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Volumn 8, Issue 21, 2009, Pages 2042-2050

Amplification of chromosomal segment 4q12 in non-small cell lung cancer

(23)  Ramos, Alex H a,b,c   Dutt, Amit a,b   Mermel, Craig a,b,c   Perner, Sven d   Cho, Jeonghee a   Lafargue, Christopher J e   Johnson, Laura A a,b   Stiedl, Ann Cathrin d   Tanaka, Kumiko E a,b   Bass, Adam J a,b   Barretina, Jordi a,b   Weir, Barbara A a,b   Beroukhim, Rameen a,b   Thomas, Roman K f,g   Minna, John D h,i   Chirieac, Lucian R c,j   Lindeman, Neal I c,j   Giordano, Thomas k   Beer, David G k   Wagner, Patrick e   more..


Author keywords

4q12; Amplification; Imatinib; KIT; Lung cancer; NSCLC; PDGFRA; Sunitinib

Indexed keywords

IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR; SUNITINIB;

EID: 73549108711     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.21.9764     Document Type: Article
Times cited : (82)

References (45)
  • 2
    • 7944238044 scopus 로고    scopus 로고
    • Somatic alterations in the human cancer genome
    • Weir B, Zhao X, Meyerson M. Somatic alterations in the human cancer genome. Cancer Cell 2004; 6:433-8.
    • (2004) Cancer Cell , vol.6 , pp. 433-438
    • Weir, B.1    Zhao, X.2    Meyerson, M.3
  • 4
    • 48649093407 scopus 로고    scopus 로고
    • DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
    • Lockwood WW, Chari R, Coe BP, Girard L, Macaulay C, Lam S, et al. DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers. Oncogene 2008; 27:4615-24.
    • (2008) Oncogene , vol.27 , pp. 4615-4624
    • Lockwood, W.W.1    Chari, R.2    Coe, B.P.3    Girard, L.4    Macaulay, C.5    Lam, S.6
  • 6
    • 44449178497 scopus 로고    scopus 로고
    • Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer
    • Kwei KA, Kim YH, Girard L, Kao J, Pacyna-Gengelbach M, Salari K, et al. Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene 2008; 27:3635-40.
    • (2008) Oncogene , vol.27 , pp. 3635-3640
    • Kwei, K.A.1    Kim, Y.H.2    Girard, L.3    Kao, J.4    Pacyna-Gengelbach, M.5    Salari, K.6
  • 8
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007; 316:1039-43.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3    Song, Y.4    Hyland, C.5    Park, J.O.6
  • 9
  • 13
    • 0024452546 scopus 로고    scopus 로고
    • Takahashi T, Nau MM, Chiba I, Birrer MJ, Rosenberg RK, Vinocour M, et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 1989; 246:491-4.
    • Takahashi T, Nau MM, Chiba I, Birrer MJ, Rosenberg RK, Vinocour M, et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 1989; 246:491-4.
  • 16
    • 0029007901 scopus 로고
    • Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers
    • Packenham JP, Taylor JA, White CM, Anna CH, Barrett JC, Devereux TR. Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers. Clin Cancer Res 1995; 1:687-90.
    • (1995) Clin Cancer Res , vol.1 , pp. 687-690
    • Packenham, J.P.1    Taylor, J.A.2    White, C.M.3    Anna, C.H.4    Barrett, J.C.5    Devereux, T.R.6
  • 18
    • 33646716077 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors
    • Ji H, Zhao X, Yuza Y, Shimamura T, Li D, Protopopov A, et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci USA 2006; 103:7817-22.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7817-7822
    • Ji, H.1    Zhao, X.2    Yuza, Y.3    Shimamura, T.4    Li, D.5    Protopopov, A.6
  • 20
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007; 131:1190-203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3    Possemato, A.4    Yu, J.5    Haack, H.6
  • 21
    • 65949104526 scopus 로고    scopus 로고
    • Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors
    • McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, et al. Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors. Cancer Res 2009; 69:3937-46.
    • (2009) Cancer Res , vol.69 , pp. 3937-3946
    • McDermott, U.1    Ames, R.Y.2    Iafrate, A.J.3    Maheswaran, S.4    Stubbs, H.5    Greninger, P.6
  • 22
    • 0041971080 scopus 로고    scopus 로고
    • Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors
    • Hirota S, Ohashi A, Nishida T, Isozaki K, Kinoshita K, Shinomura Y, Kitamura Y. Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors. Gastroenterology 2003; 125:660-7.
    • (2003) Gastroenterology , vol.125 , pp. 660-667
    • Hirota, S.1    Ohashi, A.2    Nishida, T.3    Isozaki, K.4    Kinoshita, K.5    Shinomura, Y.6    Kitamura, Y.7
  • 23
    • 0026793260 scopus 로고
    • Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors
    • Fleming TP, Saxena A, Clark WC, Robertson JT, Oldfield EH, Aaronson SA, Ali IU. Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res 1992; 52:4550-3.
    • (1992) Cancer Res , vol.52 , pp. 4550-4553
    • Fleming, T.P.1    Saxena, A.2    Clark, W.C.3    Robertson, J.T.4    Oldfield, E.H.5    Aaronson, S.A.6    Ali, I.U.7
