ADP-induced platelet aggregation after addition of tramadol in vitro in fed and fasted horses plasma

Research in Veterinary Science

Volumn 94, Issue 2, 2013, Pages 325-330

  Casella, S ^a   Giannetto, C ^a   Giudice, E ^a   Marafioti, S ^a   Fazio, F ^a   Assenza, A ^a   Piccione, G ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

Adenosine diphosphate; Fasting; Feeding; Horse; Platelet aggregation; Tramadol

Indexed keywords

ADENOSINE DIPHOSPHATE; TRAMADOL;

ANIMAL EXPERIMENT; ANIMAL FOOD; ARTICLE; BLOOD CLOTTING; BLOOD SAMPLING; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG MECHANISM; FEMALE; HORSE; IN VITRO STUDY; MALE; MULTIVARIATE ANALYSIS OF VARIANCE; NONHUMAN; THROMBOCYTE AGGREGATION; THROMBOCYTE DYSFUNCTION; THROMBOCYTE FUNCTION; VETERINARY MEDICINE;

ADENOSINE DIPHOSPHATE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD DEPRIVATION; HORSES; MALE; PLASMA; PLATELET AGGREGATION; TRAMADOL;

ANIMALIA; EQUIDAE;

EID: 84873718066     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2012.09.005     Document Type: Article

References (58)

