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Volumn 8, Issue 2, 2013, Pages

Suppression of LFA-1 Expression by Spermine Is Associated with Enhanced Methylation of ITGAL, the LFA-1 Promoter Area

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLMETHIONINE DECARBOXYLASE; DNA; DNA METHYLTRANSFERASE; EFLORNITHINE; GUANOSINE TRIPHOSPHATASE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; METHYL GROUP; MITOGUAZONE; POLYAMINE; RAP1 PROTEIN; S ADENOSYLMETHIONINE; SPERMIDINE; SPERMINE;

EID: 84873916657     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056056     Document Type: Article
Times cited : (23)

References (45)
  • 1
    • 0024401263 scopus 로고
    • Leukocyte function-associated antigen 1 is an activation molecule for human T cells
    • Wacholtz MC, Patel SS, Lipsky PE, (1989) Leukocyte function-associated antigen 1 is an activation molecule for human T cells. J Exp Med 170: 431-448.
    • (1989) J Exp Med , vol.170 , pp. 431-448
    • Wacholtz, M.C.1    Patel, S.S.2    Lipsky, P.E.3
  • 2
    • 0025806144 scopus 로고
    • Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit
    • Hibbs ML, Xu H, Stacker SA, Springer TA, (1991) Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science 251: 1611-1613.
    • (1991) Science , vol.251 , pp. 1611-1613
    • Hibbs, M.L.1    Xu, H.2    Stacker, S.A.3    Springer, T.A.4
  • 3
    • 0032716259 scopus 로고    scopus 로고
    • Blocking ICAM-1 (CD54) and LFA-1 (CD11a) inhibits experimental allergic conjunctivitis
    • Whitcup SM, Chan CC, Kozhich AT, Magone MT, (1999) Blocking ICAM-1 (CD54) and LFA-1 (CD11a) inhibits experimental allergic conjunctivitis. Clin Immunol 93: 107-113.
    • (1999) Clin Immunol , vol.93 , pp. 107-113
    • Whitcup, S.M.1    Chan, C.C.2    Kozhich, A.T.3    Magone, M.T.4
  • 4
    • 0030443253 scopus 로고    scopus 로고
    • Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1
    • Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, et al. (1996) Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol 157: 4986-4995.
    • (1996) J Immunol , vol.157 , pp. 4986-4995
    • Werther, W.A.1    Gonzalez, T.N.2    O'Connor, S.J.3    McCabe, S.4    Chan, B.5
  • 5
    • 18244370299 scopus 로고    scopus 로고
    • Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
    • Gadek TR, Burdick DJ, McDowell RS, Stanley MS, Marsters JC, et al. (2002) Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule. Science 295: 1086-1089.
    • (2002) Science , vol.295 , pp. 1086-1089
    • Gadek, T.R.1    Burdick, D.J.2    McDowell, R.S.3    Stanley, M.S.4    Marsters, J.C.5
  • 6
    • 0035840830 scopus 로고    scopus 로고
    • The role of leukocyte function-associated antigen-1 in animal models of inflammation
    • Winquist RJ, Desai S, Fogal S, Haynes NA, Nabozny GH, et al. (2001) The role of leukocyte function-associated antigen-1 in animal models of inflammation. Eur J Pharmacol 429: 297-302.
    • (2001) Eur J Pharmacol , vol.429 , pp. 297-302
    • Winquist, R.J.1    Desai, S.2    Fogal, S.3    Haynes, N.A.4    Nabozny, G.H.5
  • 7
    • 0032722001 scopus 로고    scopus 로고
    • Phenotypic and functional characteristics of circulating monocytes of elderly persons
    • Sadeghi HM, Schnelle JF, Thoma JK, Nishanian P, Fahey JL, (1999) Phenotypic and functional characteristics of circulating monocytes of elderly persons. Exp Gerontol 34: 959-970.
    • (1999) Exp Gerontol , vol.34 , pp. 959-970
    • Sadeghi, H.M.1    Schnelle, J.F.2    Thoma, J.K.3    Nishanian, P.4    Fahey, J.L.5
  • 9
    • 0031878352 scopus 로고    scopus 로고
    • Quantitative intracellular cytokine measurement: age-related changes in proinflammatory cytokine production
    • O'Mahony L, Holland J, Jackson J, Feighery C, Hennessy TP, et al. (1998) Quantitative intracellular cytokine measurement: age-related changes in proinflammatory cytokine production. Clin Exp Immunol 113: 213-219.
