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Volumn 20, Issue 2, 2013, Pages 117-124

Clinical applications of novel ERG immunohistochemistry in prostate cancer diagnosis and management

Author keywords

ERG antibody; prostate cancer; TMPRSS2:ERG gene fusions

Indexed keywords

2 METHYLACYL COENZYME A RACEMASE; CELL MARKER; CYTOKERATIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN P63; TRANSCRIPTION FACTOR ERG;

EID: 84873898811     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e3182862ac5     Document Type: Review
Times cited : (40)

References (56)
  • 1
    • 66349115692 scopus 로고    scopus 로고
    • The discovery of common recurrent transmembrane protease serine 2 (TMPRSS2)- erythroblastosis virus E26 transforming sequence (ETS) gene fusions in prostate cancer: Significance and clinical implications
    • Shah RB, Chinnaiyan AM. The discovery of common recurrent transmembrane protease serine 2 (TMPRSS2)- erythroblastosis virus E26 transforming sequence (ETS) gene fusions in prostate cancer: significance and clinical implications. Adv Anat Pathol. 2009; 16: 145-153.
    • (2009) Adv Anat Pathol , vol.16 , pp. 145-153
    • Shah, R.B.1    Chinnaiyan, A.M.2
  • 2
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005; 310: 644-648.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 3
    • 34247363715 scopus 로고    scopus 로고
    • Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer
    • Mehra R, Tomlins SA, Shen R, et al. Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer. Mod Pathol. 2007; 20: 538-544.
    • (2007) Mod Pathol , vol.20 , pp. 538-544
    • Mehra, R.1    Tomlins, S.A.2    Shen, R.3
  • 4
    • 68049101459 scopus 로고    scopus 로고
    • Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States
    • Mosquera JM, Mehra R, Regan MM, et al. Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States. Clin Cancer Res. 2009; 15: 4706-4711.
    • (2009) Clin Cancer Res , vol.15 , pp. 4706-4711
    • Mosquera, J.M.1    Mehra, R.2    Regan, M.M.3
  • 5
    • 33749029695 scopus 로고    scopus 로고
    • TMPRSS2: ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
    • Perner S, Demichelis F, Beroukhim R, et al. TMPRSS2: ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res. 2006; 66: 8337-8341.
    • (2006) Cancer Res , vol.66 , pp. 8337-8341
    • Perner, S.1    Demichelis, F.2    Beroukhim, R.3
  • 6
    • 54749111457 scopus 로고    scopus 로고
    • A fluorescence in situ hybridization screen for E26 transformation- specific aberrations: Identification of DDX5-ETV4 fusion protein in prostate cancer
    • Han B, Mehra R, Dhanasekaran SM, et al. A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. Cancer Res. 2008; 68: 7629-7637.
    • (2008) Cancer Res , vol.68 , pp. 7629-7637
    • Han, B.1    Mehra, R.2    Dhanasekaran, S.M.3
  • 7
    • 39049170313 scopus 로고    scopus 로고
    • Characterization of TMPRSS2: ETV5 and SLC45A3: ETV5 gene fusions in prostate cancer
    • Helgeson BE, Tomlins SA, Shah N, et al. Characterization of TMPRSS2: ETV5 and SLC45A3: ETV5 gene fusions in prostate cancer. Cancer Res. 2008; 68: 73-80.
    • (2008) Cancer Res , vol.68 , pp. 73-80
    • Helgeson, B.E.1    Tomlins, S.A.2    Shah, N.3
  • 8
    • 77955716677 scopus 로고    scopus 로고
    • ERG oncoprotein expression in prostate cancer: Clonal progression of ERGpositive tumor cells and potential for ERG-based stratification
    • Furusato B, Tan SH, Young D, et al. ERG oncoprotein expression in prostate cancer: clonal progression of ERGpositive tumor cells and potential for ERG-based stratification. Prostate Cancer Prostatic Dis. 2010; 13: 228-237.
    • (2010) Prostate Cancer Prostatic Dis , vol.13 , pp. 228-237
    • Furusato, B.1    Tan, S.H.2    Young, D.3
  • 9
    • 68249083702 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression
    • Han B, Mehra R, Lonigro RJ, et al. Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression. Mod Pathol. 2009; 22: 1083-1093.
    • (2009) Mod Pathol , vol.22 , pp. 1083-1093
    • Han, B.1    Mehra, R.2    Lonigro, R.J.3
  • 10
    • 50349093250 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
    • Mosquera JM, Perner S, Genega EM, et al. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin Cancer Res. 2008; 14: 3380-3385.
