메뉴 건너뛰기




Volumn 41, Issue 4, 2011, Pages 290-296

Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: Involvement of P-glycoprotein

Author keywords

Caco 2 cells; Coptis chinensis; isoquinoline alkaloids; MRP2; P gp; transport

Indexed keywords

BERBERINE; COPTISINE; CYCLOSPORIN A; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 2; PALMATINE; VERAPAMIL; VERLUKAST;

EID: 79952952269     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.529180     Document Type: Article
Times cited : (94)

References (39)
  • 1
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P, Karlsson J. (1991). Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun 175:880-885.
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 2
    • 0030588644 scopus 로고    scopus 로고
    • The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development
    • DOI 10.1016/S0169-409X(96)00416-4, PII S0169409X96004164
    • Bailey CA, Bryla P, Malick AW. (1996). The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development. Adv Drug Deliv Rev 22:85-103. (Pubitemid 26423599)
    • (1996) Advanced Drug Delivery Reviews , vol.22 , Issue.1-2 , pp. 85-103
    • Bailey, C.A.1    Bryla, P.2    Malick, A.W.3
  • 3
    • 79952967992 scopus 로고    scopus 로고
    • Chinese Pharmacopoeia Commission. (2010). Pharmacopoeia of the People's Republic of China. Volume I (in Chinese). Beijing, China: Chinese Medicinal Science and Technology Press
    • Chinese Pharmacopoeia Commission. (2010). Pharmacopoeia of the People's Republic of China. Volume I (in Chinese). Beijing, China: Chinese Medicinal Science and Technology Press.
  • 5
    • 33847197936 scopus 로고    scopus 로고
    • Antiviral activity of berberine and related compounds against human cytomegalovirus
    • Hayashi K, Minoda K, Nagaoka Y, Hayashi T, Uesato S. (2007). Antiviral activity of berberine and related compounds against human cytomegalovirus. Bioorg Med Chem Lett 17:1562-1564.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 1562-1564
    • Hayashi, K.1    Minoda, K.2    Nagaoka, Y.3    Hayashi, T.4    Uesato, S.5
  • 7
    • 77955172547 scopus 로고    scopus 로고
    • Identification of palmatine as an inhibitor of West Nile virus
    • Jia F, Zou G, Fan J, Yuan Z. (2010). Identification of palmatine as an inhibitor of West Nile virus. Arch Virol 155:1325-1329.
    • (2010) Arch Virol , vol.155 , pp. 1325-1329
    • Jia, F.1    Zou, G.2    Fan, J.3    Yuan, Z.4
  • 8
    • 0035105286 scopus 로고    scopus 로고
    • Monoamine oxidase inhibitors from rhizoma of Coptis chinensis
    • DOI 10.1055/s-2001-10874
    • Kong LD, Cheng CH, Tan RX. (2001). Monoamine oxidase inhibitors from rhizoma of Coptis chinensis. Planta Med 67:74-76. (Pubitemid 32199950)
    • (2001) Planta Medica , vol.67 , Issue.1 , pp. 74-76
    • Ling Dong Kong1    Cheng, C.H.K.2    Ren Xiang Tan3
  • 9
    • 0346724714 scopus 로고    scopus 로고
    • The anti-inflammatory potential of berberine in vitro and in vivo
    • Kuo CL, Chi CW, Liu TY. (2004). The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett 203:127-137.
    • (2004) Cancer Lett , vol.203 , pp. 127-137
    • Kuo, C.L.1    Chi, C.W.2    Liu, T.Y.3
  • 10
    • 33749015441 scopus 로고    scopus 로고
    • In-vitro toxicity of Ukrain against human Ewing tumor cell lines
    • DOI 10.1097/01.cad.0000231467.61911.50, PII 0000181320061000000004
    • Lanvers-Kaminsky C, Nolting DM, Köster J, Schröder A, Sandkötter J, Boos J. (2006). In-vitro toxicity of Ukrain against human Ewing tumor cell lines. Anticancer Drugs 17:1025-1030. (Pubitemid 44454779)
    • (2006) Anti-Cancer Drugs , vol.17 , Issue.9 , pp. 1025-1030
    • Lanvers-Kaminsky, C.1    Nolting, D.-M.2    Koster, J.3    Schroder, A.4    Sandkotter, J.5    Boos, J.6
  • 11
    • 34548206790 scopus 로고    scopus 로고
    • Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells
    • Lee CH, Chen JC, Hsiang CY, Wu SL, Wu HC, Ho TY. (2007). Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells. Pharmacol Res 56:193-201.
    • (2007) Pharmacol Res , vol.56 , pp. 193-201
    • Lee, C.H.1    Chen, J.C.2    Hsiang, C.Y.3    Wu, S.L.4    Wu, H.C.5    Ho, T.Y.6
