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Volumn 132, Issue 9, 2013, Pages 2020-2031

Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma

Author keywords

adenocarcinoma; allelic imbalance; copy number alteration; gene amplification; large cell carcinoma; LOH; lung cancer; NSCLC; small cell lung cancer; squamous cell carcinoma

Indexed keywords

DNA;

EID: 84874107467     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27879     Document Type: Article
Times cited : (32)

References (50)
  • 2
    • 36248980204 scopus 로고    scopus 로고
    • Characterizing the cancer genome in lung adenocarcinoma
    • Weir BA, Woo MS, Getz G, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature 2007; 450: 893-8.
    • (2007) Nature , vol.450 , pp. 893-898
    • Weir, B.A.1    Woo, M.S.2    Getz, G.3
  • 3
    • 78650451788 scopus 로고    scopus 로고
    • Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
    • Weiss J, Sos ML, Seidel D, et al. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2010; 2: 62ra93.
    • (2010) Sci Transl Med , vol.2
    • Weiss, J.1    Sos, M.L.2    Seidel, D.3
  • 4
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    • Bhattacharjee A, Richards WG, Staunton J, et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci USA 2001; 98: 13790-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13790-13795
    • Bhattacharjee, A.1    Richards, W.G.2    Staunton, J.3
  • 5
    • 21344437734 scopus 로고    scopus 로고
    • Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis
    • Zhao X, Weir BA, LaFramboise T, et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res 2005; 65: 5561-70.
    • (2005) Cancer Res , vol.65 , pp. 5561-5570
    • Zhao, X.1    Weir, B.A.2    Laframboise, T.3
  • 6
  • 7
    • 79957905683 scopus 로고    scopus 로고
    • Genomic profiles specific to patient ethnicity in lung adenocarcinoma
    • Broet P, Dalmasso C, Tan EH, et al. Genomic profiles specific to patient ethnicity in lung adenocarcinoma. Clin Cancer Res 2011; 17: 3542-50.
    • (2011) Clin Cancer Res , vol.17 , pp. 3542-3550
    • Broet, P.1    Dalmasso, C.2    Tan, E.H.3
  • 8
    • 77955634444 scopus 로고    scopus 로고
    • Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors
    • Voortman J, Lee JH, Killian JK, et al. Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors. Proc Natl Acad Sci USA 2010; 107: 13040-5.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13040-13045
    • Voortman, J.1    Lee, J.H.2    Killian, J.K.3
  • 9
    • 78650092715 scopus 로고    scopus 로고
    • Genomic aberrations in lung adenocarcinoma in never smokers
    • Job B, Bernheim A, Beau-Faller M, et al. Genomic aberrations in lung adenocarcinoma in never smokers. PLoS ONE 2010; 5: e15145.
    • (2010) PLoS ONE , vol.5
    • Job, B.1    Bernheim, A.2    Beau-Faller, M.3
  • 10
    • 80053648465 scopus 로고    scopus 로고
    • Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer
    • Huang YT, Lin X, Liu Y, et al. Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer. Proc Natl Acad Sci USA 2011; 108: 16345-50.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 16345-16350
    • Huang, Y.T.1    Lin, X.2    Liu, Y.3
  • 11
    • 70749140937 scopus 로고    scopus 로고
    • Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation
    • Jaiswal BS, Janakiraman V, Kljavin NM, et al. Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Cancer Cell 2009; 16: 463-74.
    • (2009) Cancer Cell , vol.16 , pp. 463-474
    • Jaiswal, B.S.1    Janakiraman, V.2    Kljavin, N.M.3
  • 12
    • 77953665612 scopus 로고    scopus 로고
    • An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models
