DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers

Oncogene

Volumn 27, Issue 33, 2008, Pages 4615-4624

  Lockwood, W W ^a   Chari, R ^a   Coe, B P ^a   Girard, L ^b   MacAulay, C ^a   Lam, S ^a   Gazdar, A F ^b   Minna, J D ^b   Lam, W L ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Array CGH; EGFR signaling; Gene amplification; Gene expression; Integrative analysis; Lung cancer

Indexed keywords

AKT1 PROTEIN; CYCLIN DEPENDENT KINASE 5; EPIDERMAL GROWTH FACTOR RECEPTOR; SHC1 PROTEIN;

AMPLICON; APOPTOSIS; ARTICLE; BONE CANCER; BREAST CANCER; CANCER CELL CULTURE; CARCINOGENESIS; CELL LINEAGE; CELL PROLIFERATION; CHROMOSOME TRANSLOCATION; COLON CANCER; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENOME; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; LIVER CANCER; LUNG CANCER; LUNG NON SMALL CELL CANCER; MALE; NEOPLASM; ONCOGENE; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION; SKIN CANCER; TUMOR GROWTH; UTERINE CERVIX CANCER;

ANIMALS; CELL LINE, TUMOR; DNA, NEOPLASM; GENE AMPLIFICATION; GENE DOSAGE; GENOME, HUMAN; HUMANS; LUNG NEOPLASMS; ONCOGENE PROTEINS; ONCOGENES; SIGNAL TRANSDUCTION; TRANSLOCATION, GENETIC;

EID: 48649093407     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.98     Document Type: Article

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