    • (2008) Clin Cancer Res , vol.14 , pp. 3380-3385
    • Mosquera, J.M.1    Perner, S.2    Genega, E.M.3
  • 11
    • 34447342868 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
    • Perner S, Mosquera JM, Demichelis F, et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am J Surg Pathol. 2007; 31: 882-888.
    • (2007) Am J Surg Pathol , vol.31 , pp. 882-888
    • Perner, S.1    Mosquera, J.M.2    Demichelis, F.3
  • 12
    • 34548572763 scopus 로고    scopus 로고
    • Heterogeneity of TMPRSS2 gene rearrangements in multifocal prostate adenocarcinoma: Molecular evidence for an independent group of diseases
    • Mehra R, Han B, Tomlins SA, et al. Heterogeneity of TMPRSS2 gene rearrangements in multifocal prostate adenocarcinoma: molecular evidence for an independent group of diseases. Cancer Res. 2007; 67: 7991-7995.
    • (2007) Cancer Res , vol.67 , pp. 7991-7995
    • Mehra, R.1    Han, B.2    Tomlins, S.A.3
  • 13
    • 45549090259 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer
    • Mehra R, Tomlins SA, Yu J, et al. Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer. Cancer Res. 2008; 68: 3584-3590.
    • (2008) Cancer Res , vol.68 , pp. 3584-3590
    • Mehra, R.1    Tomlins, S.A.2    Yu, J.3
  • 14
    • 84858288121 scopus 로고    scopus 로고
    • Clinical potential of the ERG oncoprotein in prostate cancer
    • Rosen P, Sesterhenn IA, Brassell SA, et al. Clinical potential of the ERG oncoprotein in prostate cancer. Nat Rev Urol. 2012; 9: 131-137.
    • (2012) Nat Rev Urol , vol.9 , pp. 131-137
    • Rosen, P.1    Sesterhenn, I.A.2    Brassell, S.A.3
  • 15
    • 77950201422 scopus 로고    scopus 로고
    • ETS gene aberrations in atypical cribriform lesions of the prostate: Implications for the distinction between intraductal carcinoma of the prostate and cribriform high-grade prostatic intraepithelial neoplasia
    • Han B, Suleman K, Wang L, et al. ETS gene aberrations in atypical cribriform lesions of the prostate: implications for the distinction between intraductal carcinoma of the prostate and cribriform high-grade prostatic intraepithelial neoplasia. Am J Surg Pathol. 2010; 34: 478-485.
    • (2010) Am J Surg Pathol , vol.34 , pp. 478-485
    • Han, B.1    Suleman, K.2    Wang, L.3
  • 16
    • 77954997528 scopus 로고    scopus 로고
    • Antibody-based detection of ERG rearrangement-positive prostate cancer
    • Park K, Tomlins SA, Mudaliar KM, et al. Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia. 2010; 12: 590-598.
    • (2010) Neoplasia , vol.12 , pp. 590-598
    • Park, K.1    Tomlins, S.A.2    Mudaliar, K.M.3
  • 17
    • 20444493600 scopus 로고    scopus 로고
    • Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
    • Petrovics G, Liu A, Shaheduzzaman S, et al. Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene. 2005; 24: 3847-3852.
    • (2005) Oncogene , vol.24 , pp. 3847-3852
    • Petrovics, G.1    Liu, A.2    Shaheduzzaman, S.3
  • 18
    • 79959660044 scopus 로고    scopus 로고
    • Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas
    • Chaux A, Albadine R, Toubaji A, et al. Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas. Am J Surg Pathol. 2011; 35: 1014-1020.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1014-1020
    • Chaux, A.1    Albadine, R.2    Toubaji, A.3
  • 19
    • 80855124842 scopus 로고    scopus 로고
    • ERG gene rearrangement status in prostate cancer detected by immunohistochemistry
    • Falzarano SM, Zhou M, Carver P, et al. ERG gene rearrangement status in prostate cancer detected by immunohistochemistry. Virchows Arch. 2011; 459: 441-447.
    • (2011) Virchows Arch , vol.459 , pp. 441-447
    • Falzarano, S.M.1    Zhou, M.2    Carver, P.3
  • 20
    • 79961031183 scopus 로고    scopus 로고
    • Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: Implications for pathological practice
    • van Leenders GJ, Boormans JL, Vissers CJ, et al. Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: implications for pathological practice. Mod Pathol. 2011; 24: 1128-1138.
