Investigation of the pharmacokinetics and determination of tramadol in rabbit plasma by a high-performance liquid chromatography-diode array detector method using liquid-liquid extraction

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 816, Issue 1-2, 2005, Pages 203-208

  Küçük, Aysel ^a   Kadioǧlu, Yücel ^a   Çelebi, Fikret ^a  

^a ATATÜRK UNIVERSITY   (Turkey)

Author keywords

HPLC; Pharmacokinetics; Tramadol

Indexed keywords

ARRAYS; CONCENTRATION (PROCESS); DIODES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLVENT EXTRACTION;

DIODE ARRAY DETECTOR (DAD); LIQUID-LIQUID EXTRACTION; RABIT PLASMA; TRAMADOL;

PHARMACOKINETICS;

ACETIC ACID ETHYL ESTER; TRAMADOL;

ACCURACY; ANIMAL EXPERIMENT; ANTENNA; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIODE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG INFUSION; DRUG SENSITIVITY; DRUG SPECIFICITY; INJECTION; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

ANALGESICS, OPIOID; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; INJECTIONS, INTRAVENOUS; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRAMADOL;

ORYCTOLAGUS CUNICULUS;

EID: 12444306493     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.11.031     Document Type: Article

References (21)

1. R.B. Raffa, E. Friderichs, W. Reimann, R.P. Shank, E.E. Codd, and J.L. Vaught J. Pharmacol. Exp. Ther. 260 1992 275
2. K.S. Lewis, and N.H. Han Am. J. Health-System Pharm. 54 1997 643
3. G.C. Yeh, M.T. Sheu, C.L. Yen, Y.W. Wang, C.H. Liu, and H.O. Ho J. Chromatogr. B 723 1999 247
4. I.Y. Zaghloul, and M.A. Radwan J. Liq. Chromatogr. Relat. Technol. 20 1997 779
5. S.H. Gan, and R. Ismail J. Chromatogr. B 759 2001 325
6. S.H. Gan, R. Ismail, W.A. Wan Adnan, Z. Wan, and Method Development J. Chromatogr. B 772 2002 123
7. A. Ceccato, P. Chiap, Ph. Hubert, and J. Crommen J. Chromatogr. B 698 1997 161
8. B. Elsing, and G. Blaschke J. Chromatogr. 612 1993 223
9. M. Nobilis, J. Pastera, P. Anzenbacher, D. Svoboda, J. Kopecky, and F. Perlik J. Chromatogr. B 681 1996 177
10. P. Overbeck, and G. Blaschke J. Chromatogr. B 732 1999 185
11. M. Valle, J.M. Pavon, R. Calvo, M.A. Campanero, and I.F. Troconiz J. Chromatogr. B 724 1999 83
12. R. Becker, and W. Lintz J. Chromatogr. 377 1986 213
13. W. Lintz, and H. Uragg J. Chromatogr. 341 1985 65
14. W. Lintz, S. Erlaçin, E. Frankus, and H. Uragg Arzneimittelforschung/Drug Res. 31 1981 1932
15. U.B. Soetebeer, M.O. Schierenberg, H. Schulz, G. Grünefeld, P. Andresen, and G. Blaschke J. Chromatogr. B 745 2000 271
16. S. Rudaz, S. Cherkaoui, P. Dayer, S. Fanali, and J.L. Veuthey J. Chromatogr. A 868 2000 295
17. H.E. Abdellatef J. Pharm. Biomed. Anal. 29 2002 835
18. S.T. Ho, J.J. Wang, W.J. Liaw, C.M. Ho, and J.H. Li J. Chromatogr. B 736 1999 89
19. B. Muller, and K. Wilsmann Arzneimittelforschung 34 1984 430
20. FDA guideline for submitting samples and analytical data for method validations, Rockville, MD, USA, February 1987 (http://www.fda.gov/cder. guidance).
21. L. Shargel A.B.C. Yu Applied Biopharmaceutics and Pharmacokinetics third ed. 1993 Prentice-Hall New York (Chapters 5, 9, 20)