Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2365-2375

  Yang, Lu ^a   Li, Yun ^a   Ding, Yi ^a   Choi, Kyoung Soo ^a   Kazim, A Latif ^a   Zhang, Yuesheng ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYL TERMINUS; CYTOSOLIC ENZYMES; DI-PEPTIDES; DNA SYNTHESISS; ENZYMATIC ACTIVITIES; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; EXTRACELLULAR SPACE; SIGNALING PROTEINS; TRANSMEMBRANE PRECURSORS;

AMINO ACIDS; TISSUE;

LIGANDS;

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROLINE DIPEPTIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYCLOOXYGENASE 2 GENE; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ANIMALS; CELL LINE; CELL MEMBRANE; CYCLOOXYGENASE 2; CYTOSOL; DIPEPTIDASES; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; MALE; MICE; MICE, INBRED C57BL; MUTATION; PROTEIN BINDING; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84873829861     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.429159     Document Type: Article

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