Multidrug resistance-associated proteins are involved in the transport of the glutathione conjugates of the ultimate carcinogen of benzo[a]pyrene in human Caco-2 cells

Archives of Toxicology

Volumn 87, Issue 2, 2013, Pages 269-280

  Hessel, Stefanie ^a   John, Andrea ^b   Seidel, Albrecht ^b   Lampen, Alfonso ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b Prof Dr Gernot Grimmer Foundation   (Germany)

Author keywords

Benzo a pyrene; Caco 2 cells; Multidrug resistance associated proteins; Polycyclic aromatic hydrocarbons

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER C1; ABC TRANSPORTER C2; ABC TRANSPORTER C3; BENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; GLUTATHIONE; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; DETOXIFICATION; EXCRETION; HUMAN; HUMAN CELL; INTESTINE CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSPORT KINETICS;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CARCINOGENS; DRUG RESISTANCE, MULTIPLE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; TIME FACTORS;

EID: 84873742401     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0917-0     Document Type: Article

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