.2    Pace, J.L.3    Hunt, J.S.4    Terranova, P.F.5    Enders, G.C.6
  • 25
    • 0031730125 scopus 로고    scopus 로고
    • Expression of interferons-alpha and -gamma in testicular interstitial tis-sue and spermatogonia of the rat
    • Dejucq, N., Lienard, M. O., Guillaume, E., Dorval, I., and Jegou, B. (1998). Expression of interferons-alpha and -gamma in testicular interstitial tis-sue and spermatogonia of the rat. Endocrinology 139,3081-3087.
    • (1998) Endocrinology , vol.139 , pp. 3081-3087
    • Dejucq, N.1    Lienard, M.O.2    Guillaume, E.3    Dorval, I.4    Jegou, B.5
  • 26
  • 27
    • 0037330172 scopus 로고    scopus 로고
    • Immune-endocrine interactions and Leydig cell function: the role of cytokines
    • Diemer, T., Hales, D. B., and Weid-ner, W. (2003). Immune-endocrine interactions and Leydig cell function: the role of cytokines. Andrologia 35, 55-63.
    • (2003) Andrologia , vol.35 , pp. 55-63
    • Diemer, T.1    Hales, D.B.2    Weid-ner, W.3
  • 28
    • 0030807689 scopus 로고    scopus 로고
    • Theeffectsofgonadotropin-releasing hormone immunization and recom-binant follicle-stimulating hormone on the Leydig cell and macrophage populations of the adult rat testis
    • Duckett, R. J., Hedger, M. P., Mclach-lan, R. I., and Wreford, N. G. (1997). Theeffectsofgonadotropin-releasing hormone immunization and recom-binant follicle-stimulating hormone on the Leydig cell and macrophage populations of the adult rat testis. J. Androl. 18,417-423.
    • (1997) J. Androl. , vol.18 , pp. 417-423
    • Duckett, R.J.1    Hedger, M.P.2    Mclach-lan, R.I.3    Wreford, N.G.4
  • 32
    • 33748748036 scopus 로고    scopus 로고
    • The testis in immune privilege
    • Fijak, M., and Meinhardt, A. (2006). The testis in immune privilege. Immunol. Rev. 213, 66-81.
    • (2006) Immunol. Rev. , vol.213 , pp. 66-81
    • Fijak, M.1    Meinhardt, A.2
  • 33
    • 50849143160 scopus 로고    scopus 로고
    • Molecular identification of lyso-glycerophosphocholines as endoge-nous immunosuppressives in bovine and rat gonadal fluids
    • Foulds, L. M., Boysen, R. I., Crane, M., Yang, Y., Muir, J. A., Smith, A. I., De Kretser, D. M., Hearn, M. T., and Hedger, M. P. (2008). Molecular identification of lyso-glycerophosphocholines as endoge-nous immunosuppressives in bovine and rat gonadal fluids. Biol. Reprod. 79,525-536.
    • (2008) Biol. Reprod. , vol.79 , pp. 525-536
    • Foulds, L.M.1    Boysen, R.I.2    Crane, M.3    Yang, Y.4    Muir, J.A.5    Smith, A.I.6    De Kretser, D.M.7    Hearn, M.T.8    Hedger, M.P.9
  • 35
    • 0037069333 scopus 로고    scopus 로고
    • Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma: possible relevance to human fibrotic disorders
    • Frungieri,M.B.,Weidinger,S.,Meineke, V., Köhn, F. M., and Mayerhofer, A. (2002b). Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma: possible relevance to human fibrotic disorders. Proc. Natl. Acad. Sci. U.S.A. 99,15072-15077.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 15072-15077
    • Frungieri, M.B.1    Weidinger, S.2    Meineke, V.3    Köhn, F.M.4    Mayerhofer, A.5
  • 37
    • 0028607072 scopus 로고
    • Require-ment for testicular macrophages in Leydigcellproliferationanddifferen-tiation during prepubertal develop-ment in rats
    • Gaytan, F., Bellido, C., Aguilar, E., and Van Rooijen, N. (1994). Require-ment for testicular macrophages in Leydigcellproliferationanddifferen-tiation during prepubertal develop-ment in rats. J. Reprod. Fertil. 102, 393-399.
    • (1994) J. Reprod. Fertil. , vol.102 , pp. 393-399
    • Gaytan, F.1    Bellido, C.2    Aguilar, E.3    Van Rooijen, N.4
  • 38
    • 0036015694 scopus 로고    scopus 로고
    • The response of testicu-lar leukocytes to lipopolysaccharide-induced inflammation: further evi-dence for heterogeneity of the tes-ticular macrophage population
    • Gerdprasert, O., O'Bryan, M. K., Muir, J. A., Caldwell, A. M., Schlatt, S., De Kretser, D. M., and Hedger, M. P. (2002a). The response of testicu-lar leukocytes to lipopolysaccharide-induced inflammation: further evi-dence for heterogeneity of the tes-ticular macrophage population. Cell Tissue Res. 308,277-285.
    • (2002) Cell Tissue Res , vol.308 , pp. 277-285
    • Gerdprasert, O.1    O'Bryan, M.K.2    Muir, J.A.3    Caldwell, A.M.4    Schlatt, S.5    De Kretser, D.M.6    Hedger, M.P.7
  • 39
    • 0035991077 scopus 로고    scopus 로고
    • Expression of mono-cyte chemoattractant protein-1 and macrophage colony-stimulating fac-tor in normal and inflamed rat testis
    • Gerdprasert, O., O'Bryan, M. K., Nikolic-Paterson, D. J., Sebire, K., De Kretser, D. M., and Hedger, M. P. (2002b). Expression of mono-cyte chemoattractant protein-1 and macrophage colony-stimulating fac-tor in normal and inflamed rat testis. Mol. Hum. Reprod. 8, 518-524.
