메뉴 건너뛰기




Volumn 43, Issue 3-4, 2013, Pages 225-231

The hookworm pharmacopoeia for inflammatory diseases

Author keywords

Asthma; Excretory secretory; Hookworm; Hygiene hypothesis; Inflammatory bowel disease; Therapeutic

Indexed keywords

CALRETICULIN; EXCRETORY SECRETORY PROTEIN; GLYCOPROTEIN; HELMINTH PROTEIN; LOW MOLECULAR WEIGHT HEPARIN; NEMATODE ANTICOAGULANT PEPTIDE C2; NEUTROPHIL INHIBITORY FACTOR; PARASITE ANTIGEN; SECRETORY PROTEIN; TISSUE PLASMINOGEN ACTIVATOR; UK 279276; UNCLASSIFIED DRUG;

EID: 84873732487     PISSN: 00207519     EISSN: 18790135     Source Type: Journal    
DOI: 10.1016/j.ijpara.2012.11.005     Document Type: Article
Times cited : (41)

References (92)
  • 2
    • 84859092357 scopus 로고    scopus 로고
    • Australian Centre for Asthma Monitoring, Canberra, Australia
    • Australian Centre for Asthma Monitoring Asthma in Australia 2011 2011, Canberra, Australia.
    • (2011) Asthma in Australia 2011
  • 3
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes P.J. Immunology of asthma and chronic obstructive pulmonary disease. Nat. Rev. Immunol. 2008, 8:183-192.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 183-192
    • Barnes, P.J.1
  • 6
    • 70449730700 scopus 로고    scopus 로고
    • Immunologic profiles of persons recruited for a randomized, placebo-controlled clinical trial of hookworm infection
    • Blount D., Hooi D., Feary J., Venn A., Telford G., Brown A., Britton J., Pritchard D. Immunologic profiles of persons recruited for a randomized, placebo-controlled clinical trial of hookworm infection. Am. J. Trop. Med. Hyg. 2009, 81:911-916.
    • (2009) Am. J. Trop. Med. Hyg. , vol.81 , pp. 911-916
    • Blount, D.1    Hooi, D.2    Feary, J.3    Venn, A.4    Telford, G.5    Brown, A.6    Britton, J.7    Pritchard, D.8
  • 7
    • 0033791336 scopus 로고    scopus 로고
    • Chronic immune activation associated with intestinal helminth infections results in impaired signal transduction and anergy
    • Borkow G., Leng Q., Weisman Z., Stein M., Galai N., Kalinkovich A., Bentwich Z. Chronic immune activation associated with intestinal helminth infections results in impaired signal transduction and anergy. J. Clin. Invest. 2000, 106:1053-1060.
    • (2000) J. Clin. Invest. , vol.106 , pp. 1053-1060
    • Borkow, G.1    Leng, Q.2    Weisman, Z.3    Stein, M.4    Galai, N.5    Kalinkovich, A.6    Bentwich, Z.7
  • 9
    • 0037135531 scopus 로고    scopus 로고
    • Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase
    • Buddai S.K., Toulokhonova L., Bergum P.W., Vlasuk G.P., Krishnaswamy S. Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase. J. Biol. Chem. 2002, 277:26689-26698.
    • (2002) J. Biol. Chem. , vol.277 , pp. 26689-26698
    • Buddai, S.K.1    Toulokhonova, L.2    Bergum, P.W.3    Vlasuk, G.P.4    Krishnaswamy, S.5
  • 12
    • 0029014045 scopus 로고
    • Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa
    • Cappello M., Vlasuk G.P., Bergum P.W., Huang S., Hotez P.J. Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa. Proc. Natl. Acad. Sci. USA 1995, 92:6152-6156.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6152-6156
    • Cappello, M.1    Vlasuk, G.P.2    Bergum, P.W.3    Huang, S.4    Hotez, P.J.5
  • 13
    • 2542486456 scopus 로고    scopus 로고
    • Asthma: mechanisms of disease persistence and progression
    • Cohn L., Elias J.A., Chupp G.L. Asthma: mechanisms of disease persistence and progression. Ann. Rev. Immunol. 2004, 22:789-815.
