N-acetylcysteine attenuates phosgene-induced acute lung injury via up-regulation of Nrf2 expression

Inhalation Toxicology

Volumn 22, Issue 7, 2010, Pages 535-542

  Ji, Lin ^a   Liu, Rui ^a   Zhang, Xiao Di ^a   Chen, Hong Li ^a   Bai, Hua ^a   Wang, Xin ^a   Zhao, Hai Long ^a   Liang, Xin ^a   Hai, Chun Xu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury; Glutathione; N acetylcysteine; Nrf2; Phosgene

Indexed keywords

ACETYLCYSTEINE; CATALASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; PHOSGENE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; GLUTATHIONE METABOLISM; LIPID PEROXIDATION; LOW DRUG DOSE; LUNG EDEMA; LUNG WEIGHT; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; UPREGULATION;

ACETYLCYSTEINE; ACUTE LUNG INJURY; ANIMALS; GLUTATHIONE; GLUTATHIONE REDUCTASE; MALE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSGENE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 77952858846     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958370903525183     Document Type: Article

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