    • (2002) Mol. Hum. Reprod. , vol.8 , pp. 518-524
    • Gerdprasert, O.1    O'Bryan, M.K.2    Nikolic-Paterson, D.J.3    Sebire, K.4    De Kretser, D.M.5    Hedger, M.P.6
  • 40
    • 68049098297 scopus 로고    scopus 로고
    • Estrogen and testosterone therapies in multiple sclerosis. Prog
    • Gold, S. M., and Voskuhl, R. R. (2009). Estrogen and testosterone therapies in multiple sclerosis. Prog. Brain Res. 175, 239-251.
    • (2009) Brain Res , vol.175 , pp. 239-251
    • Gold, S.M.1    Voskuhl, R.R.2
  • 42
    • 67650841836 scopus 로고    scopus 로고
    • Cytokines and chemokines in testicular inflam-mation: a brief review
    • Guazzone, V. A., Jacobo, P., Theas, M. S., and Lustig, L. (2009). Cytokines and chemokines in testicular inflam-mation: a brief review. Microsc. Res. Tech. 72,620-628.
    • (2009) Microsc. Res. Tech. , vol.72 , pp. 620-628
    • Guazzone, V.A.1    Jacobo, P.2    Theas, M.S.3    Lustig, L.4
  • 43
    • 0345724863 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1/CCL2) in experimental autoim-mune orchitis
    • Guazzone, V. A., Rival, C., Denduchis, B., and Lustig, L. (2003). Monocyte chemoattractant protein-1 (MCP-1/CCL2) in experimental autoim-mune orchitis. J. Reprod. Immunol. 60,143-157.
    • (2003) J. Reprod. Immunol. , vol.60 , pp. 143-157
    • Guazzone, V.A.1    Rival, C.2    Denduchis, B.3    Lustig, L.4
  • 44
    • 33745814436 scopus 로고    scopus 로고
    • Signalling and functional diversity within the Axl subfamily of recep-tor tyrosine kinases
    • Hafizi, S., and Dahlback, B. (2006). Signalling and functional diversity within the Axl subfamily of recep-tor tyrosine kinases. Cytokine Growth Factor Rev. 17,295-304.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 295-304
    • Hafizi, S.1    Dahlback, B.2
  • 45
    • 0028171336 scopus 로고
    • The mature form of interleukin-1 alpha is constitutively expressed in immature male germ cellsfromrat
    • Haugen, T. B., Landmark, B. F., Josef-sen, G. M., Hansson, V., and Hogset, A. (1994). The mature form of interleukin-1 alpha is constitutively expressed in immature male germ cellsfromrat.Mol. Cell. Endocrinol. 105,R19-23.
    • (1994) Mol. Cell. Endocrinol. , vol.105
    • Haugen, T.B.1    Landmark, B.F.2    Josef-sen, G.M.3    Hansson, V.4    Hogset, A.5
  • 46
    • 0021849837 scopus 로고
    • Immune privilege in the testis II. Evaluation of potential local factors
    • Head,J.R.,andBillingham,R.E.(1985). Immune privilege in the testis. II. Evaluation of potential local factors. Transplantation 40,269-275.
    • (1985) Transplantation , vol.40 , pp. 269-275
    • Head, J.R.1    Billingham, R.E.2
  • 47
    • 0021031459 scopus 로고
    • Immune privilege in the testis I. Basic parameters of allograft survival
    • Head, J. R., Neaves, W. B., and Billing-ham, R. E. (1983). Immune privilege in the testis. I. Basic parameters of allograft survival. Transplantation 36, 423-431.
    • (1983) Transplantation , vol.36 , pp. 423-431
    • Head, J.R.1    Neaves, W.B.2    Billing-ham, R.E.3
  • 48
    • 0037206379 scopus 로고    scopus 로고
    • Macrophages and the immune responsiveness of the testis
    • Hedger,M. P. (2002). Macrophages and the immune responsiveness of the testis. J. Reprod. Immunol. 57, 19-34.
    • (2002) J. Reprod. Immunol. , vol.57 , pp. 19-34
    • Hedger, M.P.1
  • 49
    • 79952707343 scopus 로고    scopus 로고
    • Toll-like recep-tors and signalling in spermatogene-sisandtesticularresponsestoinflam-mation-aperspective
    • Hedger, M. P. (2011). Toll-like recep-tors and signalling in spermatogene-sisandtesticularresponsestoinflam-mation-aperspective. J. Reprod. Immunol. 88, 130-141.
    • (2011) J. Reprod. Immunol. , vol.88 , pp. 130-141
    • Hedger, M.P.1
  • 50
    • 0033818075 scopus 로고    scopus 로고
    • Local regulation of T cell numbers and lymphocyte-inhibiting activity in the interstitial tissue of the adult rat testis
    • Hedger, M. P., and Meinhardt, A. (2000). Local regulation of T cell numbers and lymphocyte-inhibiting activity in the interstitial tissue of the adult rat testis. J. Reprod. Immunol. 48, 69-80.
    • (2000) J. Reprod. Immunol. , vol.48 , pp. 69-80
    • Hedger, M.P.1    Meinhardt, A.2
  • 51
    • 0031760446 scopus 로고    scopus 로고
    • Expressionandregula-tion of interferon-gamma-inducible protein 10 gene in rat Leydig cells
    • Hu, J., You, S., Li, W., Wang, D., Nag-pal, M. L., Mi, Y., Liang, P., and Lin,T.(1998).Expressionandregula-tion of interferon-gamma-inducible protein 10 gene in rat Leydig cells. Endocrinology 139,3637-3645.