    • (2004) Ann. Rev. Immunol. , vol.22 , pp. 789-815
    • Cohn, L.1    Elias, J.A.2    Chupp, G.L.3
  • 15
    • 29244453651 scopus 로고    scopus 로고
    • A proof of concept study establishing Necator americanus in Crohn's patients and reservoir donors
    • Croese J., O'Neil J., Masson J., Cooke S., Melrose W., Pritchard D., Speare R. A proof of concept study establishing Necator americanus in Crohn's patients and reservoir donors. Gut 2006, 55:136-137.
    • (2006) Gut , vol.55 , pp. 136-137
    • Croese, J.1    O'Neil, J.2    Masson, J.3    Cooke, S.4    Melrose, W.5    Pritchard, D.6    Speare, R.7
  • 16
    • 77949329252 scopus 로고    scopus 로고
    • The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells
    • Cuellar C., Wu W., Mendez S. The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells. PLoS Neglect. Trop. Dis. 2009, 3:e439.
    • (2009) PLoS Neglect. Trop. Dis. , vol.3
    • Cuellar, C.1    Wu, W.2    Mendez, S.3
  • 21
    • 66749178498 scopus 로고    scopus 로고
    • Safety of hookworm infection in individuals with measurable airway responsiveness: a randomized placebo-controlled feasibility study
    • Feary J., Venn A., Brown A., Hooi D., Falcone F.H., Mortimer K., Pritchard D.I., Britton J. Safety of hookworm infection in individuals with measurable airway responsiveness: a randomized placebo-controlled feasibility study. Clin. Exp. Allerg. 2009, 39:1060-1068.
    • (2009) Clin. Exp. Allerg. , vol.39 , pp. 1060-1068
    • Feary, J.1    Venn, A.2    Brown, A.3    Hooi, D.4    Falcone, F.H.5    Mortimer, K.6    Pritchard, D.I.7    Britton, J.8
  • 23
    • 57349103139 scopus 로고    scopus 로고
    • Investigation of the role of cholera toxin in assisting the initiation of the antigen-specific Th2 response
    • Feng B.S., Zheng P.Y., Chen X., Liao X.Q., Yang P.C. Investigation of the role of cholera toxin in assisting the initiation of the antigen-specific Th2 response. Immunol. Invest. 2008, 37:782-797.
    • (2008) Immunol. Invest. , vol.37 , pp. 782-797
    • Feng, B.S.1    Zheng, P.Y.2    Chen, X.3    Liao, X.Q.4    Yang, P.C.5
  • 25
    • 79953307223 scopus 로고    scopus 로고
    • Helminths and multiple sclerosis: will old friends give us new treatments for MS?
    • Fleming J.O. Helminths and multiple sclerosis: will old friends give us new treatments for MS?. J. Neuroimmunol. 2011, 233:3-5.
    • (2011) J. Neuroimmunol. , vol.233 , pp. 3-5
    • Fleming, J.O.1
  • 26
    • 58149232412 scopus 로고    scopus 로고
    • Do helminth parasites protect against atopy and allergic disease?
    • Flohr C., Quinnell R.J., Britton J. Do helminth parasites protect against atopy and allergic disease?. Clin. Exp. Allerg. 2009, 39:20-32.
    • (2009) Clin. Exp. Allerg. , vol.39 , pp. 20-32
    • Flohr, C.1    Quinnell, R.J.2    Britton, J.3
  • 27
    • 84857046993 scopus 로고    scopus 로고
    • The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agent
    • Furman B.L. The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agent. Toxicon 2012, 59:464-471.
    • (2012) Toxicon , vol.59 , pp. 464-471
    • Furman, B.L.1
  • 31
  • 32
    • 84860655039 scopus 로고    scopus 로고
    • Innate and adaptive immune responses in asthma
    • Holgate S.T. Innate and adaptive immune responses in asthma. Nat. Med. 2012, 18:673-683.
