Phase II study of paclitaxel in patients with recurrent malignant glioma

Journal of Clinical Oncology

Volumn 14, Issue 8, 1996, Pages 2316-2521

  Prados, M D ^a   Schold, S C ^a   Spence, A M ^a   Berger, M S ^a   McAllister, L D ^a   Mehta, M P ^a   Gilbert, M R ^a   Fulton, D ^a   Kuhn, J ^a   Lamborn, K ^a   Rector, D J ^a   Chang, S M ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; DIPHENHYDRAMINE; GRANULOCYTE COLONY STIMULATING FACTOR; PACLITAXEL; RANITIDINE;

ADOLESCENT; ADULT; AGED; ALOPECIA; ARTHRALGIA; ARTICLE; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER RADIOTHERAPY; CARDIOTOXICITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GLIOBLASTOMA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; NAUSEA; NEUROTOXICITY; ORAL DRUG ADMINISTRATION; PERIPHERAL NEUROPATHY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RECURRENT CANCER; TREATMENT OUTCOME;

EID: 9444291844     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1996.14.8.2316     Document Type: Article

References (23)

1. Rowinsky EK, Cazenave LA, Donehower RC: Paclitaxel: A novel investigational antimicrotubule agent. J Natl Cancer Inst 82:1247-1259, 1990
2. McGuire WP, Rowinsky EK, Rosenhein NB, et al: Paclitaxel: A unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann Intern Med 111:273-279, 1989
3. Holmes FA, Walters RS, Theriault RL, et al: Phase II trial of paclitaxel, an active drug in the treatment of metastatic breast cancer. J Natl Cancer Inst 83:1797-1805, 1991
4. Rowinsky EK, Donehower RC: Paclitaxel (Taxol). N Engl J Med 15:1004-1014, 1995
5. Horwitz SB: Paclitaxel: Mechanisms of action. Ann Oncol 5:S3-6, 1994 (suppl 6)
6. Younes A, Sards A, Melnyk A, et al: Three-hour paclitaxel infusion in patients with refractory and relapsed non-Hodgkin's lymphoma. J Clin Oncol 13:583-587, 1995
7. Rowinsky EK, Burke PJ, Karp JE, et al: Phase I and pharmacodynamic study of paclitaxel in refractory acute leukemias. Cancer Res 49:4640-4647, 1989
8. Roth BJ: Preliminary experience with paclitaxel in advanced bladder cancer. Semin Oncol 22:1-5, 1995 (suppl 6)
9. Ajani JA, Ilson DH, Daugherty K, et al: Paclitaxel in the treatment of carcinoma of the esophagus. Semin Oncol 22:35-40, 1995 (suppl 6)
10. Smith RE, Thornton DE, Allen J: A phase II trial of paclitaxel in squamous cell carcinoma of the head and neck with correlative laboratory studies. Semin Oncol 22:41-46, 1995 (suppl 6)
11. Buzdar AU, Holmes FA, Hortobagyi GN: Paclitaxel in the treatment of metastatic breast cancer: M.D. Anderson Cancer Center experience. Semin Oncol 22:101-104, 1995 (suppl 6)
12. Wilson WH, Chabner BA, Bryant G, et al: Phase II study of paclitaxel in relapsed non-Hodgkin's lymphomas. J Clin Oncol 13:381-386, 1995
13. Schiller JH, Storer B, Tutsch K, et al: Phase I trial of 3-hour infusion of paclitaxel with or without granulocyte colony-stimulating factor in patients with advanced cancer. J Clin Oncol 12:241-248, 1994
14. 3H-Taxol in the rat. Proc Am Assoc Cancer Res 34:381, 1993 (abstr)
15. Cahan MA, Walter KA, Colvin OM, et al: The cytotoxicity of paclitaxel in vitro against human and rat malignant brain tumors. Cancer Chemother Pharmacol 33:441-4, 1994
16. Riondel J, Jacrot M, Fessi M, et al: Effects of free and liposome-encapsulated paclitaxel on two brain tumors xenografted into nude mice. In Vivo 6:23-27, 1992
17. Riondel J, Jacrot M, Picot F, et al: Therapeutic response to paclitaxel of six human tumors xenografted into nude mice. Cancer Chemother Pharmacol 17:137-142, 1986
18. Chamberlain MC, Kormanik P: Salvage chemotherapy with paclitaxel for recurrent primary brain tumors. J Clin Oncol 13:2066-2071, 1995
19. Rowinsky EK, Wright M, Monsarrat B, et al: Clinical pharmacology and metabolism of paclitaxel: Update 1993. Ann Oncol 5:S7-S16, 1994 (suppl 6)
20. 3H-paclitaxel (3H-P) tissue concentrations within intracranial malignant gliomas and normal rat brains after intravenous administration. Proc Am Soc Clin Oncol 14:149, 1995 (abstr 292)
21. Heimans JJ, Vermorken JB, Wolbers JG, et al: Paclitaxel concentrations in brain tumor tissue. Ann Oncol 5:951-953, 1994
22. Cresteil T, Monsarrat B, Alvinerie P, et al: Taxol metabolism by human liver microsomes: Identification of cytochrome P450 isozymes involved in its biotransformation. Cancer Res 54:386-392, 1994
23. Huizing MT, Vermorken JB, Rosing WW, et al: Pharmacology of paclitaxel and three main metabolites in patients with advanced breast cancer refractory to anthracycline therapy treated with a 3-hour paclitaxel infusion: A European Cancer Center (ECC) trial. Proc Am Soc Clin Oncol 14:460, 1995 (abstr 1482)