Adenosine kinase-deficient mutant of Saccharomyces cerevisiae accumulates S-adenosylmethionine because of an enhanced methionine biosynthesis pathway

Applied Microbiology and Biotechnology

Volumn 97, Issue 3, 2013, Pages 1183-1190

  Kanai, Muneyoshi ^a   Masuda, Mitsunori ^a   Takaoka, Yasumichi ^a   Ikeda, Hiroko ^a   Masaki, Kazuo ^a   Fujii, Tsutomu ^a   Iefuji, Haruyuki ^a  

^a NATIONAL RESEARCH INSTITUTE OF BREWING   (Japan)

Author keywords

Adenosine kinase; Methionine biosynthesis pathway; S Adenosylmethionine; Saccharomyces cerevisiae

Indexed keywords

ADENOSINE KINASE; BUDDING YEASTS; DNA MICROARRAY ANALYSIS; DRY CELLS; GLUTATHIONES; HOMOCYSTEINES; INORGANIC PHOSPHATES; METHIONINE BIOSYNTHESIS; MOLECULAR BASIS; PARENTAL STRAINS; POLYPHOSPHORIC ACIDS; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TETRAHYDROFOLATES; YEAST EXTRACTS; YEAST STRAIN;

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; ENZYMES;

YEAST;

5 METHYLTETRAHYDROFOLIC ACID; ADENOSINE; ADENOSINE KINASE; GLUTATHIONE; HOMOCYSTEINE; METHIONINE; PHOSPHATE; POLYPHOSPHATE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TETRAHYDROFOLIC ACID;

BIOACCUMULATION; DNA; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; PEPTIDE; YEAST;

AMINO ACID SYNTHESIS; ARTICLE; DELETION MUTANT; DNA MICROARRAY; FUNGAL STRAIN; FUNGUS MUTANT; GENE DELETION; GENE LIBRARY; GENE OVEREXPRESSION; HEXOSE TRANSPORT; METABOLITE; NONHUMAN; PHOSPHATE METABOLISM; SACCHAROMYCES CEREVISIAE;

ADENOSINE KINASE; BIOSYNTHETIC PATHWAYS; CROSSES, GENETIC; CULTURE MEDIA; GENE EXPRESSION PROFILING; METABOLOME; METHIONINE; MICROARRAY ANALYSIS; S-ADENOSYLMETHIONINE; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 84874111313     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4261-3     Document Type: Article

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