    • (2012) Nat. Med. , vol.18 , pp. 673-683
    • Holgate, S.T.1
  • 36
    • 0035987310 scopus 로고    scopus 로고
    • Negative association of Enterobius infestation with asthma and rhinitis in primary school children in Taipei
    • Huang S.L., Tsai P.F., Yeh Y.F. Negative association of Enterobius infestation with asthma and rhinitis in primary school children in Taipei. Clin. Exp. Allerg. 2002, 32:1029-1032.
    • (2002) Clin. Exp. Allerg. , vol.32 , pp. 1029-1032
    • Huang, S.L.1    Tsai, P.F.2    Yeh, Y.F.3
  • 37
    • 0032579788 scopus 로고    scopus 로고
    • Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat
    • Jiang N., Chopp M., Chahwala S. Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat. Brain Res. 1998, 788:25-34.
    • (1998) Brain Res. , vol.788 , pp. 25-34
    • Jiang, N.1    Chopp, M.2    Chahwala, S.3
  • 38
    • 84859918761 scopus 로고    scopus 로고
    • Probiotics in the management of inflammatory bowel disease: a systematic review of intervention studies in adult patients
    • Jonkers D., Penders J., Masclee A., Pierik M. Probiotics in the management of inflammatory bowel disease: a systematic review of intervention studies in adult patients. Drugs 2012, 72:803-823.
    • (2012) Drugs , vol.72 , pp. 803-823
    • Jonkers, D.1    Penders, J.2    Masclee, A.3    Pierik, M.4
  • 39
    • 84859879397 scopus 로고    scopus 로고
    • RORgammat-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation
    • Kanai T., Mikami Y., Sujino T., Hisamatsu T., Hibi T. RORgammat-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation. Mucosal Immunol. 2012, 5:240-247.
    • (2012) Mucosal Immunol. , vol.5 , pp. 240-247
    • Kanai, T.1    Mikami, Y.2    Sujino, T.3    Hisamatsu, T.4    Hibi, T.5
  • 40
  • 41
    • 0242694372 scopus 로고    scopus 로고
    • Acute stroke therapy by inhibition of neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke
    • Krams M., Lees K.R., Hacke W., Grieve A.P., Orgogozo J.M., Ford G.A. Acute stroke therapy by inhibition of neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke. Stroke 2003, 34:2543-2548.
    • (2003) Stroke , vol.34 , pp. 2543-2548
    • Krams, M.1    Lees, K.R.2    Hacke, W.3    Grieve, A.P.4    Orgogozo, J.M.5    Ford, G.A.6
  • 42
    • 0035800075 scopus 로고    scopus 로고
    • Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement
    • Lee A., Agnelli G., Buller H., Ginsberg J., Heit J., Rote W., Vlasuk G., Costantini L., Julian J., Comp P., van Der Meer J., Piovella F., Raskob G., Gent M. Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement. Circulation 2001, 104:74-78.
    • (2001) Circulation , vol.104 , pp. 74-78
    • Lee, A.1    Agnelli, G.2    Buller, H.3    Ginsberg, J.4    Heit, J.5    Rote, W.6    Vlasuk, G.7    Costantini, L.8    Julian, J.9    Comp, P.10    van Der Meer, J.11    Piovella, F.12    Raskob, G.13    Gent, M.14
  • 43
    • 33748317870 scopus 로고    scopus 로고
    • Asthma and current intestinal parasite infection: systematic review and meta-analysis
    • Leonardi-Bee J., Pritchard D., Britton J. Asthma and current intestinal parasite infection: systematic review and meta-analysis. Am. J. Resp. Crit. Care Med. 2006, 174:514-523.
