Mildly oxidized LDL evokes a sustained Ca2+-dependent retraction of vascular smooth muscle cells

Circulation Research

Volumn 79, Issue 4, 1996, Pages 871-880

  Augé, Nathalie ^a   Fitoussi, Guylène ^a   Bascands, Jean Loup ^a   Pieraggi, Marie Thérèse ^a   Junquero, Didier ^b   Valet, Philippe ^a   Girolami, Jean Pierre ^a   Salvayre, Robert ^a   Nègre Salvayre, Anne ^a,c  

^a INSERM   (France)

^b INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^c CHU RANGUEIL   (France)

Author keywords

atherosclerosis; calcium; oxidized LDL; smooth muscle cells; vascular retraction

Indexed keywords

CALCIUM; LOW DENSITY LIPOPROTEIN;

ANIMAL TISSUE; ARTERY SPASM; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CALCIUM TRANSPORT; CATTLE; LIPID OXIDATION; NONHUMAN; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

EID: 0029797464     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.79.4.871     Document Type: Article

References (52)

1. Goldstein JL, Brown MS. The LDL pathway and its relation to atherosclerosis. Annu Rev Biochem. 1977;46:897-930.
2. Ross R. The pathogenesis of atherosclerosis: an update, N Engl J Med. 1986;314:488-500.
3. Haberland ME, Fong D, Cheng L. Malondialdehyde altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits. Science. 1988;241:215-218.
4. Palinski W, Rosenfeld ME, Ylä-Herttuala S, Gurtner G, Socher SS, Butler S, Parthasarathy S, Carew TE, Steinberg D. Low density lipoprotein undergoes oxidative modifications in vivo. Proc Natl Acad Sci U S A. 1989;86:1372-1376.
5. Steinbrecher UP, Zhang H, Lougheed M. Role of oxidatively modified LDL in atherosclerosis. Free Radic Med Biol. 1990;9:155-168.
6. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modifications of LDL that increase its atherogenicity. N Engl J Med. 1989;320:915-924.
7. Esterbauer H, Dieber-Rotheneder M, Waeg G, Striegl G, Jürgens G. Biochemical, structural and functional properties of oxidized LDL. Chem Res Toxicol. 1990;3:77-92.
8. Ross R. The pathogenesis of atherosclerosis. Nature. 1993;362:801-809.
9. Stary HC. The sequence of cell and matrix changes in atherosclerotic lesions of coronary arteries in the first forty years of life. Ear Heart J. 1990;11(suppl E):3-19.
10. Heistad DD, Armstrong ML, Marcus ML, Piegors DJ, Mark AL. Augmented responses to vasoconstrictor stimuli in hypercholesterolemic and atherosclerotic monkeys. Circ Res. 1984;54:711-718.
11. Galle J, Bassenge R, Busse R. Oxidized LDL potentiate vasoconstrictions to various agonists by direct interaction with vascular smooth muscle. Circ Res. 1990;66:1287-1293.
12. Kugiyama K, Kerns SA, Morrisset JD, Roberts R, Henry PD. Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified LDL. Nature. 1990;344:160-162.
13. Lambert CR, Pepine CJ. Coronary artery spasm and acute myocardial infarction. Cardiovasc Clin. 1989;20:131-140.
14. Maseri A, Davies G, Hackett D, Kaski, JC. Coronary artery spasm and vasoconstriction: the case for a distinction. Circulation. 1990;81:1983-1991.
15. Nègre-Salvayre A, Fitoussi G, Réaud V, Pieraggi MT, Thiers JC, Salvayre R. A delayed and sustained rise of cytosolic calcium is elicited by oxidized LDL in cultured endothelial cells. FEBS Lett. 1992;299:60-65.
16. Nègre-Salvayre A, Salvayre R. UV-treated lipoproteins as a model system for the study of biological effects of lipid peroxides on cultured cells, 4: calcium is involved in the toxicity of UV-treated LDL on lymphoid cell lines. Biochim Biophys Acta. 1992;1123:207-215.
17. Folkman J, Moscona A. Role of cell shape in growth control. Nature. 1978;273:345-349.
18. Skalli O, Bloom WS, Ropraz P, Azzarone B, Gabbiani G. Cytoskeletal remodeling of rat aortic smooth muscle cells in vitro: relationships to culture conditions and analogies to in vivo situations. J Submicrosc Cytol 1986;18:481-493.
19. Desmoulière A, Rubbia-Brandt L, Gabbiani, G. Modulation of actin isoform expression in cultured arterial smooth muscle cells by heparin and culture conditions. Arterioscler Thromb. 1991;11:244-253.
20. Campbell JH, Campbell GR. The role of smooth muscle cells in atherosclerosis. Curr Opin Lipidol. 1994;5:323-330.
21. Poumay Y, Ronveaux-Dupal MF. Rapid preparative isolation of concentrated low density lipoproteins and of lipoprotein-deficient serum using vertical gradient ultracentrifugation. J Lipid Res. 1985;26:1476-1480.
22. Escargueil-Blanc I, Salvayre R, Nègre-Salvayre A. Necrosis and apoptosis induced by oxidized LDL occur through two calcium-dependent pathways in lymphoblastoid cells. FASEB J. 1994;8:1075-1080.
23. Yagi K. Lipid peroxides and human diseases. Chem Phys Lipids. 1987;45:337-351.
24. Lowry OH, Rosebrough NJ, Fair AL, Randall RJ. Protein measurement with Folin phenol reagent J Biol Chem. 1951;193:265-275.