    • (2011) Mod Pathol , vol.24 , pp. 1128-1138
    • Van Leenders, G.J.1    Boormans, J.L.2    Vissers, C.J.3
  • 21
    • 84862080503 scopus 로고    scopus 로고
    • ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer - A comparative study of two monoclonal antibodies
    • Braun M, Goltz D, Shaikhibrahim Z, et al. ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer - a comparative study of two monoclonal antibodies. Prostate Cancer Prostatic Dis. 2012; 15: 165-169.
    • (2012) Prostate Cancer Prostatic Dis , vol.15 , pp. 165-169
    • Braun, M.1    Goltz, D.2    Shaikhibrahim, Z.3
  • 22
    • 31644443311 scopus 로고    scopus 로고
    • Immunohistochemistry in diagnostic surgical pathology of the prostate
    • Hameed O, Humphrey PA. Immunohistochemistry in diagnostic surgical pathology of the prostate. Semin Diagn Pathol. 2005; 22: 88-104.
    • (2005) Semin Diagn Pathol , vol.22 , pp. 88-104
    • Hameed, O.1    Humphrey, P.A.2
  • 23
    • 22144496489 scopus 로고    scopus 로고
    • Diagnostic utility of immunohistochemistry in morphologically difficult prostate cancer: Review of current literature
    • Varma M, Jasani B. Diagnostic utility of immunohistochemistry in morphologically difficult prostate cancer: review of current literature. Histopathology. 2005; 47: 1-16.
    • (2005) Histopathology , vol.47 , pp. 1-16
    • Varma, M.1    Jasani, B.2
  • 24
    • 37549044281 scopus 로고    scopus 로고
    • Partial atrophy in prostate needle biopsies: A detailed analysis of its morphology, immunophenotype, and cellular kinetics
    • Przybycin CG, Kunju LP, Wu AJ, et al. Partial atrophy in prostate needle biopsies: a detailed analysis of its morphology, immunophenotype, and cellular kinetics. Am J Surg Pathol. 2008; 32: 58-64.
    • (2008) Am J Surg Pathol , vol.32 , pp. 58-64
    • Przybycin, C.G.1    Kunju, L.P.2    Wu, A.J.3
  • 25
    • 4644245223 scopus 로고    scopus 로고
    • Usefulness of basal cell cocktail (34betaE12 +p63) in the diagnosis of atypical prostate glandular proliferations
    • Shah RB, Kunju LP, Shen R, et al. Usefulness of basal cell cocktail (34betaE12 +p63) in the diagnosis of atypical prostate glandular proliferations. Am J Clin Pathol. 2004; 122: 517-523.
    • (2004) Am J Clin Pathol , vol.122 , pp. 517-523
    • Shah, R.B.1    Kunju, L.P.2    Shen, R.3
  • 26
    • 0036723906 scopus 로고    scopus 로고
    • Comparison of the basal cell-specific markers, 34betaE12 and p63, in the diagnosis of prostate cancer
    • Shah RB, Zhou M, LeBlanc M, et al. Comparison of the basal cell-specific markers, 34betaE12 and p63, in the diagnosis of prostate cancer. Am J Surg Pathol. 2002; 26: 1161-1168.
    • (2002) Am J Surg Pathol , vol.26 , pp. 1161-1168
    • Shah, R.B.1    Zhou, M.2    Leblanc, M.3
  • 27
    • 0036724297 scopus 로고    scopus 로고
    • Can basal cells be seen in adenocarcinoma of the prostate?: An immunohistochemical study using high molecular weight cytokeratin (clone 34betaE12) antibody
    • Oliai BR, Kahane H, Epstein JI. Can basal cells be seen in adenocarcinoma of the prostate?: An immunohistochemical study using high molecular weight cytokeratin (clone 34betaE12) antibody. Am J Surg Pathol. 2002; 26: 1151-1160.
    • (2002) Am J Surg Pathol , vol.26 , pp. 1151-1160
    • Oliai, B.R.1    Kahane, H.2    Epstein, J.I.3
  • 28
    • 40849126971 scopus 로고    scopus 로고
    • Aberrant diffuse expression of p63 in adenocarcinoma of the prostate on needle biopsy and radical prostatectomy: Report of 21 cases
    • Osunkoya AO, Hansel DE, Sun X, et al. Aberrant diffuse expression of p63 in adenocarcinoma of the prostate on needle biopsy and radical prostatectomy: report of 21 cases. Am J Surg Pathol. 2008; 32: 461-467.