    • (2006) Am. J. Resp. Crit. Care Med. , vol.174 , pp. 514-523
    • Leonardi-Bee, J.1    Pritchard, D.2    Britton, J.3
  • 44
    • 85047688324 scopus 로고    scopus 로고
    • Alterations in the porcine colon microbiota induced by the gastrointestinal nematode Trichuris suis
    • Li R.W., Wu S., Li W., Navarro K., Couch R.D., Hill D., Urban J.F. Alterations in the porcine colon microbiota induced by the gastrointestinal nematode Trichuris suis. Infect. Immun. 2012, 80:2150-2157.
    • (2012) Infect. Immun. , vol.80 , pp. 2150-2157
    • Li, R.W.1    Wu, S.2    Li, W.3    Navarro, K.4    Couch, R.D.5    Hill, D.6    Urban, J.F.7
  • 45
    • 1342308180 scopus 로고    scopus 로고
    • Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
    • Ling E.M., Smith T., Nguyen X.D., Pridgeon C., Dallman M., Arbery J., Carr V.A., Robinson D.S. Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004, 363:608-615.
    • (2004) Lancet , vol.363 , pp. 608-615
    • Ling, E.M.1    Smith, T.2    Nguyen, X.D.3    Pridgeon, C.4    Dallman, M.5    Arbery, J.6    Carr, V.A.7    Robinson, D.S.8
  • 49
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy K.J., Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011, 474:298-306.
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 50
    • 77954644772 scopus 로고    scopus 로고
    • The immunology of human hookworm infections
    • McSorley H.J., Loukas A. The immunology of human hookworm infections. Parasite Immunol. 2010, 32:549-559.
    • (2010) Parasite Immunol. , vol.32 , pp. 549-559
    • McSorley, H.J.1    Loukas, A.2
  • 55
    • 0028020563 scopus 로고
    • Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18
    • Muchowski P.J., Zhang L., Chang E.R., Soule H.R., Plow E.F., Moyle M. Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18. J. Biol. Chem. 1994, 269:26419-26423.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26419-26423
    • Muchowski, P.J.1    Zhang, L.2    Chang, E.R.3    Soule, H.R.4    Plow, E.F.5    Moyle, M.6
  • 56
    • 59149091643 scopus 로고    scopus 로고
    • Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum
    • Mulvenna J., Hamilton B., Nagaraj S.H., Smyth D., Loukas A., Gorman J.J. Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum. Mol. Cell. Proteomics 2009, 8:109-121.
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 109-121
    • Mulvenna, J.1    Hamilton, B.2    Nagaraj, S.H.3    Smyth, D.4    Loukas, A.5    Gorman, J.J.6
  • 57
    • 0032808666 scopus 로고    scopus 로고
    • Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum
    • Nguyen T.T., Qasim M.A., Morris S., Lu C.C., Hill D., Laskowski M., Sakanari J.A. Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum. Mol. Biochem. Parasitol. 1999, 102:79-89.
    • (1999) Mol. Biochem. Parasitol. , vol.102 , pp. 79-89
    • Nguyen, T.T.1    Qasim, M.A.2    Morris, S.3    Lu, C.C.4    Hill, D.5    Laskowski, M.6    Sakanari, J.A.7
  • 58
    • 34447508256 scopus 로고    scopus 로고
    • Hirudin - the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond. A historical piece
    • Nowak G., Schror K. Hirudin - the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond. A historical piece. Thromb. Haem. 2007, 98:116-119.
    • (2007) Thromb. Haem. , vol.98 , pp. 116-119
    • Nowak, G.1    Schror, K.2
  • 61
    • 0002809726 scopus 로고
    • Course of egg output over a 15year period in a case of experimentally induced necatoriasis americanus, in the absence of hyperinfection
    • Palmer E.D. Course of egg output over a 15year period in a case of experimentally induced necatoriasis americanus, in the absence of hyperinfection. Am. J. Trop. Med. Hyg. 1955, 4:756-757.
    • (1955) Am. J. Trop. Med. Hyg. , vol.4 , pp. 756-757
    • Palmer, E.D.1
  • 62
    • 58149289547 scopus 로고    scopus 로고
    • Systematic review of worldwide variations of the prevalence of wheezing symptoms in children
    • Patel S.P., Jarvelin M.R., Little M.P. Systematic review of worldwide variations of the prevalence of wheezing symptoms in children. Environ. Health 2008, 7:57.
