Comparison of the basal cell-specific markers, 34βE12 and p63, in the diagnosis of prostate cancer

American Journal of Surgical Pathology

Volumn 26, Issue 9, 2002, Pages 1161-1168

  Shah, Rajal B ^a   Zhou, Ming ^a   LeBlanc, Michele ^a   Snyder, Matthew ^a   Rubin, Mark A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

34 E12 and p63; Basal cell specific markers; Prostate carcinoma

Indexed keywords

CELL MARKER; CYTOKERATIN ANTIBODY; MONOCLONAL ANTIBODY; PROTEIN P63 ANTIBODY; UNCLASSIFIED DRUG;

ACINAR CELL; ARTICLE; BASAL CELL; CELL PROLIFERATION; CLINICAL EXAMINATION; COMPARATIVE STUDY; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; PROSTATE CANCER; PROSTATE HYPERTROPHY; SECRETORY CELL; TRANSURETHRAL RESECTION;

ADENOCARCINOMA; BIOPSY, NEEDLE; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; MALE; MEMBRANE PROTEINS; MOLECULAR WEIGHT; PHOSPHOPROTEINS; PROSTATE; PROSTATIC NEOPLASMS; REPRODUCIBILITY OF RESULTS; STAINING AND LABELING; TRANS-ACTIVATORS; TRANSURETHRAL RESECTION OF PROSTATE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 0036723906     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200209000-00006     Document Type: Article

References (18)

1. p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast
2. Keratin immunoreactivity in the benign and neoplastic human prostate
3. Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: Results of a multicenter clinical trial of 6,630 men
4. Postatrophic hyperplasia of the prostate: A histologic mimic of prostatic adenocarcinoma
5. Anticytokeratin antibody 34 beta E12 staining in prostate carcinoma
6. Monoclonal antibodies to human intermediate filament proteins: II. Distribution of filament proteins in normal human tissues
7. Use of keratin 903 as an adjunct in the diagnosis of prostate carcinoma
8. Limiting the diagnosis of atypical small glandular proliferations in needle biopsies of the prostate by the use of immunohistochemistry
9. Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium
10. Usefulness of immunoperoxidase staining with high-molecular weight cytokeratin in the differential diagnosis of small-acinar lesions of the prostate gland
11. p63 protein expression is rare in prostate adenocarcinoma: Implications for cancer diagnosis and carcinogenesis
12. Cribriform carcinoma of the prostate and cribriform prostatic intraepithelial neoplasia: Incidence and clinical implications
13. p63 is a prostate basal cell marker and is required for prostate development
14. Discriminant staining pattern of small glandular and preneoplastic lesions of the prostate using high molecular weight cytokeratin antibody: A study of 301 consecutive needle biopsies
15. Effect of formalin fixation and epitope retrieval techniques on antibody 34betaE12 immunostaining of prostatic tissues
16. The utility of basal cell-specific anticytokeratin antibody (34 beta E12) in the diagnosis of prostate cancer: A review of 228 cases
17. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development