Oxysterols modulate calcium signalling in the A7r5 aortic smooth muscle cell-line

Biochimie

Volumn 95, Issue 3, 2013, Pages 568-577

  Hammoud, Yzzam ^a   Rice, Tom ^a   MacKrill, John J ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Atherosclerosis; Calcium; Inositol 1,4,5 trisphosphate receptor; Oxysterol; Ryanodine receptor; Smooth muscle

Indexed keywords

7BETA HYDROXYCHOLESTEROL; ARGIPRESSIN; BRADYKININ; CALCIUM ION; CHLOROCRESOL; CHOLESTEROL; EPOXOMICIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; OXYSTEROL; PROTEASOME; RYANODINE RECEPTOR 1; THAPSIGARGIN; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; AORTA; ARTERY MUSCLE; ARTICLE; ATHEROSCLEROSIS; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ENDOPLASMIC RETICULUM; EXPERIMENTAL MODEL; EXPOSURE; NONHUMAN; PROTEIN DEGRADATION; RAT; RECEPTOR DOWN REGULATION; SMOOTH MUSCLE FIBER; TIME;

ANIMALS; AORTA; CALCIUM SIGNALING; CELL LINE; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HYDROXYCHOLESTEROLS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MUSCLE, SMOOTH, VASCULAR; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RATS; TIME FACTORS;

EID: 84874111645     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.08.003     Document Type: Article

References (36)