    • Lu X, Zhang K, Van Sant C, et al. An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models. BMC Med Genomics 2010; 3: 23.
    • (2010) BMC Med Genomics , vol.3 , pp. 23
    • Lu, X.1    Zhang, K.2    Van Sant, C.3
  • 13
    • 70350641014 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
    • Bass AJ, Watanabe H, Mermel CH, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 2009; 41: 1238-42.
    • (2009) Nat Genet , vol.41 , pp. 1238-1242
    • Bass, A.J.1    Watanabe, H.2    Mermel, C.H.3
  • 14
    • 77249119762 scopus 로고    scopus 로고
    • The landscape of somatic copy-number alteration across human cancers
    • Beroukhim R, Mermel CH, Porter D, et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010; 463: 899-905.
    • (2010) Nature , vol.463 , pp. 899-905
    • Beroukhim, R.1    Mermel, C.H.2    Porter, D.3
  • 15
    • 67651006061 scopus 로고    scopus 로고
    • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
    • Sos ML, Michel K, Zander T, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009; 119: 1727-40.
    • (2009) J Clin Invest , vol.119 , pp. 1727-1740
    • Sos, M.L.1    Michel, K.2    Zander, T.3
  • 16
    • 73549108711 scopus 로고    scopus 로고
    • Amplification of chromosomal segment 4q12 in non-small cell lung cancer
    • Ramos AH, Dutt A, Mermel C, et al. Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biol Ther 2009; 8: 2042-50.
    • (2009) Cancer Biol Ther , vol.8 , pp. 2042-2050
    • Ramos, A.H.1    Dutt, A.2    Mermel, C.3
  • 17
    • 80054924102 scopus 로고    scopus 로고
    • Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer
    • Micke P, Edlund K, Holmberg L, et al. Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer. J Thorac Oncol 2011; 6: 1833-40.
    • (2011) J Thorac Oncol , vol.6 , pp. 1833-1840
    • Micke, P.1    Edlund, K.2    Holmberg, L.3
  • 18
    • 79960974076 scopus 로고    scopus 로고
    • Impact on disease development, genomic location and biological function of copy number alterations in non-small cell lung cancer
    • Huang YT, Lin X, Chirieac LR, et al. Impact on disease development, genomic location and biological function of copy number alterations in non-small cell lung cancer. PLoS ONE 2011; 6: e22961.
    • (2011) PLoS ONE , vol.6
    • Huang, Y.T.1    Lin, X.2    Chirieac, L.R.3
  • 20
    • 77958069025 scopus 로고    scopus 로고
    • Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women
    • Lu TP, Tsai MH, Lee JM, et al. Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women. Cancer Epidemiol Biomarkers Prev 2010; 19: 2590-7.
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 2590-2597
    • Lu, T.P.1    Tsai, M.H.2    Lee, J.M.3
  • 22
    • 68349139723 scopus 로고    scopus 로고
    • An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors
    • Chitale D, Gong Y, Taylor BS, et al. An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. Oncogene 2009; 28: 2773-83.
    • (2009) Oncogene , vol.28 , pp. 2773-2783
    • Chitale, D.1    Gong, Y.2    Taylor, B.S.3
  • 23
    • 77955660663 scopus 로고    scopus 로고
    • Diverse somatic mutation patterns and pathway alterations in human cancers
    • Kan Z, Jaiswal BS, Stinson J, et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 2010; 466: 869-73.
    • (2010) Nature , vol.466 , pp. 869-873
    • Kan, Z.1    Jaiswal, B.S.2    Stinson, J.3
  • 25
    • 33745791118 scopus 로고    scopus 로고
    • Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer
    • Zhou BB, Peyton M, He B, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell 2006; 10: 39-50.
    • (2006) Cancer Cell , vol.10 , pp. 39-50
    • Zhou, B.B.1    Peyton, M.2    He, B.3
  • 26
    • 29144464381 scopus 로고    scopus 로고
    • ArrayExpress. www.ebi.ac.uk/arrayexpress.
    • ArrayExpress