25. Nègre-Salvayre A, Salvayre R. Protection by calcium channel blockers (nifedipine, diltiazem and verapamil) against the toxicity of oxidized low density lipoprotein to cultured lymphoid cells. Br J Pharmacol. 1992;107:738-744.
26. Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods. 1986;89:271-277.
27. Grynkiewicz G, Poenie M, Tsien RY. A new generation of calcium indicators with greatly improved fluorescence properties. J Biol Chem. 1985;260:3440-3450.
28. Bascands JL, Pecher C, Bompart G, Rakotoarivony J, Leung Tack J, Girolami JP. Bradykinin-induced in vitro contraction of rat mesangial cells via B2 receptor type. Am J Physiol. 1994;267:F871-878.
29. Thomas AP, Delaville F. The use of fluorescent indicators for measurement of cytosolic free calcium concentration in cell populations and single cell. In: McCormack JG, Cobbold PH, eds. Cellular Calcium, a Practical Approach. New York, NY: IRL Press; 1991:1-54.
30. Negulescu PA, Machen TE. Intracellular ion activities and membrane transport in parietal cells measured with fluorescent dyes. Methods Enzymol. 1990;192:38-81.
31. Wu L, Hinds R, Vincenzini FF. Assay of the Ca pump ATPase activity of intact red blood cells. Biochim Biophys Acta. 1992;1106:56-62.
32. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373-376.
33. Junquero D, Schini VB, Scott-Burden T, Vanhoutte PM. Enhanced production of nitric oxide in aorta from spontaneously hypertensive rats by IL-10. Am J Hypertens. 1993;6:602-610.
34. Sachinidis A, Locher R, Mengden T, Steiner A, Vetter W. Vasoconstriction: a novel activity for low density lipoprotein. Biochem Biophys Res Commun. 1989;163:315-320.
35. Weisser B, Locher R, Mengden T, Vetter W. Oxidation of low density lipoprotein enhances its potential to increase intracellular free calcium concentration in vascular smooth muscle cells. Arterioscler Thromb. 1992;12:231-236.
36. Bochov V, Tkachuk V, Buhler F, Resink T. Phosphoinositide and calcium responses in smooth muscle cells: comparison between li- poproteins, ang II and PDGF. Biochim Biophys Res Commun. 1992;188:1295-1304.
37. 2+-ATPase. Proc Natl Acad Sci U S A. 1990;87:2466-2470.
38. Saito M, Ishikawa T, Matsushima S, Naka M, Hidaka H. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J Biol Chem. 1987;262:7796-7801.
39. Kamm KE, Stull JT. Regulation of smooth muscle contractile elements by second messengers. Annu Rev Physiol. 1989;51:299-313.
40. Mabile L, Fitoussi G, Perriquet B, Schmitt A, Salvayre R, Nègre-Salvayre A. α-Tocopherol and trolox block the early intracellular events (TBARS and calcium rises) elicited by oxidized low density lipoproteins in cultured endothelial cells. Free Radic Biol Med. 1995;19:177-187.
41. Berridge MJ, Irvine RF. Inositol triphosphate, a novel second messenger in cellular signal transduction. Nature. 1990;341:197-205.
42. Boobis AR, Fawthrop DJ, Davies DS. Mechanism of cell death. Trends Pharmacol Sci. 1989;10:275-280.
43. Nègre-Salvayre A, Lopez M, Levade T, Pierraggi MT, Dousset N, Douste-Blazy L, Salvayre R. UV-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells, II: uptake and cytotoxicity of UV-treated LDL on lymphoid cell lines. Biochim Biophys Acta. 1990;1045:224-232.
44. Fries DM, Penha RG, D'Amico EA, Parra Abdalla DS, Monteiro HP. Oxidized LDL stimulates NO release by rabbit aortic endothelial cells. Biochem Biophys Res Commun. 1995;207:231-237.
45. Hathaway DR, March KL, Lash JA, Adam LP, Wilensky RL. Vascular smooth muscle: a review of the molecular basis of contractility. Circulation. 1991;80:219-233.
46. Rasmussen H, Takuwa Y, Park S. Protein kinase C in the regulation of smooth muscle contraction. FASEB J. 1987;1:177-185.
47. Schmitt A, Nègre-Salvayre A, Delchambre J, Salvayre R. α-Tocopherol and rutin prevent the glutathione and ATP depletion induced by oxidized LDL in cultured endothelial cells. Br J Pharmacol. 1995;116:1985-1990.
48. Strickberger SA, Russek LN, Phair RD. Evidence for increased aortic plasma membrane calcium transport caused by experimental atherosclerosis in rabbits. Circ Res. 1988;62:75-80.
49. Fitoussi G, Nègre-Salvayre A, Pieraggi MT, Salvayre R. New pathogenetic hypothesis for Wolman disease: possible role of oxidized LDL in adrenal necrosis and calcification. Biochem J. 1994;301:267-273.
50. Plane F, Bruckdorfer KR, Kerr P, Steuer A, Jacobs M. Oxidative modification of LDL and the inhibition of relaxations mediated by endothelium-derived NO in rabbit aorta. Br J Pharmacol. 1992;105:216-222.
51. Murohara T, Kugiyama K, Ohgushi M, Sugiyama S, Ohta Y, Yasue H. LPC in oxidized LDL elicit vasocontraction and inhibits endothelium-dependent relaxation. Am J Physiol. 1994;267:H2441-H2449.
52. 2A-adrenoceptors. Eur J Pharmacol. 1989;167:95-104.