    • (1998) Clin Exp Immunol , vol.113 , pp. 213-219
    • O'Mahony, L.1    Holland, J.2    Jackson, J.3    Feighery, C.4    Hennessy, T.P.5
  • 10
    • 0029871836 scopus 로고    scopus 로고
    • Cytokine production by T lymphocytes from young and aged mice
    • Engwerda CR, Fox BS, Handwerger BS, (1996) Cytokine production by T lymphocytes from young and aged mice. J Immunol 156: 3621-3630.
    • (1996) J Immunol , vol.156 , pp. 3621-3630
    • Engwerda, C.R.1    Fox, B.S.2    Handwerger, B.S.3
  • 11
    • 0026718001 scopus 로고
    • Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains
    • Powers DC, Morley JE, Flood JF, (1992) Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains. Cell Immunol 141: 444-456.
    • (1992) Cell Immunol , vol.141 , pp. 444-456
    • Powers, D.C.1    Morley, J.E.2    Flood, J.F.3
  • 12
    • 0032512808 scopus 로고    scopus 로고
    • Evaluation of the age-dependent development of lymphocyte surface receptors in children
    • Neubert R, Delgado I, Abraham K, Schuster C, Helge H, (1998) Evaluation of the age-dependent development of lymphocyte surface receptors in children. Life Sci 62: 1099-1110.
    • (1998) Life Sci , vol.62 , pp. 1099-1110
    • Neubert, R.1    Delgado, I.2    Abraham, K.3    Schuster, C.4    Helge, H.5
  • 13
    • 0036098657 scopus 로고    scopus 로고
    • Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter
    • Zhang Z, Deng C, Lu Q, Richardson B, (2002) Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter. Mech Ageing Dev 123: 1257-1268.
    • (2002) Mech Ageing Dev , vol.123 , pp. 1257-1268
    • Zhang, Z.1    Deng, C.2    Lu, Q.3    Richardson, B.4
  • 14
    • 0036328026 scopus 로고    scopus 로고
    • Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer
    • Richardson BC, (2002) Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer. J Nutr 132: 2401S-2405S.
    • (2002) J Nutr , vol.132
    • Richardson, B.C.1
  • 15
    • 0036095885 scopus 로고    scopus 로고
    • Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
    • Lu Q, Kaplan M, Ray D, Ray D, Zacharek S, et al. (2002) Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. Arthritis Rheum 46: 1282-1291.
    • (2002) Arthritis Rheum , vol.46 , pp. 1282-1291
    • Lu, Q.1    Kaplan, M.2    Ray, D.3    Ray, D.4    Zacharek, S.5
  • 17
    • 0024145725 scopus 로고
    • Polyamines, DNA methylation and cell differentiation
    • Heby O, Persson L, Smith SS, (1988) Polyamines, DNA methylation and cell differentiation. Adv Exp Med Biol 250: 291-299.
    • (1988) Adv Exp Med Biol , vol.250 , pp. 291-299
    • Heby, O.1    Persson, L.2    Smith, S.S.3
  • 18
    • 0035354580 scopus 로고    scopus 로고
    • Polyamines: new cues in cellular signal transduction
    • Bachrach U, Wang YC, Tabib A, (2001) Polyamines: new cues in cellular signal transduction. News Physiol Sci 16: 106-109.
    • (2001) News Physiol Sci , vol.16 , pp. 106-109
    • Bachrach, U.1    Wang, Y.C.2    Tabib, A.3
  • 19
    • 21244481237 scopus 로고    scopus 로고
    • Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte
    • Soda K, Kano Y, Nakamura T, Kasono K, Kawakami M, et al. (2005) Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte. J Immunol 175: 237-245.
    • (2005) J Immunol , vol.175 , pp. 237-245
    • Soda, K.1    Kano, Y.2    Nakamura, T.3    Kasono, K.4    Kawakami, M.5
  • 20
    • 0030965838 scopus 로고    scopus 로고
    • Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response
    • Zhang M, Caragine T, Wang H, Cohen PS, Botchkina G, et al. (1997) Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. J Exp Med 185: 1759-1768.
