TNFα and Fas/FasL pathways are involved in 9-Methoxycamptothecin-induced apoptosis in cancer cells with oxidative stress and G2/M cell cycle arrest

Food and Chemical Toxicology

Volumn 55, Issue , 2013, Pages 396-410

  Wang, Haiyan ^a,b,c,d   Ao, Mingzhang ^a,b,c   Wu, Jiayi ^a,b,c   Yu, Longjiang ^a,b,c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Wuhan Institute of Biotechnology   (China)

^d HUBEI UNIVERSITY OF ARTS AND SCIENCE   (China)

Author keywords

9 Methoxycamptothecin (MCPT); Apoptosis; Fas FasL; G2 M arrest; TNF

Indexed keywords

9 METHOXYCAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; PROTEIN P27; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTIGENS, CD95; APOPTOSIS; BASE SEQUENCE; CAMPTOTHECIN; CELL DIVISION; CELL LINE, TUMOR; DNA PRIMERS; FAS LIGAND PROTEIN; G2 PHASE; HUMANS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84873959107     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.12.059     Document Type: Article

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