    • (1998) Endocrinology , vol.139 , pp. 3637-3645
    • Hu, J.1    You, S.2    Li, W.3    Wang, D.4    Nag-pal, M.L.5    Mi, Y.6    Liang, P.7    Lin, T.8
  • 52
    • 18144422479 scopus 로고    scopus 로고
    • Phenotypic characteriza-tion of the immune and mast cell infiltrates in the human testis shows normal and abnormal spermatogen-esis
    • Hussein, M. R., Abou-Deif, E. S., Bedaiwy, M. A., Said, T. M., Mustafa, M.G.,Nada,E.,Ezat,A.,andAgarwal, A. (2005). Phenotypic characteriza-tion of the immune and mast cell infiltrates in the human testis shows normal and abnormal spermatogen-esis. Fertil. Steril. 83,1447-1453.
    • (2005) Fertil. Steril. , vol.83 , pp. 1447-1453
    • Hussein, M.R.1    Abou-Deif, E.S.2    Bedaiwy, M.A.3    Said, T.M.4    Mustafa, M.G.5    Nada, E.6    Ezat, A.7    Agarwal, A.8
  • 53
    • 30344442114 scopus 로고    scopus 로고
    • Physiologic inter-actions between macrophages and Leydig cells
    • Hutson, J. C. (2006). Physiologic inter-actions between macrophages and Leydig cells. Exp. Biol. Med. (May-wood) 231,1-7.
    • (2006) Exp. Biol. Med. (May-wood) , vol.231 , pp. 1-7
    • Hutson, J.C.1
  • 55
    • 26244442091 scopus 로고    scopus 로고
    • Tissuemicrocircumstancesforleuko-cytic infiltration into the testis and epididymis in mice
    • Itoh, M., Terayama, H., Naito, M., Ogawa, Y., and Tainosho, S. (2005). Tissuemicrocircumstancesforleuko-cytic infiltration into the testis and epididymis in mice. J. Reprod. Immunol. 67, 57-67.
    • (2005) J. Reprod. Immunol. , vol.67 , pp. 57-67
    • Itoh, M.1    Terayama, H.2    Naito, M.3    Ogawa, Y.4    Tainosho, S.5
  • 56
    • 67649743418 scopus 로고    scopus 로고
    • Differential changes in CD4+ and CD8+ effector and reg-ulatory T lymphocyte subsets in the testisofratsundergoingautoimmune orchitis
    • Jacobo, P., Guazzone, V. A., Jarazo-Dietrich, S., Theas, M. S., and Lustig, L. (2009). Differential changes in CD4+ and CD8+ effector and reg-ulatory T lymphocyte subsets in the testisofratsundergoingautoimmune orchitis. J. Reprod. Immunol. 81, 44-54.
    • (2009) J. Reprod. Immunol. , vol.81 , pp. 44-54
    • Jacobo, P.1    Guazzone, V.A.2    Jarazo-Dietrich, S.3    Theas, M.S.4    Lustig, L.5
  • 57
    • 18244363854 scopus 로고    scopus 로고
    • Bioactivity of androgens within the testes and serum of normal men
    • Jarow, J. P., Wright, W. W., Brown, T. R., Yan, X., and Zirkin, B. R. (2005). Bioactivity of androgens within the testes and serum of normal men. J. Androl. 26,343-348.
    • (2005) J. Androl. , vol.26 , pp. 343-348
    • Jarow, J.P.1    Wright, W.W.2    Brown, T.R.3    Yan, X.4    Zirkin, B.R.5
  • 59
    • 0028997664 scopus 로고
    • Indomethacin blocks the immuno-suppressive activity of rat testicular macrophages cultured in vitro
    • Kern, S., and Maddocks, S. (1995). Indomethacin blocks the immuno-suppressive activity of rat testicular macrophages cultured in vitro. J. Reprod. Immunol. 28,189-201.
    • (1995) J. Reprod. Immunol. , vol.28 , pp. 189-201
    • Kern, S.1    Maddocks, S.2
  • 60
    • 0028810478 scopus 로고
    • Cytokinesecre-tion by macrophages in the rat testis
    • Kern,S.,Robertson,S.A.,Mau,V.J.,and Maddocks,S.(1995). Cytokinesecre-tion by macrophages in the rat testis. Biol. Reprod. 53, 1407-1416.
    • (1995) Biol. Reprod. , vol.53 , pp. 1407-1416
    • Kern, S.1    Robertson, S.A.2    Mau, V.J.3    Maddocks, S.4
  • 61
    • 0034048740 scopus 로고    scopus 로고
    • Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice
    • Korbutt, G. S., Suarez-Pinzon, W. L., Power, R. F., Rajotte, R. V., and Rabinovitch, A. (2000). Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice. Diabetologia 43,474-480.
    • (2000) Diabetologia , vol.43 , pp. 474-480
    • Korbutt, G.S.1    Suarez-Pinzon, W.L.2    Power, R.F.3    Rajotte, R.V.4    Rabinovitch, A.5
  • 62
    • 0024427107 scopus 로고
    • Transplantation of newborn rat testis under the kidney capsule of adult host as a model to study the struc-ture and function of Leydig cells
    • Kuopio, T., Savouras, P. O., Pelliniemi, L. J., and Huhtaniemi, I. T. (1989). Transplantation of newborn rat testis under the kidney capsule of adult host as a model to study the struc-ture and function of Leydig cells. J. Androl. 10,335-345.