    • (1997) J Exp Med , vol.185 , pp. 1759-1768
    • Zhang, M.1    Caragine, T.2    Wang, H.3    Cohen, P.S.4    Botchkina, G.5
  • 21
    • 84862798731 scopus 로고    scopus 로고
    • Current advances in epigenetic modification and alteration during mammalian ovarian folliculogenesis
    • Pan Z, Zhang J, Li Q, Li Y, Shi F, et al. (2012) Current advances in epigenetic modification and alteration during mammalian ovarian folliculogenesis. Genet Genomics 39: 111-123.
    • (2012) Genet Genomics , vol.39 , pp. 111-123
    • Pan, Z.1    Zhang, J.2    Li, Q.3    Li, Y.4    Shi, F.5
  • 22
    • 78650447193 scopus 로고    scopus 로고
    • Hormonal gene regulation through DNA methylation and demethylation
    • Kouzmenko A, Ohtake F, Fujiki R, Kato S, (2010) Hormonal gene regulation through DNA methylation and demethylation. Epigenomics 2: 765-774.
    • (2010) Epigenomics , vol.2 , pp. 765-774
    • Kouzmenko, A.1    Ohtake, F.2    Fujiki, R.3    Kato, S.4
  • 23
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A, (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 24
    • 4744348332 scopus 로고    scopus 로고
    • Differential DNA methylation reprogramming of various repetitive sequences in mouse preimplantation embryos
    • Kim SH, Kang YK, Koo DB, Kang MJ, Moon SJ, et al. (2004) Differential DNA methylation reprogramming of various repetitive sequences in mouse preimplantation embryos. Biochem Biophys Res Commun 324: 58-63.
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 58-63
    • Kim, S.H.1    Kang, Y.K.2    Koo, D.B.3    Kang, M.J.4    Moon, S.J.5
  • 26
    • 77649342230 scopus 로고    scopus 로고
    • Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes
    • Li Y, Liu Y, Strickland FM, Richardson B, (2010) Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes. Exp Gerontol 45: 312-322.
    • (2010) Exp Gerontol , vol.45 , pp. 312-322
    • Li, Y.1    Liu, Y.2    Strickland, F.M.3    Richardson, B.4
  • 29
    • 0035804216 scopus 로고    scopus 로고
    • Induction of epithelial differentiation and DNA demethylation in hamster malignant oral keratinocyte by ornithine decarboxylase antizyme
    • Tsuji T, Usui S, Aida T, Tachikawa T, Hu GF, et al. (2001) Induction of epithelial differentiation and DNA demethylation in hamster malignant oral keratinocyte by ornithine decarboxylase antizyme. Oncogene 20: 24-33.
    • (2001) Oncogene , vol.20 , pp. 24-33
    • Tsuji, T.1    Usui, S.2    Aida, T.3    Tachikawa, T.4    Hu, G.F.5
  • 30
    • 78149430876 scopus 로고    scopus 로고
    • Molecular coupling of DNA methylation and histone methylation
    • Hashimoto H, Vertino PM, Cheng X, (2010) Molecular coupling of DNA methylation and histone methylation. Epigenomics 2: 657-669.
    • (2010) Epigenomics , vol.2 , pp. 657-669
    • Hashimoto, H.1    Vertino, P.M.2    Cheng, X.3
  • 32
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll MG, Bestor TH, (2005) Eukaryotic cytosine methyltransferases. Ann Rev Biochem 74: 481-514.
    • (2005) Ann Rev Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 33
    • 0031058038 scopus 로고    scopus 로고
    • Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion
    • Frostesjo L, Holm I, Grahn B, Page AW, Bestor TH, et al. (1997) Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion. J Biol Chem 272: 4359-4366.
    • (1997) J Biol Chem , vol.272 , pp. 4359-4366
    • Frostesjo, L.1    Holm, I.2    Grahn, B.3    Page, A.W.4    Bestor, T.H.5
  • 34
    • 79551480472 scopus 로고    scopus 로고
    • Spermine synthase activity affects the content of decarboxylated S-adenosylmethionine
    • Pegg AE, Wang X, Schwartz CE, McCloskey DE, (2011) Spermine synthase activity affects the content of decarboxylated S-adenosylmethionine. Biochem J 433: 139-144.
