-
1
-
-
0037229076
-
Targeting the epidermal growth factor receptor in cancer: Apoptosis takes center stage
-
Kari C, Chan TO, Rocha de Quadros M, Rodeck U. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res 2003; 63: 1-5.
-
(2003)
Cancer Res
, vol.63
, pp. 1-5
-
-
Kari, C.1
Chan, T.O.2
Rocha De Quadros, M.3
Rodeck, U.4
-
2
-
-
58149376976
-
The epidermal growth factor receptor ligands at a glance
-
Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a glance. J Cell Physiol 2009; 218: 460-466.
-
(2009)
J Cell Physiol
, vol.218
, pp. 460-466
-
-
Schneider, M.R.1
Wolf, E.2
-
3
-
-
4344687434
-
Anoikis: Cancer and the homeless cell
-
Liotta LA, Kohn E. Anoikis: cancer and the homeless cell. Nature 2004; 430: 973-974.
-
(2004)
Nature
, vol.430
, pp. 973-974
-
-
Liotta, L.A.1
Kohn, E.2
-
4
-
-
4344627055
-
Peeper DS Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
-
Douma S, Van Laar T, Zevenhoven J, Meuwissen R, Van Garderen E. Peeper DS Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 2004; 430: 1034-1039.
-
(2004)
Nature
, vol.430
, pp. 1034-1039
-
-
Douma, S.1
Van Laar, T.2
Zevenhoven, J.3
Meuwissen, R.4
Van Garderen, E.5
-
5
-
-
34248594553
-
Metastasis: Recent discoveries and novel treatment strategies
-
Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies. Lancet 2007; 369: 1742-1757.
-
(2007)
Lancet
, vol.369
, pp. 1742-1757
-
-
Eccles, S.A.1
Welch, D.R.2
-
6
-
-
34848855124
-
The MET receptor tyrosine kinase in invasion and metastasis
-
Benvenuti S, Comoglio PM. The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol 2007; 213: 316-325.
-
(2007)
J Cell Physiol
, vol.213
, pp. 316-325
-
-
Benvenuti, S.1
Comoglio, P.M.2
-
7
-
-
34447123807
-
Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis
-
Geiger TR, Peeper DS. Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis. Cancer Res 2007; 67: 6221-6229.
-
(2007)
Cancer Res
, vol.67
, pp. 6221-6229
-
-
Geiger, T.R.1
Peeper, D.S.2
-
8
-
-
0042696985
-
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
-
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J et al. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 2003; 5: 733-740.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 733-740
-
-
Reginato, M.J.1
Mills, K.R.2
Paulus, J.K.3
Lynch, D.K.4
Sgroi, D.C.5
Debnath, J.6
-
9
-
-
59649107705
-
Functions and mechanisms of action of CCN matricellular proteins
-
Chen CC, Lau LF. Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol 2009; 41: 771-783.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 771-783
-
-
Chen, C.C.1
Lau, L.F.2
-
10
-
-
38349061659
-
CCN2, the connective tissue growth factor
-
Luft FC. CCN2, the connective tissue growth factor. J Mol Med 2008; 86: 1-3.
-
(2008)
J Mol Med
, vol.86
, pp. 1-3
-
-
Luft, F.C.1
-
11
-
-
56349143203
-
Connective tissue growth factor (CTGF) and cancer progression
-
Chu CY, Chang CC, Prakash E, Kuo ML. Connective tissue growth factor (CTGF) and cancer progression. J Biomed Sci 2008; 15: 675-685.
-
(2008)
J Biomed Sci
, vol.15
, pp. 675-685
-
-
Chu, C.Y.1
Chang, C.C.2
Prakash, E.3
Kuo, M.L.4
-
12
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3: 537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
-
13
-
-
1642350329
-
Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas
-
Xie D, Yin D, Wang HJ, Liu GT, Elashoff R, Black K et al. Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas. Clin Cancer Res 2004; 10: 2072-2081.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2072-2081
-
-
Xie, D.1
Yin, D.2
Wang, H.J.3
Liu, G.T.4
Elashoff, R.5
Black, K.6
-
14
-
-
0036548760
-
Connective tissue growth factor gene expression alters tumor progression in esophageal cancer
-
Koliopanos A, Friess H, di Mola FF, Tang WH, Kubulus D, Brigstock D et al. Connective tissue growth factor gene expression alters tumor progression in esophageal cancer. World J Surg 2002; 26: 420-427.