    • (1989) J. Androl. , vol.10 , pp. 335-345
    • Kuopio, T.1    Savouras, P.O.2    Pelliniemi, L.J.3    Huhtaniemi, I.T.4
  • 64
    • 42649140235 scopus 로고    scopus 로고
    • Immunobiology of the TAM recep-tors
    • Lemke, G., and Rothlin, C. V. (2008). Immunobiology of the TAM recep-tors. Nat. Rev. Immunol. 8, 327-336.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 327-336
    • Lemke, G.1    Rothlin, C.V.2
  • 66
    • 0027433606 scopus 로고
    • Phenotypic characterization of lymphocytic cell infiltratesintothetestesofratsunder-going autoimmune orchitis
    • Lustig, L., Lourtau, L., Perez, R., and Doncel, G. F. (1993). Phenotypic characterization of lymphocytic cell infiltratesintothetestesofratsunder-going autoimmune orchitis. Int. J. Androl. 16,279-284.
    • (1993) Int. J. Androl. , vol.16 , pp. 279-284
    • Lustig, L.1    Lourtau, L.2    Perez, R.3    Doncel, G.F.4
  • 67
    • 4444361374 scopus 로고    scopus 로고
    • Spermato-genesis following syngeneic testicu-lar transplantation in Balb/c mice
    • Ma, P., Ge, Y., Wang, S., Ma, J., Xue, S., and Han, D. (2004). Spermato-genesis following syngeneic testicu-lar transplantation in Balb/c mice. Reproduction 128, 163-170.
    • (2004) Reproduction , vol.128 , pp. 163-170
    • Ma, P.1    Ge, Y.2    Wang, S.3    Ma, J.4    Xue, S.5    Han, D.6
  • 68
    • 0029997493 scopus 로고    scopus 로고
    • Peritubularmyoid cells in the testis: their structure and function
    • Maekawa, M., Kamimura, K., and Nagano,T.(1996).Peritubularmyoid cells in the testis: their structure and function. Arch.Histol.Cytol.59, 1-13.
    • (1996) Arch. Histol. Cytol. 59 , pp. 1-13
    • Maekawa, M.1    Kamimura, K.2    Nagano, T.3
  • 70
    • 0031948132 scopus 로고    scopus 로고
    • Local regulation of macrophage subsets in the adult rat testis: examination of the roles of the seminiferous tubules, testos-terone, and macrophage-migration inhibitory factor
    • Meinhardt, A., Bacher, M., Metz, C., Bucala, R., Wreford, N., Lan, H., Atkins, R., and Hedger, M. (1998). Local regulation of macrophage subsets in the adult rat testis: examination of the roles of the seminiferous tubules, testos-terone, and macrophage-migration inhibitory factor. Biol. Reprod. 59, 371-378.
    • (1998) Biol. Reprod. , vol.59 , pp. 371-378
    • Meinhardt, A.1    Bacher, M.2    Metz, C.3    Bucala, R.4    Wreford, N.5    Lan, H.6    Atkins, R.7    Hedger, M.8
  • 71
    • 79951577615 scopus 로고    scopus 로고
    • Immunological, paracrine and endocrine aspects of testicu-lar immune privilege
    • Meinhardt, A., and Hedger, M. P. (2011). Immunological, paracrine and endocrine aspects of testicu-lar immune privilege. Mol. Cell. Endocrinol. 335,60-68.
    • (2011) Mol. Cell. Endocrinol. , vol.335 , pp. 60-68
    • Meinhardt, A.1    Hedger, M.P.2
  • 73
    • 33748744234 scopus 로고    scopus 로고
    • Immune privilege: a recurrent theme inimmunoregulation
    • Mellor, A. L., and Munn, D. H. (2006). Immune privilege: a recurrent theme inimmunoregulation. Immunol. Rev. 213,5-11.
    • (2006) Immunol. Rev. , vol.213 , pp. 5-11
    • Mellor, A.L.1    Munn, D.H.2
  • 74
    • 80052550535 scopus 로고    scopus 로고
    • Sertoli cell-specific deletion of the andro-gen receptor compromises testicu-lar immune privilege in mice
    • Meng, J., Greenlee, A. R., Taub, C. J., and Braun, R. E. (2011). Sertoli cell-specific deletion of the andro-gen receptor compromises testicu-lar immune privilege in mice. Biol. Reprod. 85,254-260.
    • (2011) Biol. Reprod. , vol.85 , pp. 254-260
    • Meng, J.1    Greenlee, A.R.2    Taub, C.J.3    Braun, R.E.4
  • 76
    • 0347122087 scopus 로고    scopus 로고
    • Hsp70 pro-motes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo
    • Millar, D. G., Garza, K. M., Odermatt, B., Elford, A. R., Ono, N., Li, Z., and Ohashi, P. S. (2003). Hsp70 pro-motes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo. Nat. Med. 9, 1469-1476.
    • (2003) Nat. Med. , vol.9 , pp. 1469-1476
    • Millar, D.G.1    Garza, K.M.2    Odermatt, B.3    Elford, A.R.4    Ono, N.5    Li, Z.6    Ohashi, P.S.7
  • 77
    • 79956267665 scopus 로고    scopus 로고
    • The blood-testis and blood-epididymis barriers are more than just their tight junctions
    • Mital, P., Hinton, B. T., and Dufour, J. M. (2011). The blood-testis and blood-epididymis barriers are more than just their tight junctions. Biol. Reprod. 84,851-858.