  • 27
    • 69949167276 scopus 로고    scopus 로고
    • A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6
    • Bengtsson H, Wirapati P, Speed TP,. A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6. Bioinformatics 2009; 25: 2149-56.
    • (2009) Bioinformatics , vol.25 , pp. 2149-2156
    • Bengtsson, H.1    Wirapati, P.2    Speed, T.P.3
  • 28
    • 77955047029 scopus 로고    scopus 로고
    • ACNE: A summarization method to estimate allele-specific copy numbers for Affymetrix SNP arrays
    • Ortiz-Estevez M, Bengtsson H, Rubio A,. ACNE: a summarization method to estimate allele-specific copy numbers for Affymetrix SNP arrays. Bioinformatics 2010; 26: 1827-33.
    • (2010) Bioinformatics , vol.26 , pp. 1827-1833
    • Ortiz-Estevez, M.1    Bengtsson, H.2    Rubio, A.3
  • 29
    • 83355161415 scopus 로고    scopus 로고
    • Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
    • Staaf J, Jonsson G, Ringner M, et al. Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer. Breast Cancer Res 2011; 13: R129.
    • (2011) Breast Cancer Res , vol.13
    • Staaf, J.1    Jonsson, G.2    Ringner, M.3
  • 30
    • 12344259648 scopus 로고    scopus 로고
    • Analysis of array CGH data: From signal ratio to gain and loss of DNA regions
    • Hupe P, Stransky N, Thiery JP, et al. Analysis of array CGH data: from signal ratio to gain and loss of DNA regions. Bioinformatics 2004; 20: 3413-22.
    • (2004) Bioinformatics , vol.20 , pp. 3413-3422
    • Hupe, P.1    Stransky, N.2    Thiery, J.P.3
  • 31
    • 77955603605 scopus 로고    scopus 로고
    • Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
    • Russnes HG, Vollan HK, Lingjaerde OC, et al. Genomic architecture characterizes tumor progression paths and fate in breast cancer patients. Sci Transl Med 2010; 2: 38ra47.
    • (2010) Sci Transl Med , vol.2
    • Russnes, H.G.1    Vollan, H.K.2    Lingjaerde, O.C.3
  • 33
    • 45349086985 scopus 로고    scopus 로고
    • Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia-A comparative study of four differently designed, high resolution microarray platforms
    • Gunnarsson R, Staaf J, Jansson M, et al. Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia-A comparative study of four differently designed, high resolution microarray platforms. Genes Chromosomes Cancer 2008; 47: 697-711.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 697-711
    • Gunnarsson, R.1    Staaf, J.2    Jansson, M.3
  • 34
    • 53349171050 scopus 로고    scopus 로고
    • Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays
    • Staaf J, Lindgren D, Vallon-Christersson J, et al. Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays. Genome Biol 2008; 9: R136.
    • (2008) Genome Biol , vol.9
    • Staaf, J.1    Lindgren, D.2    Vallon-Christersson, J.3
  • 35
    • 79955166265 scopus 로고    scopus 로고
    • GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
    • Mermel CH, Schumacher SE, Hill B, et al. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol 2011; 12: R41.
    • (2011) Genome Biol , vol.12
    • Mermel, C.H.1    Schumacher, S.E.2    Hill, B.3
  • 36
    • 76249097734 scopus 로고    scopus 로고
    • Genome Alteration Print (GAP): A tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays
    • Popova T, Manie E, Stoppa-Lyonnet D, et al. Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays. Genome Biol 2009; 10: R128.
    • (2009) Genome Biol , vol.10
    • Popova, T.1    Manie, E.2    Stoppa-Lyonnet, D.3
  • 38
    • 80053389114 scopus 로고    scopus 로고
    • TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer
    • Starczynowski DT, Lockwood WW, Delehouzee S, et al. TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. J Clin Invest 2011; 121: 4095-105.
