25-Hydroxyvitamin D3 attenuates experimental periodontitis through downregulation of TLR4 and JAK1/STAT3 signaling in diabetic mice

Journal of Steroid Biochemistry and Molecular Biology

Volumn 135, Issue 1, 2013, Pages 43-50

  Wang, Qi ^a   Li, Hao ^a   Xie, Honghui ^a   Fu, Min ^a   Guo, Bin ^b   Ding, Yi ^a   Li, Wei ^a   Yu, Haiyang ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

25 Hydroxyvitamin D3; Diabetes; JAK1; Periodontitis; STAT3; TLR4

Indexed keywords

CALCIFEDIOL; GLYCOSYLATED HEMOGLOBIN; JANUS KINASE 1; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; JAK1 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ALVEOLAR BONE LOSS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PERIODONTITIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DIABETES MELLITUS; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; MOUTH MUCOSA; NONOBESE DIABETIC MOUSE; PHOSPHORYLATION;

MUS;

ALVEOLAR BONE LOSS; ANIMALS; BLOOD GLUCOSE; CALCIFEDIOL; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; DOWN-REGULATION; HEMOGLOBIN A, GLYCOSYLATED; JANUS KINASE 1; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MOUTH MUCOSA; PERIODONTITIS; PHOSPHORYLATION; RECEPTORS, CALCITRIOL; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

MLCS; MLOWN;

EID: 84873728236     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.01.008     Document Type: Article

References (45)