    • (2008) Am J Surg Pathol , vol.32 , pp. 461-467
    • Osunkoya, A.O.1    Hansel, D.E.2    Sun, X.3
  • 29
    • 28844478175 scopus 로고    scopus 로고
    • Comparison of monoclonal antibody (P504S) and polyclonal antibody to alpha methylacyl-CoA racemase (AMACR) in the work-up of prostate cancer
    • Kunju LP, Chinnaiyan AM, Shah RB. Comparison of monoclonal antibody (P504S) and polyclonal antibody to alpha methylacyl-CoA racemase (AMACR) in the work-up of prostate cancer. Histopathology. 2005; 47: 587-596.
    • (2005) Histopathology , vol.47 , pp. 587-596
    • Kunju, L.P.1    Chinnaiyan, A.M.2    Shah, R.B.3
  • 30
    • 0242332137 scopus 로고    scopus 로고
    • Diagnostic usefulness of monoclonal antibody P504S in the workup of atypical prostatic glandular proliferations
    • Kunju LP, Rubin MA, Chinnaiyan AM, et al. Diagnostic usefulness of monoclonal antibody P504S in the workup of atypical prostatic glandular proliferations. Am J Clin Pathol. 2003; 120: 737-745.
    • (2003) Am J Clin Pathol , vol.120 , pp. 737-745
    • Kunju, L.P.1    Rubin, M.A.2    Chinnaiyan, A.M.3
  • 31
    • 79959684555 scopus 로고    scopus 로고
    • The utility of ERG/ P63 double immunohistochemical staining in the diagnosis of limited cancer in prostate needle biopsies
    • Yaskiv O, Zhang X, Simmerman K, et al. The utility of ERG/ P63 double immunohistochemical staining in the diagnosis of limited cancer in prostate needle biopsies. Am J Surg Pathol. 2011; 35: 1062-1068.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1062-1068
    • Yaskiv, O.1    Zhang, X.2    Simmerman, K.3
  • 32
    • 84865013222 scopus 로고    scopus 로고
    • Antibody-based detection of ERG rearrangements in prostate core biopsies, including diagnostically challenging cases: ERG staining in prostate core biopsies
    • Tomlins SA, Palanisamy N, Siddiqui J, et al. Antibody-based detection of ERG rearrangements in prostate core biopsies, including diagnostically challenging cases: ERG staining in prostate core biopsies. Arch Pathol Lab Med. 2012; 136: 935-946.
    • (2012) Arch Pathol Lab Med , vol.136 , pp. 935-946
    • Tomlins, S.A.1    Palanisamy, N.2    Siddiqui, J.3
  • 33
    • 84876477157 scopus 로고    scopus 로고
    • The diagnostic use of ERG in resolving an "atypical glands suspicious for cancer" diagnosis in prostate biopsies beyond that provided by basal cell and alpha-methylacyl-CoA-racemase markers
    • Nov. 41. [Epub ahead of print]
    • Shah RB, Tadros Y, Brummell B, et al. The diagnostic use of ERG in resolving an "atypical glands suspicious for cancer" diagnosis in prostate biopsies beyond that provided by basal cell and alpha-methylacyl-CoA- racemase markers. Hum Pathol. 2012, Nov. 14. [Epub ahead of print].
    • (2012) Hum Pathol.
    • Shah, R.B.1    Tadros, Y.2    Brummell, B.3
  • 34
    • 84864442088 scopus 로고    scopus 로고
    • ERG rearrangement for predicting subsequent cancer diagnosis in high-grade prostatic intraepithelial neoplasia and lymph node metastasis
    • Gao X, Li LY, Zhou FJ, et al. ERG rearrangement for predicting subsequent cancer diagnosis in high-grade prostatic intraepithelial neoplasia and lymph node metastasis. Clin Cancer Res. 2012; 18: 4163-4172.
    • (2012) Clin Cancer Res , vol.18 , pp. 4163-4172
    • Gao, X.1    Li, L.Y.2    Zhou, F.J.3
  • 35
    • 84876452523 scopus 로고    scopus 로고
    • Expression of ERG protein, a prostate cancer specific marker, in high grade prostatic intraepithelial neoplasia (HGPIN): Lack of utility to stratify cancer risks associated with HGPIN
    • Oct 9. [Epub ahead of print]
    • He H, Osunkoya AO, Carver P, et al. Expression of ERG protein, a prostate cancer specific marker, in high grade prostatic intraepithelial neoplasia (HGPIN): lack of utility to stratify cancer risks associated with HGPIN. BJU Int. 2012. Oct 9. [Epub ahead of print].