  • 12
    • 32144452226 scopus 로고    scopus 로고
    • Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3
    • Lin CC, Kao ST, Chen GW, Ho HC, Chung JG. (2006). Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. Anticancer Res 26:227-242.
    • (2006) Anticancer Res , vol.26 , pp. 227-242
    • Lin, C.C.1    Kao, S.T.2    Chen, G.W.3    Ho, H.C.4    Chung, J.G.5
  • 14
    • 0034645718 scopus 로고    scopus 로고
    • Antioxidative and free radical scavenging activities of selected medicinal herbs
    • DOI 10.1016/S0024-3205(99)00643-8, PII S0024320599006438
    • Liu F, Ng TB. (2000). Antioxidative and free radical scavenging activities of selected medicinal herbs. Life Sci 66:725-735. (Pubitemid 30077865)
    • (2000) Life Sciences , vol.66 , Issue.8 , pp. 725-735
    • Liu, F.1    Ng, T.B.2
  • 15
    • 0036893418 scopus 로고    scopus 로고
    • P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers
    • Maeng HJ, Yoo HJ, Kim IW, Song IS, Chung SJ, Shim CK. (2002). P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers. J Pharm Sci 91:2614-2621.
    • (2002) J Pharm Sci , vol.91 , pp. 2614-2621
    • Maeng, H.J.1    Yoo, H.J.2    Kim, I.W.3    Song, I.S.4    Chung, S.J.5    Shim, C.K.6
  • 16
    • 0031719032 scopus 로고    scopus 로고
    • Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells
    • DOI 10.1023/A:1011971303880
    • Makhey VD, Guo A, Norris DA, Hu P, Yan J, Sinko PJ. (1998). Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharm Res 15:1160-1167. (Pubitemid 28401704)
    • (1998) Pharmaceutical Research , vol.15 , Issue.8 , pp. 1160-1167
    • Makhey, V.D.1    Guo, A.2    Norris, D.A.3    Hu, P.4    Yan, J.5    Sinko, P.J.6
  • 19
    • 36148962372 scopus 로고    scopus 로고
    • Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells
    • DOI 10.1016/j.canlet.2007.09.007, PII S0304383507004375
    • Piyanuch R, Sukhthankar M, Wandee G, Baek SJ. (2007). Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells. Cancer Lett 258:230-240. (Pubitemid 350110378)
    • (2007) Cancer Letters , vol.258 , Issue.2 , pp. 230-240
    • Piyanuch, R.1    Sukhthankar, M.2    Wandee, G.3    Baek, S.J.4
  • 20
    • 0020047678 scopus 로고
    • Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins
    • Sack RB, Froehlich JL. (1982). Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infect Immun 35:471-475. (Pubitemid 12164739)
    • (1982) Infection and Immunity , vol.35 , Issue.2 , pp. 471-475
    • Sack, R.B.1    Froehlich, J.L.2
  • 22
    • 33747090656 scopus 로고    scopus 로고
    • Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells
    • DOI 10.1016/j.ejps.2006.03.003, PII S0928098706000820
    • Seithel A, Karlsson J, Hilgendorf C, Björquist A, Ungell AL. (2006). Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells. Eur J Pharm Sci 28:291-299. (Pubitemid 44218740)
    • (2006) European Journal of Pharmaceutical Sciences , vol.28 , Issue.4 , pp. 291-299
    • Seithel, A.1    Karlsson, J.2    Hilgendorf, C.3    Bjorquist, A.4    Ungell, A.-L.5
  • 23
    • 41049098849 scopus 로고    scopus 로고
    • Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line
    • DOI 10.1007/s00280-007-0558-9
    • Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J. (2008). Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Cancer Chemother Pharmacol 61:1007-1018. (Pubitemid 351423129)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.61 , Issue.6 , pp. 1007-1018
    • Serafim, T.L.1    Oliveira, P.J.2    Sardao, V.A.3    Perkins, E.4    Parke, D.5    Holy, J.6
  • 24
    • 0027213137 scopus 로고
    • Studies on the intravenous pharmacokinetics and oral absorbtion of berberine HCl in beagle dogs
    • Shen MP, Sun Q, Wang H. (1993). Studies on the intravenous pharmacokinetics and oral absorption of berberine HCl in beagle dogs. Chin Pharmacol Bull 9:64-67. (Pubitemid 23160416)
    • (1993) Chinese Pharmacological Bulletin , vol.9 , Issue.1 , pp. 64-67
    • Shen, M.-P.1    Sun, Q.2    Wang, H.3
  • 26
    • 48449084609 scopus 로고    scopus 로고
    • Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action