    • (2008) Environ. Health , vol.7 , pp. 57
    • Patel, S.P.1    Jarvelin, M.R.2    Little, M.P.3
  • 63
    • 77955933088 scopus 로고    scopus 로고
    • Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites
    • Pearson M.S., Ranjit N., Loukas A. Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites. Biol. Chem. 2010, 391:901-911.
    • (2010) Biol. Chem. , vol.391 , pp. 901-911
    • Pearson, M.S.1    Ranjit, N.2    Loukas, A.3
  • 64
    • 0034896332 scopus 로고    scopus 로고
    • Parasite-specific antibody and cellular immune responses in human infected with Necator americanus and Oesophagostomum bifurcum
    • Pit D.S., Polderman A.M., Baeta S., Schulz-Key H., Soboslay P.T. Parasite-specific antibody and cellular immune responses in human infected with Necator americanus and Oesophagostomum bifurcum. Parasitol. Res. 2001, 87:722-729.
    • (2001) Parasitol. Res. , vol.87 , pp. 722-729
    • Pit, D.S.1    Polderman, A.M.2    Baeta, S.3    Schulz-Key, H.4    Soboslay, P.T.5
  • 65
    • 79951799441 scopus 로고    scopus 로고
    • Food allergy: riding the second wave of the allergy epidemic
    • Prescott S., Allen K.J. Food allergy: riding the second wave of the allergy epidemic. Pediatr. Allerg. Immunol. 2011, 22:155-160.
    • (2011) Pediatr. Allerg. Immunol. , vol.22 , pp. 155-160
    • Prescott, S.1    Allen, K.J.2
  • 66
    • 0035305904 scopus 로고    scopus 로고
    • Is Necator americanus approaching a mutualistic symbiotic relationship with humans?
    • Pritchard D.I., Brown A. Is Necator americanus approaching a mutualistic symbiotic relationship with humans?. Trends Parasitol. 2001, 17:169-172.
    • (2001) Trends Parasitol. , vol.17 , pp. 169-172
    • Pritchard, D.I.1    Brown, A.2
  • 69
    • 3242776207 scopus 로고    scopus 로고
    • Immune responses in human necatoriasis: association between interleukin-5 responses and resistance to reinfection
    • Quinnell R.J., Pritchard D.I., Raiko A., Brown A.P., Shaw M.A. Immune responses in human necatoriasis: association between interleukin-5 responses and resistance to reinfection. J. Infect. Dis. 2004, 190:430-438.
    • (2004) J. Infect. Dis. , vol.190 , pp. 430-438
    • Quinnell, R.J.1    Pritchard, D.I.2    Raiko, A.3    Brown, A.P.4    Shaw, M.A.5
  • 72
    • 84857052430 scopus 로고    scopus 로고
    • Hygiene hypothesis and autoimmune diseases
    • Rook G.A. Hygiene hypothesis and autoimmune diseases. Clin. Rev. Allerg. Immunol. 2012, 42:5-15.
    • (2012) Clin. Rev. Allerg. Immunol. , vol.42 , pp. 5-15
    • Rook, G.A.1
  • 76
    • 70649092298 scopus 로고    scopus 로고
    • Celiac disease: from pathogenesis to novel therapies
    • Schuppan D., Junker Y., Barisani D. Celiac disease: from pathogenesis to novel therapies. Gastroenterology 2009, 137:1912-1933.
    • (2009) Gastroenterology , vol.137 , pp. 1912-1933
    • Schuppan, D.1    Junker, Y.2    Barisani, D.3
  • 79
    • 76649100413 scopus 로고    scopus 로고
    • Chronic helminth infections protect against allergic diseases by active regulatory processes
    • Smits H.H., Everts B., Hartgers F.C., Yazdanbakhsh M. Chronic helminth infections protect against allergic diseases by active regulatory processes. Curr. Allerg. Asthma Rep. 2010, 10:3-12.
