-
1
-
-
0027194499
-
Tramadol: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states
-
Lee C.R., McTavish D., and Sorkin E.M. Tramadol: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 46 (1993) 313-340
-
(1993)
Drugs
, vol.46
, pp. 313-340
-
-
Lee, C.R.1
McTavish, D.2
Sorkin, E.M.3
-
3
-
-
0030033533
-
Contribution of monoaminergic modulation to the analgesic effect of tramadol
-
Desmeules J.A., Piguet V., Collart L., and Dayer P. Contribution of monoaminergic modulation to the analgesic effect of tramadol. Br J Clin Pharmacol 41 (1996) 7-12
-
(1996)
Br J Clin Pharmacol
, vol.41
, pp. 7-12
-
-
Desmeules, J.A.1
Piguet, V.2
Collart, L.3
Dayer, P.4
-
4
-
-
33747047219
-
Mu opioid receptor-dependent and independent components in effects of tramadol
-
Ide S., Minami M., Ishihara K., Uhl G.R., Sora I., and Ikeda K. Mu opioid receptor-dependent and independent components in effects of tramadol. Neuropharmacology 51 (2006) 651-658
-
(2006)
Neuropharmacology
, vol.51
, pp. 651-658
-
-
Ide, S.1
Minami, M.2
Ishihara, K.3
Uhl, G.R.4
Sora, I.5
Ikeda, K.6
-
5
-
-
0037248361
-
Adding ketoprofen to intravenous patient-controlled analgesia with tramadol after major gynecological cancer surgery: a double-blinded, randomized, placebo-controlled clinical trial
-
Tuncer S., Pirbudak L., Balat O., and Capar M. Adding ketoprofen to intravenous patient-controlled analgesia with tramadol after major gynecological cancer surgery: a double-blinded, randomized, placebo-controlled clinical trial. Eur J Gynaecol Oncol 24 (2003) 181-184
-
(2003)
Eur J Gynaecol Oncol
, vol.24
, pp. 181-184
-
-
Tuncer, S.1
Pirbudak, L.2
Balat, O.3
Capar, M.4
-
6
-
-
13544270927
-
Tramadol: does it have a role in emergency medicine?
-
Close B.R. Tramadol: does it have a role in emergency medicine?. Emerg Med Australas 17 (2005) 73-83
-
(2005)
Emerg Med Australas
, vol.17
, pp. 73-83
-
-
Close, B.R.1
-
7
-
-
0034201526
-
A prospective, open, single blind, randomized study comparing four analgesics in the treatment of peripheral injury in the emergency department
-
Hoogewijs J., Diltoer M.W., Hubloue I., Spapen H.D., Camu F., Corne L., et al. A prospective, open, single blind, randomized study comparing four analgesics in the treatment of peripheral injury in the emergency department. Eur J Emerg Med 7 (2000) 119-123
-
(2000)
Eur J Emerg Med
, vol.7
, pp. 119-123
-
-
Hoogewijs, J.1
Diltoer, M.W.2
Hubloue, I.3
Spapen, H.D.4
Camu, F.5
Corne, L.6
-
8
-
-
0031950478
-
Tramadol versus hydrocodone-acetaminophen in acute musculoskeletal pain: a randomized, double-blind clinical trial
-
Turturro M.A., Paris P.M., and Larkin G.L. Tramadol versus hydrocodone-acetaminophen in acute musculoskeletal pain: a randomized, double-blind clinical trial. Ann Emerg Med 32 (1998) 139-143
-
(1998)
Ann Emerg Med
, vol.32
, pp. 139-143
-
-
Turturro, M.A.1
Paris, P.M.2
Larkin, G.L.3
-
9
-
-
0036276786
-
Metabolism of the analgesic drug ULTRAM (tramadol hydrochloride) in humans: API-MS and MS/MS characterization of metabolites
-
Wu W.N., McKown L.A., and Liao S. Metabolism of the analgesic drug ULTRAM (tramadol hydrochloride) in humans: API-MS and MS/MS characterization of metabolites. Xenobiotica 32 (2002) 411-425
-
(2002)
Xenobiotica
, vol.32
, pp. 411-425
-
-
Wu, W.N.1
McKown, L.A.2
Liao, S.3
-
11
-
-
0034946742
-
Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes
-
Subrahmanyam V., Renwick A.B., Young P.J., Price R.J., Tonelli A.P., and Lake B.G. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes. Drug Metab Dispos 29 (2001) 1146-1155
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1146-1155
-
-
Subrahmanyam, V.1
Renwick, A.B.2
Young, P.J.3
Price, R.J.4
Tonelli, A.P.5
Lake, B.G.6
-
12
-
-
0026512239
-
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic
-
Raffa R.B., Friderichs E., Reimann W., Shank R.P., Codd E.E., and Vaught J.L. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther 260 (1992) 275-285
-
(1992)
J Pharmacol Exp Ther
, vol.260
, pp. 275-285
-
-
Raffa, R.B.1
Friderichs, E.2
Reimann, W.3
Shank, R.P.4
Codd, E.E.5
Vaught, J.L.6
-
13
-
-
36248933640
-
-
Kogel B, Englberger W, Hennies HH, Friderichs E. Involvement of metabolites in the analgesic action of tramadol. Proceedings 9th World Congress of Pain; 1999:523.
