The decrease of paclitaxel efflux by pretreatment of interferon-γ and tumor necrosis factor-α after intracerebral microinjection

Brain Research

Volumn 1499, Issue , 2013, Pages 158-162

  Lee, Na Young ^a   Kang, Young Sook ^a  

^a Sookmyung Women's University   (South Korea)

Author keywords

Blood brain barrier; Brain efflux index method; Efflux transport; IFN ; Paclitaxel; TNF

Indexed keywords

GAMMA INTERFERON; INULIN; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; TUMOR NECROSIS FACTOR ALPHA; VERAPAMIL;

ACTIVE TRANSPORT; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EFFLUX INDEX METHOD; CONTROLLED STUDY; DRUG EFFICACY; DRUG ELIMINATION; DRUG TRANSPORT; IN VIVO STUDY; MALE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD-BRAIN BARRIER; INJECTIONS, INTRAVENTRICULAR; INTERFERON-GAMMA; MALE; P-GLYCOPROTEIN; PACLITAXEL; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 84873726083     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.01.005     Document Type: Article

References (26)

1. B. Bauer, A.M. Hartz, and D.S. Miller Tumor necrosis factor α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier Mol. Pharmacol. 71 2007 667 675
2. A.M. Belliard, B. Lacour, R. Farinotti, and C. Leroy Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells J. Pharm. Sci. 93 2004 1524 1536 (15)
3. S.G. Dixit, B. Zingarelli, D.J. Buckley, A.R. Buckley, and G.M. Pauletti Nitric oxide mediates increased P-glycoprotein activity in interferon-{gamma}- stimulated human intestinal cells Am. J. Physiol. Gastrointest. Liver Physiol. 288 2005 G533 G540
4. S. Dohgu, A. Yamauchi, F. Takata, M. Naito, T. Tsuruo, S. Higuchi, Y. Sawada, and Y. Kataoka Transforming growth factor-β1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells Cell. Mol. Neurobiol. 24 2004 491 497
5. S. Fellner, B. Bauer, D.S. Miller, M. Schaffrik, M. Fankhänel, T. Spruss, G. Bernhardt, C. Graeff, L. Färber, H. Gschaidmeier, A. Buschauer, and G. Fricker Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo J Clin Invest 110 2002 1309 1318
6. J. Gligorov, and J.P. Lotz Preclinical pharmacology of the taxanes: implications of the differences Oncologist 9 2 2004 3 8
7. X.R. Hao, D.L. Cao, Y.W. Hu, X.X. Li, X.H. Liu, J. Xiao, D.F. Liao, J. Xiang, and C.K. Tang IFN-gamma down-regulates ABCA1 expression by inhibiting LXRalpha in a JAK/STAT signaling pathway-dependent manner Atherosclerosis 203 2009 417 428
8. A.M. Hartz, B. Bauer, G. Fricker, and D.S. Miller Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-α and lipopolysaccharide Mol. Pharmacol. 69 2006 462 470
9. E. Hedlund, J.A. Gustafsson, and M. Warner Cytochrome P450 in the brain; a review Curr. Drug Metab. 2 2001 245 263
10. J.J. Heimans, J.B. Vermorken, J.G. Wolbers, C.M. Eeltink, O.W. Meijer, M.J. Taphoorn, and J.H. Beijnen Paclitaxel (Taxol) concentrations in brain tumor tissue Ann. Oncol. 5 1994 951 953
11. J.D. Huber, R.D. Egleton, and T.P. Davis Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier Trends Neurosci. 24 2001 719 725
12. M.T. Huizing, V.H. Misser, R.C. Pieters, W.W. ten Bokkel Huinink, C.H. Veenhof, J.B. Vermorken, H.M. Pinedo, and J.H. Beijnen Taxanes: a new class of antitumor agents Cancer Invest. 13 1995 381 404
13. A. Kakee, T. Terasaki, and Y. Sugiyama Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier J. Pharmacol. Exp. Ther. 277 1996 1550 1559
14. C.K. Lee, and J.S. Choi Effects of silibinin, inhibitor of CYP3A4 and P-glycoprotein in vitro, on the pharmacokinetics of paclitaxel after oral and intravenous administration in rats Pharmacology 85 2010 350 356
15. J.W. Lee, Y.J. Choi, S.I. Kim, S.Y. Lee, S.S. Kang, N.H. Kim, Y.S. Kwon, H.J. Lee, W. Chun, and S.S. Kim Betulinic Acid Inhibits LPS-Induced MMP-9 Expression by Suppressing NF-kB Activation in BV2 Microglial Cells Biomol. Ther. 19 2011 431 437
16. N.Y. Lee, P. Rieckmann, and Y.S. Kang The changes of P-glycoprotein activity by interferon-γ and tumor necrosis factor-α in primary and immortalized human brain microvascular endothelial cells Biomol. Ther. 20 2012 293 298
17. D.S. Miller Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier Trends Pharmacol. Sci. 31 2010 246 254
18. S. Mori, S. Ohtsuki, H. Takanaga, T. Kikkawa, Y.S. Kang, and T. Terasaki Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs J. Neurochem. 90 2004 931 941
19. M.D. Prados, S.C. Schold, A.M. Spence, M.S. Berger, L.D. McAllister, M.P. Mehta, M.R. Gilbert, D. Fulton, J. Kuhn, K. Lamborn, D.J. Rector, and S.M. Chang Phase II study of paclitaxel in patients with recurrent malignant glioma J. Clin. Oncol. 14 1996 2316 2321
20. P. Puddu, S. Fais, F. Luciani, G. Gherardi, M.L. Dupuis, G. Romagnoli, C. Ramoni, M. Cianfriglia, and S. Gessani Interferon-gamma up-regulates expression and activity of P-glycoprotein in human peripheral blood monocyte-derived macrophages Lab. Invest. 79 1999 1299 1309
21. M. Rizzi, S. Caccia, G. Guiso, C. Richichi, J.A. Gorter, E. Aronica, M. Aliprandi, R. Bagnati, R. Fanelli, M. D'Incalci, R. Samanin, and A. Vezzani Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance J. Neurosci. 22 2002 5833 5839
22. A.H. Schinkel, J.J.M. Smit, O. van Tellingen, J.H. Beijnen, E. Wagenaar, L. van Deemter, C.A.A.M. Mol, M.A. van der Valk, E.C. Robanus-Maandag, H.P.J. te Riele, A.J.M. Berns, and P. Borst Distribution of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Cell 77 1994 491 502
23. A. Sparreboom, J. van Asperen, U. Mayer, A.H. Schinkel, J.W. Smit, D.K. Meijer, P. Borst, W.J. Nooijen, J.H. Beijnen, and O. van Tellingen Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine Proc. Natl. Acad. Sci. U.S.A. 94 1997 2031 2035
24. D. Théron, S. Barraud de Lagerie, S. Tardivel, H. Pelerin, P. Demeuse, C. Mercier, A. Mabondzo, R. Farinotti, B. Lacour, F. Roux, and F. Gimenez Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT Biochem. Pharmacol. 66 2003 579 587 (19)
25. R. Vaclavikova, P. Soucek, L. Svobodova, P. Anzenbacher, P. Simek, F.P. Guengerich, and I. Gut Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Drug Metab. Dispos. 32 2004 666 674
26. W. Walther, and U. Stein Influence of cytokines on mdr1 expression in human colon carcinoma cell lines: increased cytotoxicity of MDR relevant drugs. J. Cancer Res. Clin. Oncol. 120 1994 471 478