Infammatory cytokines, adiponectin, insulin resistance and metabolic control after periodontal intervention in patients with type 2 diabetes and chronic periodontitis

Internal Medicine

Volumn 50, Issue 15, 2011, Pages 1569-1574

  Sun, Wei Lian ^a   Chen, Li Li ^a   Zhang, Su Zhan ^a   Wu, Yan Min ^a   Ren, Yue Zhong ^a   Qin, Guang Ming ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Adiponectin; Infammatory cytokines; Insulin resistance; Periodontitis; Type 2 diabetes mellitus

Indexed keywords

ADIPONECTIN; AMPICILLIN; C REACTIVE PROTEIN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TINIDAZOLE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ADIPONECTIN, HUMAN; AUTACOID; CYTOKINE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CELL FUNCTION; CHRONIC PERIODONTITIS; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GINGIVA BLEEDING; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; MOUTH HYGIENE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PREVENTIVE DENTISTRY; TOOTH EXTRACTION; TOOTH PLAQUE; BLOOD; METABOLISM; MIDDLE AGED;

ADIPONECTIN; ADULT; AGED; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CHRONIC PERIODONTITIS; CYTOKINES; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INFLAMMATION MEDIATORS; INSULIN RESISTANCE; LIPIDS; MALE; MIDDLE AGED;

EID: 79961205215     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.50.5166     Document Type: Article

References (30)

1. Yang W, Lu J, Weng J, et al. Prevalence of diabetes among men and women in China. N Engl J Med 362: 1090-1101, 2010.
2. Albandar JM. Epidemiology and risk factors of periodontal diseases. Dent Clin North Am 49: 517-532, 2005.
3. Mealey BL, Rose LF. Diabetes mellitus and inflammatory periodontal diseases. Curr Opin Endocrinol Diabetes Obes 15: 135-141, 2008.
4. Salvi GE, Carollo-Bittel B, Lang NP. Effects of diabetes mellitus on periodontal and peri-implant conditions: update on associations and risks. J Clin Periodontol 35: 398-409, 2008.
5. Genco RJ, Grossi SG, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 76: 2075-2084, 2005.
6. Mealey BL, Rethman MP. Periodontal disease and diabetes mellitus. Bidirectional relationship. Dent Today 22: 107-113, 2003.
7. Taylor GW, Borgnakke WS. Periodontal disease: associations with diabetes, glycemic control and complications. Oral Dis 14: 191-203, 2008.
8. Arner P. Insulin resistance in type 2 diabetes-role of the adi-ponectin. Curr Mol Med 5: 333-339, 2005.
9. Kadowaki T, Yamauchi T, Kubotal N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116: 1784-1792, 2006.
10. Yamaguchi N, Kukita T, Li YJ, et al. Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacil-lus actinomycetemcomitans. FEMS Immunol Med Microbiol 49: 28-34, 2007.
11. Kardesjler L, Buduneli N, Cetinkalp S, Kinane DF. Adipokines and inflammatory mediators after initial periodontal treatment in patients with type 2 diabetes and chronic periodontitis. J Periodontol 81: 24-33, 2010.
12. Darre L, Vergnes JN, Gourdy P, Sixou M. Efficacy of periodontal treatment on glycaemic control in diabetic patients: A metaanalysis of interventional studies. Diabetes Metab 34: 497-506, 2008.
13. Sun WL, Chen LL, Zhang SZ, Ren YZ, Qin GM. Changes of adiponectin and infammatory cytokines after periodontal intervention in type 2 diabetes patients with periodontitis. Arch Oral Biol 55: 970-974, 2010.
14. Jones JA, Miller DR, Wehler CJ, et al. Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study. J Clin Periodontol 34: 46-52, 2007.
15. Lalla E, Kaplan S, Yang J, Roth GA, Papapanou PN, Greenberg S. Effects of periodontal therapy on serum C-reactive protein, sE-selectin and tumor necrosis factor-alpha secretion by peripheral blood-derived macrophages in diabetes. A pilot study. J Periodon-tal Res 42: 274-282, 2007.
16. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985.
17. Ogbera AO. Burden of diabetes mellitus in Nigeria. Trop Doct 37: 153-154, 2007.
18. Tsai C, Hayes C, Taylor GW. Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population. Community Dent Oral Epidemiol 30: 182-192, 2002.
19. Taylor GW. Bidirectional interrelationships between diabetes and periodontal diseases: an epidemiologic perspective. Ann Periodon-tol 6: 99-112, 2001.
20. Hujoel PP, White BA, García RI, Listgarten MA. The dentogingi-val epithelial surface area revisited. J Periodontal Res 36: 48-55, 2001.
21. Loesche WJ, Lopatin DE. Interactions between periodontal disease, medical diseases and immunity in the older individual. Peri-odontol 2000 16: 80-105, 1998.
22. Nishimura F, Soga Y, Iwamoto Y, Kudo C, Murayama Y. Periodontal disease as part of the insulin resistance syndrome in diabetic patients. J Int Acad Periodontol 7: 16-20, 2005.
23. Engebretson S, Chertog R, Nichols A, Hey-Hadavi J, Celenti R, Grbic J. Plasma levels of tumour necrosis factor-alpha in patients with chronic periodontitis and type 2 diabetes. J Clin Periodontol 34: 18-24, 2007.
24. Barnett AH. The importance of treating cardiometabolic risk factors in patients with type 2 diabetes. Diab Vasc Dis Res 5: 9-14, 2008.
25. Inoue M, Maehata E, Yano M, Taniyama M, Suzuki S. Correlation between the adiponectin-leptin ratio and parameters of insulin resistance in patients with type 2 diabetes. Metabolism 54: 281-286, 2005.
26. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest 116: 1793-1801, 2006.
27. Grant PJ. Diabetes mellitus as a prothrombotic condition. J Intern Med 262: 157-172, 2007.
28. Oliveira FJ, Vieira RW, Coelho OR, et al. Systemic inflammation caused by chronic periodontite in patients victims of acute ischemic heart attack. Rev Bras Cir Cardiovasc 25: 51-58, 2010.
29. Ylöstalo P, Anttila S, Rajala U, et al. Periodontal infection and subclinical atherosclerosis: the role of high-density lipoprotein as a modifying factor. J Clin Periodontol 37: 617-624, 2010.
30. Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 321: 405-412, 2000.