    • (2010) Curr. Allerg. Asthma Rep. , vol.10 , pp. 3-12
    • Smits, H.H.1    Everts, B.2    Hartgers, F.C.3    Yazdanbakhsh, M.4
  • 81
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and household size
    • Strachan D.P. Hay fever, hygiene, and household size. Br. Med. J. 1989, 299:1259-1260.
    • (1989) Br. Med. J. , vol.299 , pp. 1259-1260
    • Strachan, D.P.1
  • 82
  • 85
    • 0242438144 scopus 로고    scopus 로고
    • Pharmacokinetics and anticoagulant properties of the factor VIIa-tissue factor inhibitor recombinant Nematode Anticoagulant Protein c2 following subcutaneous administration in man. Dependence on the stoichiometric binding to circulating factor X
    • Vlasuk G.P., Bradbury A., Lopez-Kinninger L., Colon S., Bergum P.W., Maki S., Rote W.E. Pharmacokinetics and anticoagulant properties of the factor VIIa-tissue factor inhibitor recombinant Nematode Anticoagulant Protein c2 following subcutaneous administration in man. Dependence on the stoichiometric binding to circulating factor X. Thromb. Haem. 2003, 90:803-812.
    • (2003) Thromb. Haem. , vol.90 , pp. 803-812
    • Vlasuk, G.P.1    Bradbury, A.2    Lopez-Kinninger, L.3    Colon, S.4    Bergum, P.W.5    Maki, S.6    Rote, W.E.7
  • 86
    • 77952058969 scopus 로고    scopus 로고
    • Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation
    • Wang Z., Abubucker S., Martin J., Wilson R.K., Hawdon J., Mitreva M. Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation. BMC Genomics 2010, 11:307.
    • (2010) BMC Genomics , vol.11 , pp. 307
    • Wang, Z.1    Abubucker, S.2    Martin, J.3    Wilson, R.K.4    Hawdon, J.5    Mitreva, M.6
  • 87
    • 61949233686 scopus 로고    scopus 로고
    • Helminths and the IBD hygiene hypothesis
    • Weinstock J.V., Elliott D.E. Helminths and the IBD hygiene hypothesis. Inflamm. Bowel Dis. 2009, 15:128-133.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 128-133
    • Weinstock, J.V.1    Elliott, D.E.2
  • 88
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Ann. Rev. Immunol. 1999, 17:255-281.
    • (1999) Ann. Rev. Immunol. , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 89
    • 27644501820 scopus 로고    scopus 로고
    • Immune responses following experimental human hookworm infection
    • Wright V., Bickle Q. Immune responses following experimental human hookworm infection. Clin. Exp. Immunol. 2005, 142:398-403.
    • (2005) Clin. Exp. Immunol. , vol.142 , pp. 398-403
    • Wright, V.1    Bickle, Q.2
  • 90
    • 0037134046 scopus 로고    scopus 로고
    • Allergy, parasites, and the hygiene hypothesis
    • Yazdanbakhsh M., Kremsner P.G., van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 2002, 296:490-494.
    • (2002) Science , vol.296 , pp. 490-494
    • Yazdanbakhsh, M.1    Kremsner, P.G.2    van Ree, R.3
  • 91
    • 0034924919 scopus 로고    scopus 로고
    • Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease
    • Yazdanbakhsh M., van den Biggelaar A., Maizels R.M. Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol. 2001, 22:372-377.
    • (2001) Trends Immunol. , vol.22 , pp. 372-377
    • Yazdanbakhsh, M.1    van den Biggelaar, A.2    Maizels, R.M.3
  • 92
    • 0038506990 scopus 로고    scopus 로고
    • Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke
    • Zhang L., Zhang Z.G., Zhang R.L., Lu M., Krams M., Chopp M. Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke. Stroke 2003, 34:1790-1795.
    • (2003) Stroke , vol.34 , pp. 1790-1795
    • Zhang, L.1    Zhang, Z.G.2    Zhang, R.L.3    Lu, M.4    Krams, M.5    Chopp, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.