-
-
-
-
14
-
-
0033901486
-
Affinity, potency and efficacy of tramadol and its metabolites at the cloned human mu-opioid receptor
-
Gillen C., Haurand M., Kobelt D.J., and Wnendt S. Affinity, potency and efficacy of tramadol and its metabolites at the cloned human mu-opioid receptor. Naunyn Schmiedeberg Arch Pharmacol 362 (2000) 116-121
-
(2000)
Naunyn Schmiedeberg Arch Pharmacol
, vol.362
, pp. 116-121
-
-
Gillen, C.1
Haurand, M.2
Kobelt, D.J.3
Wnendt, S.4
-
15
-
-
0033808357
-
Modeling of the in vivo antinociceptive interaction between an opioid agonist, (+)-O-desmethyltramadol, and a monoamine reuptake inhibitor, (-)-O-desmethyltramadol, in rats
-
Garrido M.J., Valle M., Campanero M.A., Calvo R., and Troconiz I.F. Modeling of the in vivo antinociceptive interaction between an opioid agonist, (+)-O-desmethyltramadol, and a monoamine reuptake inhibitor, (-)-O-desmethyltramadol, in rats. J Pharmacol Exp Ther 295 (2000) 352-359
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 352-359
-
-
Garrido, M.J.1
Valle, M.2
Campanero, M.A.3
Calvo, R.4
Troconiz, I.F.5
-
16
-
-
0037405133
-
Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity
-
Garrido M.J., Sayar O., Segura C., Rapado J., Dios-Vieitez M.C., Renedo M.J., et al. Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity. J Pharmacol Exp Ther 305 (2003) 710-718
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 710-718
-
-
Garrido, M.J.1
Sayar, O.2
Segura, C.3
Rapado, J.4
Dios-Vieitez, M.C.5
Renedo, M.J.6
-
18
-
-
4344658830
-
Pharmacokinetics of tramadol and the metabolite O-desmethyltramadol in dogs
-
KuKanich B., and Papich M.G. Pharmacokinetics of tramadol and the metabolite O-desmethyltramadol in dogs. J Vet Pharmacol Ther 27 (2004) 239-246
-
(2004)
J Vet Pharmacol Ther
, vol.27
, pp. 239-246
-
-
KuKanich, B.1
Papich, M.G.2
-
19
-
-
0031460240
-
Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol
-
Paar W.D., Poche S., Gerloff J., and Dengler H.J. Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol. Eur J Clin Pharmacol 53 (1997) 235-239
-
(1997)
Eur J Clin Pharmacol
, vol.53
, pp. 235-239
-
-
Paar, W.D.1
Poche, S.2
Gerloff, J.3
Dengler, H.J.4
-
20
-
-
0033893537
-
Tramadol: a review of its use in perioperative pain
-
Scott L.J., and Perry C.M. Tramadol: a review of its use in perioperative pain. Drugs 60 (2000) 139-176
-
(2000)
Drugs
, vol.60
, pp. 139-176
-
-
Scott, L.J.1
Perry, C.M.2
-
21
-
-
0035691828
-
Oxidative monensin metabolism and cytochrome P450 3A content and functions in liver microsomes from horses, pigs, broiler chicks, cattle and rats
-
Nebbia C., Ceppa L., Dacasto M., Nachtmann C., and Carletti M. Oxidative monensin metabolism and cytochrome P450 3A content and functions in liver microsomes from horses, pigs, broiler chicks, cattle and rats. J Vet Pharmacol Ther 24 (2003) 399-403
-
(2003)
J Vet Pharmacol Ther
, vol.24
, pp. 399-403
-
-
Nebbia, C.1
Ceppa, L.2
Dacasto, M.3
Nachtmann, C.4
Carletti, M.5
-
22
-
-
36249020313
-
In vitro metabolism of tramadol in horses: preliminary data
-
Giorgi M., Saccomanni G., Daniello M.R., Manera C., Soldani G., Ferrarini P.L., et al. In vitro metabolism of tramadol in horses: preliminary data. J Vet Pharmacol Ther 26 (2006) 124
-
(2006)
J Vet Pharmacol Ther
, vol.26
, pp. 124
-
-
Giorgi, M.1
Saccomanni, G.2
Daniello, M.R.3
Manera, C.4
Soldani, G.5
Ferrarini, P.L.6
-
23
-
-
0034885572
-
Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog
-
Wu W.N., McKown L.A., Gauthier A.D., Jones W.J., and Raffa R.B. Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog. Xenobiotica 31 (2001) 423-441
-
(2001)
Xenobiotica
, vol.31
, pp. 423-441
-
-
Wu, W.N.1
McKown, L.A.2
Gauthier, A.D.3
Jones, W.J.4
Raffa, R.B.5
-
24
-
-
30444449964
-
Development and validation of a rapid HPLC method for simultaneous determination of tramadol, and its two main metabolites in human plasma
-
Rouini M.R., Ardakani Y.H., Soltani F., Aboul-Enein H.Y., and Foroumadi A. Development and validation of a rapid HPLC method for simultaneous determination of tramadol, and its two main metabolites in human plasma. J Chromatogr B 830 (2006) 207-211
-
(2006)
J Chromatogr B
, vol.830
, pp. 207-211
-
-
Rouini, M.R.1
Ardakani, Y.H.2
Soltani, F.3
Aboul-Enein, H.Y.4
Foroumadi, A.5
-
25
-
-
0032804758
-
Pharmacokinetic properties of tramadol sustained release capsules. 2nd communication: investigation of relative bioavailability and food interaction
-
Raber M., Schulz H.U., Schurer M., Bias-Imhoff U., and Momberger H. Pharmacokinetic properties of tramadol sustained release capsules. 2nd communication: investigation of relative bioavailability and food interaction. Arzneim Forsch Drug Res 49 (1999) 588-593
-
(1999)
Arzneim Forsch Drug Res
, vol.49
, pp. 588-593
-
-
Raber, M.1
Schulz, H.U.2
Schurer, M.3
Bias-Imhoff, U.4
Momberger, H.5
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