    • (2011) Biol. Reprod. , vol.84 , pp. 851-858
    • Mital, P.1    Hinton, B.T.2    Dufour, J.M.3
  • 78
    • 3042706568 scopus 로고    scopus 로고
    • Phagocytic removal of apop-totic spermatogenic cells by Sertoli cells: mechanisms and consequences
    • Nakanishi, Y., and Shiratsuchi, A. (2004). Phagocytic removal of apop-totic spermatogenic cells by Sertoli cells: mechanisms and consequences. Biol. Pharm. Bull. 27,13-16.
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 13-16
    • Nakanishi, Y.1    Shiratsuchi, A.2
  • 79
    • 18644381515 scopus 로고    scopus 로고
    • Testicular immune privi-lege promotes transplantation toler-ance by altering the balance between memory and regulatory T cells
    • Nasr, I. W., Wang, Y., Gao, G., Deng, S., Diggs, L., Rothstein, D. M., Tel-lides, G., Lakkis, F. G., and Dai, Z. (2005). Testicular immune privi-lege promotes transplantation toler-ance by altering the balance between memory and regulatory T cells. J. Immunol. 174,6161-6168.
    • (2005) J. Immunol. , vol.174 , pp. 6161-6168
    • Nasr, I.W.1    Wang, Y.2    Gao, G.3    Deng, S.4    Diggs, L.5    Rothstein, D.M.6    Tel-lides, G.7    Lakkis, F.G.8    Dai, Z.9
  • 82
    • 64149101819 scopus 로고    scopus 로고
    • Defects in the regulatory clearance mechanisms favor the breakdown of self-tolerance during spontaneous autoimmune orchitis
    • Pelletier, R. M., Yoon, S. R., Akpovi, C. D.,Silvas,E.,andVitale,M.L.(2009). Defects in the regulatory clearance mechanisms favor the breakdown of self-tolerance during spontaneous autoimmune orchitis. Am. J. Phys-iol. Regul. Integr. Comp. Physiol. 296, R743-R762.
    • (2009) Am. J. Phys-iol. Regul. Integr. Comp. Physiol. , vol.296
    • Pelletier, R.M.1    Yoon, S.R.2    Akpovi, C.D.3    Silvas, E.4    Vitale, M.L.5
  • 84
    • 77955383770 scopus 로고    scopus 로고
    • DAMPening inflamma-tion by modulating TLR signalling
    • Piccinini, A. M., and Midwood, K. S. (2010). DAMPening inflamma-tion by modulating TLR signalling. Mediat. Inflamm. 2010, 672395.
    • (2010) Mediat. Inflamm. , vol.2010 , pp. 672395
    • Piccinini, A.M.1    Midwood, K.S.2
  • 88
    • 40949103883 scopus 로고    scopus 로고
    • Testos-terone reduces macrophage expres-sioninthemouseof toll-likereceptor 4, a trigger for inflammation and innate immunity
    • Rettew, J. A., Huet-Hudson, Y. M., and Marriott, I. (2008). Testos-terone reduces macrophage expres-sioninthemouseof toll-likereceptor 4, a trigger for inflammation and innate immunity. Biol. Reprod. 78, 432-437.
    • (2008) Biol. Reprod. , vol.78 , pp. 432-437
    • Rettew, J.A.1    Huet-Hudson, Y.M.2    Marriott, I.3
  • 90
    • 33646381130 scopus 로고    scopus 로고
    • Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis
    • Rival, C., Theas, M. S., Guazzone, V. A.,and Lustig,L.(2006). Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis. J. Reprod. Immunol. 70, 43-58.
    • (2006) J. Reprod. Immunol. , vol.70 , pp. 43-58
    • Rival, C.1    Theas, M.S.2    Guazzone, V.A.3    Lustig, L.4
  • 91
    • 44649103840 scopus 로고    scopus 로고
    • Functional andphenotypiccharacteristicsof tes-ticular macrophages in experimental autoimmune orchitis
    • Rival, C., Theas, M. S., Suescun, M. O., Jacobo,P.,Guazzone,V.,VanRooijen, N., and Lustig, L. (2008). Functional andphenotypiccharacteristicsof tes-ticular macrophages in experimental autoimmune orchitis. J. Pathol. 215, 108-117.
    • (2008) J. Pathol. , vol.215 , pp. 108-117
    • Rival, C.1    Theas, M.S.2    Suescun, M.O.3    Jacobo, P.4    Guazzone, V.5    VanRooijen, N.6    Lustig, L.7
  • 92
    • 36849033963 scopus 로고    scopus 로고
    • TAM recep-tors are pleiotropic inhibitors of the innate immune response
    • Rothlin, C. V., Ghosh, S., Zuniga, E. I., Oldstone, M. B., and Lemke, G. (2007). TAM recep-tors are pleiotropic inhibitors of the innate immune response. Cell 131, 1124-1136.
    • (2007) Cell , vol.131 , pp. 1124-1136
    • Rothlin, C.V.1    Ghosh, S.2    Zuniga, E.I.3    Oldstone, M.B.4    Lemke, G.5
  • 93
    • 25144452923 scopus 로고    scopus 로고
    • Con-tinuous control of autoimmune dis-easebyantigen-dependentpolyclonal CD4+CD25+ regulatory T cells in theregionallymphnode
    • Samy, E. T., Parker, L. A., Sharp, C. P., and Tung, K. S. (2005). Con-tinuous control of autoimmune dis-easebyantigen-dependentpolyclonal CD4+CD25+ regulatory T cells in theregionallymphnode.J.Exp.Med. 202,771-781.
