Uridine phosphorylase inhibitors: Chemical modification of benzyloxybenzyl-barbituric acid and its effects on UrdPase inhibition

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 11, 1999, Pages 1477-1480

  Guerin, David J ^a   Mazeas, Daniel ^a   Musale, Manoj S ^a   Naguib, Fardos N M ^b   Al Safarjalani, Omar N ^b   El Kouni, Mahmoud H ^b   Panzica, Raymond P ^a  

^a University of Rhode Island   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 BENZYLOXY)BENZYLBARBITURIC ACID; 5 (3 BENZYLOXY)BENZYL 2 THIOBARBITURIC ACID; 5 (3 BENZYLOXY)BENZYLBARBITURIC ACID; 5 (4 BENZYLOXY)BENZYLBARBITURIC ACID; BARBITURIC ACID DERIVATIVE; BENZYL DERIVATIVE; UNCLASSIFIED DRUG; URIDINE PHOSPHORYLASE;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INACTIVATION; SYNTHESIS;

EID: 0033532552     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00238-3     Document Type: Article

References (6)

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2. Naquib, F. N. M.; Levesque, D. L.; Wang, E.-C.; Panzica, R. P.; el Kouni, M. H. Biochem. Pharmacol. 1993, 46, 1273.
3. Niedzwicki, J. G.; el Kouni, M. H.; Chu, S. H.; Cha, S. Biochem. Pharmacol. 1983, 32, 399.
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