Effect of tumor necrosis factor-α and interferon-γ on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells

Journal of Pharmaceutical Sciences

Volumn 93, Issue 6, 2004, Pages 1524-1536

  Belliard, Anne Marie ^a   Lacour, Bernard ^a,b   Farinotti, Robert ^a   Leroy, Christine ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

ABC transporters; Caco 2 cells; Confocal laser scanning microscopy; Cytokine; Drug transport; Inflammation; Intestinal secretion transport; MDR1; P glycoprotein; Semiquantitative reverse transcription polymerase chain reaction (RT PCR)

Indexed keywords

ABC TRANSPORTER; GAMMA INTERFERON; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; RHODAMINE 123; TUMOR NECROSIS FACTOR ALPHA; XENOBIOTIC AGENT;

ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL STRAIN CACO 2; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG TRANSPORT; ENTERITIS; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 2642537787     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20072     Document Type: Article

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