    • (2005) J. Exp. Med. , vol.202 , pp. 771-781
    • Samy, E.T.1    Parker, L.A.2    Sharp, C.P.3    Tung, K.S.4
  • 94
    • 0029844911 scopus 로고    scopus 로고
    • Testis-derived Sertoli cells survive and pro-vide localized immunoprotection for xenografts in rat brain
    • Sanberg,P.R.,Borlongan,C.V.,Saporta, S.,and Cameron,D. F. (1996). Testis-derived Sertoli cells survive and pro-vide localized immunoprotection for xenografts in rat brain. Nat. Biotech-nol. 14,1692-1695.
    • (1996) Nat. Biotech-nol. , vol.14 , pp. 1692-1695
    • Sanberg, P.R.1    Borlongan, C.V.2    Saporta, S.3    Cameron, D.F.4
  • 96
    • 40949162305 scopus 로고    scopus 로고
    • Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat
    • Sarkar, O., Mathur, P. P., Cheng, C. Y., and Mruk, D. D. (2008). Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat. Biol. Reprod. 78, 445-454.
    • (2008) Biol. Reprod. , vol.78 , pp. 445-454
    • Sarkar, O.1    Mathur, P.P.2    Cheng, C.Y.3    Mruk, D.D.4
  • 97
    • 41549144843 scopus 로고    scopus 로고
    • Exploring human testicular peritubular cells: identification of secretory products and regulation by tumor necro-sis factor-alpha
    • Schell, C., Albrecht, M., Mayer, C., Schwarzer, J. U., Frungieri, M. B., andMayerhofer,A.(2008).Exploring human testicular peritubular cells: identification of secretory products and regulation by tumor necro-sis factor-alpha. Endocrinology 149, 1678-1686.
    • (2008) Endocrinology , vol.149 , pp. 1678-1686
    • Schell, C.1    Albrecht, M.2    Mayer, C.3    Schwarzer, J.U.4    Frungieri, M.B.5    Mayerhofer, A.6
  • 98
    • 32944465442 scopus 로고    scopus 로고
    • Immune privilege and inflammation of the testis
    • Schuppe, H. C., and Meinhardt, A. (2005). Immune privilege and inflammation of the testis. Chem. Immunol. Allergy 88,1-14.
    • (2005) Chem. Immunol. Allergy , vol.88 , pp. 1-14
    • Schuppe, H.C.1    Meinhardt, A.2
  • 101
    • 0027167697 scopus 로고
    • Sertolicell-enrichedfractions insuccessfulisletcelltransplantation
    • Selawry, H. P., and Cameron, D. F. (1993).Sertolicell-enrichedfractions insuccessfulisletcelltransplantation. Cell Transplant. 2, 123-129.
    • (1993) Cell Transplant , vol.2 , pp. 123-129
    • Selawry, H.P.1    Cameron, D.F.2
  • 102
    • 2942627626 scopus 로고    scopus 로고
    • Hydrophobicity: an ancient damage-associatedmolecularpatternthatini-tiates innate immune responses
    • Seong, S. Y., and Matzinger, P. (2004). Hydrophobicity: an ancient damage-associatedmolecularpatternthatini-tiates innate immune responses. Nat. Rev. Immunol. 4, 469-478.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 469-478
    • Seong, S.Y.1    Matzinger, P.2
  • 103
    • 0024987612 scopus 로고
    • The testis and tissue transplantation: historical aspects
    • Setchell, B. P. (1990). The testis and tissue transplantation: historical aspects. J. Reprod. Immunol. 18,1-8.
    • (1990) J. Reprod. Immunol. , vol.18 , pp. 1-8
    • Setchell, B.P.1
  • 104
    • 0028895664 scopus 로고
    • Failure of thyroid allo-grafts to function in the testes of cynomolgous monkeys
    • Setchell,B.P.,Granholm,T.,andRitzen, E. M. (1995). Failure of thyroid allo-grafts to function in the testes of cynomolgous monkeys. J. Reprod. Immunol. 28, 75-80.
    • (1995) J. Reprod. Immunol. , vol.28 , pp. 75-80
    • Setchell, B.P.1    Granholm, T.2    Ritzen, E.M.3
  • 105
    • 79959401429 scopus 로고    scopus 로고
    • Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells
    • Shang, T., Zhang, X., Wang, T., Sun, B., Deng, T., and Han, D. (2011). Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells. Endocrinology 152,2827-2836.
    • (2011) Endocrinology , vol.152 , pp. 2827-2836
    • Shang, T.1    Zhang, X.2    Wang, T.3    Sun, B.4    Deng, T.5    Han, D.6
  • 106
    • 33748749509 scopus 로고    scopus 로고
    • A historical per-spective on immunological privilege
    • Simpson, E. (2006). A historical per-spective on immunological privilege. Immunol. Rev. 213, 12-22.
    • (2006) Immunol. Rev. , vol.213 , pp. 12-22
    • Simpson, E.1
  • 108
    • 0023930756 scopus 로고
    • Fetal and postnatal testis shows immuno-privilege as donor tissue
    • Statter, M. B., Foglia, R. P., Parks, D. E., and Donahoe, P. K. (1988). Fetal and postnatal testis shows immuno-privilege as donor tissue. J. Urol. 139, 204-210.
    • (1988) J. Urol. , vol.139 , pp. 204-210
    • Statter, M.B.1    Foglia, R.P.2    Parks, D.E.3    Donahoe, P.K.4
  • 109
    • 79951778173 scopus 로고    scopus 로고
    • Drug transporters, the blood-testis barrier, and sper-matogenesis
    • Su, L., Mruk, D. D., and Cheng, C. Y. (2011). Drug transporters, the blood-testis barrier, and sper-matogenesis. J. Endocrinol. 208, 207-223.
