Activation of Ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 20769-20773

  Boldogh, Istvan ^a,b   Hajas, Gyorgy ^a   Aguilera Aguirre, Leopoldo ^a   Hegde, Muralidhar L ^a   Radak, Zsolt ^a,c   Bacsi, Attila ^a,d   Sur, Sanjiv ^a,b   Hazra, Tapas K ^a,b   Mitra, Sankar ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

8-OXO-7 ,8-DIHYDROGUANINE; 8-OXOGUANINE; BASE EXCISION REPAIRS; DNA GLYCOSYLASE; EXCHANGE FACTORS; GTPASES; HIGH AFFINITY; MAMMALIAN GENOMES; REACTIVE OXYGEN SPECIES; SIGNALING PATHWAYS;

GENE EXPRESSION; MAMMALS; PHOSPHORYLATION;

POSITIVE IONS;

8 HYDROXYGUANINE; 8 OXOGUANINE DNA GLYCOSYLASE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME BINDING; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; EXCISION REPAIR; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

DNA GLYCOSYLASES; DNA REPAIR; FIBROBLASTS; GENOME, HUMAN; GUANINE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; RAS PROTEINS;

EID: 84862276530     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C112.364620     Document Type: Article

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