    • (2011) Biochem J , vol.433 , pp. 139-144
    • Pegg, A.E.1    Wang, X.2    Schwartz, C.E.3    McCloskey, D.E.4
  • 35
    • 77958610739 scopus 로고    scopus 로고
    • Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line
    • Yamamoto D, Shima K, Matsuo K, Nishioka T, Chen CY, et al. (2010) Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line. PLoS One 5: e12554.
    • (2010) PLoS One , vol.5
    • Yamamoto, D.1    Shima, K.2    Matsuo, K.3    Nishioka, T.4    Chen, C.Y.5
  • 36
    • 0019498751 scopus 로고
    • Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells
    • Mamont PS, Joder-Ohlenbusch AM, Nussli M, Grove J, (1981) Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells. Biochem J 196: 411-422.
    • (1981) Biochem J , vol.196 , pp. 411-422
    • Mamont, P.S.1    Joder-Ohlenbusch, A.M.2    Nussli, M.3    Grove, J.4
  • 37
    • 0026464734 scopus 로고
    • Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content
    • Shantz LM, Holm I, Janne OA, Pegg AE, (1992) Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content. Biochem J 288 (Pt 2): 511-518.
    • (1992) Biochem J , vol.288 , Issue.Pt 2 , pp. 511-518
    • Shantz, L.M.1    Holm, I.2    Janne, O.A.3    Pegg, A.E.4
  • 38
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor T, Laudano A, Mattaliano R, Ingram V, (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 203: 971-983.
    • (1988) J Mol Biol , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 39
    • 0024399582 scopus 로고
    • Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio
    • Garcea R, Daino L, Pascale R, Simile MM, Puddu M, et al. (1989) Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio. Carcinogenesis 10: 1183-1192.
    • (1989) Carcinogenesis , vol.10 , pp. 1183-1192
    • Garcea, R.1    Daino, L.2    Pascale, R.3    Simile, M.M.4    Puddu, M.5
  • 40
    • 33847034860 scopus 로고    scopus 로고
    • Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer
    • Pulukuri SM, Estes N, Patel J, Rao JS, (2007) Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer. Cancer Res 67: 930-939.
    • (2007) Cancer Res , vol.67 , pp. 930-939
    • Pulukuri, S.M.1    Estes, N.2    Patel, J.3    Rao, J.S.4
  • 41
    • 0348036122 scopus 로고    scopus 로고
    • T-cell integrins: more than just sticking points
    • Hogg N, Laschinger M, Giles K, McDowall A, (2003) T-cell integrins: more than just sticking points. J Cell Sci 116: 4695-4705.
    • (2003) J Cell Sci , vol.116 , pp. 4695-4705
    • Hogg, N.1    Laschinger, M.2    Giles, K.3    McDowall, A.4
  • 42
    • 34447301486 scopus 로고    scopus 로고
    • Small GTPases and LFA-1 reciprocally modulate adhesion and signaling
    • Mor A, Dustin ML, Philips MR, (2007) Small GTPases and LFA-1 reciprocally modulate adhesion and signaling. Immunol Rev 218: 114-125.
    • (2007) Immunol Rev , vol.218 , pp. 114-125
    • Mor, A.1    Dustin, M.L.2    Philips, M.R.3
  • 43
    • 0036009116 scopus 로고    scopus 로고
    • Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
    • Sebzda E, Bracke M, Tugal T, Hogg N, Cantrell DA, (2002) Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat Immunol 3: 251-258.
    • (2002) Nat Immunol , vol.3 , pp. 251-258
    • Sebzda, E.1    Bracke, M.2    Tugal, T.3    Hogg, N.4    Cantrell, D.A.5
  • 44
    • 0033569769 scopus 로고    scopus 로고
    • Functional interaction between GCN5 and polyamines: a new role for core histone acetylation
    • Pollard KJ, Samuels ML, Crowley KA, Hansen JC, Peterson CL, (1999) Functional interaction between GCN5 and polyamines: a new role for core histone acetylation. EMBO J 18: 5622-5633.
    • (1999) EMBO J , vol.18 , pp. 5622-5633
    • Pollard, K.J.1    Samuels, M.L.2    Crowley, K.A.3    Hansen, J.C.4    Peterson, C.L.5


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