    • (2011) J. Endocrinol. , vol.208 , pp. 207-223
    • Su, L.1    Mruk, D.D.2    Cheng, C.Y.3
  • 110
    • 0033765669 scopus 로고    scopus 로고
    • Testicu-lar sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism
    • Suarez-Pinzon, W., Korbutt, G. S., Power, R., Hooton, J., Rajotte, R. V., and Rabinovitch, A. (2000). Testicu-lar sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism. Diabetes 49,1810-1818.
    • (2000) Diabetes , vol.49 , pp. 1810-1818
    • Suarez-Pinzon, W.1    Korbutt, G.S.2    Power, R.3    Hooton, J.4    Rajotte, R.V.5    Rabinovitch, A.6
  • 111
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda, T., Takahashi, T., Golstein, P., and Nagata, S. (1993). Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75,1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 112
    • 77954505329 scopus 로고    scopus 로고
    • Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors
    • Sun,B.,Qi,N.,Shang,T.,Wu,H.,Deng, T., and Han, D. (2010). Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors. Endocrinology 151,2886-2897.
    • (2010) Endocrinology , vol.151 , pp. 2886-2897
    • Sun, B.1    Qi, N.2    Shang, T.3    Wu, H.4    Deng, T.5    Han, D.6
  • 113
    • 12444341944 scopus 로고    scopus 로고
    • Toll-likereceptorsininnateimmunity
    • Takeda, K., and Akira, S. (2005). Toll-likereceptorsininnateimmunity.Int. Immunol. 17,1-14.
    • (2005) Int. Immunol. , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 116
    • 47649107396 scopus 로고    scopus 로고
    • Tumour necro-sis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis
    • Theas, M. S., Rival, C., Jarazo-Dietrich, S., Jacobo, P., Guazzone, V. A., and Lustig, L. (2008). Tumour necro-sis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis. Hum. Reprod. 23, 1865-1872.
    • (2008) Hum. Reprod. , vol.23 , pp. 1865-1872
    • Theas, M.S.1    Rival, C.2    Jarazo-Dietrich, S.3    Jacobo, P.4    Guazzone, V.A.5    Lustig, L.6
  • 117
    • 0038703058 scopus 로고    scopus 로고
    • Germ cell apoptosis in autoimmuneorchitis:involvementof the Fas-FasL system
    • Theas, S., Rival, C., and Lustig, L. (2003). Germ cell apoptosis in autoimmuneorchitis:involvementof the Fas-FasL system. Am. J. Reprod. Immunol. 50, 166-176.
    • (2003) Am. J. Reprod. Immunol. , vol.50 , pp. 166-176
    • Theas, S.1    Rival, C.2    Lustig, L.3
  • 118
    • 0019395392 scopus 로고
    • Autoimmunity to sperma-tozoa and the testis
    • Tung, K. S., Teuscher, C., and Meng, A. L. (1981). Autoimmunity to sperma-tozoa and the testis. Immunol. Rev. 55,217-255.
    • (1981) Immunol. Rev. , vol.55 , pp. 217-255
    • Tung, K.S.1    Teuscher, C.2    Meng, A.L.3
  • 119
    • 0035903158 scopus 로고    scopus 로고
    • Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1receptorsignalingpathwayininnate immune cells
    • Vabulas, R. M., Ahmad-Nejad, P., Da Costa, C., Miethke, T., Kirschn-ing, C. J., Hacker, H., and Wag-ner, H. (2001). Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1receptorsignalingpathwayininnate immune cells. J. Biol. Chem. 276, 31332-31339.
    • (2001) J. Biol. Chem , vol.276 , pp. 31332-31339
    • Vabulas, R.M.1    Ahmad-Nejad, P.2    Da Costa, C.3    Miethke, T.4    Kirschn-ing, C.J.5    Hacker, H.6    Wag-ner, H.7
  • 120
    • 0033951678 scopus 로고    scopus 로고
    • Peritubular cell-Sertoli cell interactions: factors involved in PmodS activity
    • Verhoeven, G., Hoeben, E., and De Gendt, K. (2000). Peritubular cell-Sertoli cell interactions: factors involved in PmodS activity. Androlo-gia 32, 42-45.
    • (2000) Androlo-gia , vol.32 , pp. 42-45
    • Verhoeven, G.1    Hoeben, E.2    De Gendt, K.3
  • 121
    • 27244442563 scopus 로고    scopus 로고
    • Immunoexpression of Tyro 3 family receptors -Tyro 3, Axl, and Mer -and their ligand Gas6 in postnatal developing mouse testis
    • Wang, H., Chen, Y., Ge, Y., Ma, P., Ma, Q., Ma, J., Xue, S., and Han, D. (2005). Immunoexpression of Tyro 3 family receptors -Tyro 3, Axl, and Mer -and their ligand Gas6 in postnatal developing mouse testis. J. Histochem.Cytochem. 53, 1355-1364.
    • (2005) J. Histochem. Cytochem. , vol.53 , pp. 1355-1364
    • Wang, H.1    Chen, Y.2    Ge, Y.3    Ma, P.4    Ma, Q.5    Ma, J.6    Xue, S.7    Han, D.8
  • 122
    • 84864018112 scopus 로고    scopus 로고
    • Toll-like recep-tor 3-initiated antiviral responses in mouse male germ cells in vitro
    • Wang,T.,Zhang,X.,Chen,Q.,Deng,T., Zhang, Y., Li, N., Shang, T., Chen, Y., and Han, D. (2012). Toll-like recep-tor 3-initiated antiviral responses in mouse male germ cells in vitro. Biol. Reprod. 86,1-10.
