Novel insights into phosgene-induced acute lung injury in rats: Role of dysregulated cardiopulmonary reflexes and nitric oxide in lung edema pathogenesis

Toxicological Sciences

Volumn 131, Issue 2, 2013, Pages 612-628

  Li, Wenli ^a   Liu, Fangfang ^b   Wang, Chen ^c   Truebel, Hubert ^d   Pauluhn, Juergen ^d  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c BEIJING HOSPITAL   (China)

^d BAYER PHARMA AG   (Germany)

Author keywords

Exhaled nitric oxide; Lung function; Nitric oxidase synthetase inhibition; Pulmonary irritation

Indexed keywords

BIOLOGICAL MARKER; CARBON DIOXIDE; HEMOGLOBIN; N(G) NITROARGININE METHYL ESTER; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE; PHOSGENE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; APNEA; ARTICLE; BLOOD SAMPLING; BRADYCARDIA; BREATHING REFLEX; CARDIOPULMONARY FUNCTION; CARDIOPULMONARY HEMODYNAMICS; CONTROLLED STUDY; DRUG EFFICACY; ENVIRONMENTAL EXPOSURE; EXHALATION; HEMOGLOBIN BLOOD LEVEL; HYPOTHERMIA; INHALATION; LUNG EDEMA; LUNG LAVAGE; MALE; NONHUMAN; PATHOGENESIS; RAT; VAGUS NERVE;

ACUTE LUNG INJURY; ANIMALS; BODY TEMPERATURE; BREATH TESTS; ELECTROCARDIOGRAPHY; HEART; HEART RATE; LUNG; MALE; NITRIC OXIDE; PHOSGENE; PULMONARY EDEMA; RATS; RATS, WISTAR;

EID: 84873815044     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs317     Document Type: Article

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