-
(2002)
World J Surg
, vol.26
, pp. 420-427
-
-
Koliopanos, A.1
Friess, H.2
Di Mola, F.F.3
Tang, W.H.4
Kubulus, D.5
Brigstock, D.6
-
15
-
-
35148849800
-
Expression of connective tissue growth factor is in agreement with the expression of VEGF, VEGF-C, -D and associated with shorter survival in gastric cancer
-
Liu L, Li Z, Feng G, You W, Li J. Expression of connective tissue growth factor is in agreement with the expression of VEGF, VEGF-C, -D and associated with shorter survival in gastric cancer. Pathol Int 2007; 57: 712-718.
-
(2007)
Pathol Int
, vol.57
, pp. 712-718
-
-
Liu, L.1
Li, Z.2
Feng, G.3
You, W.4
Li, J.5
-
16
-
-
9244232781
-
Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance
-
Zeng ZJ, Yang LY, Ding X, Wang W. Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance. World J Gastroenterol 2004; 10: 3414-3418.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3414-3418
-
-
Zeng, Z.J.1
Yang, L.Y.2
Ding, X.3
Wang, W.4
-
17
-
-
11144332958
-
Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer
-
Lin BR, Chang CC, Che TF, Chen ST, Chen RJ, Yang CY et al. Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer. Gastroenterology 2005; 128: 9-23.
-
(2005)
Gastroenterology
, vol.128
, pp. 9-23
-
-
Lin, B.R.1
Chang, C.C.2
Che, T.F.3
Chen, S.T.4
Chen, R.J.5
Yang, C.Y.6
-
18
-
-
1542288151
-
Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis
-
Chang CC, Shih JY, Jeng YM, Su JL, Lin BZ, Chen ST et al. Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis. J Natl Cancer Inst 2004; 96: 364-375.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 364-375
-
-
Chang, C.C.1
Shih, J.Y.2
Jeng, Y.M.3
Su, J.L.4
Lin, B.Z.5
Chen, S.T.6
-
19
-
-
33746776975
-
Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis
-
Chang CC, Lin MT, Lin BR, Jeng YM, Chen ST, Chu CY et al. Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis. J Natl Cancer Inst 2006; 98: 984-995.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 984-995
-
-
Chang, C.C.1
Lin, M.T.2
Lin, B.R.3
Jeng, Y.M.4
Chen, S.T.5
Chu, C.Y.6
-
20
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
Ogiso H, Ishitani R, Nureki O, Fukai S, Yamanaka M, Kim JH et al. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 2002; 110: 775-787.
-
(2002)
Cell
, vol.110
, pp. 775-787
-
-
Ogiso, H.1
Ishitani, R.2
Nureki, O.3
Fukai, S.4
Yamanaka, M.5
Kim, J.H.6
-
21
-
-
41249094559
-
Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization
-
Schmiedel J, Blaukat A, Li S, Kno chel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell 2008; 13: 365-373.
-
(2008)
Cancer Cell
, vol.13
, pp. 365-373
-
-
Schmiedel, J.1
Blaukat, A.2
Li, S.3
Kno Chel, T.4
Ferguson, K.M.5
-
22
-
-
70349758510
-
Src kinases as therapeutic targets for cancer
-
Kim LC, Song L, Haura EB. Src kinases as therapeutic targets for cancer. Nat Rev Clin Oncol 2009; 6: 587-595.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 587-595
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
23
-
-
0029165834
-
Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor
-
Muthuswamy SK, Muller WJ. Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor. Oncogene 1995; 11: 271-279.
-
(1995)
Oncogene
, vol.11
, pp. 271-279
-
-
Muthuswamy, S.K.1
Muller, W.J.2
-
24
-
-
34548023897
-
Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized
-
Padron D, Sato M, Shay JW, Gazdar AF, Minna JD, Roth MG. Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized. Cancer Res 2007; 67: 7695-7702.
-
(2007)
Cancer Res
, vol.67
, pp. 7695-7702
-
-
Padron, D.1
Sato, M.2
Shay, J.W.3
Gazdar, A.F.4
Minna, J.D.5
Roth, M.G.6
-
25
-
-
42349108970
-
A tale of two Cbls: Interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation
-
Pennock S, Wang Z. A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation. Mol Cell Biol 2008; 28: 3020-3037.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3020-3037
-
-
Pennock, S.1
Wang, Z.2
-
26
-
-
54249151578
-
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
-
Umebayashi K, Stenmark H, Yoshimori T. Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation. Mol Biol Cell 2008; 19: 3454-3462.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3454-3462
-
-
Umebayashi, K.1
Stenmark, H.2
Yoshimori, T.3
-
27
-
-
0141426629
-
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation
-
Wu WJ, Tu S, Cerione RA. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell 2003; 114: 715-725.