1. I. Chorbev, M. Sotirovska, and D. Mihajlov Virtual communities for diabetes chronic disease healthcare International Journal of Telemedicine and Applications 2011 2011 721654
2. P. Preshaw Periodontal disease and diabetes Journal of Dentistry 37 8 2009 S575 S577
3. S. Pacios, J. Kang, J. Galicia, K. Gluck, H. Patel, A. Ovaydi-Mandel, S. Petrov, F. Alawi, and D. Graves Diabetes aggravates periodontitis by limiting repair through enhanced inflammation FASEB Journal 26 4 2012 1423 1430
4. W. Sun, L. Chen, S. Zhang, Y. Wu, Y. Ren, and G. Qin Inflammatory cytokines, adiponectin, insulin resistance and metabolic control after periodontal intervention in patients with type 2 diabetes and chronic periodontitis Internal Medicine 50 15 2011 1569 1574
5. T. Suibhne, G. Cox, M. Healy, C. O'Morain, M. O'Sullivan, and Vitamin D deficiency in Crohn's disease: prevalence, risk factors and supplement use in an outpatient setting Journal of Crohn's and Colitis 6 2 2012 182 188
6. B. Lee, S. Park, and Y. Kim Age- and gender-specific associations between low serum 25-hydroxyvitamin D level and type 2 diabetes in the Korean general population: analysis of 2008-2009 Korean National Health and Nutrition Examination Survey data Asia Pacific Journal of Clinical Nutrition 21 4 2012 536 546
7. Y. Lou, F. Molnár, M. Peräkylä, S. Qiao, A. Kalueff, R. St-Arnaud, C. Carlberg, and P. Tuohimaa 25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand Journal of Steroid Biochemistry and Molecular Biology 118 3 2010 162 170
8. D. Bikle Vitamin D: newly discovered actions require reconsideration of physiologic requirements Trends in Endocrinology and Metabolism 21 6 2010 375 384
9. M. Hewison Vitamin D and the intracrinology of innate immunity Molecular and Cellular Endocrinology 321 2 2010 103 111
10. H. Cross, T. Nittke, and E. Kallay Colonic vitamin D metabolism: implications for the pathogenesis of inflammatory bowel disease and colorectal cancer Molecular and Cellular Endocrinology 347 1-2 2011 70 79
11. L. McMahon, K. Schwartz, O. Yilmaz, E. Brown, L. Ryan, and G. Diamond Vitamin D-mediated induction of innate immunity in gingival epithelial cells Infection and Immunity 79 6 2011 2250 2256
12. N. Rojo-Botello, A. García-Hernández, and L. Moreno-Fierros Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis Journal of Periodontal Research 47 1 2012 62 73
13. G. Murillo, V. Nagpal, N. Tiwari, R. Benya, and R. Mehta Actions of vitamin D are mediated by the TLR4 pathway in inflammation-induced colon cancer Journal of Steroid Biochemistry and Molecular Biology 121 1-2 2010 403 407
14. V. Walker, X. Zhang, I. Rastegar, P. Liu, B. Hollis, J. Adams, and R. Modlin Cord blood vitamin D status impacts innate immune responses Journal of Clinical Endocrinology and Metabolism 96 6 2011 1835 1843
15. X. Hu, J. Chen, L. Wang, and L. Ivashkiv Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation Journal of Leukocyte Biology 82 2 2007 237 243
16. J. de Souza, A. Nogueira, P. de Souza, J. Cirelli, G. Garlet, and C.J. Rossa Expression of suppressor of cytokine signaling 1 and 3 in ligature-induced periodontitis in rats Archives of Oral Biology 56 10 2011 1120 1128
17. S. Mao, Y. Park, Y. Hasegawa, G. Tribble, C. James, M. Handfield, M. Stavropoulos, O. Yilmaz, and R. Lamont Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalis Cellular Microbiology 9 8 2007 1997 2007
18. J. Silva, D. Ferrucci, L. Peroni, P. Abrahão, A. Salamene, C. Rossa-Junior, H. Carvalho, and D. Stach-Machado Sequential IL-23 and IL-17 and increased Mmp8 and Mmp14 expression characterize the progression of an experimental model of periodontal disease in type 1 diabetes Journal of Cellular Physiology 227 6 2012 2441 2450
19. R. Sulniute, T. Lindh, M. Wilczynska, J. Li, and T. Ny Plasmin is essential in preventing periodontitis in mice American Journal of Pathology 179 2 2011 819 828
20. H. Lee, J. Ju, S. Paul, J. So, A. DeCastro, A. Smolarek, M. Lee, C. Yang, H. Newmark, and N. Suh Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma Clinical Cancer Research 15 12 2009 4242 4249
21. D. Graves, and R. Kayal Diabetic complications and dysregulated innate immunity Frontiers in Bioscience 13 2008 1227 1239
22. I. Lamster, E. Lalla, W. Borgnakke, and G. Taylor The relationship between oral health and diabetes mellitus Journal of the American Dental Association 139 Suppl. 2008 19S 24S
23. D. Ekuni, T. Tomofuji, K. Irie, K. Kasuyama, M. Umakoshi, T. Azuma, N. Tamaki, T. Sanbe, Y. Endo, T. Yamamoto, T. Nishida, and M. Morita Effects of periodontitis on aortic insulin resistance in an obese rat model Laboratory Investigation 90 3 2010 348 359