    • (2012) Biol. Reprod. , vol.86 , pp. 1-10
    • Wang, T.1    Zhang, X.2    Chen, Q.3    Deng, T.4    Zhang, Y.5    Li, N.6    Shang, T.7    Chen, Y.8    Han, D.9
  • 123
    • 20844454161 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated human IL-10 gene transfer suppresses the development of experimental autoimmune orchi-tis
    • Watanabe, M., Kashiwakura, Y., Kusumi, N., Tamayose, K., Nasu, Y., Nagai,A.,Shimada,T.,Daida,H.,and Kumon,H.(2005).Adeno-associated virus-mediated human IL-10 gene transfer suppresses the development of experimental autoimmune orchi-tis. Gene Ther. 12,1126-1132.
    • (2005) Gene Ther , vol.12 , pp. 1126-1132
    • Watanabe, M.1    Kashiwakura, Y.2    Kusumi, N.3    Tamayose, K.4    Nasu, Y.5    Nagai, A.6    Shimada, T.7    Daida, H.8    Kumon, H.9
  • 124
    • 66649102550 scopus 로고    scopus 로고
    • Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells andactivatesneutrophilsviaToll-like receptor (TLR)-4
    • Wheeler, D. S., Chase, M. A., Senft, A. P., Poynter, S. E., Wong, H. R., and Page, K. (2009). Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells andactivatesneutrophilsviaToll-like receptor (TLR)-4. Respir. Res. 10,31.
    • (2009) Respir. Res , vol.10 , pp. 31
    • Wheeler, D.S.1    Chase, M.A.2    Senft, A.P.3    Poynter, S.E.4    Wong, H.R.5    Page, K.6
  • 126
    • 79951685364 scopus 로고    scopus 로고
    • Differential responses of epithelial Sertoli cells of the rat testis to Toll-like receptor 2 and 4 lig-ands: implications for studies of tes-ticular inflammation using bacterial lipopolysaccharides
    • Winnall, W. R., Muir, J. A., and Hedger, M. P. (2011). Differential responses of epithelial Sertoli cells of the rat testis to Toll-like receptor 2 and 4 lig-ands: implications for studies of tes-ticular inflammation using bacterial lipopolysaccharides. Innate Immun. 17,123-136.
    • (2011) Innate Immun , vol.17 , pp. 123-136
    • Winnall, W.R.1    Muir, J.A.2    Hedger, M.P.3
  • 127
    • 50449105168 scopus 로고    scopus 로고
    • Expression patterns and functions of toll-like receptors in mouse sertoli cells
    • Wu, H., Wang, H., Xiong, W., Chen, S., Tang, H., and Han, D. (2008). Expression patterns and functions of toll-like receptors in mouse sertoli cells. Endocrinology 149, 4402-4412.
    • (2008) Endocrinology , vol.149 , pp. 4402-4412
    • Wu, H.1    Wang, H.2    Xiong, W.3    Chen, S.4    Tang, H.5    Han, D.6
  • 128
    • 0023753012 scopus 로고
    • Suppression of lympho-cyteproliferationbyproteinssecreted by cultured Sertoli cells
    • Wyatt, C. R., Law, L., Magnuson, J. A., Griswold, M. D., and Magnuson, N. S. (1988). Suppression of lympho-cyteproliferationbyproteinssecreted by cultured Sertoli cells. J. Reprod. Immunol. 14, 27-40.
    • (1988) J. Reprod. Immunol. , vol.14 , pp. 27-40
    • Wyatt, C.R.1    Law, L.2    Magnuson, J.A.3    Griswold, M.D.4    Magnuson, N.S.5
  • 129
    • 0027135495 scopus 로고
    • Expression, regulation, and pro-duction of tumor necrosis factor-alpha in mouse testicular interstitial macrophages in vitro
    • Xiong, Y., and Hales, D. B. (1993). Expression, regulation, and pro-duction of tumor necrosis factor-alpha in mouse testicular interstitial macrophages in vitro. Endocrinology 133,2568-2573.
    • (1993) Endocrinology , vol.133 , pp. 2568-2573
    • Xiong, Y.1    Hales, D.B.2
  • 130
    • 0023676206 scopus 로고
    • Autoantigenic germ cells exist outside the blood testis barrier
    • Yule, T. D., Montoya, G. D., Russell, L. D., Williams, T. M., and Tung, K. S. (1988). Autoantigenic germ cells exist outside the blood testis barrier. J. Immunol. 141,1161-1167.
    • (1988) J. Immunol. , vol.141 , pp. 1161-1167
    • Yule, T.D.1    Montoya, G.D.2    Russell, L.D.3    Williams, T.M.4    Tung, K.S.5
  • 131
    • 33750031603 scopus 로고    scopus 로고
    • The high mobil-ity group box chromosomal protein 1 is expressed in the human and rat testis where it may function as an antibacterialfactor
    • Zetterstrom, C. K., Strand, M. L., and Soder, O. (2006). The high mobil-ity group box chromosomal protein 1 is expressed in the human and rat testis where it may function as an antibacterialfactor. Hum. Reprod. 21, 2801-2809.
    • (2006) Hum. Reprod. , vol.21 , pp. 2801-2809
    • Zetterstrom, C.K.1    Strand, M.L.2    Soder, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.