    • (2011) J Clin Invest , vol.121 , pp. 4095-4105
    • Starczynowski, D.T.1    Lockwood, W.W.2    Delehouzee, S.3
  • 39
    • 34247479418 scopus 로고    scopus 로고
    • High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization
    • Jonsson G, Staaf J, Olsson E, et al. High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization. Genes Chromosomes Cancer 2007; 46: 543-58.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 543-558
    • Jonsson, G.1    Staaf, J.2    Olsson, E.3
  • 41
    • 48649093407 scopus 로고    scopus 로고
    • DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
    • Lockwood WW, Chari R, Coe BP, et al. DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers. Oncogene 2008; 27: 4615-24.
    • (2008) Oncogene , vol.27 , pp. 4615-4624
    • Lockwood, W.W.1    Chari, R.2    Coe, B.P.3
  • 42
    • 77955034636 scopus 로고    scopus 로고
    • Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma
    • Lockwood WW, Chari R, Coe BP, et al. Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. PLoS Med 2010; 7: e1000315.
    • (2010) PLoS Med , vol.7
    • Lockwood, W.W.1    Chari, R.2    Coe, B.P.3
  • 43
    • 77249123407 scopus 로고    scopus 로고
    • Signatures of mutation and selection in the cancer genome
    • Bignell GR, Greenman CD, Davies H, et al. Signatures of mutation and selection in the cancer genome. Nature 2010; 463: 893-8.
    • (2010) Nature , vol.463 , pp. 893-898
    • Bignell, G.R.1    Greenman, C.D.2    Davies, H.3
  • 44
    • 0037037789 scopus 로고    scopus 로고
    • Chromosomal imbalances in human lung cancer
    • Balsara BR, Testa JR,. Chromosomal imbalances in human lung cancer. Oncogene 2002; 21: 6877-83.
    • (2002) Oncogene , vol.21 , pp. 6877-6883
    • Balsara, B.R.1    Testa, J.R.2
  • 45
    • 22144433675 scopus 로고    scopus 로고
    • High-resolution genomic profiles of human lung cancer
    • Tonon G, Wong KK, Maulik G, et al. High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci USA 2005; 102: 9625-30.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9625-9630
    • Tonon, G.1    Wong, K.K.2    Maulik, G.3
  • 46
    • 80052815916 scopus 로고    scopus 로고
    • Prognostic value of chromosomal imbalances in squamous cell carcinoma and adenocarcinoma of the lung
    • Danner BC, Hellms T, Jung K, et al. Prognostic value of chromosomal imbalances in squamous cell carcinoma and adenocarcinoma of the lung. Ann Thorac Surg 2011; 92: 1038-43.
    • (2011) Ann Thorac Surg , vol.92 , pp. 1038-1043
    • Danner, B.C.1    Hellms, T.2    Jung, K.3
  • 47
    • 0034995942 scopus 로고    scopus 로고
    • Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas
    • Pei J, Balsara BR, Li W, et al. Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas. Genes Chromosomes Cancer 2001; 31: 282-7.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 282-287
    • Pei, J.1    Balsara, B.R.2    Li, W.3
  • 48
    • 40049087659 scopus 로고    scopus 로고
    • Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
    • Kang JU, Koo SH, Kwon KC, et al. Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet Cytogenet 2008; 182: 1-11.
    • (2008) Cancer Genet Cytogenet , vol.182 , pp. 1-11
    • Kang, J.U.1    Koo, S.H.2    Kwon, K.C.3
  • 50
    • 70349443682 scopus 로고    scopus 로고
    • Lung cancer in never smokers: Molecular profiles and therapeutic implications
    • Rudin CM, Avila-Tang E, Harris CC, et al. Lung cancer in never smokers: molecular profiles and therapeutic implications. Clin Cancer Res 2009; 15: 5646-61.
    • (2009) Clin Cancer Res , vol.15 , pp. 5646-5661
    • Rudin, C.M.1    Avila-Tang, E.2    Harris, C.C.3


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