1. A. Vejux, L. Malvitte, and G. Lizard Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis Braz. J. Med. Biol. Res. 41 2008 545 556
2. S. Lordan, J.J. Mackrill, and N.M. O'Brien Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases J. Nutr. Biochem. 20 2009 321 336
3. G.J. Schroepfer Jr. Oxysterols: modulators of cholesterol metabolism and other processes Physiol. Rev. 80 2000 361 554
4. V. Deckert, L. Persegol, L. Viens, G. Lizard, A. Athias, C. Lallemant, P. Gambert, and L. Lagrost Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation Circulation 95 1997 723 731
5. N. Mougenot, P. Lesnik, J.F. Ramirez-Gil, P. Nataf, U. Diczfalusy, M.J. Chapman, and P. Lechat Effect of the oxidation state of LDL on the modulation of arterial vasomotor response in vitro Atherosclerosis 133 1997 183 192
6. S. Hannedouche, J. Zhang, T. Yi, W. Shen, D. Nguyen, J.P. Pereira, D. Guerini, B.U. Baumgarten, S. Roggo, B. Wen, R. Knochenmuss, S. Noel, F. Gessier, L.M. Kelly, M. Vanek, S. Laurent, I. Preuss, C. Miault, I. Christen, R. Karuna, W. Li, D.I. Koo, T. Suply, C. Schmedt, E.C. Peters, R. Falchetto, A. Katopodis, C. Spanka, M.O. Roy, M. Detheux, Y.A. Chen, P.G. Schultz, C.Y. Cho, K. Seuwen, J.G. Cyster, and A.W. Sailer Oxysterols direct immune cell migration via EBI2 Nature 475 2011 524 527
7. J.L. Witztum, and D. Steinberg Role of oxidized low density lipoprotein in atherogenesis J. Clin. Invest. 88 1991 1785 1792
8. A.J. Brown, and W. Jessup Oxysterols and atherosclerosis Atherosclerosis 142 1999 1 28
9. D.A. Cox, and M.L. Cohen Effects of oxidized low-density lipoprotein on vascular contraction and relaxation: clinical and pharmacological implications in atherosclerosis Pharmacol. Rev. 48 1996 3 19
10. L. Iuliano, F. Micheletta, S. Natoli, S. Ginanni Corradini, M. Iappelli, W. Elisei, L. Giovannelli, F. Violi, and U. Diczfalusy Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status Anal. Biochem. 312 2003 217 223
11. S. Nachtergaele, L.K. Mydock, K. Krishnan, J. Rammohan, P.H. Schlesinger, D.F. Covey, and R. Rohatgi Oxysterols are allosteric activators of the oncoprotein Smoothened Nat. Chem. Biol. 8 2012 211 220
12. J.J. Mackrill Oxysterols and calcium signal transduction Chem. Phys. Lipids 164 2011 488 495
13. M.J. Berridge, M.D. Bootman, and H.L. Roderick Calcium signalling: dynamics, homeostasis and remodelling Nat. Rev. Mol. Cell. Biol. 4 2003 517 529
14. H. Massaeli, J.A. Austria, and G.N. Pierce Chronic exposure of smooth muscle cells to minimally oxidized LDL results in depressed inositol 1,4,5-trisphosphate receptor density and Ca(2+) transients Circ. Res. 85 1999 515 523
15. M.P. Ares, M.I. Porn-Ares, S. Moses, J. Thyberg, L. Juntti-Berggren, P. Berggren, A. Hultgardh-Nilsson, B. Kallin, and J. Nilsson 7beta- hydroxycholesterol induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells Atherosclerosis 153 2000 23 35
16. M.P. Ares, M.I. Porn-Ares, J. Thyberg, L. Juntti-Berggren, P.O. Berggren, U. Diczfalusy, B. Kallin, I. Bjorkhem, S. Orrenius, and J. Nilsson Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells J. Lipid Res. 38 1997 2049 2061
17. H. Massaeli, J.A. Austria, and G.N. Pierce Lesions in ryanodine channels in smooth muscle cells exposed to oxidized low density lipoprotein Arterioscler Thromb. Vasc. Biol. 20 2000 328 334
18. N. Auge, G. Fitoussi, J.L. Bascands, M.T. Pieraggi, D. Junquero, P. Valet, J.P. Girolami, R. Salvayre, and A. Negre-Salvayre Mildly oxidized LDL evokes a sustained Ca(2+)-dependent retraction of vascular smooth muscle cells Circ. Res. 79 1996 871 880
19. H. Kolsch, D. Lutjohann, A. Tulke, I. Bjorkhem, and M.L. Rao The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells Brain Res. 818 1999 171 175
20. O. Thastrup, P.J. Cullen, B.K. Drobak, M.R. Hanley, and A.P. Dawson Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase Proc. Natl. Acad. Sci. U S A 87 1990 2466 2470
21. S. Lordan, N.M. O'Brien, and J.J. Mackrill The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta- epoxide J. Biochem. Mol. Toxicol. 23 2009 324 332
22. Q. Zhou, E. Wasowicz, B. Handler, L. Fleischer, and F.A. Kummerow An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells Atherosclerosis 149 2000 191 197
23. Y.M. Searls, R. Loganathan, I.V. Smirnova, and L. Stehno-Bittel Intracellular Ca2+ regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia Cardiovasc. Diabetol. 9 2010 8
24. D.L. Bennett, T.R. Cheek, M.J. Berridge, H. De Smedt, J.B. Parys, L. Missiaen, and M.D. Bootman Expression and function of ryanodine receptors in nonexcitable cells J. Biol. Chem. 271 1996 6356 6362
25. H. Sipma, L. Deelman, H.D. Smedt, L. Missiaen, J.B. Parys, S. Vanlingen, R.H. Henning, and R. Casteels Agonist-induced down-regulation of type 1 and type 3 inositol 1,4,5-trisphosphate receptors in A7r5 and DDT1 MF-2 smooth muscle cells Cell Calcium 23 1998 11 21
26. W.G. Pierce, C. Zanette, N.M. Caplice, and J.J. Mackrill Calcium signalling in adult endothelial outgrowth cells Biochem. Biophys. Res. Commun. 417 2012 358 363
27. M. Thibonnier, A.L. Bayer, M.S. Simonson, and M. Kester Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells Endocrinology 129 1991 2845 2856
28. T.J. Shuttleworth STIM and Orai proteins and the non-capacitative ARC channels Front. Biosci. 17 2012 847 860
29. B. Kalthof, M. Bechem, L. Pott, and M. Schramm Monitoring of Ca(2+)-transients in electrically stimulated A7r5 vascular smooth muscle cells fills the experimental gap between KCL-induced depolarization and patch-clamp studies J. Pharmacol. Toxicol. Methods 30 1993 143 147
30. F. Zorzato, E. Scutari, V. Tegazzin, E. Clementi, and S. Treves Chlorocresol: an activator of ryanodine receptor-mediated Ca2+ release Mol. Pharmacol. 44 1993 1192 1201
31. R.J. Wojcikiewicz, M.M. Pearce, D.A. Sliter, and Y. Wang When worlds collide: IP(3) receptors and the ERAD pathway Cell Calcium 46 2009 147 153
32. L. Meng, R. Mohan, B.H. Kwok, M. Elofsson, N. Sin, and C.M. Crews Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity Proc. Natl. Acad. Sci. U S A 96 1999 10403 10408
33. P. Vangheluwe, L. Raeymaekers, L. Dode, and F. Wuytack Modulating sarco(endo)plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: cell biological implications Cell Calcium 38 2005 291 302
34. J.J. Mackrill Protein-protein interactions in intracellular Ca2+-release channel function Biochem. J. 337 Pt. 3 1999 345 361
35. R.J. Wojcikiewicz, T. Furuichi, S. Nakade, K. Mikoshiba, and S.R. Nahorski Muscarinic receptor activation down-regulates the type I inositol 1,4,5-trisphosphate receptor by accelerating its degradation J. Biol. Chem. 269 1994 7963 7969
36. J. Liu, C. Netherland, T. Pickle, M.S. Sinensky, and D.P. Thewke Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol Arch. Biochem. Biophys. 487 2009 54 58