    • (2012) BJU Int.
    • He, H.1    Osunkoya, A.O.2    Carver, P.3
  • 36
    • 79953169828 scopus 로고    scopus 로고
    • The diagnostic utility of novel immunohistochemical marker ERG in the workup of prostate biopsies with "atypical glands suspicious for cancer"
    • He H, Magi-Galluzzi C, Li J, et al. The diagnostic utility of novel immunohistochemical marker ERG in the workup of prostate biopsies with "atypical glands suspicious for cancer". Am J Surg Pathol. 2011; 35: 608-614.
    • (2011) Am J Surg Pathol , vol.35 , pp. 608-614
    • He, H.1    Magi-Galluzzi, C.2    Li, J.3
  • 37
    • 77950198794 scopus 로고    scopus 로고
    • Atypical cribriform lesions of the prostate: Relationship to prostatic carcinoma and implication for diagnosis in prostate biopsies
    • Shah RB, Magi-Galluzzi C, Han B, et al. Atypical cribriform lesions of the prostate: relationship to prostatic carcinoma and implication for diagnosis in prostate biopsies. Am J Surg Pathol. 2010; 34: 470-477.
    • (2010) Am J Surg Pathol , vol.34 , pp. 470-477
    • Shah, R.B.1    Magi-Galluzzi, C.2    Han, B.3
  • 38
    • 84862588002 scopus 로고    scopus 로고
    • Atypical cribriform lesions of the prostate: Clinical significance, differential diagnosis and current concept of intraductal carcinoma of the prostate
    • Shah RB, Zhou M. Atypical cribriform lesions of the prostate: clinical significance, differential diagnosis and current concept of intraductal carcinoma of the prostate. Adv Anat Pathol. 2012; 19: 270-278.
    • (2012) Adv Anat Pathol , vol.19 , pp. 270-278
    • Shah, R.B.1    Zhou, M.2
  • 39
    • 32044450042 scopus 로고    scopus 로고
    • Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: Implications for patient care
    • Epstein JI, Herawi M. Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care. J Urol. 2006; 175: 820-834.
    • (2006) J Urol , vol.175 , pp. 820-834
    • Epstein, J.I.1    Herawi, M.2
  • 40
    • 38049123346 scopus 로고    scopus 로고
    • Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
    • Attard G, Clark J, Ambroisine L, et al. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene. 2008; 27: 253-263.
    • (2008) Oncogene , vol.27 , pp. 253-263
    • Attard, G.1    Clark, J.2    Ambroisine, L.3
  • 41
    • 84867011997 scopus 로고    scopus 로고
    • Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma
    • Wang WL, Patel NR, Caragea M, et al. Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma. Mod Pathol. 2012; 25: 1378-1383.
    • (2012) Mod Pathol , vol.25 , pp. 1378-1383
    • Wang, W.L.1    Patel, N.R.2    Caragea, M.3
  • 42
    • 79953059276 scopus 로고    scopus 로고
    • ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma
    • Miettinen M, Wang ZF, Paetau A, et al. ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma. Am J Surg Pathol. 2011; 35: 432-441.
    • (2011) Am J Surg Pathol , vol.35 , pp. 432-441
    • Miettinen, M.1    Wang, Z.F.2    Paetau, A.3
  • 43
    • 84865359787 scopus 로고    scopus 로고
    • High level of Etsrelated gene expression has high specificity for prostate cancer: A tissue microarray study of 11 483 cancers
    • Minner S, Luebke AM, Kluth M, et al. High level of Etsrelated gene expression has high specificity for prostate cancer: a tissue microarray study of 11 483 cancers. Histopathology. 2012; 61: 445-453.
    • (2012) Histopathology , vol.61 , pp. 445-453
    • Minner, S.1    Luebke, A.M.2    Kluth, M.3
  • 44
    • 78649987427 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion in small cell carcinoma of the prostate
    • Guo CC, Dancer JY, Wang Y, et al. TMPRSS2-ERG gene fusion in small cell carcinoma of the prostate. Hum Pathol. 2011; 42: 11-17.
    • (2011) Hum Pathol , vol.42 , pp. 11-17
    • Guo, C.C.1    Dancer, J.Y.2    Wang, Y.3
  • 45
    • 69549135270 scopus 로고    scopus 로고
    • Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma
    • Han B, Mehra R, Suleman K, et al. Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma. Mod Pathol. 2009; 22: 1176-1185.
