The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms

ACS Chemical Neuroscience

Volumn 4, Issue 2, 2013, Pages 310-320

  Coskuner, Orkid ^a   Wise Scira, Olivia ^a   Perry, George ^a   Kitahara, Taizo ^a  

^a UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Alzheimer's disease; amyloid ; missense mutation; molecular dynamics simulations

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; MUTANT PROTEIN; NEW DRUG; OLIGOMER;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; DEMENTIA; HUMAN; MISSENSE MUTATION; MOLECULAR INTERACTION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STRUCTURE; THERMODYNAMICS; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; HUMANS; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84874091627     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn300149j     Document Type: Article

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