    • Turner N, Li JY, Gosby A, To SW, Cheng Z, Miyoshi H, Taketo MM, Cooney GJ, Kraegen EW, James DE, Hu LH, Li J, Ye JM. (2008). Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes 57:1414-1418.
    • (2008) Diabetes , vol.57 , pp. 1414-1418
    • Turner, N.1    Li, J.Y.2    Gosby, A.3    To, S.W.4    Cheng, Z.5    Miyoshi, H.6    Taketo, M.M.7    Cooney, G.J.8    Kraegen, E.W.9    James, D.E.10    Hu, L.H.11    Li, J.12    Ye, J.M.13
  • 29
    • 1542376217 scopus 로고    scopus 로고
    • Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts
    • DOI 10.1016/j.lfs.2003.03.005, PII S002432050400044X
    • Wang S, Zheng Z, Weng Y, Yu Y, Zhang D, Fan W, Dai R, Hu Z. (2004). Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts. Life Sci 74:2467-2478. (Pubitemid 38324603)
    • (2004) Life Sciences , vol.74 , Issue.20 , pp. 2467-2478
    • Wang, S.1    Zheng, Z.2    Weng, Y.3    Yu, Y.4    Zhang, D.5    Fan, W.6    Dai, R.7    Hu, Z.8
  • 30
    • 34547951639 scopus 로고    scopus 로고
    • Effects of berberine on the transport of P-gp substrates across Caco-2 and L-MDR1 cell monolayers
    • Xin HW, Wu XC, Li Q, Yu AR, Ulrich Klotz. (2007). Effects of berberine on the transport of P-gp substrates across Caco-2 and L-MDR1 cell monolayers. Chin Pharmacol Bull 23:799-803.
    • (2007) Chin Pharmacol Bull , vol.23 , pp. 799-803
    • Xin, H.W.1    Wu, X.C.2    Li, Q.3    Yu, A.R.4    Ulrich, Klotz.5
  • 31
    • 48649105820 scopus 로고    scopus 로고
    • Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry
    • Yan D, Jin C, Xiao XH, Dong XP. (2008). Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry. J Biochem Biophys Methods 70:845-849.
    • (2008) J Biochem Biophys Methods , vol.70 , pp. 845-849
    • Yan, D.1    Jin, C.2    Xiao, X.H.3    Dong, X.P.4
  • 32
    • 0345098540 scopus 로고    scopus 로고
    • Transport and uptake characteristics of a new derivative of berberine (CPU-86017) by human intestinal epithelial cell line: Caco-2
    • Yang HT, Wang GJ. (2003). Transport and uptake characteristics of a new derivative of berberine (CPU-86017) by human intestinal epithelial cell line: Caco-2. Acta Pharmacol Sin 24:1185-1191. (Pubitemid 37509422)
    • (2003) Acta Pharmacologica Sinica , vol.24 , Issue.12 , pp. 1185-1191
    • Yang, H.-T.1    Wang, G.J.2
  • 33
    • 38349006242 scopus 로고    scopus 로고
    • Berberine improves glucose metabolism through induction of glycolysis
    • Yin J, Gao Z, Liu D, Liu Z, Ye J. (2008). Berberine improves glucose metabolism through induction of glycolysis. Am J Physiol Endocrinol Metab 294:E148-E156.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Yin, J.1    Gao, Z.2    Liu, D.3    Liu, Z.4    Ye, J.5
  • 36
    • 0007976196 scopus 로고    scopus 로고
    • Determination and preliminary studies of metabolism of berberine in human urine after oral administration
    • Yu S, Zhang H, PanJun F, Hong Y, Ren J, Zhu D, and Xu X. (2000). Determination and preliminary studies of metabolism of berberine in human urine after oral administration. Chin J Clin Pharmacol 16:36-39.
    • (2000) Chin J Clin Pharmacol , vol.16 , pp. 36-39
    • Yu, S.1    Zhang, H.2    PanJun, F.3    Hong, Y.4    Ren, J.5    Zhu, D.6    Xu, X.7
  • 37
    • 33749665999 scopus 로고    scopus 로고
    • Hypoglycemic and hypocholesterolemic effects of Coptis chinensis franch inflorescence
    • DOI 10.1007/s11130-006-0023-7
    • Yuan L, Tu D, Ye X, Wu J. (2006). Hypoglycemic and hypocholesterolemic effects of Coptis chinensis franch inflorescence. Plant Foods Hum Nutr 61:139-144. (Pubitemid 44554870)
    • (2006) Plant Foods for Human Nutrition , vol.61 , Issue.3 , pp. 139-144
    • Yuan, L.1    Tu, D.2    Ye, X.3    Wu, J.4
  • 39
    • 33751511999 scopus 로고    scopus 로고
    • Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry
    • DOI 10.1124/dmd.106.011361
    • Zuo F, Nakamura N, Akao T, Hattori M. (2006). Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metab Dispos 34:2064-2072. (Pubitemid 44837767)
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.12 , pp. 2064-2072
    • Zuo, F.1    Nakamura, N.2    Akao, T.3    Hattori, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.