    • (2009) Mod Pathol , vol.22 , pp. 1176-1185
    • Han, B.1    Mehra, R.2    Suleman, K.3
  • 46
    • 33847105565 scopus 로고    scopus 로고
    • Expression of TMPRSS2: ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression
    • Nam RK, Sugar L, Wang Z, et al. Expression of TMPRSS2: ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression. Cancer Biol Ther. 2007; 6: 40-45.
    • (2007) Cancer Biol Ther , vol.6 , pp. 40-45
    • Nam, R.K.1    Sugar, L.2    Wang, Z.3
  • 47
    • 34248510706 scopus 로고    scopus 로고
    • TMPRSS2: ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
    • Demichelis F, Fall K, Perner S, et al. TMPRSS2: ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene. 2007; 26: 4596-4599.
    • (2007) Oncogene , vol.26 , pp. 4596-4599
    • Demichelis, F.1    Fall, K.2    Perner, S.3
  • 48
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, et al. TMPRSS2- ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res. 2009; 69: 1400-1406.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3
  • 49
    • 70350231922 scopus 로고    scopus 로고
    • Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer
    • Hermans KG, Boormans JL, Gasi D, et al. Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer. Clin Cancer Res. 2009; 15: 6398-6403.
    • (2009) Clin Cancer Res , vol.15 , pp. 6398-6403
    • Hermans, K.G.1    Boormans, J.L.2    Gasi, D.3
  • 50
    • 84866172302 scopus 로고    scopus 로고
    • The TMPRSS2: ERG rearrangement ERG expression and prostate cancer outcomes: A cohort study and meta-analysis
    • Pettersson A, Graff RE, Bauer SR, et al. The TMPRSS2: ERG rearrangement, ERG expression, and prostate cancer outcomes: a cohort study and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2012; 21: 1497-1509.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , pp. 1497-1509
    • Pettersson, A.1    Graff, R.E.2    Bauer, S.R.3
  • 51
    • 80052841071 scopus 로고    scopus 로고
    • ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy
    • Minner S, Enodien M, Sirma H, et al. ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res. 2011; 17: 5878-5888.
    • (2011) Clin Cancer Res , vol.17 , pp. 5878-5888
    • Minner, S.1    Enodien, M.2    Sirma, H.3
  • 52
    • 84857781655 scopus 로고    scopus 로고
    • ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer
    • Hoogland AM, Jenster G, van Weerden WM, et al. ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer. Mod Pathol. 2012; 25: 471-479.
    • (2012) Mod Pathol , vol.25 , pp. 471-479
    • Hoogland, A.M.1    Jenster, G.2    Van Weerden, W.M.3
  • 53
    • 76949106361 scopus 로고    scopus 로고
    • Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
    • Reid AH, Attard G, Ambroisine L, et al. Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. Br J Cancer. 2010; 102: 678-684.
    • (2010) Br J Cancer , vol.102 , pp. 678-684
    • Reid, A.H.1    Attard, G.2    Ambroisine, L.3
  • 54
    • 56649091295 scopus 로고    scopus 로고
    • Absence of TMPRSS2: ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
    • Yoshimoto M, Joshua AM, Cunha IW, et al. Absence of TMPRSS2: ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Mod Pathol. 2008; 21: 1451-1460.
    • (2008) Mod Pathol , vol.21 , pp. 1451-1460
    • Yoshimoto, M.1    Joshua, A.M.2    Cunha, I.W.3
  • 55
    • 79955968629 scopus 로고    scopus 로고
    • Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
    • Brenner JC, Ateeq B, Li Y, et al. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell. 2011; 19: 664-678.
    • (2011) Cancer Cell , vol.19 , pp. 664-678
    • Brenner, J.C.1    Ateeq, B.2    Li, Y.3
  • 56
    • 33748937011 scopus 로고    scopus 로고
    • Whole-pelvis "mini-pelvis, " or prostate-only external beam radiotherapy after neoadjuvant and concurrent hormonal therapy in patients treated in the Radiation Therapy Oncology Group 9413 trial
    • Roach M III, DeSilvio M, Valicenti R, et al. Whole-pelvis, "mini-pelvis, " or prostate-only external beam radiotherapy after neoadjuvant and concurrent hormonal therapy in patients treated in the Radiation Therapy Oncology Group 9413 trial. Int J Radiat Oncol Biol Phys. 2006; 66: 647-653.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 647-653
    • Roach III, M.1    Desilvio, M.2    Valicenti, R.3


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