1. Akopov S.E., Gabrielian E.S. Effects of aspirin, dipyridamole, nifedipine and cavinton which act on platelet aggregation induced y different aggregating agents alone and in combination. European Journal of Clinical Pharmacology 1992, 42:257-259.
2. Antila H., Manner T., Kuurila K., Salanterä S., Kujala R., Aantaa R. Ketoprofen and tramadol for analgesia during early recovery after tonsillectomy in children. Pediatric Anesthesia 2006, 16:548-553.
3. Berrocoso E., Rojas-Corrales M.O., Mico J.A. Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice. Psychopharmacology 2006, 188:111-118.
4. Britzi M., Gross M., Lavy E., Soback S., Steinman A. Bioavailability and pharmacokinetics of metronidazole in fed and fasted horses. Journal of Veterinary Pharmacology and Therapeutics 2010, 33:511-514.
5. Brondani J.T., Luna S.P.L., Marcello G.C.G., Padovani C.R. Perioperative administration of vedaprofen, tramadol or their combination does not interfere with platelet aggregation, bleeding time and biochemical variables in cats. Journal of Feline Medicine Surgery 2009, 11:503-509.
6. Cambridge H., Lees P., Hooke R.E., Russell C.S. Antithrombotic actions of aspirin in the horse. Equine Veterinary Journal 1991, 23:123-127.
7. Casella S., Giudice E., Alberghina D., Giannetto C., Marafioti S., Piccione G. Hydrocortisone inhibition of adenosine diphospate (ADP)-induced platelet aggregation in horse. Comparative Clinical Pathology 2010, 10.1007/s00580-010-0997-2.
8. Clemmons R.M., Meyers K.M. Acquisition and aggregation of canine blood platelets: basic mechanisms of function and differences because of breed origin. American Journal of Veterinary Research 1984, 45:137-144.
9. Cox S., Villarino N., Doherty T. Determination of oral tramadol pharmacokinetics in horses. Research in Veterinary Science 2010, 10.1016/j.rvsc.2010.02.011.
10. De Leo M., Giorgi M., Saccomani G., Manera C., Branca A. Evaluation of tramadol and its main metabolites in horse plasma by high-performance liquid chromatography/fluorescence and liquid chromatography/electrospray ionization tandem mass spectrometry techniques. Rapid Communications in Mass Spectrometry: RCM 2009, 23:228-236.
11. Desmeules J., Piguet V., Collart L., Dayer P. Contribution of monoaminergic modulation to the analgesics effect of tramadol. British Journal of Pharmacology 1996, 41:7-12.
12. Dordoni P.L., Frassanito L., Bruno M.F., Proietti R., De Cristofaro R., Ciabattoni G., Ardito G., Crocchiolo R., Landolfi R., Rocca B. In vivo and in vitro effects of different anaesthetics on platelet function. British Journal of Haematology 2004, 125:79-82.
13. Elghazali M., Barezaik I.M., Abdel Hadi A.A., Eltaybed F.M., Al Masri J., Wasfi I.A. The pharmacokinetics, metabolism and urinary detection time of tramadol in camels. Veterinary Journal 2007, 178:272-277.
14. Gader A.M.A., Ghumlas A.K., Hussai M.F., Haidary A.I. Platelet aggregation and platelet function analyzer 100 (PFA-100) closure time in camels - a comparative study with humans. Comparative Clinical Pathology 2006, 15:31-37.
15. Gilbert R.M., Burd K.E., Kutzler M.A. Platelet aggregation responses in clinically healthy adult Ilams. Veterinary Clinical Pathology 2009, 38:42-45.
16. Giorgi M., Saccomani G., Daniello M.R., Manera C., Soldani G., Ferrarini P.L., Giusani M. In vitro metabolism of tramadol in horses: preliminary data. Drug Metabolism Drug Metabolite Enzyme 2006, 29:124.
17. Giorgi M., Soldani G., Manera C., Ferrarini P., Sgorbini M., Saccomanni G. Pharmakinetics of tramadol and its metabolites M1, M2 and M5 in horses following intravenous, immediate release (fasted/fed) and sustained release single dose administration. Journal Equine of Veterinary Science 2007, 27:481-488.
18. Giorgi M., Saccomani G., Lebkowska-Wieruszewska B., Kowalski C. Pharmacokinetic evaluation of tramadol and its major metabolites after single oral sustained tablet administration in the dog: a pilot study. Veterinary Journal 2009, 180:253-255.
19. Heath M.F., Evans R.J., Poole A.W., Hayes L.J., McEvoy R.T., Litter R.M. The effects of aspirin and paracetamol on the aggregation of equine blood platelets. Journal of Veterinary Pharmacology and Therapeutics 2008, 17:374-378.
20. Ide S., Minami M., Ishihara K., Uhl G.R., Sora I., Ikeda K. Mu opioid receptor-dependent and independent components in effects of tramadol. Neuropharmacology 2006, 51:651-658.
21. 2-adrenergic constriction in the canine epicardial coronary microcirculation. Circulation 1993, 87:1264-1274.
22. Kelly A.B., Steffey E.P., McNeal D., Willits N. Immediate and long-term effects of halothane anesthesia on equine platelet function. Journal of Veterinary Pharmacology and Therapeutics 2008, 8:284-289.
23. Kowalski K.A., McConnel L.A., Sadoff D.A., Wes Leid R. Modulation of equine platelet function by diethylcarbamazine (DEC). American Association of Pathology 1983, 113:1-7.
24. Kozek-Langenecker S.A. The effects of drugs used in anaesthesia on platelet membrane receptors and on platelet function. Medical Chemistry Reviews 2004, 10:101-110.
25. Kucuk A., Kadioglu Y., Celebi F. Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography-diode array detector method using liquid-liquid extraction. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2005, 816:203-208.
26. Kukanich B., Papich M.G. Pharmacokinetics of tramadol and the metabolite O-desmethyltramadol in dogs. Journal of Veterinary Pharmacology and Therapeutics 2004, 27:239-246.
27. Lindahl T.L., Ramström S. Methods for evaluation of platelet function. Transfusion and Apheresis Science 2009, 41:121-125.
28. McMillan C.J., Livingston A., Clark C.R., Dowling P.M., Taylor S.M., Duke T., Terlinden R. Pharmacokinetics of intravenous tramadol in dogs. Canadian Journal of Veterinary Research 2008, 72:325-331.