24. E. Gurzov, and D. Eizirik Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction Trends in Cell Biology 21 7 2011 424 431
25. D. Graves, M. Oskoui, S. Volejnikova, G. Naguib, S. Cai, T. Desta, A. Kakouras, and Y. Jiang Tumor necrosis factor modulates fibroblast apoptosis, PMN recruitment, and osteoclast formation in response to P. gingivalis infection Journal of Dental Research 80 10 2001 1875 1879
26. M. Lechleitner, T. Koch, M. Herold, A. Dzien, and F. Hoppichler Tumour necrosis factor-alpha plasma level in patients with type 1 diabetes mellitus and its association with glycaemic control and cardiovascular risk factors Journal of Internal Medicine 248 1 2000 67 76
27. R. Górska, H. Gregorek, J. Kowalski, A. Laskus-Perendyk, M. Syczewska, and K. Madaliński Relationship between clinical parameters and cytokine profiles in inflamed gingival tissue and serum samples from patients with chronic periodontitis Journal of Clinical Periodontology 30 12 2003 1046 1052
28. Y. Gonzalez, M. Herrera, G. Soldevila, L. Garcia-Garcia, G. Fabián, E. Pérez-Armendariz, K. Bobadilla, S. Guzmán- Beltrán, E. Sada, and M. Torres High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes BMC Immunology 13 2012 19
29. S. Amar, K. Oyaisu, L. Li, and T. Van Dyke Moesin: a potential LPS receptor on human monocytes Journal of Endotoxin Research 7 4 2001 281 286
30. X. Zhou, J. Han, Y. Song, J. Zhang, and Z. Wang Serum levels of 25-hydroxyvitamin D, oral health and chronic obstructive pulmonary disease Journal of Clinical Periodontology 39 4 2012 350 356
31. X. Guillot, L. Semerano, N. Saidenberg-Kermanac'H., G. Falgarone, and M. Boissier Vitamin D and inflammation Joint, Bone, Spine 77 6 2010 552 557
32. Y. Zhang, D. Leung, B. Richers, Y. Liu, L. Remigio, D. Riches, and E. Goleva Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1 Journal of Immunology 188 5 2012 2127 2135
33. E. Shimada, H. Kataoka, Y. Miyazawa, M. Yamamoto, and T. Igarashi Lipoproteins of Actinomyces viscosus induce inflammatory responses through TLR2 in human gingival epithelial cells and macrophages Microbes and Infection 14 11 2012 916 921
34. R. Mahanonda, N. Sa-Ard-Iam, P. Rerkyen, A. Thitithanyanont, K. Subbalekha, and S. Pichyangkul MxA expression induced by α-defensin in healthy human periodontal tissue European Journal of Immunology 42 4 2012 946 956
35. J. Umeda, D. Demuth, E. Ando, M. Faveri, and M. Mayer Signaling transduction analysis in gingival epithelial cells after infection with Aggregatibacter actinomycetemcomitans Molecular Oral Microbiology 27 1 2012 23 33
36. J. Shin, and Y. Choi Treponema denticola suppresses expression of human beta-defensin-2 in gingival epithelial cells through inhibition of TNFalpha production and TLR2 activation Molecular Cell 29 4 2010 407 412
37. H. Kaur, A. Chien, and I. Jialal Hyperglycemia induces toll like receptor 4 expression and activity in mouse mesangial cells: relevance to diabetic nephropathy American Journal of Physiology: Renal Physiology 303 8 2012 F1145 F1150
38. S. Devaraj, P. Tobias, and I. Jialal Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes Cytokine 55 3 2011 441 445
39. R. Gorina, M. Font-Nieves, L. Márquez-Kisinousky, T. Santalucia, and A. Planas Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways Glia 59 2 2011 242 255
40. L. Henning, A. Azad, K. Parsa, J. Crowther, S. Tridandapani, and L. Schlesinger Pulmonary surfactant protein A regulates TLR expression and activity in human macrophages Journal of Immunology 180 12 2008 7847 7858
41. K. Evans, L. Nguyen, J. Chan, B. Innes, J. Bulmer, M. Kilby, and M. Hewison Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells Biology of Reproduction 75 6 2006 816 822
42. M. Gruen, M. Hao, D. Piston, and A. Hasty Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis American Journal of Physiology: Cell Physiology 293 5 2007 C1481 C1488
43. Y. Jia, J. Jing, Y. Bai, Z. Li, L. Liu, J. Luo, M. Liu, and H. Chen Amelioration of experimental autoimmune encephalomyelitis by plumbagin through down-regulation of JAK-STAT and NF-κB signaling pathways PLoS One 6 10 2011 e27006
44. L. Huynh, L. Wang, C. Shi, K. Park-Min, and L. Ivashkiv ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes Journal of Immunology 188 7 2012 3447 3457
45. T. Southworth, A. Metryka, S. Lea, S. Farrow, J. Plumb, and D. Singh IFN-γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation British Journal of Pharmacology 166 7 2012 2070 2083