-
(2003)
Cell
, vol.114
, pp. 715-725
-
-
Wu, W.J.1
Tu, S.2
Cerione, R.A.3
-
28
-
-
33748136028
-
Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth
-
Feng Q, Baird D, Peng X, Wang J, Ly T, Guan JL et al. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nat Cell Biol 2006; 8: 945-956.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 945-956
-
-
Feng, Q.1
Baird, D.2
Peng, X.3
Wang, J.4
Ly, T.5
Guan, J.L.6
-
29
-
-
49649109588
-
SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis
-
Yamaguchi H, Woods NT, Dorsey JF, Takahashi Y, Gjertsen NR, Yeatman T et al. SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis. J Biol Chem 2008; 283: 19112-19118.
-
(2008)
J Biol Chem
, vol.283
, pp. 19112-19118
-
-
Yamaguchi, H.1
Woods, N.T.2
Dorsey, J.F.3
Takahashi, Y.4
Gjertsen, N.R.5
Yeatman, T.6
-
30
-
-
79951843117
-
Recovery of anoikis in Src-transformed cells and human breast carcinoma cells by restoration of the SIRP{alpha}1/SHP-2 signaling system
-
Hara K, Senga T, Biswas MH, Hasegawa H, Ito S, Hyodo T et al. Recovery of anoikis in Src-transformed cells and human breast carcinoma cells by restoration of the SIRP{alpha}1/SHP-2 signaling system. Cancer Res 2011; 71: 1229-1234.
-
(2011)
Cancer Res
, vol.71
, pp. 1229-1234
-
-
Hara, K.1
Senga, T.2
Biswas, M.H.3
Hasegawa, H.4
Ito, S.5
Hyodo, T.6
-
31
-
-
58149186477
-
PID: The pathway interaction database
-
Schaefer CF, Anthony K, Krupa S, Buchoff J, Day M, Hannay T et al. PID: the pathway interaction database. Nucleic Acids Res 2009; 37: D674-D679.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Schaefer, C.F.1
Anthony, K.2
Krupa, S.3
Buchoff, J.4
Day, M.5
Hannay, T.6
-
32
-
-
0030664814
-
DAP kinase links the control of apoptosis to metastasis
-
Inbal B, Cohen O, Polak-Charcon S, Kopolovic J, Vadai E, Eisenbach L et al. DAP kinase links the control of apoptosis to metastasis. Nature 1997; 390: 180-184.
-
(1997)
Nature
, vol.390
, pp. 180-184
-
-
Inbal, B.1
Cohen, O.2
Polak-Charcon, S.3
Kopolovic, J.4
Vadai, E.5
Eisenbach, L.6
-
33
-
-
33645364659
-
The tumor suppressor DAP-kinase links cell adhesion and cytoskeleton reorganization to cell death regulation
-
Chen RH, Wang WJ, Kuo JC. The tumor suppressor DAP-kinase links cell adhesion and cytoskeleton reorganization to cell death regulation. J Biomed Sci 2006; 13: 193-199.
-
(2006)
J Biomed Sci
, vol.13
, pp. 193-199
-
-
Chen, R.H.1
Wang, W.J.2
Kuo, J.C.3
-
34
-
-
0942287209
-
Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells
-
Singh AB, Harris RC. Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells. J Biol Chem 2004; 279: 3543-3552.
-
(2004)
J Biol Chem
, vol.279
, pp. 3543-3552
-
-
Singh, A.B.1
Harris, R.C.2
-
35
-
-
0028307058
-
Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond
-
Sorokin A, Lemmon MA, Ullrich A, Schlessinger J. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond. J Biol Chem 1994; 269: 9752-9759.
-
(1994)
J Biol Chem
, vol.269
, pp. 9752-9759
-
-
Sorokin, A.1
Lemmon, M.A.2
Ullrich, A.3
Schlessinger, J.4
-
36
-
-
34548249520
-
The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR
-
Wang WJ, Kuo JC, Ku W, Lee YR, Lin FC, Chang YL et al. The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR. Mol Cell 2007; 27: 701-716.
-
(2007)
Mol Cell
, vol.27
, pp. 701-716
-
-
Wang, W.J.1
Kuo, J.C.2
Ku, W.3
Lee, Y.R.4
Lin, F.C.5
Chang, Y.L.6
|