29. Meyers K.M., Lindner C., Kats J., Grant B. Phenylbutazone inhibition of equine platelet function. American Journal of Veterinary Research 1979, 40:265-270.
30. Monreal L., Anglés A., Espada Y., Monasteiro J., Monreal M. Hypercoagulation and hypofibrinolysis in horses with colic and DIC. Equine Veterinary Journal. Supplement 2000, 32:19-25.
31. Natalini C., Robinson E. Evaluation of the analgesic effects of epidurally administered morphine, alfentanil, butorphanol, tramadol, and U50488H in horses. American Journal of Veterinary Research 2000, 61:1579-1586.
32. Pelagalli A., Lombardi P., d'Angelo D., Della Morte R., Avallone L., Staiano N. Species variability in platelet aggregation response to different agonists. The Journal of Comparative Pathology 2002, 127:126-132.
33. Piccione G., Casella S., Giannetto C., Assenza A., Caola G. Effect of different storage conditions on platelet aggregation in horse. Journal Equine of Veterinary Science 2010, 30:371-375.
34. Porreca F., Ossipov M.H., Gebhart G.F. Chronic pain and medullary descending facilitation. Trends in Neurosciences 2002, 25:319-325.
35. Pypendop B.H., Ilkiw J.E. Pharmacokinetics of tramadol, and its metabolite O-desmethyl-tramadol, in cats. The Journal of Veterinary Pharmacology and Therapeutics 2007, 31:52-59.
36. Raffa R.B. Basic pharmacology relevant to drug abuse assessment: tramadol as example. Journal of Clinical Pharmacology and Therapeutics 2008, 33:101-108.
37. Raffa R., Friderichs E., Reimann W., Shank R., Codd E., Vaught J. Opioid ana nonopioid components independently contribute to the mechanism of action of tramadol, an " atypical" opioid analgesix. Journal of Pharmacology and Experimental Therapeutics 1992, 260:275-285.
38. Raffa R.B., Nayak R.K., Liao S., Minn F.L. The mechanism of action and pharmacokinetics of tramadol hydrochloride. Reviews in Contemporary Pharmacology 1995, 6:485-498.
39. Rickards K.J., Andrews M.J., Waterworth T.H., Alexander G.B.C., Cunningham F.M. Differential effects of phosphodiesterase inhibitors on platelet activating factor (PAF)- and adenosine diphosphate (ADP)-induced equine platelet aggregation. Journal of Veterinary Pharmacology and Therapeutics 2003, 26:277-282.
40. Ruggeri Z.M. Mechanisms initiating platelet thrombus formation. Thrombosis and Haemostasis 1997, 78:611-616.
41. Schmidt L.E., Dalhoff K. Food-drug interactions. Drugs 2002, 62:1481-1502.
42. Schuerholz T., Keil O., Wagner T., Klinzing S., Sümpelmann R., Oberle V., Marx G. Hydrocortisone does not affect major platelet receptors in inflammation in vitro. Steroids 2007, 72:609-613.
43. Scott L.J., Perry C.M. Tramadol: a review of its use in perioperative pain. Drugs 2000, 60:139-176.
44. Sergeev P.V., Dukhanin A.S., Gubaeva F.R. Early stages in the mechanism of action of glucocorticoids on human platelets. Effect of hydrocortisone on platelet aggregation. Bulletin of Experimental Biology and Medicine 1997, 123:54-57.
45. Shilo Y., Britzi M., Eytan B., Lifschtz T., Soback S., Steinman A. Pharmacokinetics of tramadol in horses after intravenous, intramuscular and oral administration. Journal of Veterinary Pharmacology and Therapeutics 2008, 31:60-65.
46. Soloview M.V., Okazaki Y., Harasaki H. Whole blood platelet aggregation in humans and animals: a comparative study. Journal of Surgical Research 1999, 82:180-187.
47. Souza M.J., Greenacre C.B., Cox S.K. Pharmacokinetics of orally administered tramadol in domestic rabbits (Oryctolagus cuniculus). American Journal of Veterinary Research 2008, 69:979-982.
48. Suzuki R., Rygh L.J., Dickenson A.H. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends in Pharmacological Sciences 2004, 25:613-617.
49. Tao Q., Stoen D.J., Borenstein M.R., Codd E.E., Coogan T.P., Desai-Krieger D., Liao S., Raffa R.B. Differential tramadol and O-desmethyl metabolite levels in brain vs. plasma of mice and rats administered tramadol hydrochloride orally. Journal of Clinically Pharmacy and Therapeutics 2002, 27:99-106.
50. Thomas J.S. Comparison of platelet aggregation and adenosine triphosphate secretion in whole blood and platelet-rich plasma from normal dogs. Comparative Haematology International 1996, 6:70-76.
51. Thrall M.A., Baker D.C., Campbell T.W., DeNicola D., Fettman M.J., Lassen E.D., Rebar A., Weiser G. Veterinary Hematology and Clinical Chemistry 2004, Lippincott Williams & Wilkins.
52. Tirelli A., Guastafierro S., Annunziata S., Guariglia R., Coppola L. Effects of β-endorphin and met-enkephalin on platelet activity. American Journal of Hematology 2001, 6:1-3.
53. Vettorato E., Zonca A., Isola M., Villa R., Gallo M., Ravasio G., Beccaglia M., Montesissa C., Cagnardi P. Pharmacokinetics and efficacy of intravenous and extradural tramadol in dogs. Veterinary Journal 2010, 183:310-315.
54. Vullo, C., Catone, G., Laus, F., Scrollavezza, P., 2006. Efficacia analgesica del tramadolo nella sedazione del cavallo. In: Società Italiana Veterinari per Equini. XII SIVE Congress, Bologna, Italy.
55. Vuong C., Van Uum S.H.M., O'Dell L.E., Lutfy K., Friedman T.C. The effects of opioids and opioid analogs on animal and human endocrine systems. Endocrine Reviews 2010, 31:98-132.
56. Wu N.M., McKown N.A., Gauthier A.D., Jones W.J., Raffa R.B. Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog. Xenobiotica 2001, 31:423-441.
57. Wu W.N., McKown N.A., Codd E.E., Raffa R.B. Metabolism of two analgesic agents, tramadol-n-oxide and tramadol, in specific pathogen-free and axenic mice. Xenobiotica: The Fate of Foreign Compounds in Biological Systems 2006, 36:551-565.
58. Zaho Y., Tao T., Wu J., Pi J., He N., Chai X., Chen Q. Pharmacokinetics of tramadol in rat plasma and cerebrospinal fluid after intranasal administration. The Journal of Pharmacy and Pharmacology 2008, 60:1149-1154.