Recovery of anoikis in Src-transformed cells and human breast carcinoma cells by restoration of the SIRPα1/SHP-2 signaling system

Cancer Research

Volumn 71, Issue 4, 2011, Pages 1229-1234

  Hara, Kazuo ^a   Senga, Takeshi ^a   Biswas, Md Helal Uddin ^a   Hasegawa, Hitoki ^a   Ito, Satoko ^a   Hyodo, Toshinori ^a   Hirooka, Yoshiki ^a   Niwa, Yasumasa ^a   Goto, Hidemi ^a   Hamaguchi, Michinari ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE SHP 2; SIGNAL REGULATORY PROTEIN ALPHA 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANOIKIS; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CELL CYCLE ARREST; CONTROLLED STUDY; ENZYME REPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; STRESS FIBER;

ANIMALS; ANOIKIS; ANTIGENS, DIFFERENTIATION; BREAST NEOPLASMS; CARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 79951843117     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-3431     Document Type: Article

References (19)

1. Jove R, Hanafusa H. Cell transformation by the viral src oncogene. Annu Rev Cell Biol 1987;3:31-56.
2. Machida K, Matsuda S, Yamaki K, Senga T, Thant AA, Kurata H, et al. v-Src suppresses SHPS-1 expression via the Ras-MAP kinase pathway to promote the oncogenic growth of cells. Oncogene 2000; 19:1710-8. (Pubitemid 30200973)
3. Yamasaki Y, Ito S, Tsunoda N, Kokuryo T, Hara K, Senga T, et al. SIRPalpha1 and SIRPalpha2: their role as tumor suppressors in breast carcinoma cells. Biochem Biophys Res Commun 2007;361:7-13. (Pubitemid 47102261)
4. Van Den Berg TK, van Beek EM, Barclay AN, Buhring HJ, Colonna M, Hamaguchi M, et al. A nomenclature for signal regulatory protein family members. J Immunol 2005:175:7788-9. (Pubitemid 41798336)
5. Oshima K, Ruhul Amin AR, Suzuki A, Hamaguchi M, Matsuda S. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett 2002;519:1-7. (Pubitemid 34521982)
6. Kharitonenkov A, Chen Z, Sures I, Wang H, Schilling J, Ullrich A. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature 1997;386:181-6. (Pubitemid 27131446)
7. Feng GS. Shp-2 tyrosine phosphatase: signaling one cell or many. Exp Cell Res 1999;253:47-54.
8. Hof P, Pluskey S, Dhe-Paganon S, Eck MJ, Shoelson SE. Crystal structure of the tyrosine phosphatase SHP-2. Cell 1998;92:441-50. (Pubitemid 28101108)
9. Chong ZZ, Maiese K. The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury. Histol Histopathol 2007;22:1251-67. (Pubitemid 47470319)
10. Dance M, Montagner A, Salles JP, Yart A, Raynal P. The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway. Cell Signal 2008;20:453-9.
11. Matozaki T, Murata Y, Saito Y, Okazawa H, Ohnishi H. Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation. Cancer Sci 2009;100:1786-93.
12. Hakak Y, Hsu YS, Martin GS. Shp-2 mediates v-Src-induced morphological changes and activation of the anti-apoptotic protein kinase Akt. Oncogene 2000;19:3164-71. (Pubitemid 30455928)
13. Lo FS, Kuo TT, Wang CJ, Kuo MT, Kuo MC. Hodgkin's lymphoma in a patient with Noonan syndrome with germ-line PTPN11 mutations. Int J Hematol 2008;88:287-90.
14. Frisch SM, Screaton RA. Anoikis mechanisms. Curr Opin Cell Biol 2001;13:555-62. (Pubitemid 32817013)
15. Chiarugi P, Giannoni E. Anoikis: a necessary death program for anchorage-dependent cells. Biochem Pharmacol 2008;76:1352-64.
16. Mon NN, Hasegawa H, Thant AA, Huang P, Tanimura Y. Senga T, et al. A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1.Cancer Res 2006: 66:6778-84. (Pubitemid 44085637)
17. Liu Y, Hiraiwa Y, Liu E, Kurata H, Thant AA, Matsuda S, et al. Suppression of cell spreading by v-Crk requires Ras-MEK-MAP kinase signaling. Oncogene. 2001;20:5908-12. (Pubitemid 32937961)
18. Kokuryo T, Senga T, Yokoyama Y, Nagino M, Nimura Y, Hamaguchi M. Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma. Cancer Res. 2007;67:9637-42 (Pubitemid 47621209)
19. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999;15:269-90. (Pubitemid 32250377)