  • 25
    • 85036779334 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinoma
    • in review
    • Bass A, Watanabe H, Yu S, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinoma. Nat Genet in review.
    • Nat Genet
    • Bass, A.1    Watanabe, H.2    Yu, S.3
  • 26
    • 67651006061 scopus 로고    scopus 로고
    • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
    • Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009; 119:1727-40.
    • (2009) J Clin Invest , vol.119 , pp. 1727-1740
    • Sos, M.L.1    Michel, K.2    Zander, T.3    Weiss, J.4    Frommolt, P.5    Peifer, M.6
  • 27
    • 38049100456 scopus 로고    scopus 로고
    • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
    • Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci USA 2007; 104:20007-12.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20007-20012
    • Beroukhim, R.1    Getz, G.2    Nghiemphu, L.3    Barretina, J.4    Hsueh, T.5    Linhart, D.6
  • 30
    • 37249003928 scopus 로고    scopus 로고
    • Oncogene addiction: Setting the stage for molecularly targeted cancer therapy
    • Sharma SV, Settleman J. Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev 2007; 21:3214-31.
    • (2007) Genes Dev , vol.21 , pp. 3214-3231
    • Sharma, S.V.1    Settleman, J.2
  • 33
    • 33645693156 scopus 로고    scopus 로고
    • Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate
    • Wardelmann E, Merkelbach-Bruse S, Pauls K, Thomas N, Schildhaus HU, Heinicke T, et al. Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate. Clin Cancer Res 2006; 12:1743-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 1743-1749
    • Wardelmann, E.1    Merkelbach-Bruse, S.2    Pauls, K.3    Thomas, N.4    Schildhaus, H.U.5    Heinicke, T.6
  • 34
    • 0035960428 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
    • van Oosterom AT, Judson I, Verweij J, Stroobants S, Donato di Paola E, Dimitrijevic S, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001; 358:1421-3.
    • (2001) Lancet , vol.358 , pp. 1421-1423
    • van Oosterom, A.T.1    Judson, I.2    Verweij, J.3    Stroobants, S.4    Donato di Paola, E.5    Dimitrijevic, S.6
  • 36
    • 44849093414 scopus 로고    scopus 로고
    • A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with anti-angiogenic and antitumour activities
    • Christensen JG. A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with anti-angiogenic and antitumour activities. Ann Oncol 2007; 18:3-10.
    • (2007) Ann Oncol , vol.18 , pp. 3-10
    • Christensen, J.G.1
  • 38
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455:1061-8.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 39
    • 26044467362 scopus 로고    scopus 로고
    • Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme
    • Joensuu H, Puputti M, Sihto H, Tynninen O, Nupponen NN. Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme. J Pathol 2005; 207:224-31.
    • (2005) J Pathol , vol.207 , pp. 224-231
    • Joensuu, H.1    Puputti, M.2    Sihto, H.3    Tynninen, O.4    Nupponen, N.N.5
  • 41
    • 39149120621 scopus 로고    scopus 로고
    • Multicenter, phase II trial of sunitinib in previously treated, advanced non-small-cell lung cancer
    • Socinski MA, Novello S, Brahmer JR, Rosell R, Sanchez JM, Belani CP, et al. Multicenter, phase II trial of sunitinib in previously treated, advanced non-small-cell lung cancer. J Clin Oncol 2008; 26:650-6.
    • (2008) J Clin Oncol , vol.26 , pp. 650-656
    • Socinski, M.A.1    Novello, S.2    Brahmer, J.R.3    Rosell, R.4    Sanchez, J.M.5    Belani, C.P.6
  • 42
    • 73549122986 scopus 로고    scopus 로고
    • TTF1 expression in non-small cell lung carcinoma: Association with TTF1 gene amplification and improved survival
    • Perner S, Wagner P, Soltermann A, Lafargue C, Tischler V, Weir B, et al. TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival. J Pathol 2008.
    • (2008) J Pathol
    • Perner, S.1    Wagner, P.2    Soltermann, A.3    Lafargue, C.4    Tischler, V.5    Weir, B.6
  • 44
    • 33646033137 scopus 로고    scopus 로고
    • A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
    • Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 2006; 124:1283-98.
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3    Kim, S.Y.4    Kloepfer, A.M.5    Hinkle, G.6
  • 45
    • 17844399776 scopus 로고    scopus 로고
    • Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme
    • Giannini C, Sarkaria JN, Saito A, Uhm JH, Galanis E, Carlson BL, et al. Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme. Neuro Oncol 2005; 7:164-76.
    • (2005) Neuro Oncol , vol.7 , pp. 164-176
    • Giannini, C.1    Sarkaria, J.N.2    Saito, A.3    Uhm, J.H.4    Galanis, E.5    Carlson, B.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.